EVpedia provide top 100+ EV markers, selected according to their identification number.
Based on EV proteomes, we defined the identification number of protein A as the number of datasets which contain protein A.
Therefore, proteins with higher identification numbers were more conserved.

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Protein name Gene symbol UniProt accession Identification number
Ribosome maturation protein SBDS (Shwachman-Bodian-Diamond syndrome protein)SBDS CGI-97Q9Y3A54
RILP-like protein 1 (Rab-interacting lysosomal-like protein 1)RILPL1 RLP1Q5EBL44
RING finger and SPRY domain-containing protein 1RSPRY1 KIAA1972 UNQ328/PRO444Q96DX44
RING finger protein 151RNF151Q2KHN14
RING finger protein 186RNF186Q9NXI64
RING finger protein 26RNF26Q9BY784
RING finger protein 38RNF38Q9H0F54
RING finger protein 44RNF44 KIAA1100Q7L0R74
RNA binding protein S1 (RNA binding protein S1, serine-rich domain, isoform CRA_a)RNPS1 rnps1 hCG_1989969D3DU924
RNA methyltransferase-like protein 1 (EC 2.1.1.-)RNMTL1 HC90Q9HC364
RNA polymerase-associated protein CTR9 homolog (SH2 domain-binding protein 1)CTR9 KIAA0155 SH2BP1Q6PD624
RNA polymerase-associated protein RTF1 homologRTF1 KIAA0252Q925414
RNA pseudouridylate synthase domain-containing protein 2RPUSD2 C15orf19Q8IZ734
RNA-binding E3 ubiquitin-protein ligase MEX3C (EC 6.3.2.-) (RING finger and KH domain-containing protein 2) (RING finger protein 194)MEX3C RKHD2 RNF194 BM-013Q5U5Q34
RNA-binding motif, single-stranded-interacting protein 2 (Suppressor of CDC2 with RNA-binding motif 3)RBMS2 SCR3Q154344
RNA-binding protein 12 (RNA-binding motif protein 12) (SH3/WW domain anchor protein in the nucleus) (SWAN)RBM12 KIAA0765 HRIHFB2091Q9NTZ64
RNA-binding protein Nova-1 (Neuro-oncological ventral antigen 1) (Onconeural ventral antigen 1) (Paraneoplastic Ri antigen) (Ventral neuron-specific protein 1)NOVA1P515134
RNP24 protein (Transmembrane emp24 domain trafficking protein 2, isoform CRA_a) (cDNA, FLJ93436, Homo sapiens coated vesicle membrane protein (RNP24), mRNA)RNP24 TMED2 hCG_1743563Q6FHT84
Rootletin (Ciliary rootlet coiled-coil protein)CROCC KIAA0445Q5TZA24
Roquin-2 (Membrane-associated nucleic acid-binding protein) (RING finger and CCCH-type zinc finger domain-containing protein 2) (RING finger protein 164)RC3H2 MNAB RNF164Q9HBD14
RRP12-like proteinRRP12 KIAA0690Q5JTH94
RWD domain-containing protein 2ARWDD2A RWDD2Q9UIY34
S1 RNA-binding domain-containing protein 1SRBD1Q8N5C64
SAM and SH3 domain-containing protein 1 (Proline-glutamate repeat-containing protein)SASH1 KIAA0790 PEPE1O948854
SCAN domain-containing protein 3 (Protein ZNF452) (Transposon-derived Buster4 transposase-like protein) (Zinc finger BED domain-containing protein 9)SCAND3 Buster4 KIAA1925 ZBED9 ZNF305P2 ZNF452Q6R2W34
Scavenger receptor class B member 1 (SRB1) (CD36 and LIMPII analogous 1) (CLA-1) (CD36 antigen-like 1) (Collagen type I receptor, thrombospondin receptor-like 1) (SR-BI) (CD antigen CD36)SCARB1 CD36L1 CLA1Q8WTV04
