EVpedia provide top 100+ EV markers, selected according to their identification number.
Based on EV proteomes, we defined the identification number of protein A as the number of datasets which contain protein A.
Therefore, proteins with higher identification numbers were more conserved.

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Protein name Gene symbol UniProt accession Identification number
60 kDa lysophospholipase (EC 3.1.1.5) [Includes: L-asparaginase (EC 3.5.1.1) (L-asparagine amidohydrolase); Platelet-activating factor acetylhydrolase (PAF acetylhydrolase) (EC 3.1.1.47)]ASPG C14orf76Q86U103
60S ribosomal protein L3-likeRPL3LQ929013
7-dehydrocholesterol reductase (7-DHC reductase) (EC 1.3.1.21) (Putative sterol reductase SR-2) (Sterol Delta(7)-reductase)DHCR7 D7SRQ9UBM73
72 kDa type IV collagenase (EC 3.4.24.24) (72 kDa gelatinase) (Gelatinase A) (Matrix metalloproteinase-2) (MMP-2) (TBE-1) [Cleaved into: PEX]MMP2 CLG4AP082533
78 kDa glucose-regulated protein (GRP-78) (Endoplasmic reticulum lumenal Ca(2+)-binding protein grp78) (Heat shock 70 kDa protein 5) (Immunoglobulin heavy chain-binding protein) (BiP)HSPA5 GRP78P110213
A-kinase anchor protein 10, mitochondrial (AKAP-10) (Dual specificity A kinase-anchoring protein 2) (D-AKAP-2) (Protein kinase A-anchoring protein 10) (PRKA10)AKAP10O435723
Abhydrolase domain-containing protein 16A (EC 3.-.-.-) (HLA-B-associated transcript 5) (Protein G5)ABHD16A BAT5 G5 NG26 PP199O958703
Abhydrolase domain-containing protein 8 (EC 3.-.-.-)ABHD8Q96I133
Acetylcholine receptor subunit gammaCHRNG ACHRGP075103
Acid sphingomyelinase-like phosphodiesterase 3b (ASM-like phosphodiesterase 3b) (EC 3.1.4.-)SMPDL3B ASML3BQ924853
Acrosin (EC 3.4.21.10) [Cleaved into: Acrosin light chain; Acrosin heavy chain]ACR ACRSP103233
Actin, aortic smooth muscle (Alpha-actin-2) (Cell growth-inhibiting gene 46 protein)ACTA2 ACTSA ACTVS GIG46P627363
Activated RNA polymerase II transcriptional coactivator p15 (Positive cofactor 4) (PC4) (SUB1 homolog) (p14)SUB1 PC4 RPO2TC1P539993
Activating signal cointegrator 1 complex subunit 3 (EC 3.6.4.12) (ASC-1 complex subunit p200) (ASC1p200) (Helicase, ATP binding 1) (Trip4 complex subunit p200)ASCC3 HELIC1Q8N3C03
Acyl-CoA dehydrogenase family member 10 (ACAD-10) (EC 1.3.99.-)ACAD10Q6JQN13
Acyl-CoA dehydrogenase family member 11 (ACAD-11) (EC 1.3.99.-)ACAD11Q709F03
Acyl-CoA-binding domain-containing protein 5ACBD5 KIAA1996Q5T8D33
Acyl-CoA-binding domain-containing protein 6ACBD6Q9BR613
Acyl-CoA:lysophosphatidylglycerol acyltransferase 1 (EC 2.3.1.-)LPGAT1 FAM34A KIAA0205Q926043
Acyl-coenzyme A synthetase ACSM5, mitochondrial (EC 6.2.1.2) (Acyl-CoA synthetase medium-chain family member 5)ACSM5 MACS3Q6NUN03
Acyl-coenzyme A thioesterase 4 (Acyl-CoA thioesterase 4) (EC 3.1.2.2) (PTE-2b) (Peroxisomal acyl coenzyme A thioester hydrolase Ib) (Peroxisomal long-chain acyl-CoA thioesterase Ib) (PTE-Ib)ACOT4 PTE2B PTEIBQ8N9L93
ADAMTS-like protein 4 (ADAMTSL-4) (Thrombospondin repeat-containing protein 1)ADAMTSL4 TSRC1 PP1396 UNQ2803/PRO34012Q6UY143
Adaptin ear-binding coat-associated protein 2 (NECAP endocytosis-associated protein 2) (NECAP-2)NECAP2Q9NVZ33
