EVpedia provide top 100+ EV markers, selected according to their identification number.
Based on EV proteomes, we defined the identification number of protein A as the number of datasets which contain protein A.
Therefore, proteins with higher identification numbers were more conserved.

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Protein name Gene symbol UniProt accession Identification number
CLIP-associating protein 2 (Cytoplasmic linker-associated protein 2) (Protein Orbit homolog 2) (hOrbit2)CLASP2 KIAA0627O751223
CMP-N-acetylneuraminate-poly-alpha-2,8-sialyltransferase (EC 2.4.99.-) (Alpha-2,8-sialyltransferase 8D) (Polysialyltransferase-1) (Sialyltransferase 8D) (SIAT8-D) (Sialyltransferase St8Sia IV) (ST8SiaIV)ST8SIA4 PST PST1 SIAT8DQ921873
CMRF35-like molecule 9 (CLM-9) (CD300 antigen-like family member G) (Triggering receptor expressed on myeloid cells 4) (TREM-4) (CD antigen CD300g)CD300LG CLM9 TREM4 UNQ422/PRO846Q6UXG33
Coagulation factor VII (EC 3.4.21.21) (Proconvertin) (Serum prothrombin conversion accelerator) (SPCA) (Eptacog alfa) [Cleaved into: Factor VII light chain; Factor VII heavy chain]F7P087093
Coagulation factor VIII (Antihemophilic factor) (AHF) (Procoagulant component) [Cleaved into: Factor VIIIa heavy chain, 200 kDa isoform; Factor VIIIa heavy chain, 92 kDa isoform; Factor VIII B chain; Factor VIIIa light chain]F8 F8CP004513
Coagulation factor XI (FXI) (EC 3.4.21.27) (Plasma thromboplastin antecedent) (PTA) [Cleaved into: Coagulation factor XIa heavy chain; Coagulation factor XIa light chain]F11P039513
Cob(I)yrinic acid a,c-diamide adenosyltransferase, mitochondrial (EC 2.5.1.17) (Cob(I)alamin adenosyltransferase) (Methylmalonic aciduria type B protein)MMABQ96EY83
Coiled-coil and C2 domain-containing protein 1A (Akt kinase-interacting protein 1) (Five prime repressor element under dual repression-binding protein 1) (FRE under dual repression-binding protein 1) (Freud-1) (Putative NF-kappa-B-activating protein 023N)CC2D1A AKI1Q6P1N03
Coiled-coil and C2 domain-containing protein 1B (Five prime repressor element under dual repression-binding protein 2) (FRE under dual repression-binding protein 2) (Freud-2)CC2D1B KIAA1836Q5T0F93
Coiled-coil domain-containing protein 105CCDC105Q8IYK23
Coiled-coil domain-containing protein 136 (Nasopharyngeal carcinoma-associated gene 6 protein)CCDC136 KIAA1793 NAG6Q96JN23
Coiled-coil domain-containing protein 151CCDC151A5D8V73
Coiled-coil domain-containing protein 153CCDC153Q494R43
Coiled-coil domain-containing protein 176CCDC176 C14orf45Q8ND073
Coiled-coil-helix-coiled-coil-helix domain-containing protein 6, mitochondrial (Coiled coil helix cristae morphology protein 1)CHCHD6 CHCM1Q9BRQ63
Coiled-coil-helix-coiled-coil-helix domain-containing protein 7CHCHD7Q9BUK03
Collagen alpha-1(V) chainCOL5A1P209083
Collagen alpha-1(XVI) chainCOL16A1 FP1572Q070923
Collagen alpha-1(XX) chainCOL20A1 KIAA1510Q9P2183
Collagen alpha-1(XXV) chain (Alzheimer disease amyloid-associated protein) (AMY) (CLAC-P) [Cleaved into: Collagen-like Alzheimer amyloid plaque component (CLAC)]COL25A1Q9BXS03