Schlafen family member 5SLFN5Q08AF34
SCL-interrupting locus protein (TAL-1-interrupting locus protein)STIL SILQ154684
SCY1-like protein 2 (Coated vesicle-associated kinase of 104 kDa)SCYL2 CVAK104 KIAA1360Q6P3W74
Sec1 family domain-containing protein 1 (SLY1 homolog) (Sly1p) (Syntaxin-binding protein 1-like 2)SCFD1 C14orf163 KIAA0917 STXBP1L2 FKSG23Q8WVM84
Secretory carrier-associated membrane protein 2 (Secretory carrier membrane protein 2)SCAMP2O151274
Segment polarity protein dishevelled homolog DVL-2 (Dishevelled-2) (DSH homolog 2)DVL2O146414
Selenoprotein M (SelM)SELM SEPMQ8WWX94
Selenoprotein S (SelS) (VCP-interacting membrane protein)VIMP SELS AD-015 SBBI8Q9BQE44
Sentrin-specific protease 6 (EC 3.4.22.68) (SUMO-1-specific protease 1) (Sentrin/SUMO-specific protease SENP6)SENP6 KIAA0797 SSP1 SUSP1 FKSG6Q9GZR14
Separin (EC 3.4.22.49) (Caspase-like protein ESPL1) (Extra spindle poles-like 1 protein) (Separase)ESPL1 ESP1 KIAA0165Q146744
Serine protease 57 (EC 3.4.21.-) (Serine protease 1-like protein 1)PRSS57 PRSSL1 UNQ782/PRO1599Q6UWY24
Serine/threonine-protein kinase 17B (EC 2.7.11.1) (DAP kinase-related apoptosis-inducing protein kinase 2)STK17B DRAK2O947684
Serine/threonine-protein kinase 38 (EC 2.7.11.1) (NDR1 protein kinase) (Nuclear Dbf2-related kinase 1)STK38 NDR1Q152084
Serine/threonine-protein kinase 38-like (EC 2.7.11.1) (NDR2 protein kinase) (Nuclear Dbf2-related kinase 2)STK38L KIAA0965 NDR2Q9Y2H14
Serine/threonine-protein kinase A-Raf (EC 2.7.11.1) (Proto-oncogene A-Raf) (Proto-oncogene A-Raf-1) (Proto-oncogene Pks)ARAF ARAF1 PKS PKS2P103984
Serine/threonine-protein kinase BRSK1 (EC 2.7.11.1) (Brain-selective kinase 1) (EC 2.7.11.26) (Brain-specific serine/threonine-protein kinase 1) (BR serine/threonine-protein kinase 1) (Serine/threonine-protein kinase SAD-B) (Synapses of Amphids Defective homolog 1) (SAD1 homolog) (hSAD1)BRSK1 KIAA1811 SAD1 SADBQ8TDC34
Serine/threonine-protein kinase BRSK2 (EC 2.7.11.1) (Brain-selective kinase 2) (EC 2.7.11.26) (Brain-specific serine/threonine-protein kinase 2) (BR serine/threonine-protein kinase 2) (Serine/threonine-protein kinase 29) (Serine/threonine-protein kinase SAD-A)BRSK2 C11orf7 PEN11B SADA STK29 HUSSY-12Q8IWQ34
Serine/threonine-protein kinase Chk1 (EC 2.7.11.1) (CHK1 checkpoint homolog) (Cell cycle checkpoint kinase) (Checkpoint kinase-1)CHEK1 CHK1O147574
Serine/threonine-protein kinase Nek3 (EC 2.7.11.1) (HSPK 36) (Never in mitosis A-related kinase 3) (NimA-related protein kinase 3)NEK3P519564
Serine/threonine-protein kinase NLK (EC 2.7.11.24) (Nemo-like kinase) (Protein LAK1)NLK LAK1Q9UBE84
Serine/threonine-protein kinase OSR1 (EC 2.7.11.1) (Oxidative stress-responsive 1 protein)OXSR1 KIAA1101 OSR1O957474
Serine/threonine-protein kinase pim-1 (EC 2.7.11.1)PIM1P113094
Serine/threonine-protein kinase receptor R3 (SKR3) (EC 2.7.11.30) (Activin receptor-like kinase 1) (ALK-1) (TGF-B superfamily receptor type I) (TSR-I)ACVRL1 ACVRLK1 ALK1P370234
