EVpedia provide top 100+ EV markers, selected according to their identification number.
Based on EV proteomes, we defined the identification number of protein A as the number of datasets which contain protein A.
Therefore, proteins with higher identification numbers were more conserved.

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Protein name Gene symbol UniProt accession Identification number
Galactose-3-O-sulfotransferase 2 (Gal3ST-2) (EC 2.8.2.-) (Beta-galactose-3-O-sulfotransferase 2) (Gal-beta-1, 3-GalNAc 3'-sulfotransferase 2) (Glycoprotein beta-Gal 3'-sulfotransferase 2)GAL3ST2 GP3STQ9H3Q33
Galactosyl transferase-associated proteinGTAPQ29SN73
Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1 (EC 2.4.1.135) (Beta-1,3-glucuronyltransferase 1) (Glucuronosyltransferase P) (GlcAT-P) (UDP-GlcUA:glycoprotein beta-1,3-glucuronyltransferase) (GlcUAT-P)B3GAT1 GLCATPQ9P2W73
Galectin-3-binding protein (Basement membrane autoantigen p105) (Lectin galactoside-binding soluble 3-binding protein) (Mac-2-binding protein) (MAC2BP) (Mac-2 BP) (Tumor-associated antigen 90K)LGALS3BP M2BPQ083803
Galectin-9 (Gal-9) (Ecalectin) (Tumor antigen HOM-HD-21)LGALS9O001823
Galectin-9C (Gal-9C) (Galectin-9-like protein B)LGALS9CQ6DKI23
Gametogenetin-binding protein 2 (Laryngeal carcinoma-related protein 1) (Protein ZNF403)GGNBP2 LCRG1 LZK1 ZNF403Q9H3C73
Gamma-aminobutyric acid receptor subunit gamma-2 (GABA(A) receptor subunit gamma-2)GABRG2P185073
Gamma-butyrobetaine dioxygenase (EC 1.14.11.1) (Gamma-butyrobetaine hydroxylase) (Gamma-BBH) (Gamma-butyrobetaine,2-oxoglutarate dioxygenase)BBOX1 BBH BBOXO759363
Gamma-crystallin A (Gamma-A-crystallin) (Gamma-crystallin 5)CRYGA CRYG1P118443
Gamma-glutamyltransferase light chain 2 (Gamma-glutamyltransferase-like protein 4)GGTLC2 GGTL4Q143903
Gamma-synuclein (Breast cancer-specific gene 1 protein) (Persyn) (Synoretin) (SR)SNCG BCSG1 PERSYN PRSNO760703
Gamma-tubulin complex component 2 (GCP-2) (hGCP2) (Gamma-ring complex protein 103 kDa) (h103p) (hGrip103) (Spindle pole body protein Spc97 homolog) (hSpc97)TUBGCP2 GCP2Q9BSJ23
Gamma-tubulin complex component 5 (GCP-5)TUBGCP5 GCP5 KIAA1899Q96RT83
Gamma-tubulin complex component 6 (GCP-6)TUBGCP6 GCP6 KIAA1669Q96RT73
Ganglioside GM2 activator (Cerebroside sulfate activator protein) (GM2-AP) (Sphingolipid activator protein 3) (SAP-3) [Cleaved into: Ganglioside GM2 activator isoform short]GM2AP179003
Ganglioside-induced differentiation-associated protein 1-like 1 (GDAP1-L1)GDAP1L1Q96MZ03
Ganglioside-induced differentiation-associated protein 2GDAP2Q9NXN43
Gap junction alpha-4 protein (Connexin-37) (Cx37)GJA4P352123
Gap junction delta-2 protein (Connexin-36) (Cx36) (Gap junction alpha-9 protein)GJD2 GJA9Q9UKL43
Gap junction proteinGJB2 hCG_18943H9U1J43
GC-rich sequence DNA-binding factor 2 (GC-rich sequence DNA-binding factor) (Transcription factor 9) (TCF-9)GCFC2 C2orf3 GCF TCF9P163833
GDF10 protein0Q8N6T23
Gem-associated protein 4 (Gemin-4) (Component of gems 4) (p97)GEMIN4P576783
General transcription factor 3C polypeptide 1 (TF3C-alpha) (TFIIIC box B-binding subunit) (Transcription factor IIIC 220 kDa subunit) (TFIIIC 220 kDa subunit) (TFIIIC220) (Transcription factor IIIC subunit alpha)GTF3C1Q127893
