EVpedia provide top 100+ EV markers, selected according to their identification number.
Based on EV proteomes, we defined the identification number of protein A as the number of datasets which contain protein A.
Therefore, proteins with higher identification numbers were more conserved.

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Protein name Gene symbol UniProt accession Identification number
cAMP-specific 3',5'-cyclic phosphodiesterase 4D (EC 3.1.4.17) (DPDE3) (PDE43)PDE4D DPDE3Q084993
cAMP-specific 3',5'-cyclic phosphodiesterase 7B (EC 3.1.4.17)PDE7BQ9NP563
CAMPATH-1 antigen (CDw52) (Cambridge pathology 1 antigen) (Epididymal secretory protein E5) (Human epididymis-specific protein 5) (He5) (CD antigen CD52)CD52 CDW52 HE5P313583
Canalicular multispecific organic anion transporter 2 (ATP-binding cassette sub-family C member 3) (Multi-specific organic anion transporter D) (MOAT-D) (Multidrug resistance-associated protein 3)ABCC3 CMOAT2 MLP2 MRP3O154383
CAP-Gly domain-containing linker protein 2 (Cytoplasmic linker protein 115) (CLIP-115) (Cytoplasmic linker protein 2) (Williams-Beuren syndrome chromosomal region 3 protein) (Williams-Beuren syndrome chromosomal region 4 protein)CLIP2 CYLN2 KIAA0291 WBSCR3 WBSCR4 WSCR4Q9UDT63
Carbohydrate sulfotransferase 1 (EC 2.8.2.21) (Galactose/N-acetylglucosamine/N-acetylglucosamine 6-O-sulfotransferase 1) (GST-1) (Keratan sulfate Gal-6 sulfotransferase) (KS6ST) (KSGal6ST) (KSST)CHST1O439163
Carbohydrate sulfotransferase 3 (EC 2.8.2.17) (Chondroitin 6-O-sulfotransferase 1) (C6ST-1) (Chondroitin 6-sulfotransferase) (Galactose/N-acetylglucosamine/N-acetylglucosamine 6-O-sulfotransferase 0) (GST-0)CHST3Q7LGC83
Carbohydrate sulfotransferase 4 (EC 2.8.2.-) (Galactose/N-acetylglucosamine/N-acetylglucosamine 6-O-sulfotransferase 3) (GST-3) (High endothelial cells N-acetylglucosamine 6-O-sulfotransferase) (HEC-GlcNAc6ST) (L-selectin ligand sulfotransferase) (LSST) (N-acetylglucosamine 6-O-sulfotransferase 2) (GlcNAc6ST-2) (Gn6st-2)CHST4Q8NCG53
Carbonic anhydrase 12 (EC 4.2.1.1) (Carbonate dehydratase XII) (Carbonic anhydrase XII) (CA-XII) (Tumor antigen HOM-RCC-3.1.3)CA12O435703
Carcinoembryonic antigen-related cell adhesion molecule 16 (Carcinoembryonic antigen-like 2)CEACAM16 CEAL2Q2WEN93
Carcinoembryonic antigen-related cell adhesion molecule 3 (Carcinoembryonic antigen CGM1) (CD antigen CD66d)CEACAM3 CD66D CGM1P401983
Cardiomyopathy-associated protein 5 (Dystrobrevin-binding protein 2) (Genethonin-3) (Myospryn) (SPRY domain-containing protein 2) (Tripartite motif-containing protein 76)CMYA5 C5orf10 DTNBP2 SPRYD2 TRIM76Q8N3K93
Cardiotrophin-like cytokine factor 1 (B-cell-stimulating factor 3) (BSF-3) (Novel neurotrophin-1) (NNT-1)CLCF1 BSF3 CLC NNT1Q9UBD93
Caspase-10 (CASP-10) (EC 3.4.22.63) (Apoptotic protease Mch-4) (FAS-associated death domain protein interleukin-1B-converting enzyme 2) (FLICE2) (ICE-like apoptotic protease 4) [Cleaved into: Caspase-10 subunit p23/17; Caspase-10 subunit p12]CASP10 MCH4Q928513
Caspase-6 (CASP-6) (EC 3.4.22.59) (Apoptotic protease Mch-2) [Cleaved into: Caspase-6 subunit p18; Caspase-6 subunit p11]CASP6 MCH2P552123