Serine/threonine-protein kinase SBK1 (EC 2.7.11.1) (SH3-binding kinase 1)SBK1Q52WX24
Serine/threonine-protein kinase VRK1 (EC 2.7.11.1) (Vaccinia-related kinase 1)VRK1Q999864
Serine/threonine/tyrosine-interacting-like protein 1 (Dual specificity phosphatase inhibitor MK-STYX) (Dual specificity protein phosphatase 24) (Map kinase phosphatase-like protein MK-STYX)STYXL1 DUSP24 MKSTYXQ9Y6J84
Serpin B9 (Cytoplasmic antiproteinase 3) (CAP-3) (CAP3) (Peptidase inhibitor 9) (PI-9)SERPINB9 PI9P504534
Serpin H1 (47 kDa heat shock protein) (Arsenic-transactivated protein 3) (AsTP3) (Cell proliferation-inducing gene 14 protein) (Collagen-binding protein) (Colligin) (Rheumatoid arthritis-related antigen RA-A47)SERPINH1 CBP1 CBP2 HSP47 SERPINH2 PIG14P504544
Serum albuminALB GIG20 GIG42 PRO0903 PRO1708 PRO2044 PRO2619 PRO2675 UNQ696/PRO1341P027684
Serum amyloid A-4 protein (Constitutively expressed serum amyloid A protein) (C-SAA)SAA4 CSAAP355424
Serum paraoxonase/arylesterase 2 (PON 2) (EC 3.1.1.2) (EC 3.1.1.81) (Aromatic esterase 2) (A-esterase 2) (Serum aryldialkylphosphatase 2)PON2Q151654
SET domain-containing protein 5SETD5 KIAA1757Q9C0A64
Sex comb on midleg-like protein 2SCML2Q9UQR04
SF3A2 protein (Fragment)SF3A2Q05DF24
SH3 and multiple ankyrin repeat domains protein 2 (Shank2) (Cortactin-binding protein 1) (CortBP1) (Proline-rich synapse-associated protein 1)SHANK2 CORTBP1 KIAA1022 PROSAP1Q9UPX84
SH3 domain GRB2-like 1 (SH3-domain GRB2-like 1) (SH3-domain GRB2-like 1, isoform CRA_b) (SH3GL1 protein) (cDNA, FLJ96508, Homo sapiens SH3-domain GRB2-like 1 (SH3GL1), mRNA)SH3GL1 hCG_21932Q6FGM04
Short-chain dehydrogenase/reductase 3 (EC 1.1.1.300) (DD83.1) (Retinal short-chain dehydrogenase/reductase 1) (retSDR1)DHRS3 UNQ2424/PRO4983O759114
Sialate O-acetylesterase (EC 3.1.1.53) (H-Lse) (Sialic acid-specific 9-O-acetylesterase)SIAE YSG2Q9HAT24
Sialic acid-binding Ig-like lectin 12 (Siglec-12) (Sialic acid-binding Ig-like lectin-like 1) (Siglec-L1)SIGLEC12 SIGLECL1 SLG UNQ9215/PRO34042Q96PQ14
Sialic acid-binding Ig-like lectin 6 (Siglec-6) (CD33 antigen-like 1) (CDw327) (Obesity-binding protein 1) (OB-BP1) (CD antigen CD327)SIGLEC6 CD33L CD33L1 OBBP1O436994
Sideroflexin-4 (Breast cancer resistance marker 1)SFXN4 BCRM1Q6P4A74
Signal peptidase complex subunit 2 (EC 3.4.-.-) (Microsomal signal peptidase 25 kDa subunit) (SPase 25 kDa subunit)SPCS2 KIAA0102 SPC25Q150054
Signal transducing adapter molecule 2 (STAM-2) (Hrs-binding protein)STAM2 HBPO758864
Signal-induced proliferation-associated protein 1 (Sipa-1) (GTPase-activating protein Spa-1) (p130 SPA-1)SIPA1 SPA1Q96FS44
Similar to Kruppel-like factor 2 (Lung) (Fragment)0Q8IUN44
Sister chromatid cohesion protein DCC1 (Defective in sister chromatid cohesion protein 1 homolog)DSCC1 DCC1 UNQ9337/PRO34008Q9BVC34
Ski oncogene (Proto-oncogene c-Ski)SKIP127554
SLC29A2 protein0Q96FB24
