EVpedia provide top 100+ EV markers, selected according to their identification number.
Based on EV proteomes, we defined the identification number of protein A as the number of datasets which contain protein A.
Therefore, proteins with higher identification numbers were more conserved.

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Protein name Gene symbol UniProt accession Identification number
Dead end protein homolog 1 (RNA-binding motif, single-stranded-interacting protein 4)DND1 RBMS4Q8IYX43
Death-inducer obliterator 1 (DIO-1) (hDido1) (Death-associated transcription factor 1) (DATF-1)DIDO1 C20orf158 DATF1 KIAA0333Q9BTC03
Dedicator of cytokinesis protein 7DOCK7 KIAA1771Q96N673
Defender against cell death 1 variant (Fragment)0Q53G023
Dehydrogenase/reductase SDR family member 13 (EC 1.1.-.-)DHRS13 UNQ419/PRO853Q6UX073
DENN domain-containing protein 2ADENND2A KIAA1277Q9ULE33
Dermatan-sulfate epimerase-like protein (EC 5.1.-.-)DSEL C18orf4 NCAG1Q8IZU83
Desert hedgehog protein (DHH) (HHG-3) [Cleaved into: Desert hedgehog protein N-product; Desert hedgehog protein C-product]DHHO433233
Diacylglycerol kinase alpha (DAG kinase alpha) (EC 2.7.1.107) (80 kDa diacylglycerol kinase) (Diglyceride kinase alpha) (DGK-alpha)DGKA DAGK DAGK1P237433
Diacylglycerol O-acyltransferase 2 (EC 2.3.1.20) (Acyl-CoA retinol O-fatty-acyltransferase) (ARAT) (Retinol O-fatty-acyltransferase) (EC 2.3.1.76) (Diglyceride acyltransferase 2)DGAT2 HMFN1045 UNQ738/PRO1433Q96PD73
Diamine acetyltransferase 2 (EC 2.3.1.57) (Polyamine N-acetyltransferase 2) (Spermidine/spermine N(1)-acetyltransferase 2) (Thialysine N-epsilon-acetyltransferase)SAT2 SSAT2Q96F103
Dihydrolipoamide S-acetyltransferase (Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex mitochondrial) (cDNA FLJ32737 fis, clone TESTI2001269, highly similar to Homo sapiens dihydrolipoamide S-acetyltransferase, mRNA)DLATQ86YI53
Dihydropyrimidinase-like 3DPYSL3Q8IXW63
Dimethyladenosine transferase 2, mitochondrial (EC 2.1.1.-) (Hepatitis C virus NS5A-transactivated protein 5) (HCV NS5A-transactivated protein 5) (Mitochondrial 12S rRNA dimethylase 2) (Mitochondrial transcription factor B2) (h-mtTFB) (h-mtTFB2) (hTFB2M) (mtTFB2) (S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase 2)TFB2M NS5ATP5Q9H5Q43
Dimethylaniline monooxygenase [N-oxide-forming] 2 (EC 1.14.13.8) (Dimethylaniline oxidase 2) (FMO 1B1) (Pulmonary flavin-containing monooxygenase 2) (FMO 2)FMO2Q995183
Dimethylarginine dimethylaminohydrolase 1, isoform CRA_b (cDNA, FLJ92778, Homo sapiens dimethylarginine dimethylaminohydrolase 1 (DDAH1), mRNA)DDAH1 hCG_2040048B1AKK23
Dipeptidase 3 (EC 3.4.13.19)DPEP3 UNQ834/PRO1772Q9H4B83
Dipeptidyl peptidase 9 (DP9) (EC 3.4.14.5) (Dipeptidyl peptidase IV-related protein 2) (DPRP-2) (Dipeptidyl peptidase IX) (DPP IX) (Dipeptidyl peptidase-like protein 9) (DPLP9)DPP9 DPRP2Q86TI23
Diphthine synthase (EC 2.1.1.98)DPH5 hCG_32849B3KWP13
Diphthine--ammonia ligase (EC 6.3.1.14) (ATP-binding domain-containing protein 4) (Diphthamide synthase) (Diphthamide synthetase) (Protein DPH6 homolog)DPH6 ATPBD4Q7L8W63
Disintegrin and metalloproteinase domain-containing protein 11 (ADAM 11) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein) (MDC)ADAM11 MDCO750783
Disks large homolog 1 (Synapse-associated protein 97) (SAP-97) (SAP97) (hDlg)DLG1Q129593
Disks large homolog 2 (Channel-associated protein of synapse-110) (Chapsyn-110) (Postsynaptic density protein PSD-93)DLG2Q157003