Adenosine receptor A2aADORA2A ADORA2P292743
Adipocyte plasma membrane-associated protein (Protein BSCv)APMAP C20orf3 UNQ1869/PRO4305Q9HDC93
ADM2 (Intermedin) [Cleaved into: Adrenomedullin-2 (AM2) (Intermedin-long) (IMDL); Intermedin-short (IMDS)]ADM2 AM2Q7Z4H43
ADP-ribose pyrophosphatase, mitochondrial (EC 3.6.1.13) (ADP-ribose diphosphatase) (ADP-ribose phosphohydrolase) (Adenosine diphosphoribose pyrophosphatase) (ADPR-PPase) (Nucleoside diphosphate-linked moiety X motif 9) (Nudix motif 9)NUDT9 NUDT10 PSEC0099 UNQ3012/PRO9771Q9BW913
ADP-ribosylation factor 5 (ADP-ribosylation factor 5, isoform CRA_a) (cDNA, FLJ92389, Homo sapiens ADP-ribosylation factor 5 (ARF5), mRNA)ARF5 hCG_32325 tcag7.6A4D0Z33
ADP-ribosylation factor-binding protein GGA3 (Golgi-localized, gamma ear-containing, ARF-binding protein 3)GGA3 KIAA0154Q9NZ523
ADP-ribosylation factor-like 2 (ADP-ribosylation factor-like 2 variant) (HCG23373, isoform CRA_a)hCG_23373Q53YD83
ADP-ribosylation factor-like protein 14 (ADP-ribosylation factor 7)ARL14 ARF7Q8N4G23
Adropin (Energy homeostasis-associated protein)ENHO C9orf165 UNQ470/PRO830Q6UWT23
Adseverin (Scinderin)SCIN KIAA1905Q9Y6U33
AF1Q protein (Myeloid/lymphoid or mixed-lineage leukemia (Trithorax homolog, Drosophila) translocated to, 11) (Myeloid/lymphoid or mixed-lineage leukemia (Trithorax homolog, Drosophila); translocated to, 11) (cDNA FLJ31527 fis, clone NT2RI2000344, highly similar to Protein AF1q) (Fragment)AF1Q MLLT11 hCG_1778767Q6FGF73
AF4/FMR2 family member 3 (Lymphoid nuclear protein related to AF4) (Protein LAF-4)AFF3 LAF4P518263
Afadin- and alpha-actinin-binding protein (ADIP) (Afadin DIL domain-interacting protein) (SSX2-interacting protein)SSX2IP KIAA0923Q9Y2D83
Aflatoxin B1 aldehyde reductase member 3 (EC 1.-.-.-) (AFB1 aldehyde reductase 2) (AFB1-AR 2)AKR7A3 AFAR2O951543
AftiphilinAFTPH AFTHQ6ULP23
AGAP3 protein (Fragment)AGAP3Q86XV53
Agouti-signaling protein (ASP) (Agouti switch protein)ASIP AGTI AGTIL ASPP421273
Alanine--tRNA ligase, mitochondrial (EC 6.1.1.7) (Alanyl-tRNA synthetase) (AlaRS)AARS2 AARSL KIAA1270Q5JTZ93
Aldehyde dehydrogenase 9 family, member A1ALDH9A1 hCG_21745B9EKV43
Aldehyde dehydrogenase family 3 member B1 (EC 1.2.1.5) (Aldehyde dehydrogenase 7)ALDH3B1 ALDH7P433533
Aldehyde dehydrogenase family 8 member A1 (EC 1.2.1.-) (Aldehyde dehydrogenase 12)ALDH8A1 ALDH12Q9H2A23
Aldo-keto reductase family 1 member B10 (EC 1.1.1.-) (ARL-1) (Aldose reductase-like) (Aldose reductase-related protein) (ARP) (hARP) (Small intestine reductase) (SI reductase)AKR1B10 AKR1B11O602183
Aldo-keto reductase family 1 member C3 (EC 1.-.-.-) (17-beta-hydroxysteroid dehydrogenase type 5) (17-beta-HSD 5) (3-alpha-HSD type II, brain) (3-alpha-hydroxysteroid dehydrogenase type 2) (3-alpha-HSD type 2) (EC 1.1.1.357) (Chlordecone reductase homolog HAKRb) (Dihydrodiol dehydrogenase 3) (DD-3) (DD3) (Dihydrodiol dehydrogenase type I) (HA1753) (Indanol dehydrogenase) (EC 1.1.1.112) (Prostaglandin F synthase) (PGFS) (EC 1.1.1.188) (Testosterone 17-beta-dehydrogenase 5) (EC 1.1.1.239) (EC 1.1.1.64) (Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase) (EC 1.3.1.20)AKR1C3 DDH1 HSD17B5 KIAA0119 PGFSP423303
