EVpedia provide top 100+ EV markers, selected according to their identification number.
Based on EV proteomes, we defined the identification number of protein A as the number of datasets which contain protein A.
Therefore, proteins with higher identification numbers were more conserved.

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Protein name Gene symbol UniProt accession Identification number
Protein TEX261TEX261 UNQ1882/PRO4325Q6UWH64
Protein transport protein Sec23A (SEC23-related protein A)SEC23AQ154364
Protein unc-50 homolog (Periodontal ligament-specific protein 22) (PDLs22) (Protein GMH1 homolog) (hGMH1) (Uncoordinated-like protein)UNC50 UNCL HSD-23 HSD23Q53HI14
Protein virilizer homologKIAA1429 MSTP054Q69YN44
Protein YIPF3 (Killer lineage protein 1) (Natural killer cell-specific antigen KLIP1) (YIP1 family member 3) [Cleaved into: Protein YIPF3, 36 kDa form III]YIPF3 C6orf109 KLIP1Q9GZM54
Protein yippee-like 3YPEL3 FKSG5P612364
Protein zer-1 homolog (Hzyg) (Zyg-11 homolog B-like protein)ZER1 C9orf60 ZYG ZYG11BLQ7Z7L74
Protein zyg-11 homolog BZYG11B KIAA1730Q9C0D34
Protein-L-isoaspartate O-methyltransferase domain-containing protein 1PCMTD1Q96MG84
Protocadherin-7 (Brain-heart protocadherin) (BH-Pcdh)PCDH7 BHPCDHO602454
Protoporphyrinogen oxidase (PPO) (EC 1.3.3.4)PPOXP503364
PRP31 pre-mRNA processing factor 31 homolog (Yeast), isoform CRA_a (U4/U6 small nuclear ribonucleoprotein Prp31)PRPF31 hCG_20945F1T0A54
Pulmonary surfactant-associated protein A2 (PSP-A) (PSPA) (SP-A) (SP-A2) (35 kDa pulmonary surfactant-associated protein) (Alveolar proteinosis protein) (Collectin-5)SFTPA2 COLEC5 PSAP SFTP1 SFTPA SFTPA2BQ8IWL14
Purine nucleoside phosphorylase (PNP) (EC 2.4.2.1) (Inosine phosphorylase) (Inosine-guanosine phosphorylase)PNP NPP004914
Putative interleukin-17 receptor E-like (IL-17 receptor E-like) (IL-17RE-like)IL17RELQ6ZVW74
Putative monooxygenase p33MONOX (EC 1.-.-.-) (Brain-derived rescue factor p60MONOX) (Flavin monooxygenase motif-containing protein of 33 kDa)KIAA1191 P33MONOXQ96A734
Putative peptidyl-tRNA hydrolase PTRHD1 (EC 3.1.1.29) (Peptidyl-tRNA hydrolase domain-containing protein 1)PTRHD1 C2orf79Q6GMV34
Putative phospholipase B-like 2 (EC 3.1.1.-) (76 kDa protein) (p76) (LAMA-like protein 2) (Lamina ancestor homolog 2) (Phospholipase B domain-containing protein 2) [Cleaved into: Putative phospholipase B-like 2 32 kDa form; Putative phospholipase B-like 2 45 kDa form]PLBD2Q8NHP84
Putative protein GATS (STAG3 opposite strand transcript protein)GATS STAG3OSQ8NAP14
Putative transferase CAF17, mitochondrial (EC 2.1.-.-) (Iron-sulfur cluster assembly factor homolog)IBA57 C1orf69Q5T4404
Putative uncharacterized protein C11orf45C11orf45Q8TAV54
Putative uncharacterized protein C11orf80C11orf80Q8N6T04
Putative uncharacterized protein C18orf56C18orf56Q8TAI14
Putative uncharacterized protein C1orf210C1orf210Q8IVY14
Putative uncharacterized protein DKFZp451J152DKFZp451J152Q86TD34