DMA protein (HLA-DMA protein) (Major histocompatibility complex, class II, DM alpha) (Major histocompatibility complex, class II, DM alpha, isoform CRA_c) (cDNA FLJ75740, highly similar to Homo sapiens major histocompatibility complex, class II, DM alpha (HLA-DMA), mRNA)DMA HLA-DMA hCG_2001572Q316043
DNA dC->dU-editing enzyme APOBEC-3F (EC 3.5.4.-) (Apolipoprotein B mRNA-editing enzyme catalytic polypeptide-like 3F) (A3F)APOBEC3FQ8IUX43
DNA dC->dU-editing enzyme APOBEC-3G (EC 3.5.4.-) (APOBEC-related cytidine deaminase) (APOBEC-related protein) (ARCD) (APOBEC-related protein 9) (ARP-9) (CEM-15) (CEM15) (Deoxycytidine deaminase) (A3G)APOBEC3G MDS019Q9HC163
DNA helicase B (hDHB) (EC 3.6.4.12)HELBQ8NG083
DNA methyltransferase 1-associated protein 1 (DNMAP1) (DNMT1-associated protein 1)DMAP1 KIAA1425Q9NPF53
DNA mismatch repair protein Mlh1 (MutL protein homolog 1)MLH1 COCA2P406923
DNA polymerase (EC 2.7.7.7) (Fragment)0Q59FA03
DNA polymerase epsilon subunit 2 (EC 2.7.7.7) (DNA polymerase II subunit 2) (DNA polymerase epsilon subunit B)POLE2 DPE2P562823
DNA polymerase sigma (EC 2.7.7.7) (DNA polymerase kappa) (LAK-1) (PAP-associated domain-containing protein 7) (Terminal uridylyltransferase 5) (TUTase 5) (Topoisomerase-related function protein 4-1) (TRF4-1)PAPD7 POLS TRF4Q5XG873
DNA polymerase subunit gamma-1 (EC 2.7.7.7) (Mitochondrial DNA polymerase catalytic subunit) (PolG-alpha)POLG MDP1 POLG1 POLGAP540983
DNA polymerase subunit gamma-1 (Polymerase (DNA directed), gamma, isoform CRA_a)POLG hCG_28647E5KNU53
DNA repair protein XRCC1 (X-ray repair cross-complementing protein 1)XRCC1P188873
DNA replication complex GINS protein PSF1 (GINS complex subunit 1)GINS1 KIAA0186 PSF1Q146913
DNA replication factor Cdt1 (Double parked homolog) (DUP)CDT1Q9H2113
DNA replication licensing factor MCM5 (EC 3.6.4.12) (CDC46 homolog) (P1-CDC46)MCM5 CDC46P339923
DNA-3-methyladenine glycosylase (N-methylpurine-DNA glycosylase, isoform CRA_c)MPG hCG_22412Q1W6H13
DNA-binding protein inhibitor ID-1 (Class B basic helix-loop-helix protein 24) (bHLHb24) (Inhibitor of DNA binding 1)ID1 BHLHB24 IDP411343
DNA-binding protein inhibitor ID-4 (Class B basic helix-loop-helix protein 27) (bHLHb27) (Inhibitor of DNA binding 4)ID4 BHLHB27P479283
DNA-binding protein SATB1 (Special AT-rich sequence-binding protein 1)SATB1Q018263
DNA-directed RNA polymerase I subunit RPA12 (Zinc ribbon domain-containing protein 1)ZNRD1 RPA12Q9P1U03
DNA-directed RNA polymerase II subunit RPB11-b1POLR2J2F6W0093
DNA-directed RNA polymerase III subunit RPC7 (RNA polymerase III subunit C7) (DNA-directed RNA polymerase III subunit G) (RNA polymerase III 32 kDa subunit) (RPC32)POLR3GO153183
DNA-directed RNA polymerase III subunit RPC7-like (RNA polymerase III subunit C7-like) (DNA-directed RNA polymerase III subunit G-like)POLR3GLQ9BT433
DnaJ (Hsp40) homolog, subfamily C, member 9 (HCG2024613, isoform CRA_a) (cDNA FLJ36843 fis, clone ASTRO2012552, highly similar to DnaJ homolog subfamily C member 9)DNAJC9 hCG_2024613B2RMW63
DnaJ homolog subfamily B member 14DNAJB14 UNQ9427/PRO34683Q8TBM83
DnaJ homolog subfamily B member 9 (Endoplasmic reticulum DNA J domain-containing protein 4) (ER-resident protein ERdj4) (ERdj4) (Microvascular endothelial differentiation gene 1 protein) (Mdg-1)DNAJB9 MDG1 UNQ743/PRO1471Q9UBS33
DnaJ homolog subfamily C member 17DNAJC17Q9NVM63
