EVpedia provide top 100+ EV markers, selected according to their identification number.
Based on EV proteomes, we defined the identification number of protein A as the number of datasets which contain protein A.
Therefore, proteins with higher identification numbers were more conserved.

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Protein name Gene symbol UniProt accession Identification number
Centrin-3CETN3 CEN3O151824
Centriole, cilia and spindle-associated proteinCCSAP C1orf96 CSAPQ6IQ194
Centriolin (Centrosomal protein 1) (Centrosomal protein of 110 kDa) (Cep110)CNTRL CEP1 CEP110Q7Z7A14
Centrobin (Centrosomal BRCA2-interacting protein) (LYST-interacting protein 8)CNTROB LIP8 PP1221Q8N1374
Centromere protein W (CENP-W) (Cancer-up-regulated gene 2 protein)CENPW C6orf173 CUG2Q5EE014
Centromere-associated protein E (Centromere protein E) (CENP-E) (Kinesin-related protein CENPE)CENPEQ022244
Centromere/kinetochore protein zw10 homologZW10O432644
Centrosomal protein of 164 kDa (Cep164)CEP164 KIAA1052 NPHP15Q9UPV04
Centrosomal protein of 19 kDa (Cep19)CEP19 C3orf34 HSD5Q96LK04
Centrosomal protein of 41 kDa (Cep41) (Testis-specific gene A14 protein)CEP41 TSGA14Q9BYV84
Centrosome and spindle pole-associated protein 1CSPP1 CSPPQ1MSJ54
Ceramide-1-phosphate transfer protein (Glycolipid transfer protein domain-containing protein 1) (CPTP)GLTPD1Q5TA504
Ceroid-lipofuscinosis neuronal protein 6 (Protein CLN6)CLN6Q9NWW54
Charged multivesicular body protein 1b (CHMP1.5) (Chromatin-modifying protein 1b) (CHMP1b) (Vacuolar protein sorting-associated protein 46-2) (Vps46-2) (hVps46-2)CHMP1B C18orf2Q7LBR14
Charged multivesicular body protein 6 (Chromatin-modifying protein 6) (Vacuolar protein sorting-associated protein 20) (Vps20) (hVps20)CHMP6 VPS20Q96FZ74
Chitinase-3-like protein 1 (39 kDa synovial protein) (Cartilage glycoprotein 39) (CGP-39) (GP-39) (hCGP-39) (YKL-40)CHI3L1P362224
Chloride intracellular channel protein 3CLIC3O958334
Choline-phosphate cytidylyltransferase A (EC 2.7.7.15) (CCT-alpha) (CTP:phosphocholine cytidylyltransferase A) (CCT A) (CT A) (Phosphorylcholine transferase A)PCYT1A CTPCT PCYT1P495854
Chordin-like protein 2 (Breast tumor novel factor 1) (BNF-1) (Chordin-related protein 2)CHRDL2 BNF1 CHL2 UNQ765/PRO1557Q6WN344
Choriogonadotropin subunit beta variant 1CGB1A6NKQ94
Chorionic somatomammotropin hormone (Choriomammotropin) (Lactogen) (Placental lactogen) (PL)CSH1; CSH2P012434
Chromosome 16 open reading frame 35 (HCG1984129, isoform CRA_c) (cDNA FLJ33398 fis, clone BRACE2009558, highly similar to CGTHBA protein)C16orf35 hCG_1984129Q9BTE24
Chromosome alignment-maintaining phosphoprotein 1 (Zinc finger protein 828)CHAMP1 C13orf8 CAMP KIAA1802 ZNF828Q96JM34
Citrate lyase subunit beta-like protein, mitochondrial (Citrate lyase beta-like) (EC 4.1.-.-)CLYBL CLBQ8N0X44
CKLF-like MARVEL transmembrane domain-containing protein 1 (Chemokine-like factor superfamily member 1)CMTM1 CKLFSF1Q8IZ964
CKLF-like MARVEL transmembrane domain-containing protein 8 (Chemokine-like factor superfamily member 8)CMTM8 CKLFSF8Q8IZV24