SLC2A4 regulator (GLUT4 enhancer factor) (GEF) (Huntington disease gene regulatory region-binding protein 1) (HDBP-1)SLC2A4RG HDBP1Q9NR834
Small integral membrane protein 12SMIM12 C1orf212Q96EX14
Small integral membrane protein 3 (NGF-induced differentiation clone 67 protein) (Small membrane protein NID67)SMIM3 C5orf62 NID67Q9BZL34
Small integral membrane protein 4SMIM4 C3orf78Q8WVI04
Small nuclear protein PRAC1 (Prostate cancer susceptibility candidate protein 1) (Prostate, rectum and colon expressed gene protein)PRAC1 C17orf92 PRACQ96KF24
Small nuclear ribonucleoprotein Sm D3 (Sm-D3) (snRNP core protein D3)SNRPD3P623184
Smith-Magenis syndrome chromosomal region candidate gene 8 proteinSMCR8Q8TEV94
SNF-related serine/threonine-protein kinase (EC 2.7.11.1) (SNF1-related kinase)SNRK KIAA0096 SNFRKQ9NRH24
SOCS3 protein (Suppressor of cytokine signaling 3, isoform CRA_a) (cDNA, FLJ94944, highly similar to Homo sapiens suppressor of cytokine signaling 3 (SOCS3), mRNA)SOCS3 hCG_1776363Q6FI394
Sodium-coupled neutral amino acid transporter 1 (Amino acid transporter A1) (N-system amino acid transporter 2) (Solute carrier family 38 member 1) (System A amino acid transporter 1) (System N amino acid transporter 1)SLC38A1 ATA1 NAT2 SAT1 SNAT1Q9H2H94
Sodium-coupled neutral amino acid transporter 2 (Amino acid transporter A2) (Protein 40-9-1) (Solute carrier family 38 member 2) (System A amino acid transporter 2) (System A transporter 1) (System N amino acid transporter 2)SLC38A2 ATA2 KIAA1382 SAT2 SNAT2Q96QD84
Sodium-dependent phosphate transporter 2 (Gibbon ape leukemia virus receptor 2) (GLVR-2) (Phosphate transporter 2) (PiT-2) (Pit2) (hPit2) (Solute carrier family 20 member 2)SLC20A2 GLVR2 PIT2Q083574
Solute carrier family 13 member 3 (Na(+)/dicarboxylate cotransporter 3) (NaDC-3) (hNaDC3) (Sodium-dependent high-affinity dicarboxylate transporter 2)SLC13A3 NADC3 SDCT2Q8WWT94
Solute carrier family 15 member 4 (Peptide transporter 4) (Peptide/histidine transporter 1) (hPHT1)SLC15A4 PHT1 PTR4 FP12591Q8N6974
Solute carrier family 2, (Facilitated glucose transporter) member 8, isoform CRA_dSLC2A8 hCG_28276Q8WZ054
Solute carrier family 22 member 3 (Extraneuronal monoamine transporter) (EMT) (Organic cation transporter 3)SLC22A3 EMTH OCT3O757514
Solute carrier family 25 member 38SLC25A38Q96DW64
Solute carrier family 25 member 47 (Hepatocellular carcinoma down-regulated mitochondrial carrier protein)SLC25A47 C14orf68 HDMCP HMFN1655Q6Q0C14
Solute carrier family 35 member E3 (Bladder cancer-overexpressed gene 1 protein)SLC35E3 BLOV1 UNQ3043/PRO9859Q7Z7694
Solute carrier family 41 member 3SLC41A3Q96GZ64
Son of sevenless homolog 2 (SOS-2)SOS2Q078904
Sorting nexin-1SNX1Q135964
Sorting nexin-15SNX15Q9NRS64
Sorting nexin-4SNX4O952194
Speedy protein C (Rapid inducer of G2/M progression in oocytes C) (RINGO C) (hSpy/Ringo C)SPDYCQ5MJ684
Sperm flagellar protein 1SPEF1 C20orf28Q9Y4P94
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