DNAJB1 protein (DnaJ (Hsp40) homolog, subfamily B, member 1, isoform CRA_a) (cDNA, FLJ93008, Homo sapiens DnaJ (Hsp40) homolog, subfamily B, member 1 (DNAJB1),mRNA) (Fragment)DNAJB1 hCG_1776318Q6FHS43
Docking protein 6 (Downstream of tyrosine kinase 6)DOK6 DOK5LQ6PKX43
Dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase (EC 2.4.1.258) (Asparagine-linked glycosylation protein 3 homolog) (Dol-P-Man-dependent alpha(1-3)-mannosyltransferase) (Dolichyl-P-Man:Man(5)GlcNAc(2)-PP-dolichyl mannosyltransferase) (Dolichyl-phosphate-mannose--glycolipid alpha-mannosyltransferase) (Not56-like protein)ALG3 NOT NOT56LQ926853
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 4OST4P0C6T23
Double-strand break repair protein MRE11A (Meiotic recombination 11 homolog 1) (MRE11 homolog 1) (Meiotic recombination 11 homolog A) (MRE11 homolog A)MRE11A HNGS1 MRE11P499593
Doublecortin domain-containing protein 2 (Protein RU2S)DCDC2 KIAA1154 RU2Q9UHG03
DTYMK protein (Deoxythymidylate kinase (Thymidylate kinase)) (Deoxythymidylate kinase (Thymidylate kinase), isoform CRA_b) (Putative uncharacterized protein tmp_locus_5) (Fragment)DTYMK tmp_locus_5 hCG_93868Q6FGU23
Dual oxidase maturation factor 1 gamma (Homolog of Drosophila Numb-interacting protein, isoform CRA_b) (cDNA FLJ76085, highly similar to Homo sapiens homolog of Drosophila Numb-interacting protein (NIP), mRNA)NIP DUOXA1 hCG_2036886A8K9Q63
Dual specificity phosphatase DUPD1 (EC 3.1.3.16) (EC 3.1.3.48) (Dual specificity phosphatase 27)DUPD1 DUSP27Q68J443
Dual specificity protein phosphatase 14 (EC 3.1.3.16) (EC 3.1.3.48) (MKP-1-like protein tyrosine phosphatase) (MKP-L) (Mitogen-activated protein kinase phosphatase 6) (MAP kinase phosphatase 6) (MKP-6)DUSP14 MKP6O951473
Dual specificity tyrosine-phosphorylation-regulated kinase 4 (EC 2.7.12.1)DYRK4Q9NR203
Dynactin-associated protein (Full)DYNAP C18orf26Q8N1N23
Dynamin-1 (EC 3.6.5.5)DNM1 DNMQ051933
Dynein assembly factor 3, axonemalDNAAF3 C19orf51Q8N9W53
Dynein heavy chain 1, axonemal (Axonemal beta dynein heavy chain 1) (Ciliary dynein heavy chain 1) (Heat shock regulated protein 1) (HSRF-1) (hDHC7)DNAH1 DHC7 DNAHC1 KIAA1410Q9P2D73
Dysferlin (Dystrophy-associated fer-1-like protein) (Fer-1-like protein 1)DYSF FER1L1O759233
Dystrobrevin beta (DTN-B) (Beta-dystrobrevin)DTNBO609413
DystrophinDMDP115323
E2F-associated phosphoprotein (EAPP)EAPP C14orf11 BM-036Q56P033
E3 SUMO-protein ligase PIAS3 (EC 6.3.2.-) (Protein inhibitor of activated STAT protein 3)PIAS3Q9Y6X23
E3 ubiquitin-protein ligase BRE1A (BRE1-A) (hBRE1) (EC 6.3.2.-) (RING finger protein 20)RNF20 BRE1AQ5VTR23
E3 ubiquitin-protein ligase CHIP (EC 6.3.2.-) (Antigen NY-CO-7) (CLL-associated antigen KW-8) (Carboxy terminus of Hsp70-interacting protein) (STIP1 homology and U box-containing protein 1)STUB1 CHIP PP1131Q9UNE73
E3 ubiquitin-protein ligase MYLIP (EC 6.3.2.-) (Inducible degrader of the LDL-receptor) (Idol) (Myosin regulatory light chain interacting protein) (MIR)MYLIP BZF1 IDOL BM-023 PP5242Q8WY643
E3 ubiquitin-protein ligase NRDP1 (EC 6.3.2.-) (RING finger protein 41)RNF41 FLRF NRDP1 SBBI03Q9H4P43
E3 ubiquitin-protein ligase parkin (EC 6.3.2.-) (Parkinson juvenile disease protein 2) (Parkinson disease protein 2)PARK2 PRKNO602603
E3 ubiquitin-protein ligase RFWD3 (EC 6.3.2.-) (RING finger and WD repeat domain-containing protein 3) (RING finger protein 201)RFWD3 RNF201Q6PCD53