Clathrin heavy chain 1 (Clathrin heavy chain on chromosome 17) (CLH-17)CLTC CLH17 CLTCL2 KIAA0034Q006104
Claudin-5 (Transmembrane protein deleted in VCFS) (TMDVCF)CLDN5 AWAL TMVCFO005014
Cleavage and polyadenylation specificity factor subunit 6 (Cleavage and polyadenylation specificity factor 68 kDa subunit) (CFIm68) (CPSF 68 kDa subunit) (Pre-mRNA cleavage factor Im 68 kDa subunit) (Protein HPBRII-4/7)CPSF6 CFIM68Q166304
CLIC4 protein (Chloride intracellular channel 4, isoform CRA_b) (cDNA, FLJ96000, Homo sapiens chloride intracellular channel 4 (CLIC4), mRNA)CLIC4 hCG_24047Q6FIC54
CLK2 protein (Fragment)CLK2Q9BRG84
CLK4-associating serine/arginine rich protein (Splicing factor, arginine/serine-rich 16) (Suppressor of white-apricot homolog 2)CLASRP SFRS16 SWAP2 UNQ2428/PRO4988Q8N2M84
CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 2 (Alpha 2,3-ST 2) (Beta-galactoside alpha-2,3-sialyltransferase 2) (EC 2.4.99.4) (Gal-NAc6S) (Gal-beta-1,3-GalNAc-alpha-2,3-sialyltransferase) (ST3Gal II) (ST3GalII) (ST3GalA.2) (Sialyltransferase 4B) (SIAT4-B)ST3GAL2 SIAT4BQ168424
CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 4 (Alpha 2,3-ST 4) (Beta-galactoside alpha-2,3-sialyltransferase 4) (EC 2.4.99.-) (Alpha 2,3-sialyltransferase IV) (Gal-NAc6S) (Gal-beta-1,4-GalNAc-alpha-2,3-sialyltransferase) (SAT-3) (ST-4) (ST3Gal IV) (ST3GalIV) (ST3GalA.2) (STZ) (Sialyltransferase 4C) (SIAT4-C)ST3GAL4 CGS23 NANTA3 SIAT4C STZQ112064
Coagulation factor V (Activated protein C cofactor) (Proaccelerin, labile factor) [Cleaved into: Coagulation factor V heavy chain; Coagulation factor V light chain]F5P122594
Coatomer subunit zeta-2 (Zeta-2-coat protein) (Zeta-2 COP)COPZ2Q9P2994
Cohesin subunit SA-1 (SCC3 homolog 1) (Stromal antigen 1)STAG1 SA1Q8WVM74
Coiled-coil domain-containing protein 104CCDC104 UNQ163/PRO189Q96G284
Coiled-coil domain-containing protein 113CCDC113 HSPC065Q9H0I34
Coiled-coil domain-containing protein 115CCDC115Q96NT04
Coiled-coil domain-containing protein 149CCDC149Q6ZUS64
Coiled-coil domain-containing protein 171CCDC171 C9orf93Q6TFL34
Coiled-coil domain-containing protein 181CCDC181 C1orf114Q5TID74
Coiled-coil domain-containing protein 23CCDC23Q8N3004
Coiled-coil domain-containing protein 92 (Limkain beta-2)CCDC92Q53HC04
Coiled-coil domain-containing protein 97CCDC97Q96F634
Coiled-coil domain-containing protein C16orf93C16orf93A1A4V94
Coiled-coil-helix-coiled-coil-helix domain-containing protein 10, mitochondrial (Protein N27C7-4)CHCHD10 C22orf16Q8WYQ34
Cold shock domain-containing protein C2 (RNA-binding protein PIPPin)CSDC2 PIPPINQ9Y5344
Collagen alpha-1(XXVII) chainCOL27A1 KIAA1870Q8IZC64
COMM domain-containing protein 8COMMD8 MDS022Q9NX084
Complement factor D (EC 3.4.21.46) (Adipsin) (C3 convertase activator) (Properdin factor D)CFD DF PFDP007464
Conserved oligomeric Golgi complex subunit 2 (COG complex subunit 2) (Component of oligomeric Golgi complex 2) (Low density lipoprotein receptor defect C-complementing protein)COG2 LDLCQ147464
ConsortinCNST C1orf71Q6PJW84
