EVpedia provide top 100+ EV markers, selected according to their identification number.
Based on EV proteomes, we defined the identification number of protein A as the number of datasets which contain protein A.
Therefore, proteins with higher identification numbers were more conserved.

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Protein name Gene symbol UniProt accession Identification number
Kinesin-associated protein 3 (KAP-3) (KAP3) (Smg GDS-associated protein)KIFAP3 KIF3AP SMAPQ928454
Kinesin-like protein KIF14KIF14 KIAA0042Q150584
Kinesin-like protein KIF20B (Cancer/testis antigen 90) (CT90) (Kinesin-related motor interacting with PIN1) (M-phase phosphoprotein 1) (MPP1)KIF20B KRMP1 MPHOSPH1Q96Q894
Kinesin-like protein KIF23 (Kinesin-like protein 5) (Mitotic kinesin-like protein 1)KIF23 KNSL5 MKLP1Q022414
Kininogen-1 (Alpha-2-thiol proteinase inhibitor) (Fitzgerald factor) (High molecular weight kininogen) (HMWK) (Williams-Fitzgerald-Flaujeac factor) [Cleaved into: Kininogen-1 heavy chain; T-kinin (Ile-Ser-Bradykinin); Bradykinin (Kallidin I); Lysyl-bradykinin (Kallidin II); Kininogen-1 light chain; Low molecular weight growth-promoting factor]KNG1 BDK KNGP010424
Krev interaction trapped protein 1 (Krev interaction trapped 1) (Cerebral cavernous malformations 1 protein)KRIT1 CCM1O005224
Krueppel-like factor 5 (Basic transcription element-binding protein 2) (BTE-binding protein 2) (Colon krueppel-like factor) (GC-box-binding protein 2) (Intestinal-enriched krueppel-like factor) (Transcription factor BTEB2)KLF5 BTEB2 CKLF IKLFQ138874
Krueppel-like factor 8 (Basic krueppel-like factor 3) (Zinc finger protein 741)KLF8 BKLF3 ZNF741O956004
Krueppel-like factor 9 (Basic transcription element-binding protein 1) (BTE-binding protein 1) (GC-box-binding protein 1) (Transcription factor BTEB1)KLF9 BTEB BTEB1Q138864
Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial (KAT/AadAT) (2-aminoadipate aminotransferase) (2-aminoadipate transaminase) (EC 2.6.1.39) (Alpha-aminoadipate aminotransferase) (AadAT) (Kynurenine aminotransferase II) (Kynurenine--oxoglutarate aminotransferase II) (Kynurenine--oxoglutarate transaminase 2) (EC 2.6.1.7) (Kynurenine--oxoglutarate transaminase II)AADAT KAT2Q8N5Z04
L-aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase (EC 2.7.8.-) (4'-phosphopantetheinyl transferase) (Alpha-aminoadipic semialdehyde dehydrogenase-phosphopantetheinyl transferase) (AASD-PPT) (LYS5 ortholog)AASDHPPT CGI-80 HAH-P HSPC223 x0005Q9NRN74
L-dopachrome tautomerase (DCT) (DT) (EC 5.3.3.12) (L-dopachrome Delta-isomerase) (Tyrosinase-related protein 2) (TRP-2) (TRP2)DCT TYRP2P401264
L-lactate dehydrogenase (EC 1.1.1.27)LDHB hCG_24788Q5U0774
Lamin-B2LMNB2 LMN2Q032524
Large neutral amino acids transporter small subunit 2 (L-type amino acid transporter 2) (hLAT2) (Solute carrier family 7 member 8)SLC7A8 LAT2Q9UHI54
