EVpedia provide top 100+ EV markers, selected according to their identification number.
Based on EV proteomes, we defined the identification number of protein A as the number of datasets which contain protein A.
Therefore, proteins with higher identification numbers were more conserved.

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Protein name Gene symbol UniProt accession Identification number
Transmembrane protein 61TMEM61Q8N0U24
Transmembrane protein 69TMEM69 C1orf154 HSPC229Q5SWH94
Transmembrane protein 72 (Kidney-specific secretory protein of 37 kDa)TMEM72 C10orf127 KSP37A0PK054
Transmembrane protein 82TMEM82A0PJX84
Transmembrane protein 87ATMEM87A PSEC0094Q8NBN34
Transmembrane protein 8A (Protein M83) (Transmembrane protein 6) (Transmembrane protein 8)TMEM8A TMEM6 TMEM8Q9HCN34
Transport and Golgi organization protein 2 homologTANGO2 C22orf25Q6ICL34
Transporter0B2R7Y74
Trefoil factor 1 (Breast cancer estrogen-inducible protein) (PNR-2) (Polypeptide P1.A) (hP1.A) (Protein pS2)TFF1 BCEI PS2P041554
Tripartite motif-containing protein 47 (Gene overexpressed in astrocytoma protein) (RING finger protein 100)TRIM47 GOA RNF100Q96LD44
Tripartite motif-containing protein 49 (RING finger protein 18) (Testis-specific RING-finger protein)TRIM49 RNF18P0CI254
Tripeptidyl-peptidase 1 (TPP-1) (EC 3.4.14.9) (Cell growth-inhibiting gene 1 protein) (Lysosomal pepstatin-insensitive protease) (LPIC) (Tripeptidyl aminopeptidase) (Tripeptidyl-peptidase I) (TPP-I)TPP1 CLN2 GIG1 UNQ267/PRO304O147734
Triple QxxK/R motif-containing protein (Triple repetitive-sequence of QXXK/R protein homolog)TRIQK C8orf83Q629K14
tRNA (adenine(58)-N(1))-methyltransferase, mitochondrial (EC 2.1.1.220)TRMT61BQ9BVS54
tRNA (cytosine(34)-C(5))-methyltransferase (EC 2.1.1.203) (Myc-induced SUN domain-containing protein) (Misu) (NOL1/NOP2/Sun domain family member 2) (Substrate of AIM1/Aurora kinase B) (tRNA (cytosine-5-)-methyltransferase) (tRNA methyltransferase 4 homolog) (hTrm4)NSUN2 SAKI TRM4Q08J234
tRNA pseudouridine synthase (EC 5.4.99.-)0E5KMT54
tRNA pseudouridine synthase A, mitochondrial (EC 5.4.99.12) (tRNA pseudouridine(38-40) synthase) (tRNA pseudouridylate synthase I) (tRNA-uridine isomerase I)PUS1 PP8985Q9Y6064
Tuberin (Tuberous sclerosis 2 protein)TSC2 TSC4P498154
Tubulin beta-4A chain (Tubulin 5 beta) (Tubulin beta-4 chain)TUBB4A TUBB4 TUBB5P043504
Tubulin beta-8 chainTUBB8Q3ZCM74
Tubulin polyglutamylase complex subunit 1 (PGs1)TPGS1 C19orf20Q6ZTW04
Tubulin, beta, 4 variant (Fragment)0Q53G924
Tumor necrosis factor receptor superfamily member 11B (Osteoclastogenesis inhibitory factor) (Osteoprotegerin)TNFRSF11B OCIF OPGO003004
Tumor necrosis factor receptor superfamily member 25 (Apo-3) (Apoptosis-inducing receptor AIR) (Apoptosis-mediating receptor DR3) (Apoptosis-mediating receptor TRAMP) (Death receptor 3) (Lymphocyte-associated receptor of death) (LARD) (Protein WSL) (Protein WSL-1)TNFRSF25 APO3 DDR3 DR3 TNFRSF12 WSL WSL1 UNQ455/PRO779Q930384
Tumor necrosis factor receptor superfamily member 5 (B-cell surface antigen CD40) (Bp50) (CD40L receptor) (CDw40) (CD antigen CD40)CD40 TNFRSF5P259424
Tumor protein p53-inducible nuclear protein 1 (Stress-induced protein) (p53-dependent damage-inducible nuclear protein 1) (p53DINP1)TP53INP1 P53DINP1 SIPQ96A564
Tumor protein p53-inducible protein 13 (Damage-stimulated cytoplasmic protein 1)TP53I13 DSCP1Q8NBR04
Tumor suppressor candidate 2 (Fusion 1 protein) (Fus-1 protein) (PDGFA-associated protein 2)TUSC2 C3orf11 FUS1 LGCC PDAP2O758964
Tumor susceptibility gene 101 protein (ESCRT-I complex subunit TSG101)TSG101Q998164