General transcription factor 3C polypeptide 6 (Transcription factor IIIC 35 kDa subunit) (TFIIIC 35 kDa subunit) (TFIIIC35) (Transcription factor IIIC subunit 6)GTF3C6 C6orf51 CDA020 NPD020Q969F13
General transcription factor II-I (GTFII-I) (TFII-I) (Bruton tyrosine kinase-associated protein 135) (BAP-135) (BTK-associated protein 135) (SRF-Phox1-interacting protein) (SPIN) (Williams-Beuren syndrome chromosomal region 6 protein)GTF2I BAP135 WBSCR6P783473
Geranylgeranyl transferase type-1 subunit beta (EC 2.5.1.59) (Geranylgeranyl transferase type I subunit beta) (GGTase-I-beta) (Type I protein geranyl-geranyltransferase subunit beta)PGGT1BP536093
GIG10 (Migration-inducing gene 18 protein) (cDNA, FLJ93821, Homo sapiens SH3-domain kinase binding protein 1 (SH3KBP1), mRNA)0Q5JPT63
Glia maturation factor gamma (GMF-gamma)GMFGO602343
Glial cell line-derived neurotrophic factor (hGDNF) (Astrocyte-derived trophic factor) (ATF)GDNFP399053
Glial fibrillary acidic protein (GFAP)GFAPP141363
GLIPR1-like protein 2GLIPR1L2Q4G1C93
GLTSCR1-like protein (Glioma tumor suppressor candidate region gene 1 protein-like)GLTSCR1L KIAA0240Q6AI393
Glucokinase regulatory protein (Glucokinase regulator)GCKRQ143973
Glucose-6-phosphate translocase (Glucose-5-phosphate transporter) (Solute carrier family 37 member 4) (Transformation-related gene 19 protein) (TRG-19)SLC37A4 G6PT G6PT1 PRO0685 TRG19O438263
Glucose-dependent insulinotropic receptor (G-protein coupled receptor 119)GPR119Q8TDV53
Glutamate carboxypeptidase 2 (EC 3.4.17.21) (Cell growth-inhibiting gene 27 protein) (Folate hydrolase 1) (Folylpoly-gamma-glutamate carboxypeptidase) (FGCP) (Glutamate carboxypeptidase II) (GCPII) (Membrane glutamate carboxypeptidase) (mGCP) (N-acetylated-alpha-linked acidic dipeptidase I) (NAALADase I) (Prostate-specific membrane antigen) (PSM) (PSMA) (Pteroylpoly-gamma-glutamate carboxypeptidase)FOLH1 FOLH NAALAD1 PSM PSMA GIG27Q046093
Glutamate receptor ionotropic, kainate 1 (GluK1) (Excitatory amino acid receptor 3) (EAA3) (Glutamate receptor 5) (GluR-5) (GluR5)GRIK1 GLUR5P390863
Glutamate receptor ionotropic, NMDA 2C (GluN2C) (Glutamate [NMDA] receptor subunit epsilon-3) (N-methyl D-aspartate receptor subtype 2C) (NMDAR2C) (NR2C)GRIN2C NMDAR2CQ149573
Glutamine--tRNA ligase (EC 6.1.1.18) (Glutaminyl-tRNA synthetase) (GlnRS)QARSP478973
Glutaminyl-peptide cyclotransferase (EC 2.3.2.5) (Glutaminyl cyclase) (QC) (sQC) (Glutaminyl-tRNA cyclotransferase) (Glutamyl cyclase) (EC)QPCTQ167693
Glutamyl-tRNA(Gln) amidotransferase subunit A, mitochondrial (Glu-AdT subunit A) (EC 6.3.5.-) (Glutaminyl-tRNA synthase-like protein 1)QRSL1Q9H0R63
Glutathione peroxidaseGPX1Q7L4Q33
Glutathione peroxidase 2 (GPx-2) (GSHPx-2) (EC 1.11.1.9) (Gastrointestinal glutathione peroxidase) (Glutathione peroxidase-gastrointestinal) (GPx-GI) (GSHPx-GI) (Glutathione peroxidase-related protein 2) (GPRP-2)GPX2P182833
Glutathione S-transferase M5, isoform CRA_b (cDNA, FLJ96269, Homo sapiens glutathione S-transferase M5 (GSTM5), mRNA)GSTM5 hCG_40245Q5T8R23
Glutathione S-transferase theta-1 (EC 2.5.1.18) (GST class-theta-1) (Glutathione transferase T1-1)GSTT1P307113