Coordinator of PRMT5 and differentiation stimulator (Cooperator of PRMT5) (Protein TTP1)COPRS C17orf79 COPR5Q9NQ924
Core histone macro-H2A.2 (Histone macroH2A2) (mH2A2)H2AFY2 MACROH2A2Q9P0M64
Corepressor interacting with RBPJ 1 (CBF1-interacting corepressor) (Recepin)CIR1 CIRQ86X954
Coronin-1C (Coronin-3) (hCRNN4)CORO1C CRN2 CRNN4Q9ULV44
COX8 protein (Cytochrome c oxidase subunit 8A (Ubiquitous)) (Cytochrome c oxidase subunit VIII) (cDNA, FLJ92201, Homo sapiens cytochrome c oxidase subunit VIII (COX8), mRNA)COX8A COX8 hCG_27157Q53XN14
Coxsackievirus and adenovirus receptor (CAR) (hCAR) (CVB3-binding protein) (Coxsackievirus B-adenovirus receptor) (HCVADR)CXADR CARP783104
Cryptochrome-1CRY1 PHLL1Q165264
CTD small phosphatase-like protein 2 (CTDSP-like 2) (EC 3.1.3.-)CTDSPL2 HSPC058 HSPC129Q05D324
CUGBP Elav-like family member 5 (CELF-5) (Bruno-like protein 5) (CUG-BP- and ETR-3-like factor 5) (RNA-binding protein BRUNOL-5)CELF5 BRUNOL5Q8N6W04
Cullin-associated NEDD8-dissociated protein 2 (Cullin-associated and neddylation-dissociated protein 2) (Epididymis tissue protein Li 169) (TBP-interacting protein of 120 kDa B) (TBP-interacting protein 120B) (p120 CAND2)CAND2 KIAA0667 TIP120BO751554
CXXC-type zinc finger protein 11CXXC11 C2orf85Q14D334
Cyclic AMP-dependent transcription factor ATF-2 (cAMP-dependent transcription factor ATF-2) (EC 2.3.1.48) (Activating transcription factor 2) (Cyclic AMP-responsive element-binding protein 2) (CREB-2) (cAMP-responsive element-binding protein 2) (HB16) (Histone acetyltransferase ATF2) (cAMP response element-binding protein CRE-BP1)ATF2 CREB2 CREBP1P153364
Cyclic AMP-responsive element-binding protein 3-like protein 3 (cAMP-responsive element-binding protein 3-like protein 3) (Transcription factor CREB-H) [Cleaved into: Processed cyclic AMP-responsive element-binding protein 3-like protein 3]CREB3L3 CREBH HYST1481Q68CJ94
Cyclin-dependent kinase 4 inhibitor C (Cyclin-dependent kinase 6 inhibitor) (p18-INK4c) (p18-INK6)CDKN2C CDKN6P427734
Cyclin-KCCNK CPR4O759094
Cyclin-Y-like protein 1CCNYL1Q8N7R74
Cysteine and histidine-rich protein 1CYHR1 KIAA0496Q6ZMK14
Cysteine-rich PAK1 inhibitor (CRIPak)CRIPAKQ8N1N54
Cysteine/serine-rich nuclear protein 1 (CSRNP-1) (Axin-1 up-regulated gene 1 protein) (Protein URAX1) (TGF-beta-induced apoptosis protein 3) (TAIP-3)CSRNP1 AXUD1 TAIP3Q96S654
Cystine/glutamate transporter (Amino acid transport system xc-) (Calcium channel blocker resistance protein CCBR1) (Solute carrier family 7 member 11) (xCT)SLC7A11Q9UPY54
Cytochrome b ascorbate-dependent protein 3 (EC 1.-.-.-) (Cytochrome b561 family member A3) (Lysosomal cytochrome b) (LCytb)CYB561A3 CYBASC3 LCYTB PSEC0259Q8NBI24
Cytochrome b-245 light chain (Cytochrome b(558) alpha chain) (Cytochrome b558 subunit alpha) (Neutrophil cytochrome b 22 kDa polypeptide) (Superoxide-generating NADPH oxidase light chain subunit) (p22 phagocyte B-cytochrome) (p22-phox) (p22phox)CYBAP134984
Cytochrome c oxidase assembly protein 1 homolog (Mitochondrial translation regulation assembly intermediate of cytochrome c oxidase protein of 15 kDa)COA1 C7orf44 MITRAC15Q9GZY44