Tyrosine-protein kinase ABL1 (EC 2.7.10.2) (Abelson murine leukemia viral oncogene homolog 1) (Abelson tyrosine-protein kinase 1) (Proto-oncogene c-Abl) (p150)ABL1 ABL JTK7P005194
Tyrosine-protein kinase Fgr (EC 2.7.10.2) (Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog) (Proto-oncogene c-Fgr) (p55-Fgr) (p58-Fgr) (p58c-Fgr)FGR SRC2P097694
Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Fas-associated protein-tyrosine phosphatase 1) (FAP-1) (PTP-BAS) (Protein-tyrosine phosphatase 1E) (PTP-E1) (hPTPE1) (Protein-tyrosine phosphatase PTPL1)PTPN13 PNP1 PTP1E PTPL1Q129234
U11/U12 small nuclear ribonucleoprotein 35 kDa protein (U11/U12 snRNP 35 kDa protein) (U11/U12-35K) (Protein HM-1) (U1 snRNP-binding protein homolog)SNRNP35 HM1 U1SNRNPBPQ165604
U11/U12 small nuclear ribonucleoprotein 48 kDa protein (U11/U12 snRNP 48 kDa protein) (U11/U12-48K)SNRNP48 C6orf151Q6IEG04
U2 snRNP-associated SURP motif-containing protein (140 kDa Ser/Arg-rich domain protein) (U2-associated protein SR140)U2SURP KIAA0332 SR140O150424
UBA-like domain-containing protein 1UBALD1 FAM100A PP11303Q8TB054
UbiA prenyltransferase domain-containing protein 1 (EC 2.5.1.-) (Transitional epithelial response protein 1)UBIAD1 TERE1Q9Y5Z94
Ubinuclein-1 (HIRA-binding protein) (Protein VT4) (Ubiquitously expressed nuclear protein)UBN1Q9NPG34
Ubiquitin carboxyl-terminal hydrolase 24 (EC 3.4.19.12) (Deubiquitinating enzyme 24) (Ubiquitin thioesterase 24) (Ubiquitin-specific-processing protease 24)USP24 KIAA1057Q9UPU54
Ubiquitin carboxyl-terminal hydrolase 49 (EC 3.4.19.12) (Deubiquitinating enzyme 49) (Ubiquitin thioesterase 49) (Ubiquitin-specific-processing protease 49)USP49Q70CQ14
Ubiquitin domain-containing protein 1UBTD1Q9HAC84
Ubiquitin fusion degradation protein 1 homolog (UB fusion protein 1)UFD1LQ928904
Ubiquitin-conjugating enzyme E2 E2 (EC 6.3.2.19) (UbcH8) (Ubiquitin carrier protein E2) (Ubiquitin-protein ligase E2)UBE2E2 UBCH8Q96LR54
Ubiquitin-conjugating enzyme E2 O (EC 6.3.2.19) (Ubiquitin carrier protein O) (Ubiquitin-conjugating enzyme E2 of 230 kDa) (Ubiquitin-conjugating enzyme E2-230K) (Ubiquitin-protein ligase O)UBE2O KIAA1734Q9C0C94
Ubiquitin-conjugating enzyme E2 variant 2 (DDVit 1) (Enterocyte differentiation-associated factor 1) (EDAF-1) (Enterocyte differentiation-promoting factor 1) (EDPF-1) (MMS2 homolog) (Vitamin D3-inducible protein)UBE2V2 MMS2 UEV2Q158194
Ubiquitin-like-conjugating enzyme ATG3 (EC 6.3.2.-) (Autophagy-related protein 3) (APG3-like) (hApg3) (Protein PC3-96)ATG3 APG3 APG3LQ9NT624
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 7 (BGnT-7) (Beta-1,3-Gn-T7) (Beta-1,3-N-acetylglucosaminyltransferase 7) (Beta3Gn-T7) (EC 2.4.1.-)B3GNT7Q8NFL04
UDP-glucose:glycoprotein glucosyltransferase 2 (UGT2) (hUGT2) (EC 2.4.1.-) (UDP--Glc:glycoprotein glucosyltransferase 2) (UDP-glucose ceramide glucosyltransferase-like 1)UGGT2 UGCGL2 UGT2Q9NYU14
UNC119-binding protein C5orf30C5orf30Q96GV94
Uncharacterized coiled-coil domain-containing protein KIAA1984KIAA1984Q5T5S14
Uncharacterized protein C11orf95C11orf95C9JLR94
Uncharacterized protein C14orf80C14orf80Q86SX34
Uncharacterized protein C15orf41 (Protein HH114)C15orf41Q9Y2V04
Uncharacterized protein C16orf86C16orf86Q6ZW134
Uncharacterized protein C1orf131C1orf131Q8NDD14
Uncharacterized protein C1orf159C1orf159 UNQ2998/PRO9739Q96HA44
Uncharacterized protein C1orf54C1orf54Q8WWF14
Uncharacterized protein C22orf15 (Protein N27C7-3)C22orf15Q8WYQ44
Uncharacterized protein C22orf46C22orf46C9J4424
Uncharacterized protein C4orf3 (Hepatitis C virus F protein-transactivated protein 1) (HCV F-transactivated protein 1)C4orf3Q8WVX34
Uncharacterized protein C4orf46C4orf46Q504U04