Collagen alpha-2(VI) chainCOL6A2P121103
Collagen alpha-5(IV) chainCOL4A5P294003
Collectin-11 (Collectin kidney protein 1) (CL-K1)COLEC11 UNQ596/PRO1182Q9BWP83
Complement C1q subcomponent subunit CC1QC C1QGP027473
Complement C1q tumor necrosis factor-related protein 4C1QTNF4 CTRP4Q9BXJ33
Complement C1q tumor necrosis factor-related protein 5C1QTNF5 CTRP5 UNQ303/PRO344Q9BXJ03
Complement component 2, isoform CRA_b (cDNA, FLJ92956, Homo sapiens complement component 2 (C2), mRNA)C2 hCG_43694Q5JP693
Complement component C1q receptor (C1q/MBL/SPA receptor) (C1qR) (C1qR(p)) (C1qRp) (CDw93) (Complement component 1 q subcomponent receptor 1) (Matrix-remodeling-associated protein 4) (CD antigen CD93)CD93 C1QR1 MXRA4Q9NPY33
Complement component C8 beta chain (Complement component 8 subunit beta)C8BP073583
Complement factor H (H factor 1)CFH HF HF1 HF2P086033
Complex III assembly factor LYRM7 (LYR motif-containing protein 7)LYRM7 C5orf31 MZM1LQ5U5X03
Condensin-2 complex subunit G2 (Chromosome-associated protein G2) (CAP-G2) (hCAP-G2) (Leucine zipper protein 5) (Non-SMC condensin II complex subunit G2)NCAPG2 LUZP5Q86XI23
Connector enhancer of kinase suppressor of ras 3 (Connector enhancer of KSR 3) (CNK homolog protein 3) (CNK3) (CNKSR family member 3) (Maguin-like protein)CNKSR3 MAGI1Q6P9H43
Conserved oligomeric Golgi complex subunit 3 (COG complex subunit 3) (Component of oligomeric Golgi complex 3) (Vesicle-docking protein SEC34 homolog) (p94)COG3 SEC34Q96JB23
COP9 signalosome complex subunit 4 (SGN4) (Signalosome subunit 4) (JAB1-containing signalosome subunit 4)COPS4 CSN4Q9BT783
Copine-2 (Copine II)CPNE2Q96FN43
Copine-5 (Copine V)CPNE5 KIAA1599Q9HCH33
Copper homeostasis protein cutC homologCUTC CGI-32Q9NTM93
Coproporphyrinogen-III oxidase, mitochondrial (COX) (Coprogen oxidase) (Coproporphyrinogenase) (EC 1.3.3.3)CPOX CPO CPXP365513
Core-binding factor subunit beta (CBF-beta) (Polyomavirus enhancer-binding protein 2 beta subunit) (PEA2-beta) (PEBP2-beta) (SL3-3 enhancer factor 1 subunit beta) (SL3/AKV core-binding factor beta subunit)CBFBQ139513
Corneodesmosin (S protein)CDSNQ155173
Coronin-1A (Coronin-like protein A) (Clipin-A) (Coronin-like protein p57) (Tryptophan aspartate-containing coat protein) (TACO)CORO1A CORO1P311463
Coronin-7 (Crn7) (70 kDa WD repeat tumor rejection antigen homolog)CORO7P577373
Corticosteroid 11-beta-dehydrogenase isozyme 2 (EC 1.1.1.-) (11-beta-hydroxysteroid dehydrogenase type 2) (11-DH2) (11-beta-HSD2) (11-beta-hydroxysteroid dehydrogenase type II) (-HSD11 type II) (NAD-dependent 11-beta-hydroxysteroid dehydrogenase) (11-beta-HSD)HSD11B2 HSD11KP803653
Corticotropin-releasing factor receptor 1 (CRF-R-1) (CRF-R1) (CRFR-1) (Corticotropin-releasing hormone receptor 1) (CRH-R-1) (CRH-R1)CRHR1 CRFR CRFR1 CRHRP349983
COX assembly mitochondrial protein homolog (Cmc1p)CMC1 C3orf68Q7Z7K03
Craniofacial development protein 1 (Bucentaur)CFDP1 BCNTQ9UEE93
Crm, cramped-like (Drosophila)CRAMP1LB2RNX83
CST complex subunit CTC1 (Conserved telomere maintenance component 1) (HBV DNAPTP1-transactivated protein B)CTC1 C17orf68Q2NKJ33