Alpha-1,2-mannosyltransferase ALG9 (EC 2.4.1.259) (EC 2.4.1.261) (Asparagine-linked glycosylation protein 9 homolog) (Disrupted in bipolar disorder protein 1) (Dol-P-Man:Man(6)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase) (Dol-P-Man:Man(8)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase)ALG9 DIBD1Q9H6U83
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase (EC 2.4.1.143) (Beta-1,2-N-acetylglucosaminyltransferase II) (GlcNAc-T II) (GNT-II) (Mannoside acetylglucosaminyltransferase 2) (N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase II)MGAT2Q104693
Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A (EC 2.4.1.155) (Alpha-mannoside beta-1,6-N-acetylglucosaminyltransferase) (GlcNAc-T V) (GNT-V) (Mannoside acetylglucosaminyltransferase 5) (N-acetylglucosaminyl-transferase V)MGAT5 GGNT5Q093283
Alpha-1-acid glycoprotein 2 (AGP 2) (Orosomucoid-2) (OMD 2)ORM2 AGP2P196523
Alpha-2C adrenergic receptor (Alpha-2 adrenergic receptor subtype C4) (Alpha-2C adrenoreceptor) (Alpha-2C adrenoceptor) (Alpha-2CAR)ADRA2C ADRA2L2 ADRA2RL2P188253
Alpha-crystallin A chain (Heat shock protein beta-4) (HspB4) [Cleaved into: Alpha-crystallin A(1-172); Alpha-crystallin A(1-168); Alpha-crystallin A(1-162)]CRYAA CRYA1 HSPB4P024893
Alpha-crystallin B chain (Alpha(B)-crystallin) (Heat shock protein beta-5) (HspB5) (Renal carcinoma antigen NY-REN-27) (Rosenthal fiber component)CRYAB CRYA2P025113
Alpha-fetoprotein (Alpha-1-fetoprotein) (Alpha-fetoglobulin)AFP HPAFPP027713
Alpha-globin transcription factor CP2 (SAA3 enhancer factor) (Transcription factor LSF)TFCP2 LSF SEFQ128003
Alpha-ketoglutarate-dependent dioxygenase FTO (EC 1.14.11.-) (Fat mass and obesity-associated protein)FTO KIAA1752Q9C0B13
Alpha-methylacyl-CoA racemase (EC 5.1.99.4) (2-methylacyl-CoA racemase)AMACRQ9UHK63
Alpha/beta hydrolase domain-containing protein 13 (Abhydrolase domain-containing protein 13) (EC 3.-.-.-)ABHD13 C13orf6Q7L2113
Alpha/beta hydrolase domain-containing protein 14A (Abhydrolase domain-containing protein 14A) (EC 3.-.-.-)ABHD14A UNQ1913/PRO4373Q9BUJ03
Alsin (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 6 protein) (Amyotrophic lateral sclerosis 2 protein)ALS2 ALS2CR6 KIAA1563Q96Q423
Alternative prion protein (AltPrP)0F7VJQ13
Aminomethyltransferase, mitochondrial (EC 2.1.2.10) (Glycine cleavage system T protein) (GCVT)AMT GCSTP487283
AMY1A protein (Fragment)AMY1AQ6NSB33
Androgen-dependent TFPI-regulating proteinADTRP C6orf105Q96IZ23
Androgen-induced gene 1 protein (AIG-1)AIG1 CGI-103Q9NVV53
Angiopoietin-4 (ANG-4) (Angiopoietin-3) (ANG-3)ANGPT4 ANG3 ANG4Q9Y2643
Ankyrin repeat and SAM domain-containing protein 3ANKS3 KIAA1977Q6ZW763
Ankyrin repeat and SOCS box protein 1 (ASB-1)ASB1 KIAA1146Q9Y5763
Ankyrin repeat and SOCS box protein 13 (ASB-13)ASB13Q8WXK33
Ankyrin repeat and SOCS box protein 3 (ASB-3)ASB3Q9Y5753
Ankyrin repeat and SOCS box protein 6 (ASB-6)ASB6Q9NWX53
Ankyrin repeat and SOCS box protein 9 (ASB-9)ASB9Q96DX53
Ankyrin repeat and zinc finger domain-containing protein 1 (Zinc finger protein 744)ANKZF1 ZNF744Q9H8Y53