Large neutral amino acids transporter small subunit 3 (L-type amino acid transporter 3) (Prostate cancer overexpressed gene 1 protein) (Solute carrier family 43 member 1)SLC43A1 LAT3 PB39 POV1O753874
Late cornified envelope protein 2D (Late envelope protein 12) (Small proline-rich-like epidermal differentiation complex protein 1A)LCE2D LEP12 SPRL1AQ5TA824
Late cornified envelope protein 3A (Late envelope protein 13)LCE3A LEP13Q5TA764
Latent-transforming growth factor beta-binding protein 3 (LTBP-3)LTBP3Q9NS154
Latent-transforming growth factor beta-binding protein 4 (LTBP-4)LTBP4Q8N2S14
Left-right determination factor 2 (Endometrial bleeding-associated factor) (Left-right determination factor A) (Protein lefty-2) (Protein lefty-A) (Transforming growth factor beta-4) (TGF-beta-4)LEFTY2 EBAF LEFTA LEFTYA TGFB4 PSEC0024O002924
Leptin (Obesity factor)LEP hCG_33000 tcag7.84A4D0Y84
Leptin receptor overlapping transcript-like 1 (Endospanin-2)LEPROTL1 My047 UNQ577/PRO1139O952144
Lethal(2) giant larvae protein homolog 2 (HGL)LLGL2Q6P1M34
Leucine carboxyl methyltransferase 2 (EC 2.1.1.-) (p21WAF1/CIP1 promoter-interacting protein) (tRNA wybutosine-synthesizing protein 4 homolog) (tRNA yW-synthesizing protein 4 homolog)LCMT2 KIAA0547 TYW4O602944
Leucine zipper transcription factor-like protein 1LZTFL1Q9NQ484
Leucine-rich repeat and calponin homology domain-containing protein 3LRCH3Q96II84
Leucine-rich repeat and calponin homology domain-containing protein 4 (Leucine-rich repeat neuronal protein 4) (Leucine-rich neuronal protein)LRCH4 LRN LRRN1 LRRN4O754274
Leucine-rich repeat-containing G-protein coupled receptor 4 (G-protein coupled receptor 48)LGR4 GPR48Q9BXB14
Leucine-rich repeat-containing protein 14LRRC14 KIAA0014Q150484
Leucine-rich repeat-containing protein 28LRRC28 UNQ436/PRO867Q86X404
Leucine-rich repeat-containing protein 37B (C66 SLIT-like testicular protein)LRRC37BQ96QE44
Leucine-rich repeat-containing protein 48LRRC48Q9H0694
Leucyl-cystinyl aminopeptidase (Cystinyl aminopeptidase) (EC 3.4.11.3) (Insulin-regulated membrane aminopeptidase) (Insulin-responsive aminopeptidase) (IRAP) (Oxytocinase) (OTase) (Placental leucine aminopeptidase) (P-LAP) [Cleaved into: Leucyl-cystinyl aminopeptidase, pregnancy serum form]LNPEP OTASEQ9UIQ64
Leukemia-associated protein 7 (Deleted in lymphocytic leukemia 7)DLEU7 LEU7Q6UYE14
Leukocyte immunoglobulin-like receptor subfamily A member 3 (CD85 antigen-like family member E) (Immunoglobulin-like transcript 6) (ILT-6) (Leukocyte immunoglobulin-like receptor 4) (LIR-4) (Monocyte inhibitory receptor HM43/HM31) (CD antigen CD85e)LILRA3 ILT6 LIR4Q8N6C84
Leukocyte immunoglobulin-like receptor subfamily A member 6 (Immunoglobulin-like transcript 8) (ILT-8) (Leukocyte Ig-like receptor)LILRA6 ILT8Q6PI734
Leukocyte-associated immunoglobulin-like receptor 2 (LAIR-2) (CD antigen CD306)LAIR2 CD306Q6ISS44
Leukotriene C4 synthase (LTC4 synthase) (EC 4.4.1.20) (Leukotriene-C(4) synthase)LTC4SQ168734