Putative uncharacterized protein DKFZp686H01244DKFZp686H01244Q7Z3M24
Putative uncharacterized protein DKFZp686J11229 (Fragment)DKFZp686J11229Q6MZF94
Pyruvate carboxylase, mitochondrial (EC 6.4.1.1) (Pyruvic carboxylase) (PCB)PCP114984
Pyruvate dehydrogenase phosphatase regulatory subunit, mitochondrial (PDPr)PDPR KIAA1990Q8NCN54
Quinone oxidoreductase (EC 1.6.5.5) (NADPH:quinone reductase) (Zeta-crystallin)CRYZQ082574
Quinone oxidoreductase PIG3 (EC 1.-.-.-) (Tumor protein p53-inducible protein 3) (p53-induced gene 3 protein)TP53I3 PIG3Q53FA74
Rab GDP dissociation inhibitor alpha (Rab GDI alpha) (Guanosine diphosphate dissociation inhibitor 1) (GDI-1) (Oligophrenin-2) (Protein XAP-4)GDI1 GDIL OPHN2 RABGDIA XAP4P311504
Rab GTPase-activating protein 1 (GAP and centrosome-associated protein) (Rab6 GTPase-activating protein GAPCenA)RABGAP1 HSPC094Q9Y3P94
Rab GTPase-activating protein 1-like, isoform 10RABGAP1L HHL KIAA0471B7ZAP04
Rab GTPase-binding effector protein 2 (Rabaptin-5beta)RABEP2 RABPT5BQ9H5N14
Rab11 family-interacting protein 1 (Rab11-FIP1) (Rab-coupling protein)RAB11FIP1 RCPQ6WKZ44
Rab9 effector protein with kelch motifs (40 kDa Rab9 effector protein) (p40)RABEPK RAB9P40Q7Z6M14
Rac GTPase-activating protein 1 (Male germ cell RacGap) (MgcRacGAP) (Protein CYK4 homolog) (CYK4) (HsCYK-4)RACGAP1 KIAA1478 MGCRACGAPQ9H0H54
Radial spoke head 10 homolog B2RSPH10B2B2RC854
Radiated keratinocyte mRNA 266 (keratin-related protein) (Fragment)0Q146664
RAF proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (Proto-oncogene c-RAF) (cRaf) (Raf-1)RAF1 RAFP040494
RalBP1-associated Eps domain-containing protein 2 (Partner of RalBP1) (RalBP1-interacting protein 2)REPS2 POB1Q8NFH84
Ran-binding protein 3-likeRANBP3LQ86VV44
Rap guanine nucleotide exchange factor 2 (Cyclic nucleotide ras GEF) (CNrasGEF) (Neural RAP guanine nucleotide exchange protein) (nRap GEP) (PDZ domain-containing guanine nucleotide exchange factor 1) (PDZ-GEF1) (RA-GEF-1) (Ras/Rap1-associating GEF-1)RAPGEF2 KIAA0313 NRAPGEP PDZGEF1Q9Y4G84
Rap1 GTPase-activating protein 1 (Rap1GAP) (Rap1GAP1)RAP1GAP KIAA0474 RAP1GA1P477364
Rapamycin-insensitive companion of mTOR (AVO3 homolog) (hAVO3)RICTOR KIAA1999Q6R3274
Ras association domain-containing protein 6RASSF6Q6ZTQ34
Ras GTPase-activating protein 4 (Calcium-promoted Ras inactivator) (Ras p21 protein activator 4) (RasGAP-activating-like protein 2)RASA4 CAPRI GAPL KIAA0538O433744
Ras-related GTP-binding protein A (Rag A) (RagA) (Adenovirus E3 14.7 kDa-interacting protein 1) (FIP-1)RRAGAQ7L5234
Ras-related protein Rab-14RAB14P611064
Ras-related protein Rab-31 (Ras-related protein Rab-22B)RAB31 RAB22BQ136364
Ras-related protein Rab-3ARAB3AP203364
Ras-related protein Rab-4BRAB4B PP1596P610184
Ras-related protein Rab-8BRAB8BQ929304
Ras-responsive element-binding protein 1 (RREB-1) (Finger protein in nuclear bodies) (Raf-responsive zinc finger protein LZ321) (Zinc finger motif enhancer-binding protein 1) (Zep-1)RREB1 FINBQ927664