Caspase-7 (CASP-7) (EC 3.4.22.60) (Apoptotic protease Mch-3) (CMH-1) (ICE-like apoptotic protease 3) (ICE-LAP3) [Cleaved into: Caspase-7 subunit p20; Caspase-7 subunit p11]CASP7 MCH3P552103
Cathepsin Z (EC 3.4.18.1) (Cathepsin P) (Cathepsin X)CTSZQ9UBR23
Caveolin (Fragment)0Q59E853
CCDC91 protein (Fragment)CCDC91Q05D283
CD2-associated protein (Adapter protein CMS) (Cas ligand with multiple SH3 domains)CD2APQ9Y5K63
CD48 antigen (B-lymphocyte activation marker BLAST-1) (BCM1 surface antigen) (Leukocyte antigen MEM-102) (SLAM family member 2) (SLAMF2) (Signaling lymphocytic activation molecule 2) (TCT.1) (CD antigen CD48)CD48 BCM1 BLAST1P093263
CD7 antigen (CD7 antigen (P41), isoform CRA_c)CD7 hCG_18659Q29VG33
CD83 antigen (hCD83) (B-cell activation protein) (Cell surface protein HB15) (CD antigen CD83)CD83Q011513
CDC42 effector protein (Rho GTPase binding) 4, isoform CRA_a (cDNA FLJ14479 fis, clone MAMMA1002143, highly similar to Cdc42 effector protein 4 (Binder of Rho GTPases 4)) (cDNA, FLJ92905, Homo sapiens CDC42 effector protein (Rho GTPase binding) 4(CDC42EP4), mRNA)CDC42EP4 hCG_27835B2R6D83
Cdc42 effector protein 2 (Binder of Rho GTPases 1)CDC42EP2 BORG1 CEP2O146133
CDC42 small effector protein 1 (CDC42-binding protein SCIP1) (Small effector of CDC42 protein 1)CDC42SE1 SPEC1Q9NRR83
CDK2-associated and cullin domain-containing protein 1 (Cdk-associated cullin1)CACUL1 C10orf46 CAC1Q86Y373
CDK2-associated protein 2 (DOC-1R protein) (cDNA FLJ10636 fis, clone NT2RP2005675, highly similar to Cyclin-dependent kinase 2-associated protein 2)DOC-1R CDK2AP2 hCG_21052Q6IAV43
cDNA FLJ16300 fis, clone PLACE7000167, highly similar to Retinol dehydrogenase 13 (EC 1.1.1.-)0B3KVA33
cDNA FLJ25990 fis, clone DMC026730Q6ZPD73
cDNA FLJ32005 fis, clone NT2RP7009439, highly similar to HOMEOBOX PROTEIN HOX-A30B3KPN83
cDNA FLJ33103 fis, clone TRACH20009200B3KQ883
cDNA FLJ35217 fis, clone PROST2000284, highly similar to MAP kinase-interactingserine/threonine-protein kinase 2 (EC 2.7.11.1)0B3KS073
cDNA FLJ37578 fis, clone BRCOC2003732, highly similar to Importin-40B3KT383
cDNA FLJ38437 fis, clone FEBRA2016572, highly similar to Membralin0B3KTL03
cDNA FLJ41163 fis, clone BRACE2039734 (Fragment)0Q6ZWF93
cDNA FLJ46318 fis, clone TESTI4041984, highly similar to Homo sapiens latent transforming growth factor beta binding protein 4 (LTBP4), mRNA0B3KXY63
cDNA FLJ52313, highly similar to McKusick-Kaufman/Bardet-Biedl syndromes putative chaperonin0B7Z3W93
cDNA FLJ53015, highly similar to Homo sapiens GTP binding protein 3 (GTPBP3), transcript variant IV, mRNA0B7Z5633
cDNA FLJ53340, highly similar to Homo sapiens progestin and adipoQ receptor family member VI (PAQR6), transcript variant 1, mRNA0B4DJ423
cDNA FLJ57817, highly similar to Homeodomain-interacting protein kinase 1 (EC 2.7.11.1)0B4DZ333
cDNA FLJ57889, highly similar to Cytochrome b-245 light chain0B4DT463
cDNA FLJ61569, highly similar to 5-hydroxytryptamine 3 receptor0B4E3983
cDNA FLJ61589 (Fragment)0B4DGV13
cDNA FLJ615990B4E0Y13
cDNA FLJ751850A8K3D03
cDNA FLJ76392, highly similar to Homo sapiens mitochondrial ribosomal protein L43 (MRPL43), transcript variant 1, mRNA0A8K4V43
cDNA FLJ76851, highly similar to Homo sapiens pre-B-cell leukemia transcription factor 1 (PBX1), mRNA0A8K5V03