Uncharacterized protein C6orf136C6orf136Q5SQH84
Uncharacterized protein C6orf226C6orf226Q5I0X44
Uncharacterized protein C9orf78 (Hepatocellular carcinoma-associated antigen 59)C9orf78 HCA59Q9NZ634
Uncharacterized protein CXorf38CXorf38Q8TB034
Uncharacterized protein CXorf48 (Cancer/testis antigen 55) (CT55) (Tumor antigen BJ-HCC-20)CXorf48Q8WUE54
Uncharacterized protein KIAA1143KIAA1143Q96AT14
Unconventional myosin-Ib (MYH-1c) (Myosin I alpha) (MMI-alpha) (MMIa)MYO1BO437954
Unconventional myosin-VI (Unconventional myosin-6)MYO6 KIAA0389Q9UM544
UPF0235 protein C15orf40C15orf40Q8WUR74
UPF0378 protein KIAA0100 (Antigen MLAA-22) (Breast cancer-overexpressed gene 1 protein)KIAA0100 BCOX1Q146674
UPF0471 protein C1orf63C1orf63 HT033 NPD014Q9BUV04
UPF0501 protein KIAA1430KIAA1430Q9P2B74
UPF0515 protein C19orf66C19orf66Q9NUL54
UPF0538 protein C2orf76C2orf76Q3KRA64
UPF0556 protein C19orf10 (Interleukin-25) (IL-25) (Stromal cell-derived growth factor SF20)C19orf10 IL25Q969H84
UPF0574 protein C9orf169C9orf169A8MQ034
UPF0598 protein C8orf82C8orf82Q6P1X64
UPF0668 protein C10orf76C10orf76Q5T2E64
UPF0687 protein C20orf27C20orf27Q9GZN84
UPF0688 protein C1orf174C1orf174Q8IYL34
UPF0692 protein C19orf54C19orf54Q5BKX54
Upstream stimulatory factor 1 (Class B basic helix-loop-helix protein 11) (bHLHb11) (Major late transcription factor 1)USF1 BHLHB11 USFP224154
USP6 N-terminal-like protein (Related to the N-terminus of tre) (RN-tre)USP6NL KIAA0019Q927384
V-type proton ATPase 116 kDa subunit a isoform 1 (V-ATPase 116 kDa isoform a1) (Clathrin-coated vesicle/synaptic vesicle proton pump 116 kDa subunit) (Vacuolar adenosine triphosphatase subunit Ac116) (Vacuolar proton pump subunit 1) (Vacuolar proton translocating ATPase 116 kDa subunit a isoform 1)ATP6V0A1 ATP6N1 ATP6N1A VPP1Q930504
V-type proton ATPase subunit B, kidney isoform (V-ATPase subunit B 1) (Endomembrane proton pump 58 kDa subunit) (Vacuolar proton pump subunit B 1)ATP6V1B1 ATP6B1 VATB VPP3P153134
Vacuolar fusion protein CCZ1 homologCCZ1 C7orf28A CGI-43P867914
Vacuolar protein sorting-associated protein 13B (Cohen syndrome protein 1)VPS13B CHS1 COH1 KIAA0532Q7Z7G84
Vacuolar protein sorting-associated protein 16 homolog (hVPS16)VPS16Q9H2694
Vacuolar protein sorting-associated protein 28 homolog (H-Vps28) (ESCRT-I complex subunit VPS28)VPS28Q9UK414
Vacuolar protein sorting-associated protein 37D (ESCRT-I complex subunit VPS37D) (Williams-Beuren syndrome chromosomal region 24 protein)VPS37D WBSCR24Q86XT24
Vacuolar protein sorting-associated protein 4B (EC 3.6.4.6) (Cell migration-inducing gene 1 protein) (Suppressor of K(+) transport growth defect 1) (Protein SKD1)VPS4B SKD1 VPS42 MIG1O753514
Vacuolar protein sorting-associated protein 72 homolog (Protein YL-1) (Transcription factor-like 1)VPS72 TCFL1 YL1Q159064
Vacuole membrane protein 1 (Transmembrane protein 49)VMP1 TDC1 TMEM49 HSPC292Q96GC94
Vascular endothelial growth factor receptor 3 (VEGFR-3) (EC 2.7.10.1) (Fms-like tyrosine kinase 4) (FLT-4) (Tyrosine-protein kinase receptor FLT4)FLT4 VEGFR3P359164
VCP protein (Fragment)VCPQ96IF94
Vesicle transport protein GOT1A (Golgi transport 1 homolog A) (hGOT1b)GOLT1A GOT1BQ6ZVE74
Vesicle transport through interaction with t-SNAREs homolog 1B (Vesicle transport v-SNARE protein Vti1-like 1) (Vti1-rp1)VTI1B VTI1 VTI1L VTI1L1 VTI2Q9UEU04
Vesicle-associated membrane protein 2 (VAMP-2) (Synaptobrevin-2)VAMP2 SYB2P630274
Vesicle-trafficking protein SEC22a (SEC22 vesicle-trafficking protein homolog A) (SEC22 vesicle-trafficking protein-like 2)SEC22A SEC22L2Q96IW74
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