Ligand-dependent corepressor (LCoR) (Mblk1-related protein 2)LCOR KIAA1795 MLR2Q96JN04
LIM/homeobox protein Lhx1 (LIM homeobox protein 1) (Homeobox protein Lim-1) (hLim-1)LHX1 LIM-1 LIM1P487424
LIM/homeobox protein Lhx9 (LIM homeobox protein 9)LHX9Q9NQ694
Lipid phosphate phosphohydrolase 2 (EC 3.1.3.4) (PAP2-gamma) (PAP2-G) (Phosphatidate phosphohydrolase type 2c) (Phosphatidic acid phosphatase 2c) (PAP-2c) (PAP2c)PPAP2C LPP2O436884
Lipoyl synthase, mitochondrial (EC 2.8.1.8) (Lipoate synthase) (LS) (Lip-syn) (Lipoic acid synthase)LIAS LAS HUSSY-01O437664
Liver carboxylesterase 1 (Acyl-coenzyme A:cholesterol acyltransferase) (ACAT) (Brain carboxylesterase hBr1) (Carboxylesterase 1) (CE-1) (hCE-1) (EC 3.1.1.1) (Cocaine carboxylesterase) (Egasyn) (HMSE) (Methylumbelliferyl-acetate deacetylase 1) (EC 3.1.1.56) (Monocyte/macrophage serine esterase) (Retinyl ester hydrolase) (REH) (Serine esterase 1) (Triacylglycerol hydrolase) (TGH)CES1 CES2 SES1P231414
LON peptidase N-terminal domain and RING finger protein 1 (RING finger protein 191)LONRF1 RNF191Q17RB84
Long-chain fatty acid transport protein 1 (FATP-1) (Fatty acid transport protein 1) (EC 6.2.1.-) (Solute carrier family 27 member 1)SLC27A1 ACSVL5 FATP1Q6PCB74
LoricrinLOR LRNP234904
Low density lipoprotein-related protein 1 variant (Fragment)0Q59FG24
Low-density lipoprotein receptor-related protein 3 (LRP-3) (105 kDa low-density lipoprotein receptor-related protein) (hLRp105)LRP3O750744
Low-density lipoprotein receptor-related protein 6 (LRP-6)LRP6O755814
Low-density lipoprotein receptor-related protein 8 (LRP-8) (Apolipoprotein E receptor 2)LRP8 APOER2Q141144
LUC7-like (S. cerevisiae) (LUC7-like (S. cerevisiae), isoform CRA_g) (Putative RNA-binding protein Luc7-like 1)LUC7L hCG_22425 LA16c-OS12.1-001Q1W6G44
Ly6/PLAUR domain-containing protein 6BLYPD6BQ8NI324
Lymphocyte antigen 6 complex locus protein G5bLY6G5B C6orf19 G5BQ8NDX94
Lymphoid enhancer-binding factor 1 (LEF-1) (T cell-specific transcription factor 1-alpha) (TCF1-alpha)LEF1Q9UJU24
LYN protein (Fragment)LYNQ6NUK74
LYR motif-containing protein 4LYRM4 C6orf149 ISD11 CGI-203Q9HD344
Lysine-specific demethylase 3A (EC 1.14.11.-) (JmjC domain-containing histone demethylation protein 2A) (Jumonji domain-containing protein 1A)KDM3A JHDM2A JMJD1 JMJD1A KIAA0742 TSGAQ9Y4C14
Lysine-specific demethylase 3B (EC 1.14.11.-) (JmjC domain-containing histone demethylation protein 2B) (Jumonji domain-containing protein 1B) (Nuclear protein 5qNCA)KDM3B C5orf7 JHDM2B JMJD1B KIAA1082Q7LBC64
Lysine-specific demethylase 4B (EC 1.14.11.-) (JmjC domain-containing histone demethylation protein 3B) (Jumonji domain-containing protein 2B)KDM4B JHDM3B JMJD2B KIAA0876O949534
Lysine-specific demethylase 5A (EC 1.14.11.-) (Histone demethylase JARID1A) (Jumonji/ARID domain-containing protein 1A) (Retinoblastoma-binding protein 2) (RBBP-2)KDM5A JARID1A RBBP2 RBP2P293754
