EVpedia provide top 100+ EV markers, selected according to their identification number.
Based on EV proteomes, we defined the identification number of protein A as the number of datasets which contain protein A.
Therefore, proteins with higher identification numbers were more conserved.

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Protein name Gene symbol UniProt accession Identification number
Exosome complex component RRP45 (Autoantigen PM/Scl 1) (Exosome component 9) (P75 polymyositis-scleroderma overlap syndrome-associated autoantigen) (Polymyositis/scleroderma autoantigen 1) (Polymyositis/scleroderma autoantigen 75 kDa) (PM/Scl-75)EXOSC9 PMSCL1Q062654
Eyes absent homolog 2 (EC 3.1.3.48)EYA2 EAB1O001674
F-box only protein 21FBXO21 FBX21 KIAA0875O949524
F-box-like/WD repeat-containing protein TBL1XR1 (Nuclear receptor corepressor/HDAC3 complex subunit TBLR1) (TBL1-related protein 1) (Transducin beta-like 1X-related protein 1)TBL1XR1 IRA1 TBLR1Q9BZK74
F-box/LRR-repeat protein 20 (F-box and leucine-rich repeat protein 20) (F-box/LRR-repeat protein 2-like)FBXL20 FBL2Q96IG24
FACT complex subunit SSRP1 (Chromatin-specific transcription elongation factor 80 kDa subunit) (Facilitates chromatin transcription complex 80 kDa subunit) (FACT 80 kDa subunit) (FACTp80) (Facilitates chromatin transcription complex subunit SSRP1) (Recombination signal sequence recognition protein 1) (Structure-specific recognition protein 1) (hSSRP1) (T160)SSRP1 FACT80Q089454
FAD-dependent oxidoreductase domain-containing protein 1 (EC 1.-.-.-)FOXRED1 FP634Q96CU94
Far upstream element-binding protein 1 (FBP) (FUSE-binding protein 1) (DNA helicase V) (hDH V)FUBP1Q96AE44
FARSLA protein (Phenylalanine-tRNA synthetase-like, alpha subunit, isoform CRA_b) (cDNA FLJ34774 fis, clone NT2NE2003309, highly similar to Phenylalanyl-tRNA synthetase alpha chain (EC 6.1.1.20))FARSLA hCG_172485Q6IBR24
FAS-associated factor 1 (hFAF1) (UBX domain-containing protein 12) (UBX domain-containing protein 3A)FAF1 UBXD12 UBXN3A CGI-03Q9UNN54
Fatty acid desaturase 2 (EC 1.14.19.-) (Delta(6) fatty acid desaturase) (D6D) (Delta(6) desaturase) (Delta-6 desaturase)FADS2O958644
FCH domain only protein 2FCHO2Q0JRZ94
FERM and PDZ domain-containing protein 2 (PDZ domain-containing protein 4) (PDZ domain-containing protein 5C)FRMPD2 PDZD5C PDZK4 PDZK5CQ68DX34
Ferrochelatase, mitochondrial (EC 4.99.1.1) (Heme synthase) (Protoheme ferro-lyase)FECHP228304
Fibroblast growth factor (FGF) (Fragment)FGF7 hCG_2001865Q6FGV54
Fibroblast growth factor 17 (FGF-17)FGF17 UNQ161/PRO187O602584
Fibroblast growth factor 19 (FGF-19)FGF19 UNQ334/PRO533O957504
Fibroblast growth factor receptor 2 (FGFR-2) (EC 2.7.10.1) (K-sam) (KGFR) (Keratinocyte growth factor receptor) (CD antigen CD332)FGFR2 BEK KGFR KSAMP218024
Fibroblast growth factor receptor 3 (FGFR-3) (EC 2.7.10.1) (CD antigen CD333)FGFR3 JTK4P226074
Fibronectin (FN) (Cold-insoluble globulin) (CIG) [Cleaved into: Anastellin; Ugl-Y1; Ugl-Y2; Ugl-Y3]FN1 FNP027514
