EVpedia provide top 100+ EV markers, selected according to their identification number.
Based on EV proteomes, we defined the identification number of protein A as the number of datasets which contain protein A.
Therefore, proteins with higher identification numbers were more conserved.

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Protein name Gene symbol UniProt accession Identification number
Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2 (AGAP-2) (Centaurin-gamma-1) (Cnt-g1) (GTP-binding and GTPase-activating protein 2) (GGAP2) (Phosphatidylinositol 3-kinase enhancer) (PIKE)AGAP2 CENTG1 KIAA0167Q994903
Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 3AGAP3E9PAL83
Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 3 (AGAP-3) (CRAM-associated GTPase) (CRAG) (Centaurin-gamma-3) (Cnt-g3) (MR1-interacting protein) (MRIP-1)AGAP3 CENTG3Q96P473
Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1 (Centaurin-delta-2) (Cnt-d2)ARAP1 CENTD2 KIAA0782Q96P483
Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 3 (Development and differentiation-enhancing factor-like 1) (Protein up-regulated in liver cancer 1)ASAP3 DDEFL1 UPLC1Q8TDY43
Arginine decarboxylase (ADC) (ARGDC) (EC 4.1.1.19) (ODC-paralogue) (ODC-p) (Ornithine decarboxylase-like protein)ADC KIAA1945 ODCPQ96A703
ARHGAP27 protein (Fragment)ARHGAP27Q8N2Y93
Armadillo repeat-containing protein 1ARMC1 ARCPQ9NVT93
Aryl hydrocarbon receptor nuclear translocator (ARNT protein) (Class E basic helix-loop-helix protein 2) (bHLHe2) (Dioxin receptor, nuclear translocator) (Hypoxia-inducible factor 1-beta) (HIF-1-beta) (HIF1-beta)ARNT BHLHE2P275403
Arylsulfatase D (ASD) (EC 3.1.6.-)ARSDP516893
Asialoglycoprotein receptor 2 (ASGP-R 2) (ASGPR 2) (C-type lectin domain family 4 member H2) (Hepatic lectin H2) (HL-2)ASGR2 CLEC4H2P073073
Aspartate--tRNA ligase, mitochondrial (EC 6.1.1.12) (Aspartyl-tRNA synthetase) (AspRS)DARS2Q6PI483
Aspartoacylase-2 (EC 3.5.1.-) (Acylase III) (Aminoacylase-3) (ACY-3) (Hepatitis C virus core-binding protein 1) (HCBP1) (HCV core-binding protein 1)ACY3 ASPA2Q96HD93
AT-rich interactive domain-containing protein 3A (ARID domain-containing protein 3A) (B-cell regulator of IgH transcription) (Bright) (Dead ringer-like protein 1) (E2F-binding protein 1)ARID3A DRIL1 DRIL3 DRX E2FBP1Q998563
AT-rich interactive domain-containing protein 3B (ARID domain-containing protein 3B) (Bright and dead ringer protein) (Bright-like protein)ARID3B BDP DRIL2Q8IVW63
Ataxin-10 (Brain protein E46 homolog) (Spinocerebellar ataxia type 10 protein)ATXN10 SCA10Q9UBB43
ATP synthase subunit a (F-ATPase protein 6)MT-ATP6 ATP6 ATPASE6 MTATP6P008463
ATP-binding cassette sub-family A member 1 (ATP-binding cassette transporter 1) (ABC-1) (ATP-binding cassette 1) (Cholesterol efflux regulatory protein)ABCA1 ABC1 CERPO954773