Glutathione S-transferase theta-2B (EC 2.5.1.18) (GST class-theta-2) (Glutathione S-transferase theta-2)GSTT2B GSTT2P0CG303
Glycerophosphodiester phosphodiesterase domain-containing protein 3 (EC 3.1.-.-)GDPD3Q7L5L33
Glycine N-acyltransferase (EC 2.3.1.13) (EC 2.3.1.71) (Acyl-CoA:glycine N-acyltransferase) (AAc) (Aralkyl acyl-CoA N-acyltransferase) (Aralkyl acyl-CoA:amino acid N-acyltransferase) (Benzoyl-coenzyme A:glycine N-acyltransferase) (Glycine N-benzoyltransferase) (HRP-1(CLP))GLYAT ACGNAT CAT GATQ6IB773
Glycogen phosphorylase, brain form (EC 2.4.1.1)PYGBP112163
Glycolipid transfer protein (GLTP)GLTPQ9NZD23
Glycoprotein endo-alpha-1,2-mannosidase (Endo-alpha mannosidase) (Endomannosidase) (hEndo) (EC 3.2.1.130) (Mandaselin)MANEAQ5SRI93
Glycoprotein endo-alpha-1,2-mannosidase-like protein (EC 3.2.1.-)MANEALQ5VSG83
Glycylpeptide N-tetradecanoyltransferase 2 (EC 2.3.1.97) (Myristoyl-CoA:protein N-myristoyltransferase 2) (NMT 2) (Peptide N-myristoyltransferase 2) (Type II N-myristoyltransferase)NMT2O605513
GOLGA6 protein (Fragment)GOLGA6A2VDJ13
Golgi pH regulator A (Protein GPR89A) (Putative MAPK-activating protein PM01) (Putative NF-kappa-B-activating protein 90)GPR89A GPHRA GPR89 SH120 CGI-13 UNQ192/PRO218B7ZAQ63
Golgi SNAP receptor complex member 1 (28 kDa Golgi SNARE protein) (28 kDa cis-Golgi SNARE p28) (GOS-28)GOSR1 GS28O952493
Golgin subfamily A member 7BGOLGA7B C10orf132 C10orf133Q2TAP03
Grainyhead-like protein 2 homolog (Brother of mammalian grainyhead) (Transcription factor CP2-like 3)GRHL2 BOM TFCP2L3Q6ISB33
GRAM domain-containing protein 3 (HCV NS3-transactivated protein 2)GRAMD3 NS3TP2Q96HH93
Granulocyte-macrophage colony-stimulating factor (GM-CSF) (Colony-stimulating factor) (CSF) (Molgramostin) (Sargramostim)CSF2 GMCSFP041413
Gremlin-2 (Cysteine knot superfamily 1, BMP antagonist 2) (DAN domain family member 3) (Protein related to DAN and cerberus)GREM2 CKTSF1B2 DAND3 PRDCQ9H7723
GRIA2 protein (Fragment)GRIA2I6L9973
GRIP and coiled-coil domain-containing protein 2 (185 kDa Golgi coiled-coil protein) (GCC185) (CLL-associated antigen KW-11) (CTCL tumor antigen se1-1) (Ran-binding protein 2-like 4) (RanBP2L4) (Renal carcinoma antigen NY-REN-53)GCC2 KIAA0336 RANBP2L4Q8IWJ23
Growth arrest and DNA damage-inducible proteins-interacting protein 1 (39S ribosomal protein L59, mitochondrial) (MRP-L59) (CKII beta-associating protein) (CR6-interacting factor 1) (CRIF1) (Papillomavirus L2-interacting nuclear protein 1) (PLINP) (PLINP-1) (p53-responsive gene 6 protein)GADD45GIP1 MRPL59 PLINP1 PRG6Q8TAE83
Growth factor receptor-bound protein 10 (GRB10 adapter protein) (Insulin receptor-binding protein Grb-IR)GRB10 GRBIR KIAA0207Q133223
Growth factor receptor-bound protein 14 (GRB14 adapter protein)GRB14Q144493
Growth hormone receptor (GH receptor) (Somatotropin receptor) [Cleaved into: Growth hormone-binding protein (GH-binding protein) (GHBP) (Serum-binding protein)]GHRP109123
Growth/differentiation factor 5 (GDF-5) (Cartilage-derived morphogenetic protein 1) (CDMP-1) (Radotermin)GDF5 CDMP1P430263
GS homeobox 1 (Homeobox protein GSH-1)GSX1 GSH1Q9H4S23
GTP-binding protein Di-Ras1 (Distinct subgroup of the Ras family member 1) (Ras-related inhibitor of cell growth) (Rig) (Small GTP-binding tumor suppressor 1)DIRAS1 GBTS1 RIGO950573