Lysophospholipid acyltransferase LPCAT4 (1-acylglycerol-3-phosphate O-acyltransferase 7) (1-AGP acyltransferase 7) (1-AGPAT 7) (1-acylglycerophosphocholine O-acyltransferase) (EC 2.3.1.23) (1-acylglycerophosphoserine O-acyltransferase) (EC 2.3.1.n6) (1-alkenylglycerophosphoethanolamine O-acyltransferase) (EC 2.3.1.121) (1-alkylglycerophosphocholine O-acetyltransferase) (EC 2.3.1.67) (Acyltransferase-like 3) (Lysophosphatidylcholine acyltransferase 4) (Lysophosphatidylethanolamine acyltransferase 2) (EC 2.3.1.n7) (Plasmalogen synthase)LPCAT4 AGPAT7 AYTL3 LPEAT2Q643R34
Lysosomal-associated transmembrane protein 4A (Golgi 4-transmembrane-spanning transporter MTP)LAPTM4A KIAA0108 LAPTM4 MBNT MTRP UNQ1846/PRO3574Q150124
Lysosomal-trafficking regulator (Beige homolog)LYST CHS CHS1Q996984
M-phase phosphoprotein 6MPHOSPH6 MPP6Q995474
M-phase-specific PLK1-interacting protein (TTD non-photosensitive 1 protein)MPLKIP C7orf11 TTDN1Q8TAP94
Macrophage migration inhibitory factor (Fragment)0I4AY874
Macrophage scavenger receptor types I and II (Macrophage acetylated LDL receptor I and II) (Scavenger receptor class A member 1) (CD antigen CD204)MSR1 SCARA1P217574
Magnesium transporter NIPA3 (NIPA-like protein 1) (Non-imprinted in Prader-Willi/Angelman syndrome region protein 3)NIPAL1 NIPA3 NPAL1Q6NVV34
Magnesium transporter protein 1 (MagT1) (Implantation-associated protein) (IAP)MAGT1 IAG2 PSEC0084 UNQ628/PRO1244Q9H0U34
MAGUK p55 subfamily member 4 (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 5 protein) (Discs large homolog 6)MPP4 ALS2CR5 DLG6Q96JB84
Major facilitator superfamily domain-containing protein 12MFSD12 C19orf28Q6NUT34
Mannosyl-oligosaccharide 1,2-alpha-mannosidase IB (EC 3.2.1.113) (Mannosidase alpha class 1A member 2) (Processing alpha-1,2-mannosidase IB) (Alpha-1,2-mannosidase IB)MAN1A2 MAN1BO604764
Mannosyl-oligosaccharide glucosidase (EC 3.2.1.106) (Processing A-glucosidase I)MOGS GCS1Q137244
MAP kinase-activating death domain protein (Differentially expressed in normal and neoplastic cells) (Insulinoma glucagonoma clone 20) (Rab3 GDP/GTP exchange factor)MADD DENN IG20 KIAA0358Q8WXG64
MAP/microtubule affinity-regulating kinase 3 (EC 2.7.11.1) (C-TAK1) (cTAK1) (Cdc25C-associated protein kinase 1) (ELKL motif kinase 2) (EMK-2) (Protein kinase STK10) (Ser/Thr protein kinase PAR-1) (Par-1a) (Serine/threonine-protein kinase p78)MARK3 CTAK1 EMK2P274484
MAPK/MAK/MRK overlapping kinase (EC 2.7.11.22) (MOK protein kinase) (Renal tumor antigen 1) (RAGE-1)MOK RAGE RAGE1Q9UQ074
Max dimerization protein 1 (Max dimerizer 1) (Protein MAD)MXD1 MADQ051954
MBT domain-containing protein 1MBTD1Q05BQ54
Mediator of RNA polymerase II transcription subunit 13 (Activator-recruited cofactor 250 kDa component) (ARC250) (Mediator complex subunit 13) (Thyroid hormone receptor-associated protein 1) (Thyroid hormone receptor-associated protein complex 240 kDa component) (Trap240) (Vitamin D3 receptor-interacting protein complex component DRIP250) (DRIP250)MED13 ARC250 KIAA0593 THRAP1 TRAP240Q9UHV74