E3 ubiquitin-protein ligase RING2 (EC 6.3.2.-) (Huntingtin-interacting protein 2-interacting protein 3) (HIP2-interacting protein 3) (Protein DinG) (RING finger protein 1B) (RING1b) (RING finger protein 2) (RING finger protein BAP-1)RNF2 BAP1 DING HIPI3 RING1BQ994963
E3 ubiquitin-protein ligase RNF115 (EC 6.3.2.-) (RING finger protein 115) (Rabring 7) (Zinc finger protein 364)RNF115 ZNF364Q9Y4L53
E3 ubiquitin-protein ligase RNF149 (EC 6.3.2.-) (DNA polymerase-transactivated protein 2) (RING finger protein 149)RNF149 DNAPTP2Q8NC423
E3 ubiquitin-protein ligase SH3RF1 (EC 6.3.2.-) (Plenty of SH3s) (Protein POSH) (RING finger protein 142) (SH3 domain-containing RING finger protein 1) (SH3 multiple domains protein 2)SH3RF1 KIAA1494 POSH RNF142 SH3MD2Q7Z6J03
E3 ubiquitin-protein ligase synoviolin (EC 6.3.2.-) (Synovial apoptosis inhibitor 1)SYVN1 HRD1 KIAA1810Q86TM63
E3 ubiquitin-protein ligase TRIM13 (EC 6.3.2.-) (B-cell chronic lymphocytic leukemia tumor suppressor Leu5) (Leukemia-associated protein 5) (Putative tumor suppressor RFP2) (RING finger protein 77) (Ret finger protein 2) (Tripartite motif-containing protein 13)TRIM13 LEU5 RFP2 RNF77O608583
E3 ubiquitin-protein ligase TRIM17 (EC 6.3.2.-) (RING finger protein 16) (Testis RING finger protein) (Tripartite motif-containing protein 17)TRIM17 RBCC RNF16 TERFQ9Y5773
E3 ubiquitin-protein ligase TRIM39 (EC 6.3.2.-) (RING finger protein 23) (Testis-abundant finger protein) (Tripartite motif-containing protein 39)TRIM39 RNF23 TFPQ9HCM93
Early endosome antigen 1 (Endosome-associated protein p162) (Zinc finger FYVE domain-containing protein 2)EEA1 ZFYVE2Q150753
EBPL proteinEBPLQ6GPH73
Echinoderm microtubule-associated protein-like 3 (EMAP-3)EML3Q32P443
Echinoderm microtubule-associated protein-like 4 (EMAP-4) (Restrictedly overexpressed proliferation-associated protein) (Ropp 120)EML4 C2orf2 EMAPL4Q9HC353
Ectonucleoside triphosphate diphosphohydrolase 6 (NTPDase 6) (EC 3.6.1.6) (CD39 antigen-like 2)ENTPD6 CD39L2 IL6ST2O753543
EF-hand calcium-binding domain-containing protein 4B (Calcium release-activated calcium channel regulator 2A) (CRAC channel regulator 2A)EFCAB4B CRACR2AQ9BSW23
EH-domain containing 1, isoform CRA_b (cDNA FLJ40523 fis, clone TESTI2046872, highly similar to EH-domain-containing protein 1) (cDNA, FLJ92624, highly similar to Homo sapiens EH-domain containing 1 (EHD1), mRNA)EHD1 hCG_23386B2R5U33
EIF2S2 protein (Eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa) (Eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa, isoform CRA_b) (cDNA, FLJ93495, highly similar to Homo sapiens eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa (EIF2S2), mRNA)EIF2S2 hCG_2018881Q6IBR83
ELAV-like protein 1 (Hu-antigen R) (HuR)ELAVL1 HURQ157173
Ellis-van Creveld syndrome protein (DWF-1)EVCP576793
Elongation factor G, mitochondrial (EF-Gmt) (Elongation factor G 1, mitochondrial) (mEF-G 1) (Elongation factor G1) (hEFG1)GFM1 EFG EFG1 GFMQ96RP93
Elongator complex protein 4 (hELP4) (PAX6 neighbor gene protein)ELP4 C11orf19 PAXNEBQ96EB13
EMILIN-3 (EMILIN-5) (Elastin microfibril interface-located protein 3) (Elastin microfibril interfacer 3) (Elastin microfibril interface-located protein 5) (Elastin microfibril interfacer 5)EMILIN3 C20orf130 EMILIN5Q9NT223
Endonuclease G, mitochondrial (Endo G) (EC 3.1.30.-)ENDOGQ142493
Endonuclease/exonuclease/phosphatase family domain-containing protein 1EEPD1 KIAA1706Q7L9B93
Endophilin-B2 (SH3 domain-containing GRB2-like protein B2)SH3GLB2 KIAA1848 PP578Q9NR463
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