GTP-binding protein GEM (GTP-binding mitogen-induced T-cell protein) (RAS-like protein KIR)GEM KIRP550403
GTPase-activating protein for Cdc42 and Rac1RICSI7H0B03
Guanine nucleotide exchange factor for Rab-3A (Rab-3A-interacting-like protein 1) (Rab3A-interacting-like protein 1) (Rabin3-like 1)RAB3IL1Q8TBN03
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11GNG11 GNGT11P619523
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4GNG4 GNGT4P501503
Guanine nucleotide-binding protein G(T) subunit gamma-T1 (Transducin gamma chain)GNGT1P632113
Guanine nucleotide-binding protein subunit beta-5 (Gbeta5) (Transducin beta chain 5)GNB5O147753
Guanylate-binding protein 3 (GTP-binding protein 3) (GBP-3) (Guanine nucleotide-binding protein 3)GBP3Q9H0R53
Guanylate-binding protein 4 (GTP-binding protein 4) (GBP-4) (Guanine nucleotide-binding protein 4)GBP4Q96PP93
Guanylin (Guanylate cyclase activator 2A) (Guanylate cyclase-activating protein 1) (Guanylate cyclase-activating protein I) (GCAP-I) [Cleaved into: HMW-guanylin; Guanylin]GUCA2A GUCA2Q027473
H(+)/Cl(-) exchange transporter 3 (Chloride channel protein 3) (ClC-3) (Chloride transporter ClC-3)CLCN3P517903
Haloacid dehalogenase-like hydrolase domain-containing protein 3HDHD3 C9orf158Q9BSH53
HAUS augmin-like complex subunit 6HAUS6 DGT6 FAM29A KIAA1574Q7Z4H73
HDAC4 protein (Histone deacetylase 4, isoform CRA_a)HDAC4 hCG_22188Q86YH73
HEAT repeat-containing protein 3HEATR3Q7Z4Q23
Heat shock factor protein 1 (HSF 1) (Heat shock transcription factor 1) (HSTF 1)HSF1 HSTF1Q006133
Heme-binding protein 1 (p22HBP)HEBP1 HBPQ9NRV93
Hemicentin-1 (Fibulin-6) (FIBL-6)HMCN1 FIBL6Q96RW73
Hemoglobin subunit epsilon (Epsilon-globin) (Hemoglobin epsilon chain)HBE1 HBEP021003
Hemoglobin subunit mu (Hemoglobin mu chain) (Mu-globin)HBM HBAP2Q6B0K93
Heparan sulfate glucosamine 3-O-sulfotransferase 3A1 (EC 2.8.2.30) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 3A1) (3-OST-3A) (Heparan sulfate 3-O-sulfotransferase 3A1) (h3-OST-3A)HS3ST3A1 3OST3A1 HS3ST3A UNQ2551/PRO6180Q9Y6633
Hepatocyte nuclear factor 3-gamma (HNF-3-gamma) (HNF-3G) (Fork head-related protein FKH H3) (Forkhead box protein A3) (Transcription factor 3G) (TCF-3G)FOXA3 HNF3G TCF3GP553183
Hepcidin (Liver-expressed antimicrobial peptide 1) (LEAP-1) (Putative liver tumor regressor) (PLTR) [Cleaved into: Hepcidin-25 (Hepc25); Hepcidin-20 (Hepc20)]HAMP HEPC LEAP1 UNQ487/PRO1003P811723
Hermansky-Pudlak syndrome 6 protein (Ruby-eye protein homolog) (Ru)HPS6Q86YV93
Heterogeneous nuclear ribonucleoprotein C-like 1 (hnRNP C-like-1) (hnRNP core protein C-like 1)HNRNPCL1 HNRPCL1O608123
Heterogeneous nuclear ribonucleoprotein U-like protein 2 (Scaffold-attachment factor A2) (SAF-A2)HNRNPUL2 HNRPUL2Q1KMD33
High affinity immunoglobulin alpha and immunoglobulin mu Fc receptor (Fc alpha/mu receptor) (CD antigen CD351)FCAMR FKSG87Q8WWV63
High affinity nerve growth factor receptor (EC 2.7.10.1) (Neurotrophic tyrosine kinase receptor type 1) (TRK1-transforming tyrosine kinase protein) (Tropomyosin-related kinase A) (Tyrosine kinase receptor) (Tyrosine kinase receptor A) (Trk-A) (gp140trk) (p140-TrkA)NTRK1 MTC TRK TRKAP046293
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