RBM15 protein (Fragment)RBM15Q86VW94
RE1-silencing transcription factor (Neural-restrictive silencer factor) (X2 box repressor)REST NRSF XBRQ131274
Receptor-binding cancer antigen expressed on SiSo cells (Cancer-associated surface antigen RCAS1) (Estrogen receptor-binding fragment-associated gene 9 protein)EBAG9 RCAS1O005594
Receptor-type tyrosine-protein phosphatase C (EC 3.1.3.48) (Leukocyte common antigen) (L-CA) (T200) (CD antigen CD45)PTPRC CD45P085754
RecQ-mediated genome instability protein 1 (BLM-associated protein of 75 kDa) (BLAP75) (FAAP75)RMI1 C9orf76Q9H9A74
Regulating synaptic membrane exocytosis protein 2 (Rab-3-interacting molecule 2) (RIM 2) (Rab-3-interacting protein 3)RIMS2 KIAA0751 RAB3IP3 RIM2Q9UQ264
Regulation of nuclear pre-mRNA domain-containing protein 1B (Cell cycle-related and expression-elevated protein in tumor)RPRD1B C20orf77 CREPTQ9NQG54
Regulator of G-protein signaling 2 (RGS2) (Cell growth-inhibiting gene 31 protein) (G0/G1 switch regulatory protein 8)RGS2 G0S8 GIG31P412204
Regulator of nonsense transcripts 3B (Nonsense mRNA reducing factor 3B) (Up-frameshift suppressor 3 homolog B) (hUpf3B) (Up-frameshift suppressor 3 homolog on chromosome X) (hUpf3p-X)UPF3B RENT3B UPF3XQ9BZI74
RELT-like protein 2RELL2 C5orf16 UNQ9423/PRO34565Q8NC244
Renalase (EC 1.4.-.-) (Monoamine oxidase-C) (MAO-C)RNLS C10orf59Q5VYX04
Replication factor C subunit 4 (Activator 1 37 kDa subunit) (A1 37 kDa subunit) (Activator 1 subunit 4) (Replication factor C 37 kDa subunit) (RF-C 37 kDa subunit) (RFC37)RFC4P352494
Replication protein A 14 kDa subunit (RP-A p14) (Replication factor A protein 3) (RF-A protein 3)RPA3 REPA3 RPA14P352444
Repressor of RNA polymerase III transcription MAF1 homologMAF1Q9H0634
Reticulon-4 receptor-like 2 (Nogo receptor-like 3) (Nogo-66 receptor homolog 1) (Nogo-66 receptor-related protein 2) (NgR2)RTN4RL2 NGRH1 NGRL3Q86UN34
Retinoic acid nuclear receptor gamma variant 1 (Retinoic acid receptor gamma) (Retinoic acid receptor, gamma, isoform CRA_b) (cDNA FLJ75202, highly similar to Homo sapiens, retinoic acid receptor, gamma)NR1B3 RARG hCG_31521A8K3H34
Retinoic acid-induced protein 1RAI1 KIAA1820Q7Z5J44
Retinoic acid-induced protein 3 (G-protein coupled receptor family C group 5 member A) (Orphan G-protein-coupling receptor PEIG-1) (Retinoic acid-induced gene 1 protein) (RAIG-1)GPRC5A GPCR5A RAI3 RAIG1Q8NFJ54
Retinol dehydrogenase 13 (EC 1.1.1.-)RDH13 PSEC0082 UNQ736/PRO1430Q8NBN74
Retinol dehydrogenase 14 (EC 1.1.1.-) (Alcohol dehydrogenase PAN2)RDH14 PAN2 UNQ529/PRO1072Q9HBH54
Reversion-inducing cysteine-rich protein with Kazal motifs (hRECK) (Suppressor of tumorigenicity 15 protein)RECK ST15O959804
Rho GTPase-activating protein 11B (Rho-type GTPase-activating protein 11B)ARHGAP11BQ3KRB84
Rho GTPase-activating protein 12 (Rho-type GTPase-activating protein 12)ARHGAP12Q8IWW64