ATP-binding cassette sub-family A member 7 (ABCA-SSN) (Autoantigen SS-N) (Macrophage ABC transporter)ABCA7Q8IZY23
ATP-binding cassette sub-family A member 9ABCA9Q8IUA73
ATP-binding cassette sub-family C member 8 (Sulfonylurea receptor 1)ABCC8 HRINS SUR SUR1Q094283
ATP-binding cassette sub-family G member 1 (ATP-binding cassette transporter 8) (White protein homolog)ABCG1 ABC8 WHT1P458443
ATP-dependent (S)-NAD(P)H-hydrate dehydratase (EC 4.2.1.93) (ATP-dependent NAD(P)HX dehydratase) (Carbohydrate kinase domain-containing protein)CARKDQ8IW453
ATP-sensitive inward rectifier potassium channel 12 (Inward rectifier K(+) channel Kir2.2) (IRK-2) (Inward rectifier K(+) channel Kir2.2v) (Potassium channel, inwardly rectifying subfamily J member 12)KCNJ12 IRK2 KCNJN1Q145003
ATPase SWSAP1 (SWIM-type zinc finger 7-associated protein 1) (SWS1-associated protein 1) (ZSWIM7-associated protein 1) (ZSWIM7AP1)SWSAP1 C19orf39Q6NVH73
Autism susceptibility gene 2 proteinAUTS2 KIAA0442Q8WXX73
B box and SPRY domain-containing proteinBSPRYQ5W0U43
B-cell CLL/lymphoma 7 protein family member ABCL7AQ4VC053
B-cell CLL/lymphoma 9 protein (B-cell lymphoma 9 protein) (Bcl-9) (Protein legless homolog)BCL9O005123
B-cell lymphoma/leukemia 10 (B-cell CLL/lymphoma 10) (Bcl-10) (CARD-containing molecule enhancing NF-kappa-B) (CARD-like apoptotic protein) (hCLAP) (CED-3/ICH-1 prodomain homologous E10-like regulator) (CIPER) (Cellular homolog of vCARMEN) (cCARMEN) (Cellular-E10) (c-E10) (Mammalian CARD-containing adapter molecule E10) (mE10)BCL10 CIPER CLAPO959993
B-cell lymphoma/leukemia 11A (BCL-11A) (B-cell CLL/lymphoma 11A) (COUP-TF-interacting protein 1) (Ecotropic viral integration site 9 protein homolog) (EVI-9) (Zinc finger protein 856)BCL11A CTIP1 EVI9 KIAA1809 ZNF856Q9H1653
B-cell translocation gene 1, anti-proliferative (B-cell translocation gene 1, anti-proliferative, isoform CRA_b) (BTG1) (BTG1 protein) (cDNA, FLJ93822, Homo sapiens B-cell translocation gene 1, anti-proliferative(BTG1), mRNA)BTG1 hCG_21188Q6IBC83
B1 bradykinin receptor (B1R) (BK-1 receptor)BDKRB1 BRADYB1P466633
B9 domain-containing protein 2 (MKS1-related protein 2)B9D2 MKSR2Q9BPU93
Band 4.1-like protein 5EPB41L5 KIAA1548Q9HCM43
Bardet-Biedl syndrome 7 protein (BBS2-like protein 1)BBS7 BBS2L1Q8IWZ63
BarH-like 2 homeobox proteinBARHL2Q9NY433
Basic helix-loop-helix domain-containing protein KIAA2018KIAA2018Q68DE33
Basic immunoglobulin-like variable motif-containing proteinBIVMQ86UB23
Bcl-2-modifying factorBMFQ96LC93
Bcl-2-related ovarian killer protein (hBOK) (Bcl-2-like protein 9) (Bcl2-L-9)BOK BCL2L9Q9UMX33
Beta 5-tubulin (Beta-tubulin protein) (Tubulin, beta) (Tubulin, beta, isoform CRA_a)TUBB OK/SW-cl.56 hCG_26016Q5SU163