Fibronectin type III and SPRY domain-containing protein 1 (MID1-related protein 1) (Microtubule-associated protein GLFND)FSD1 GLFND MIR1 VLP27Q9BTV54
FilaggrinFLGP209304
Flt3-interacting zinc finger protein 1 (Zinc finger protein 798)FIZ1 ZNF798Q96SL84
Fms-related tyrosine kinase 3 ligand (Flt3 ligand) (Flt3L) (SL cytokine)FLT3LGP497714
Folliculin-interacting protein 2 (FNIP1-like protein) (O6-methylguanine-induced apoptosis 1 protein)FNIP2 FNIPL KIAA1450 MAPO1Q9P2784
Forkhead box protein B1 (Transcription factor FKH-5)FOXB1 FKH5Q998534
Forkhead box protein D3 (HNF3/FH transcription factor genesis)FOXD3 HFH2Q9UJU54
Forkhead box protein O1 (Forkhead box protein O1A) (Forkhead in rhabdomyosarcoma)FOXO1 FKHR FOXO1AQ127784
Forkhead box protein P4 (Fork head-related protein-like A)FOXP4 FKHLAQ8IVH24
Forkhead box protein Q1 (HNF-3/forkhead-like protein 1) (HFH-1) (Hepatocyte nuclear factor 3 forkhead homolog 1)FOXQ1 HFH1Q9C0094
Formin-2FMN2Q9NZ564
Fragile histidine triad (Tumor suppressor protein) (Fragment)FHIT hCG_1997982Q45QG94
Fragile X mental retardation protein 1 (FMRP) (Protein FMR-1)FMR1Q067874
Frizzled-9 (Fz-9) (hFz9) (FzE6) (CD antigen CD349)FZD9 FZD3O001444
Fumarylacetoacetate hydrolase domain-containing protein 2A (EC 3.-.-.-)FAHD2A CGI-105Q96GK74
FUN14 domain-containing protein 1FUNDC1Q8IVP54
FUS protein (Fusion (Involved in t(1216) in malignant liposarcoma), isoform CRA_a) (Fusion, derived from t(12;16) malignant liposarcoma)FUS hCG_21147Q6IBQ54
FXYD domain-containing ion transport regulator 7FXYD7P585494
FYVE and coiled-coil domain-containing protein 1 (Zinc finger FYVE domain-containing protein 7)FYCO1 ZFYVE7Q9BQS84
G-protein coupled estrogen receptor 1 (Chemoattractant receptor-like 2) (Flow-induced endothelial G-protein coupled receptor 1) (FEG-1) (G protein-coupled estrogen receptor 1) (G-protein coupled receptor 30) (GPCR-Br) (IL8-related receptor DRY12) (Lymphocyte-derived G-protein coupled receptor) (LYGPR) (Membrane estrogen receptor) (mER)GPER1 CEPR CMKRL2 DRY12 GPER GPR30Q995274
G/T mismatch-specific thymine DNA glycosylase (cDNA FLJ50939, highly similar to G/T mismatch-specific thymine DNA glycosylase (EC 3.2.2.-))TDGB4E1274
G0/G1 switch protein 2 (G0/G1 switch regulatory protein 2) (Putative lymphocyte G0/G1 switch gene)G0S2P274694
G2/mitotic-specific cyclin-B1CCNB1 CCNBP146354
GA-binding protein subunit beta-1 (GABP subunit beta-1) (GABPB-1) (GABP subunit beta-2) (GABPB-2) (Nuclear respiratory factor 2) (Transcription factor E4TF1-47) (Transcription factor E4TF1-53)GABPB1 E4TF1B GABPB GABPB2Q065474
GABA(A) receptor-associated protein (GABARAP protein) (HCG1987397, isoform CRA_b)GABARAP hCG_1987397Q6IAW14
Gamma-glutamyltransferase light chain 1 (Gamma-glutamyltransferase-like activity 4) (Gamma-glutamyltransferase-like protein 6)GGTLC1 GGTLA4Q9BX514
Gamma-interferon-inducible lysosomal thiol reductase (EC 1.8.-.-) (Gamma-interferon-inducible protein IP-30) (Legumaturain)IFI30 GILT IP30P132844
Gap junction beta-3 protein (Connexin-31) (Cx31)GJB3 CX31O757124