cDNA FLJ77391, highly similar to Homo sapiens EH-domain containing 4 (EHD4), mRNA0A8K9B93
cDNA FLJ777880A8K7U33
cDNA FLJ78248, highly similar to Homo sapiens TBC1 domain family, member 3C, mRNA0A8K8E33
cDNA FLJ78551, highly similar to Homo sapiens solute carrier family 37 (glycerol-6-phosphate transporter), member 4 (SLC37A4), mRNA0A8K0S73
cDNA FLJ90454 fis, clone NT2RP3001560, highly similar to Cleft lip and palate transmembrane protein 10B3KQH23
cDNA, FLJ93285, highly similar to Homo sapiens cell division cycle associated 3 (CDCA3), mRNA0B2R7493
cDNA, FLJ94149, highly similar to Homo sapiens CD209 antigen (CD209), mRNA0B2R9073
cDNA, FLJ95582, highly similar to Homo sapiens breast cancer anti-estrogen resistance 1 (BCAR1),mRNA0B2RBL93
cDNA, FLJ95785, highly similar to Homo sapiens excision repair cross-complementing rodent repairdeficiency, complementation group 1 (includes overlapping antisensesequence) (ERCC1), mRNA0B2RC013
CDP-diacylglycerol--inositol 3-phosphatidyltransferase (Phosphatidylinositol synthase), isoform CRA_a (cDNA FLJ40372 fis, clone TESTI2034940, highly similar to CDP-diacylglycerol--inositol3-phosphatidyltransferase (EC 2.7.8.11)) (cDNA FLJ77674, highly similar to Homo sapiens CDP-diacylglycerol--inositol 3-phosphatidyltransferase (phosphatidylinositol synthase) (CDIPT), transcript variant 1, mRNA)CDIPT hCG_21626A8K3L73
Cell division control protein 6 homolog (CDC6-related protein) (Cdc18-related protein) (HsCdc18) (p62(cdc6)) (HsCDC6)CDC6 CDC18LQ997413
Cell growth-inhibiting gene 8 (Inhibitor of DNA binding 2, dominant negative helix-loop-helix protein, isoform CRA_a) (Putative uncharacterized protein ID2) (cDNA, FLJ92261, highly similar to Homo sapiens inhibitor of DNA binding 2, dominant negative helix-loop-helix protein (ID2), mRNA)ID2 GIG8 hCG_1784377Q53T663
Cell growth-regulating nucleolar proteinLYAR PNAS-5Q9NX583
Cell proliferation-inducing protein 47 (HCG39985, isoform CRA_a) (cDNA, FLJ94101, Homo sapiens ATP synthase, H+ transporting, mitochondrial F0complex, subunit b, isoform 1 (ATP5F1), mRNA)hCG_39985Q08ET03
Cellular tumor antigen p53 (Antigen NY-CO-13) (Phosphoprotein p53) (Tumor suppressor p53)TP53 P53P046373
Cementoblastoma-derived protein 1 (Cementum protein 1) (Cementum protein 23) (CP-23)CEMP1 CP23Q6PRD73
Centlein (Centrosomal protein)CNTLN C9orf101 C9orf39Q9NXG03
Centromere protein T (CENP-T) (Interphase centromere complex protein 22)CENPT C16orf56 ICEN22Q96BT33
Centrosomal protein kizuna (Polo-like kinase 1 substrate 1)PLK1S1 C20orf19 KIZ NCRNA00153 HT013Q2M2Z53
Centrosomal protein of 68 kDa (Cep68)CEP68 KIAA0582Q76N323
Centrosomal protein of 78 kDa (Cep78)CEP78 C9orf81Q5JTW23
Centrosomal protein of 89 kDa (Cep89) (Coiled-coil domain-containing protein 123)CEP89 CCDC123Q96ST83
Centrosomal protein of 97 kDa (Cep97) (Leucine-rich repeat and IQ domain-containing protein 2)CEP97 LRRIQ2Q8IW353
Ceramide synthase 2 (CerS2) (LAG1 longevity assurance homolog 2) (SP260) (Tumor metastasis-suppressor gene 1 protein)CERS2 LASS2 TMSG1Q96G233
Cerebral cavernous malformations 2 protein-like (CCM2-like)CCM2L C20orf160Q9NUG43
cGMP-dependent protein kinase 1 (cGK 1) (cGK1) (EC 2.7.11.12) (cGMP-dependent protein kinase I) (cGKI)PRKG1 PRKG1B PRKGR1A PRKGR1BQ139763