CST complex subunit STN1 (Oligonucleotide/oligosaccharide-binding fold-containing protein 1) (Suppressor of cdc thirteen homolog)OBFC1 STN1Q9H6683
CTP synthase 1 (EC 6.3.4.2) (CTP synthetase 1) (UTP--ammonia ligase 1)CTPS1 CTPSP178123
Cullin-1 (CUL-1)CUL1Q136163
Cullin-3 (CUL-3)CUL3 KIAA0617Q136183
Cullin-7 (CUL-7)CUL7 KIAA0076Q149993
CWF19-like protein 2CWF19L2Q2TBE03
Cyclic AMP-responsive element-binding protein 3-like protein 1 (cAMP-responsive element-binding protein 3-like protein 1) (Old astrocyte specifically-induced substance) (OASIS) [Cleaved into: Processed cyclic AMP-responsive element-binding protein 3-like protein 1]CREB3L1 OASIS PSEC0238Q96BA83
Cyclic AMP-responsive element-binding protein 3-like protein 2 (cAMP-responsive element-binding protein 3-like protein 2) (BBF2 human homolog on chromosome 7) [Cleaved into: Processed cyclic AMP-responsive element-binding protein 3-like protein 2]CREB3L2 BBF2H7Q70SY13
Cyclic GMP-AMP synthase (cGAMP synthase) (cGAS) (h-cGAS) (EC 2.7.7.86) (Mab-21 domain-containing protein 1)MB21D1 C6orf150Q8N8843
Cyclin-dependent kinase 12 (EC 2.7.11.22) (EC 2.7.11.23) (Cdc2-related kinase, arginine/serine-rich) (CrkRS) (Cell division cycle 2-related protein kinase 7) (CDC2-related protein kinase 7) (Cell division protein kinase 12) (hCDK12)CDK12 CRK7 CRKRS KIAA0904Q9NYV43
Cyclin-dependent kinase 3 (EC 2.7.11.22) (Cell division protein kinase 3)CDK3 CDKN3Q005263
Cyclin-dependent kinase 4 inhibitor B (Multiple tumor suppressor 2) (MTS-2) (p14-INK4b) (p15-INK4b) (p15INK4B)CDKN2B MTS2P427723
Cyclin-dependent kinase 8 (EC 2.7.11.22) (EC 2.7.11.23) (Cell division protein kinase 8) (Mediator complex subunit CDK8) (Mediator of RNA polymerase II transcription subunit CDK8) (Protein kinase K35)CDK8P493363
Cyclin-dependent kinase inhibitor 1C (Cyclin-dependent kinase inhibitor p57) (p57Kip2)CDKN1C KIP2P499183
Cyclin-G2CCNG2Q165893
Cyclin-T1 (CycT1) (Cyclin-T)CCNT1O605633
Cystathionine gamma-lyase (EC 4.4.1.1) (Cysteine-protein sulfhydrase) (Gamma-cystathionase)CTHP329293
Cystatin-F (Cystatin-7) (Cystatin-like metastasis-associated protein) (CMAP) (Leukocystatin)CST7O760963
Cystatin-M (Cystatin-6) (Cystatin-E)CST6Q158283
Cysteine and glycine-rich protein 1 (Cysteine and glycine-rich protein 1, isoform CRA_b) (cDNA FLJ75177, highly similar to Homo sapiens cysteine and glycine-rich protein 1 (CSRP1), mRNA)CSRP1 hCG_17679Q5U0J23
Cysteine and histidine-rich domain-containing protein 1 (CHORD domain-containing protein 1) (CHORD-containing protein 1) (CHP-1) (Protein morgana)CHORDC1 CHP1Q9UHD13
Cysteine-rich with EGF-like domain protein 2CRELD2 UNQ185/PRO211Q6UXH13
Cystic fibrosis transmembrane conductance regulator (CFTR) (ATP-binding cassette sub-family C member 7) (Channel conductance-controlling ATPase) (EC 3.6.3.49) (cAMP-dependent chloride channel)CFTR ABCC7P135693
Cystin-1 (Cilia-associated protein)CYS1Q717R93
Cytochrome b5 type B (Cytochrome b5 type B (Outer mitochondrial membrane), isoform CRA_a)CYB5B hCG_28205J3KNF83
Cytochrome b561 domain-containing protein 2 (Putative tumor suppressor protein 101F6)CYB561D2 101F6 LUCA12.2O145693