Mediator of RNA polymerase II transcription subunit 14 (Activator-recruited cofactor 150 kDa component) (ARC150) (Cofactor required for Sp1 transcriptional activation subunit 2) (CRSP complex subunit 2) (Mediator complex subunit 14) (RGR1 homolog) (hRGR1) (Thyroid hormone receptor-associated protein complex 170 kDa component) (Trap170) (Transcriptional coactivator CRSP150) (Vitamin D3 receptor-interacting protein complex 150 kDa component) (DRIP150)MED14 ARC150 CRSP2 CXorf4 DRIP150 EXLM1 RGR1 TRAP170O602444
Mediator of RNA polymerase II transcription subunit 20 (Mediator complex subunit 20) (TRF-proximal protein homolog) (hTRFP)MED20 TRFPQ9H9444
Mediator of RNA polymerase II transcription subunit 21 (Mediator complex subunit 21) (RNA polymerase II holoenzyme component SRB7) (RNAPII complex component SRB7) (hSrb7)MED21 SRB7 SURB7Q135034
Mediator of RNA polymerase II transcription subunit 22 (Mediator complex subunit 22) (Surfeit locus protein 5) (Surf-5)MED22 SURF5Q155284
Mediator of RNA polymerase II transcription subunit 30 (Mediator complex subunit 30) (TRAP/Mediator complex component TRAP25) (Thyroid hormone receptor-associated protein 6) (Thyroid hormone receptor-associated protein complex 25 kDa component) (Trap25)MED30 THRAP6 TRAP25Q96HR34
Mediator of RNA polymerase II transcription subunit 4 (Activator-recruited cofactor 36 kDa component) (ARC36) (Mediator complex subunit 4) (TRAP/SMCC/PC2 subunit p36 subunit) (Vitamin D3 receptor-interacting protein complex 36 kDa component) (DRIP36)MED4 ARC36 DRIP36 VDRIP HSPC126Q9NPJ64
Meiotic recombination protein DMC1/LIM15 homologDMC1 DMC1H LIM15Q145654
Melanoma-associated antigen 1 (Antigen MZ2-E) (Cancer/testis antigen 1.1) (CT1.1) (MAGE-1 antigen)MAGEA1 MAGE1 MAGE1AP433554
Melanoma-derived growth regulatory protein (Melanoma inhibitory activity protein)MIAQ166744
Membralin (Transmembrane protein 259)TMEM259 C19orf6Q4ZIN34
Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 3 (Membrane-associated guanylate kinase inverted 3) (MAGI-3)MAGI3 KIAA1634Q5TCQ94
Membrane-associated phosphatidylinositol transfer protein 1 (Drosophila retinal degeneration B homolog) (Phosphatidylinositol transfer protein, membrane-associated 1) (PITPnm 1) (Pyk2 N-terminal domain-interacting receptor 2) (NIR-2)PITPNM1 DRES9 NIR2 PITPNMO005624
Merlin (Moesin-ezrin-radixin-like protein) (Neurofibromin-2) (Schwannomerlin) (Schwannomin)NF2 SCHP352404
Mesoderm development candidate 1MESDC1Q9H1K64
Mesoderm induction early response protein 1 (Early response 1) (Er1) (Mi-er1) (hMi-er1)MIER1 KIAA1610Q8N1084
Metabotropic glutamate receptor 4 (mGluR4)GRM4 GPRC1D MGLUR4Q148334
Metal transporter CNNM1 (Ancient conserved domain-containing protein 1) (Cyclin-M1)CNNM1 ACDP1Q9NRU34
Metallothionein-1M (MT-1M) (Metallothionein-IM) (MT-IM)MT1M MT1KQ8N3394
MeteorinMETRN C16orf23 RJD6Q9UJH84
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