Chitinase domain-containing protein 1 (Stabilin-1-interacting chitinase-like protein) (SI-CLP)CHID1 GL008 PSEC0104 SB139Q9BWS93
Chloride transport protein 6 (Chloride channel protein 6) (ClC-6)CLCN6 KIAA0046P517973
Choline/ethanolamine kinase (Choline kinase beta) (CK) (CKB) (EC 2.7.1.32) (Choline kinase-like protein) (Ethanolamine kinase) (EK) (EC 2.7.1.82) (Ethanolamine kinase beta) (EKB) (choline/ethanolamine kinase beta) (CKEKB)CHKB CHETK CHKLQ9Y2593
Chondrosarcoma-associated protein 2CSA2Q9UK433
ChordinCHRD UNQ217/PRO243Q9H2X03
Chordin-like protein 1 (Neuralin-1) (Neurogenesin-1) (Ventroptin)CHRDL1 NRLN1Q9BU403
Chorionic somatomammotropin hormone-like 1 (Chorionic somatomammotropin-like) (Lactogen-like)CSHL1 CSHP1 CSLQ144063
Chromatin assembly factor 1 subunit B (CAF-1 subunit B) (Chromatin assembly factor I p60 subunit) (CAF-I 60 kDa subunit) (CAF-I p60) (M-phase phosphoprotein 7)CHAF1B CAF1A CAF1P60 MPHOSPH7 MPP7Q131123
Chromobox protein homolog 1 (HP1Hsbeta) (Heterochromatin protein 1 homolog beta) (HP1 beta) (Heterochromatin protein p25) (M31) (Modifier 1 protein) (p25beta)CBX1 CBXP839163
Chromobox protein homolog 8 (Polycomb 3 homolog) (Pc3) (hPc3) (Rectachrome 1)CBX8 PC3 RC1Q9HC523
Chromodomain-helicase-DNA-binding protein 1 (CHD-1) (EC 3.6.4.12) (ATP-dependent helicase CHD1)CHD1O146463
Chromodomain-helicase-DNA-binding protein 3 (CHD-3) (EC 3.6.4.12) (ATP-dependent helicase CHD3) (Mi-2 autoantigen 240 kDa protein) (Mi2-alpha) (Zinc finger helicase) (hZFH)CHD3Q128733
Chromosome transmission fidelity protein 8 homolog (hCTF8)CHTF8 CTF8P0CG133
Chymotrypsin-like elastase family member 3B (EC 3.4.21.70) (Elastase IIIB) (Elastase-3B) (Protease E)CELA3B ELA3BP088613
CIB2 protein (Calcium and integrin binding family member 2, isoform CRA_a) (Calcium and integrin-binding family member 2)CIB2 hCG_38933Q05BT63
Ciprofibrate bound protein p240 isoform PRIC320-20Q461N23
Circadian locomoter output cycles protein kaput (hCLOCK) (EC 2.3.1.48) (Class E basic helix-loop-helix protein 8) (bHLHe8)CLOCK BHLHE8 KIAA0334O155163
Clarin-1 (Usher syndrome type-3 protein)CLRN1 USH3AP584183
Class A basic helix-loop-helix protein 9 (bHLHa9) (Class F basic helix-loop-helix factor 42) (bHLHf42)BHLHA9 BHLHF42Q7RTU43
Class E basic helix-loop-helix protein 23 (bHLHe23) (Class B basic helix-loop-helix protein 4) (bHLHb4)BHLHE23 BHLHB4Q8NDY63
Class E basic helix-loop-helix protein 41 (bHLHe41) (Class B basic helix-loop-helix protein 3) (bHLHb3) (Differentially expressed in chondrocytes protein 2) (hDEC2) (Enhancer-of-split and hairy-related protein 1) (SHARP-1)BHLHE41 BHLHB3 DEC2 SHARP1Q9C0J93
Claudin-19CLDN19Q8N6F13
Claudin-9CLDN9O954843
Cleavage and polyadenylation specificity factor subunit 2 (Cleavage and polyadenylation specificity factor 100 kDa subunit) (CPSF 100 kDa subunit)CPSF2 CPSF100 KIAA1367Q9P2I03
Cleft lip and palate transmembrane protein 1-like protein (CLPTM1-like protein) (Cisplatin resistance-related protein 9) (CRR9p)CLPTM1L CRR9Q96KA53
CLIP-associating protein 1 (Cytoplasmic linker-associated protein 1) (Multiple asters homolog 1) (Protein Orbit homolog 1) (hOrbit1)CLASP1 KIAA0622 MAST1Q7Z4603
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