Cytochrome cCYCSG4XXL93
Cytochrome c oxidase assembly protein COX19 (hCOX19)COX19Q49B963
Cytochrome P450 19A1 (EC 1.14.14.1) (Aromatase) (CYPXIX) (Cytochrome P-450AROM) (Estrogen synthase)CYP19A1 ARO1 CYAR CYP19P115113
Cytochrome P450 26A1 (EC 1.14.-.-) (Cytochrome P450 retinoic acid-inactivating 1) (Cytochrome P450RAI) (hP450RAI) (Retinoic acid 4-hydroxylase) (Retinoic acid-metabolizing cytochrome)CYP26A1 CYP26 P450RAI1O431743
Cytochrome P450 26B1 (EC 1.14.-.-) (Cytochrome P450 26A2) (Cytochrome P450 retinoic acid-inactivating 2) (Cytochrome P450RAI-2) (Retinoic acid-metabolizing cytochrome)CYP26B1 CYP26A2 P450RAI2Q9NR633
Cytochrome P450 2A6 (EC 1.14.13.-) (1,4-cineole 2-exo-monooxygenase) (CYPIIA6) (Coumarin 7-hydroxylase) (Cytochrome P450 IIA3) (Cytochrome P450(I))CYP2A6 CYP2A3P115093
Cytochrome P450 2A7 (EC 1.14.14.1) (CYPIIA7) (Cytochrome P450 IIA4)CYP2A7P208533
Cytochrome P450 2E1 (EC 1.14.13.-) (4-nitrophenol 2-hydroxylase) (EC 1.14.13.n7) (CYPIIE1) (Cytochrome P450-J) [Cleaved into: Cytochrome P450 2E1, N-terminally processed]CYP2E1 CYP2EP051813
Cytochrome P450 2S1 (EC 1.14.14.1) (CYPIIS1)CYP2S1 UNQ891/PRO1906Q96SQ93
Cytochrome P450 2U1 (EC 1.14.14.1)CYP2U1Q7Z4493
Cytohesin-1 (PH, SEC7 and coiled-coil domain-containing protein 1) (SEC7 homolog B2-1)CYTH1 D17S811E PSCD1Q154383
Cytokine receptor-like factor 3 (Cytokine receptor-like molecule 9) (CREME-9) (Cytokine receptor-related protein 4) (Type I cytokine receptor-like factor p48)CRLF3 CREME9 CRLM9 CYTOR4 P48Q8IUI83
Cytoplasmic dynein 1 intermediate chain 2 (Cytoplasmic dynein intermediate chain 2) (Dynein intermediate chain 2, cytosolic) (DH IC-2)DYNC1I2 DNCI2 DNCIC2Q134093
Cytoplasmic polyadenylation element-binding protein 4 (CPE-BP4) (CPE-binding protein 4) (hCPEB-4)CPEB4 KIAA1673Q17RY03
Cytoskeleton-associated protein 2-likeCKAP2LQ8IYA63
Cytosolic 5'-nucleotidase 3A (EC 3.1.3.5) (Cytosolic 5'-nucleotidase 3) (Cytosolic 5'-nucleotidase III) (cN-III) (Pyrimidine 5'-nucleotidase 1) (P5'N-1) (P5N-1) (PN-I) (Uridine 5'-monophosphate hydrolase 1) (p36)NT5C3A NT5C3 P5N1 UMPH1 HSPC233Q9H0P03
Cytosolic Fe-S cluster assembly factor NUBP2 (Nucleotide-binding protein 2) (NBP 2)NUBP2Q9Y5Y23
D(2) dopamine receptor (Dopamine D2 receptor)DRD2P144163
D(3) dopamine receptorDRD3E9PCM43
D-amino-acid oxidase (DAAO) (DAMOX) (DAO) (EC 1.4.3.3)DAO DAMOXP149203
Dapper homolog 1 (hDPR1) (Dapper antagonist of catenin 1) (Hepatocellular carcinoma novel gene 3 protein)DACT1 DPR1 HNG3Q9NYF03
DCC-interacting protein 13-alpha (Dip13-alpha) (Adapter protein containing PH domain, PTB domain and leucine zipper motif 1)APPL1 APPL DIP13A KIAA1428Q9UKG13
DDB1- and CUL4-associated factor 11 (WD repeat-containing protein 23)DCAF11 WDR23 GL014 PRO2389Q8TEB13
DDB1- and CUL4-associated factor 12 (Centrosome-related protein TCC52) (Testis cancer centrosome-related protein) (WD repeat-containing protein 40A)DCAF12 KIAA1892 TCC52 WDR40AQ5T6F03
DDRGK domain-containing protein 1DDRGK1 C20orf116Q96HY63
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