Cytochrome c oxidase assembly protein COX11, mitochondrialCOX11Q9Y6N14
Cytochrome c oxidase assembly protein COX14COX14 C12orf62Q96I364
Cytochrome c oxidase subunit 1 (EC 1.9.3.1) (Cytochrome c oxidase polypeptide I)MT-CO1 COI COXI MTCO1P003954
Cytochrome P450 1A2 (EC 1.14.14.1) (CYPIA2) (Cytochrome P(3)450) (Cytochrome P450 4) (Cytochrome P450-P3)CYP1A2P051774
Cytochrome P450 2A13 (EC 1.14.14.1) (CYPIIA13)CYP2A13Q166964
Cytochrome P450 4V2 (EC 1.14.13.-)CYP4V2Q6ZWL34
Cytoplasmic dynein 1 heavy chain 1 (Cytoplasmic dynein heavy chain 1) (Dynein heavy chain, cytosolic)DYNC1H1 DHC1 DNCH1 DNCL DNECL DYHC KIAA0325Q142044
Cytoplasmic polyadenylation element-binding protein 3 (CPE-BP3) (CPE-binding protein 3) (hCPEB-3)CPEB3 KIAA0940Q8NE354
Cytoplasmic protein NCK1 (NCK adaptor protein 1) (Nck-1) (SH2/SH3 adaptor protein NCK-alpha)NCK1 NCKP163334
Cytoplasmic tRNA 2-thiolation protein 1 (EC 2.7.7.-) (ATP-binding domain-containing protein 3) (Cancer-associated gene protein) (Cytoplasmic tRNA adenylyltransferase 1)CTU1 ATPBD3 NCS6Q7Z7A34
Cytoskeleton-associated protein 2 (CTCL tumor antigen se20-10) (Tumor- and microtubule-associated protein)CKAP2 LB1 TMAPQ8WWK94
Cytosol aminopeptidase (EC 3.4.11.1) (Leucine aminopeptidase 3) (LAP-3) (Leucyl aminopeptidase) (Peptidase S) (Proline aminopeptidase) (EC 3.4.11.5) (Prolyl aminopeptidase)LAP3 LAPEP PEPSP288384
Cytosolic beta-glucosidase (EC 3.2.1.21) (Cytosolic beta-glucosidase-like protein 1)GBA3 CBG CBGL1Q9H2274
Cytosolic carboxypeptidase 1 (EC 3.4.17.-) (ATP/GTP-binding protein 1) (Nervous system nuclear protein induced by axotomy protein 1 homolog)AGTPBP1 CCP1 KIAA1035 NNA1Q9UPW54
Cytosolic Fe-S cluster assembly factor NARFL (Iron-only hydrogenase-like protein 1) (IOP1) (Nuclear prelamin A recognition factor-like protein) (Protein related to Narf)NARFL PRNQ9H6Q44
D site-binding protein (Albumin D box-binding protein) (Albumin D-element-binding protein) (Tax-responsive enhancer element-binding protein 302) (TaxREB302)DBPQ105864
DDB1- and CUL4-associated factor 10 (WD repeat-containing protein 32)DCAF10 WDR32Q5QP824
Death domain-containing protein CRADD (Caspase and RIP adapter with death domain) (RIP-associated protein with a death domain)CRADD RAIDDP785604
Death-associated protein kinase 3 (DAP kinase 3) (EC 2.7.11.1) (DAP-like kinase) (Dlk) (MYPT1 kinase) (Zipper-interacting protein kinase) (ZIP-kinase)DAPK3 ZIPKO432934
Dehydrodolichyl diphosphate synthase (Dedol-PP synthase) (EC 2.5.1.-) (Cis-isoprenyltransferase) (CIT) (Cis-IPTase) (Epididymis tissue protein Li 189m)DHDDS HDSQ86SQ94
Dehydrogenase/reductase SDR family member 1 (EC 1.1.-.-)DHRS1Q96LJ74
Delta globin (Delta-globin chain) (Hemoglobin delta) (Hemoglobin, delta)HBD hCG_1641001A0N0714
Delta(24)-sterol reductase (EC 1.3.1.72) (24-dehydrocholesterol reductase) (3-beta-hydroxysterol delta-24-reductase) (Diminuto/dwarf1 homolog) (Seladin-1)DHCR24 KIAA0018Q153924
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