Ankyrin repeat domain-containing protein 30B (Serologically defined breast cancer antigen NY-BR-1.1)ANKRD30BQ9BXX23
Ankyrin repeat domain-containing protein 35ANKRD35Q8N2833
Ankyrin repeat domain-containing protein 39ANKRD39 HSPC200Q53RE83
Ankyrin repeat domain-containing protein 46 (Ankyrin repeat small protein) (ANK-S)ANKRD46Q86W743
Ankyrin repeat domain-containing protein 53ANKRD53Q8N9V63
Ankyrin repeat family A protein 2 (RFXANK-like protein 2)ANKRA2 ANKRAQ9H9E13
Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin)ANK1 ANKP161573
Ankyrin-2 (ANK-2) (Ankyrin-B) (Brain ankyrin) (Non-erythroid ankyrin)ANK2Q014843
AnnexinANXA11 hCG_22492Q5T0G83
Annexin A9 (Annexin XXXI) (Annexin-31) (Annexin-9) (Pemphaxin)ANXA9 ANX31O760273
Anoctamin-10 (Transmembrane protein 16K)ANO10 TMEM16KQ9NW153
Anoctamin-9 (Transmembrane protein 16J) (Tumor protein p53-inducible protein 5) (p53-induced gene 5 protein)ANO9 PIG5 TMEM16J TP53I5A1A5B43
AP-1 complex subunit gamma-1 (Adapter-related protein complex 1 subunit gamma-1) (Adaptor protein complex AP-1 subunit gamma-1) (Clathrin assembly protein complex 1 gamma-1 large chain) (Gamma1-adaptin) (Golgi adaptor HA1/AP1 adaptin subunit gamma-1)AP1G1 ADTG CLAPG1O437473
AP-1 complex subunit mu-1 (AP-mu chain family member mu1A) (Adapter-related protein complex 1 subunit mu-1) (Adaptor protein complex AP-1 subunit mu-1) (Clathrin assembly protein complex 1 mu-1 medium chain 1) (Clathrin coat assembly protein AP47) (Clathrin coat-associated protein AP47) (Golgi adaptor HA1/AP1 adaptin mu-1 subunit) (Mu-adaptin 1) (Mu1A-adaptin)AP1M1 CLTNMQ9BXS53
AP2-associated protein kinase 1 (EC 2.7.11.1) (Adaptor-associated kinase 1)AAK1 KIAA1048Q2M2I83
APC variant protein (Fragment)APC variant proteinQ4LE703
Apical endosomal glycoprotein (MAM domain-containing protein 4)MAMDC4 AEGP UNQ3001/PRO9742Q6UXC13
Apolipoprotein B mRNA editing enzyme catalytic polypeptide-like 3DE (HCG41704, isoform CRA_a)APOBEC3DE hCG_41704B2CML43
Apolipoprotein L1 (cDNA FLJ59906, moderately similar to Apolipoprotein-L1)APOL1B1AH953
Apolipoprotein L3 (Apolipoprotein L-III) (ApoL-III) (TNF-inducible protein CG12-1) (CG12_1)APOL3O952363
Apoptosis facilitator Bcl-2-like protein 14 (Bcl2-L-14) (Apoptosis regulator Bcl-G)BCL2L14 BCLGQ9BZR83
Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B)PPP1R13B ASPP1 KIAA0771Q96KQ43
Aquaporin-5 (AQP-5)AQP5P550643
Arachidonate 12-lipoxygenase, 12R-type (12R-LOX) (12R-lipoxygenase) (EC 1.13.11.-) (Epidermis-type lipoxygenase 12)ALOX12BO753423
ARF GTPase-activating protein GIT2 (ARF GAP GIT2) (Cool-interacting tyrosine-phosphorylated protein 2) (CAT-2) (CAT2) (G protein-coupled receptor kinase-interactor 2) (GRK-interacting protein 2)GIT2 KIAA0148Q141613
Arf-GAP domain and FG repeat-containing protein 1 (HIV-1 Rev-binding protein) (Nucleoporin-like protein RIP) (Rev-interacting protein) (Rev/Rex activation domain-binding protein)AGFG1 HRB RAB RIPP525943
Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 2 (Centaurin-beta-2) (Cnt-b2)ACAP2 CENTB2 KIAA0041Q150573
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