Gap junction delta-3 protein (Connexin-31.9) (Cx31.9) (Gap junction alpha-11 protein) (Gap junction chi-1 protein)GJD3 GJA11 GJC1Q8N1444
Gastrin-releasing peptide (GRP) [Cleaved into: Neuromedin-C (GRP-10)]GRPP074924
GATA zinc finger domain-containing protein 1 (Ocular development-associated gene protein)GATAD1 ODAGQ8WUU54
GemininGMNNO754964
General transcription factor IIH subunit 1 (Basic transcription factor 2 62 kDa subunit) (BTF2 p62) (General transcription factor IIH polypeptide 1) (TFIIH basal transcription factor complex p62 subunit)GTF2H1 BTF2P327804
Genetic suppressor element 1GSE1 KIAA0182Q146874
Germ cell-less homolog 1 (Drosophila) (Putative uncharacterized protein FLJ13057)FLJ13057 GMCL1 hCG_40576Q53SE74
Glutathione S-transferase A4 (EC 2.5.1.18) (GST class-alpha member 4) (Glutathione S-transferase A4-4)GSTA4O152174
Glutathione S-transferase kappa 1 (EC 2.5.1.18) (GST 13-13) (GST class-kappa) (GSTK1-1) (hGSTK1) (Glutathione S-transferase subunit 13)GSTK1 HDCMD47PQ9Y2Q34
Glycerate kinase (EC 2.7.1.31) (HBeAg-binding protein 4)GLYCTK HBEBP4 LP5910Q8IVS84
Glycoprotein hormone alpha-2 (Putative secreted protein Zsig51) (Thyrostimulin subunit alpha)GPHA2 GPA2 ZSIG51Q96T914
Glycylpeptide N-tetradecanoyltransferase 1 (EC 2.3.1.97) (Myristoyl-CoA:protein N-myristoyltransferase 1) (NMT 1) (Type I N-myristoyltransferase) (Peptide N-myristoyltransferase 1)NMT1 NMTP304194
Glypican-2 [Cleaved into: Secreted glypican-2]GPC2Q8N1584
Golgi phosphoprotein 3-like (GPP34-related protein)GOLPH3L GPP34RQ9H4A54
Golgi to ER traffic protein 4 homolog (Conserved edge-expressed protein) (Transmembrane domain recognition complex 35 kDa subunit) (TRC35)GET4 C7orf20 CEE TRC35 CGI-20Q7L5D64
Golgin subfamily A member 5 (Cell proliferation-inducing gene 31 protein) (Golgin-84) (Protein Ret-II) (RET-fused gene 5 protein)GOLGA5 RETII RFG5 PIG31Q8TBA64
Golgin subfamily B member 1 (372 kDa Golgi complex-associated protein) (GCP372) (Giantin) (Macrogolgin)GOLGB1Q147894
GON-4-like protein (GON-4 homolog)GON4L GON4 KIAA1606Q3T8J94
GPN-loop GTPase 1 (MBD2-interacting protein) (MBDin) (XPA-binding protein 1)GPN1 MBDIN XAB1 HUSSY-23Q9HCN44
GrancalcinGCA GCLP286764
Graves disease carrier protein (GDC) (Graves disease autoantigen) (GDA) (Mitochondrial solute carrier protein homolog) (Solute carrier family 25 member 16)SLC25A16 GDAP162604
GRB2-related adapter proteinGRAPQ135884
GRIP1-associated protein 1 (GRASP-1)GRIPAP1 KIAA1167Q4V3284
Group IID secretory phospholipase A2 (GIID sPLA2) (sPLA2-IID) (EC 3.1.1.4) (PLA2IID) (Phosphatidylcholine 2-acylhydrolase 2D) (Secretory-type PLA, stroma-associated homolog)PLA2G2D SPLASHQ9UNK44
Growth hormone variant (GH-V) (Growth hormone 2) (Placenta-specific growth hormone)GH2P012424
GrpE protein homolog 2, mitochondrial (Mt-GrpE#2)GRPEL2Q8TAA54
GTPase NRas (Transforming protein N-Ras)NRAS HRAS1P011114
Guanine nucleotide binding protein (G protein), alpha z polypeptideGNAZQ8N6524