Rho GTPase-activating protein 24 (Filamin-A-associated RhoGAP) (FilGAP) (RAC1- and CDC42-specific GTPase-activating protein of 72 kDa) (RC-GAP72) (Rho-type GTPase-activating protein 24) (RhoGAP of 73 kDa) (Sarcoma antigen NY-SAR-88) (p73RhoGAP)ARHGAP24 FILGAPQ8N2644
Rho GTPase-activating protein 44 (NPC-A-10) (Rho-type GTPase-activating protein RICH2) (RhoGAP interacting with CIP4 homologs protein 2) (RICH-2)ARHGAP44 KIAA0672 RICH2Q17R894
Rho guanine nucleotide exchange factor 10-like protein (GrinchGEF)ARHGEF10L GRINCHGEF KIAA1626Q9HCE64
Rho guanine nucleotide exchange factor 19 (Ephexin-2)ARHGEF19Q8IW934
Rho guanine nucleotide exchange factor 35 (Rho guanine nucleotide exchange factor 5-like protein)ARHGEF35 ARHGEF5LA5YM694
Rho guanine nucleotide exchange factor 6 (Alpha-Pix) (COOL-2) (PAK-interacting exchange factor alpha) (Rac/Cdc42 guanine nucleotide exchange factor 6)ARHGEF6 COOL2 KIAA0006 PIXAQ150524
Rho-related BTB domain-containing protein 1RHOBTB1 KIAA0740O948444
Rho-related GTP-binding protein RhoB (Rho cDNA clone 6) (h6)RHOB ARH6 ARHBP627454
Rho-related GTP-binding protein RhoF (Rho family GTPase Rif) (Rho in filopodia)RHOF ARHF RIFQ9HBH04
Rho-related GTP-binding protein RhoN (Rho family GTPase 2) (Rho-related GTP-binding protein Rho7) (Rnd2)RND2 ARHN RHO7P521984
Rho-related GTP-binding protein RhoU (CDC42-like GTPase 1) (GTP-binding protein-like 1) (Rho GTPase-like protein ARHU) (Ryu GTPase) (Wnt-1 responsive Cdc42 homolog 1) (WRCH-1)RHOU ARHU CDC42L1 G28K WRCH1 SB128Q7L0Q84
Ribonuclease P protein subunit p29 (hPOP4) (EC 3.1.26.5)POP4 RPP29O957074
Ribonuclease P protein subunit p40 (RNaseP protein p40) (EC 3.1.26.5) (RNase P subunit 1)RPP40 RNASEP1O758184
Ribonuclease ZC3H12A (EC 3.1.-.-) (MCP-induced protein 1) (Zinc finger CCCH domain-containing protein 12A)ZC3H12A MCPIP MCPIP1Q5D1E84
Ribonucleoprotein PTB-binding 1RAVER1E9PAU24
Ribosomal biogenesis protein LAS1L (Protein LAS1 homolog)LAS1L MSTP060Q9Y4W24
Ribosomal protein L11, isoform CRA_b (cDNA, FLJ92077, Homo sapiens ribosomal protein L11 (RPL11), mRNA)RPL11 hCG_1739238Q5VVD04
Ribosomal protein S6 kinase alpha-3 (S6K-alpha-3) (EC 2.7.11.1) (90 kDa ribosomal protein S6 kinase 3) (p90-RSK 3) (p90RSK3) (Insulin-stimulated protein kinase 1) (ISPK-1) (MAP kinase-activated protein kinase 1b) (MAPK-activated protein kinase 1b) (MAPKAP kinase 1b) (MAPKAPK-1b) (Ribosomal S6 kinase 2) (RSK-2) (pp90RSK2)RPS6KA3 ISPK1 MAPKAPK1B RSK2P518124
Ribosomal protein S6 kinase beta-1 (S6K-beta-1) (S6K1) (EC 2.7.11.1) (70 kDa ribosomal protein S6 kinase 1) (P70S6K1) (p70-S6K 1) (Ribosomal protein S6 kinase I) (Serine/threonine-protein kinase 14A) (p70 ribosomal S6 kinase alpha) (p70 S6 kinase alpha) (p70 S6K-alpha) (p70 S6KA)RPS6KB1 STK14AP234434
Ribosomal RNA processing protein 36 homologRRP36 C6orf153 HSPC253Q96EU64
Ribosome biogenesis protein BOP1 (Block of proliferation 1 protein)BOP1 KIAA0124Q141374
Ribosome biogenesis protein TSR3 homologTSR3 C16orf42 UND313LQ9UJK04
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