Beta-1,4-galactosyltransferase 2 (Beta-1,4-GalTase 2) (Beta4Gal-T2) (b4Gal-T2) (EC 2.4.1.-) (UDP-Gal:beta-GlcNAc beta-1,4-galactosyltransferase 2) (UDP-galactose:beta-N-acetylglucosamine beta-1,4-galactosyltransferase 2) [Includes: Lactose synthase A protein (EC 2.4.1.22); N-acetyllactosamine synthase (EC 2.4.1.90) (Nal synthase); Beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase (EC 2.4.1.38); Beta-N-acetylglucosaminyl-glycolipid beta-1,4-galactosyltransferase (EC 2.4.1.-)]B4GALT2O609093
Beta-1,4-galactosyltransferase 4 (Beta-1,4-GalTase 4) (Beta4Gal-T4) (b4Gal-T4) (EC 2.4.1.-) (UDP-Gal:beta-GlcNAc beta-1,4-galactosyltransferase 4) (UDP-galactose:beta-N-acetylglucosamine beta-1,4-galactosyltransferase 4) [Includes: N-acetyllactosamine synthase (EC 2.4.1.90) (Nal synthase); Lactotriaosylceramide beta-1,4-galactosyltransferase (EC 2.4.1.275) (Beta-N-acetylglucosaminyl-glycolipid beta-1,4-galactosyltransferase)]B4GALT4 UNQ552/PRO1109O605133
Beta-1,4-galactosyltransferase 7 (Beta-1,4-GalTase 7) (Beta4Gal-T7) (b4Gal-T7) (EC 2.4.1.-) (UDP-Gal:beta-GlcNAc beta-1,4-galactosyltransferase 7) (UDP-galactose:beta-N-acetylglucosamine beta-1,4-galactosyltransferase 7) [Includes: Xylosylprotein 4-beta-galactosyltransferase (EC 2.4.1.133) (Proteoglycan UDP-galactose:beta-xylose beta1,4-galactosyltransferase I) (UDP-galactose:beta-xylose beta-1,4-galactosyltransferase) (XGPT) (XGalT-1) (Xylosylprotein beta-1,4-galactosyltransferase)]B4GALT7 XGALT1 UNQ748/PRO1478Q9UBV73
Beta-catenin-like protein 1 (Nuclear-associated protein) (NAP) (Testis development protein NYD-SP19)CTNNBL1 C20orf33 PP8304Q8WYA63
Beta-crystallin B2CRYBB2R4UMM23
Beta-defensin 1 (BD-1) (hBD-1) (Defensin, beta 1)DEFB1 BD1 HBD1P600223
Beta-defensin 4A (Beta-defensin 2) (BD-2) (hBD-2) (Defensin, beta 2) (Skin-antimicrobial peptide 1) (SAP1)DEFB4A DEFB102 DEFB2 DEFB4; DEFB4BO152633
Beta-enolase (EC 4.2.1.11) (2-phospho-D-glycerate hydro-lyase) (Enolase 3) (Muscle-specific enolase) (MSE) (Skeletal muscle enolase)ENO3P139293
Beta-hexosaminidase subunit alpha (EC 3.2.1.52) (Beta-N-acetylhexosaminidase subunit alpha) (Hexosaminidase subunit A) (N-acetyl-beta-glucosaminidase subunit alpha)HEXAP068653
Beta-parvin (Affixin)PARVB CGI-56Q9HBI13
Betaine--homocysteine S-methyltransferase 1 (EC 2.1.1.5)BHMTQ930883
Biogenesis of lysosome-related organelles complex 1 subunit 3 (BLOC-1 subunit 3)BLOC1S3 BLOS3Q6QNY03
Biogenesis of lysosome-related organelles complex 1 subunit 5 (BLOC-1 subunit 5) (Protein Muted homolog)BLOC1S5 MUTEDQ8TDH93
Biogenesis of lysosome-related organelles complex 1 subunit 6 (BLOC-1 subunit 6) (Pallid protein homolog) (Pallidin) (Syntaxin 13-interacting protein)BLOC1S6 PA PLDNQ9UL453
Bloom syndrome protein (EC 3.6.4.12) (DNA helicase, RecQ-like type 2) (RecQ2) (RecQ protein-like 3)BLM RECQ2 RECQL3P541323
Bone morphogenetic protein 15 (BMP-15) (Growth/differentiation factor 9B) (GDF-9B)BMP15 GDF9BO959723
Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1 (BAI1-associated protein 2-like protein 1) (Insulin receptor tyrosine kinase substrate)BAIAP2L1 IRTKSQ9UHR43
Branched-chain-amino-acid aminotransferase, cytosolic (BCAT(c)) (EC 2.6.1.42) (Protein ECA39)BCAT1 BCT1 ECA39P546873
Breast cancer type 2 susceptibility protein (Fanconi anemia group D1 protein)BRCA2 FACD FANCD1P515873
Bromodomain and PHD finger-containing protein 3BRPF3 KIAA1286Q9ULD43
BTB/POZ domain-containing protein 10BTBD10Q9BSF83
BTB/POZ domain-containing protein 7BTBD7 KIAA1525Q9P2033
BTB/POZ domain-containing protein KCTD12 (Pfetin) (Predominantly fetal expressed T1 domain)KCTD12 C13orf2 KIAA1778 PFET1Q96CX23
BTB/POZ domain-containing protein KCTD17KCTD17Q8N5Z53
BTB/POZ domain-containing protein KCTD9KCTD9Q7L2733
Butyrophilin subfamily 1 member A1 (BT)BTN1A1 BTNQ134103
C-C chemokine receptor type 1 (C-C CKR-1) (CC-CKR-1) (CCR-1) (CCR1) (HM145) (LD78 receptor) (Macrophage inflammatory protein 1-alpha receptor) (MIP-1alpha-R) (RANTES-R) (CD antigen CD191)CCR1 CMKBR1 CMKR1 SCYAR1P322463
C-C chemokine receptor type 5 (C-C motif chemokine receptor 5 A159A variant) (C-C motif chemokine receptor 5 I124I variant) (C-C motif chemokine receptor 5 I237I variant) (Chemokine (C-C motif) receptor 5, isoform CRA_a) (cDNA FLJ78003, highly similar to Homo sapiens chemokine (C-C motif) receptor 5, mRNA)CCR5 hCG_15321Q38L213
C-C motif chemokine 22 (CC chemokine STCP-1) (MDC(1-69)) (Macrophage-derived chemokine) (Small-inducible cytokine A22) (Stimulated T-cell chemotactic protein 1) [Cleaved into: MDC(3-69); MDC(5-69); MDC(7-69)]CCL22 MDC SCYA22 A-152E5.1O006263
C-myc promoter-binding protein (DENN domain-containing protein 4A)DENND4A IRLB MYCPBPQ7Z4013
C-X-C motif chemokine 6 (Chemokine alpha 3) (CKA-3) (Granulocyte chemotactic protein 2) (GCP-2) (Small-inducible cytokine B6) [Cleaved into: Small-inducible cytokine B6, N-processed variant 1; Small-inducible cytokine B6, N-processed variant 2; Small-inducible cytokine B6, N-processed variant 3]CXCL6 GCP2 SCYB6P801623
C2 domain-containing protein 2-like (Transmembrane protein 24)C2CD2L KIAA0285 TMEM24 DLNB23O145233
C2 domain-containing protein 5 (C2 domain-containing phosphoprotein of 138 kDa)C2CD5 CDP138 KIAA0528Q86YS73
C5a anaphylatoxin chemotactic receptor 2 (Complement component 5a receptor 2) (G-protein coupled receptor 77)C5AR2 C5L2 GPR77Q9P2963
C7 protein (Fragment)C7Q05CI33
CAAX prenyl protease 2 (EC 3.4.22.-) (Farnesylated proteins-converting enzyme 2) (FACE-2) (Prenyl protein-specific endoprotease 2) (RCE1 homolog) (hRCE1)RCE1 FACE2 RCE1A RCE1BQ9Y2563
Cadherin-16 (Kidney-specific cadherin) (Ksp-cadherin)CDH16 UNQ695/PRO1340O753093
Cadherin-23 (Otocadherin)CDH23 KIAA1774 KIAA1812 UNQ1894/PRO4340Q9H2513
Cadherin-like protein 26 (Cadherin-like protein VR20)CDH26Q8IXH83