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 (G protein subunit beta-2) (Transducin beta chain 2)GNB2P628794
Guanylate cyclase activator 2B [Cleaved into: Guanylate cyclase C-activating peptide 2 (Guanylate cyclase C-activating peptide II) (GCAP-II); Uroguanylin (UGN)]GUCA2BQ166614
Guanylate cyclase soluble subunit alpha-3 (GCS-alpha-3) (EC 4.6.1.2) (GCS-alpha-1) (Soluble guanylate cyclase large subunit)GUCY1A3 GUC1A3 GUCSA3 GUCY1A1Q021084
GUK1 protein (Guanylate kinase 1, isoform CRA_a)GUK1 hCG_1984660Q6IBG84
HAUS augmin-like complex subunit 7 (26S proteasome-associated UCH37-interacting protein 1) (UCHL5-interacting protein) (X-linked protein STS1769)HAUS7 UCHL5IP UIP1Q998714
HCG1994130, isoform CRA_a (cDNA FLJ30359 fis, clone BRACE2007760, highly similar to 40S RIBOSOMAL PROTEIN S15A) (cDNA, FLJ92249, Homo sapiens ribosomal protein S15a (RPS15A), mRNA)hCG_1994130B2R4W84
Heart- and neural crest derivatives-expressed protein 1 (Class A basic helix-loop-helix protein 27) (bHLHa27) (Extraembryonic tissues, heart, autonomic nervous system and neural crest derivatives-expressed protein 1) (eHAND)HAND1 BHLHA27 EHANDO960044
HEAT repeat-containing protein 2HEATR2Q86Y564
Heat shock 70 kDa protein 12AHSPA12A KIAA0417O433014
Heat shock protein beta-6 (HspB6) (Heat shock 20 kDa-like protein p20)HSPB6O145584
Heat shock protein beta-7 (HspB7) (Cardiovascular heat shock protein) (cvHsp)HSPB7 CVHSPQ9UBY94
Hepatocyte growth factor receptor (HGF receptor) (EC 2.7.10.1) (HGF/SF receptor) (Proto-oncogene c-Met) (Scatter factor receptor) (SF receptor) (Tyrosine-protein kinase Met)METP085814
Hepatocyte nuclear factor 6 (HNF-6) (One cut domain family member 1) (One cut homeobox 1)ONECUT1 HNF6 HNF6AQ9UBC04
Hepatoma-derived growth factor-like protein 1 (PWWP domain-containing protein 1)HDGFL1 PWWP1Q5TGJ64
Hereditary hemochromatosis protein (HLA-H)HFE HLAHQ302014
Hermansky-Pudlak syndrome 3 proteinHPS3Q969F94
Heterogeneous nuclear ribonucleoprotein H2 (hnRNP H2) (FTP-3) (Heterogeneous nuclear ribonucleoprotein H') (hnRNP H') [Cleaved into: Heterogeneous nuclear ribonucleoprotein H2, N-terminally processed]HNRNPH2 FTP3 HNRPH2P557954
High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A (EC 3.1.4.17)PDE8AO606584
High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A (EC 3.1.4.35)PDE9AO760834
High affinity immunoglobulin epsilon receptor subunit gamma (Fc receptor gamma-chain) (FcRgamma) (Fc-epsilon RI-gamma) (IgE Fc receptor subunit gamma) (FceRI gamma)FCER1GP302734
High mobility group nucleosome-binding domain-containing protein 3 (Thyroid receptor-interacting protein 7) (TR-interacting protein 7) (TRIP-7)HMGN3 TRIP7 PNAS-24Q156514
Histone acetyltransferase KAT2A (EC 2.3.1.48) (General control of amino acid synthesis protein 5-like 2) (Histone acetyltransferase GCN5) (HsGCN5) (Lysine acetyltransferase 2A) (STAF97)KAT2A GCN5 GCN5L2 HGCN5Q928304
Histone deacetylase (EC 3.5.1.98)HDAC1 hCG_41610Q6IT964
Histone H2A type 1-J (Histone H2A/e)HIST1H2AJ H2AFEQ998784
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