Calcitonin [Cleaved into: Calcitonin; Katacalcin (Calcitonin carboxyl-terminal peptide) (CCP) (PDN-21)]CALCA CALC1P012583
Calcium binding protein 39, isoform CRA_a (cDNA FLJ78295, highly similar to Homo sapiens calcium binding protein 39 (CAB39), mRNA) (cDNA, FLJ96790, Homo sapiens MO25 protein (MO25), mRNA)CAB39 hCG_34334A8K8L73
Calcium homeostasis modulator protein 2 (Protein FAM26B)CALHM2 FAM26BQ9HA723
Calcium release-activated calcium channel protein 1 (Protein orai-1) (Transmembrane protein 142A)ORAI1 CRACM1 TMEM142AQ96D313
Calcium-activated potassium channel subunit alpha-1 (BK channel) (BKCA alpha) (Calcium-activated potassium channel, subfamily M subunit alpha-1) (K(VCA)alpha) (KCa1.1) (Maxi K channel) (MaxiK) (Slo-alpha) (Slo1) (Slowpoke homolog) (Slo homolog) (hSlo)KCNMA1 KCNMA SLOQ127913
Calcium-binding and coiled-coil domain-containing protein 1 (Calphoglin) (Coiled-coil coactivator protein) (Sarcoma antigen NY-SAR-3)CALCOCO1 KIAA1536 PP13275 UNQ2436/PRO4996Q9P1Z23
Calcium-binding and coiled-coil domain-containing protein 2 (Antigen nuclear dot 52 kDa protein) (Nuclear domain 10 protein NDP52) (Nuclear domain 10 protein 52) (Nuclear dot protein 52)CALCOCO2 NDP52Q131373
Calcium-binding mitochondrial carrier protein SCaMC-1 (Mitochondrial ATP-Mg/Pi carrier protein 1) (Mitochondrial Ca(2+)-dependent solute carrier protein 1) (Small calcium-binding mitochondrial carrier protein 1) (Solute carrier family 25 member 24)SLC25A24 APC1 MCSC1 SCAMC1Q6NUK13
Calcium-binding protein 39 (MO25alpha) (Protein Mo25)CAB39 MO25 CGI-66Q9Y3763
Calcium/calmodulin-dependent protein kinase kinase 2 (CaM-KK 2) (CaM-kinase kinase 2) (CaMKK 2) (EC 2.7.11.17) (Calcium/calmodulin-dependent protein kinase kinase beta) (CaM-KK beta) (CaM-kinase kinase beta) (CaMKK beta)CAMKK2 CAMKKB KIAA0787Q96RR43
Calcium/calmodulin-dependent protein kinase type 1B (EC 2.7.11.17) (CaM kinase I beta) (CaM kinase IB) (CaM-KI beta) (CaMKI-beta) (Pregnancy up-regulated non-ubiquitously-expressed CaM kinase)PNCKQ6P2M83
Calmodulin-like protein 3 (CaM-like protein) (CLP) (Calmodulin-related protein NB-1)CALML3P274823
Calpain-13 (EC 3.4.22.-) (Calcium-activated neutral proteinase 13) (CANP 13)CAPN13Q6MZZ73
Calpain-2 catalytic subunit (EC 3.4.22.53) (Calcium-activated neutral proteinase 2) (CANP 2) (Calpain M-type) (Calpain large polypeptide L2) (Calpain-2 large subunit) (Millimolar-calpain) (M-calpain)CAPN2 CANPL2P176553
Calpain-7 (EC 3.4.22.-) (PalB homolog) (PalBH)CAPN7 PALBHQ9Y6W33
cAMP-dependent protein kinase inhibitor beta (PKI-beta)PKIB PRKACN2Q9C0103
cAMP-dependent protein kinase type I-beta regulatory subunitPRKAR1BP313213
cAMP-specific 3',5'-cyclic phosphodiesterase 4A (EC 3.1.4.17) (DPDE2) (PDE46)PDE4A DPDE2P278153
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (EC 3.1.4.17) (DPDE4) (PDE32)PDE4B DPDE4Q073433
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