EVpedia provide top 100+ EV markers, selected according to their identification number.
Based on EV proteomes, we defined the identification number of protein A as the number of datasets which contain protein A.
Therefore, proteins with higher identification numbers were more conserved.

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Protein name Gene symbol UniProt accession Identification number
Inward rectifier potassium channel 16 (Inward rectifier K(+) channel Kir5.1) (Potassium channel, inwardly rectifying subfamily J member 16)KCNJ16Q9NPI93
IQ domain-containing protein GIQCGQ9H0953
Iron-sulfur cluster co-chaperone protein HscB, mitochondrial (DnaJ homolog subfamily C member 20) (Hsc20)HSCB DNAJC20 HSC20Q8IWL33
Islet cell autoantigen 1-like protein (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 14 protein) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 15 protein)ICA1L ALS2CR14 ALS2CR15Q8NDH63
Isthmin-2 (Thrombospondin and AMOP domain-containing isthmin-like protein 1) (Thrombospondin type-1 domain-containing protein 3)ISM2 TAIL1 THSD3 PSEC0137Q6H9L73
Jun dimerization protein 2JDP2Q8WYK23
Junctophilin-1 (JP-1) (Junctophilin type 1)JPH1 JP1Q9HDC53
Juxtaposed with another zinc finger protein 1 (TAK1-interacting protein 27) (Zinc finger protein 802)JAZF1 TIP27 ZNF802Q86VZ63
Kallikrein 9 (Kallikrein 9, isoform CRA_b)KLK9 hCG_1733566Q2XQG63
Kallikrein-1 (EC 3.4.21.35) (Kidney/pancreas/salivary gland kallikrein) (Tissue kallikrein)KLK1P068703
Kallikrein-10 (EC 3.4.21.-) (Normal epithelial cell-specific 1) (Protease serine-like 1)KLK10 NES1 PRSSL1O432403
Kallikrein-13 (EC 3.4.21.-) (Kallikrein-like protein 4) (KLK-L4)KLK13 KLKL4Q9UKR33
Kallikrein-4 (EC 3.4.21.-) (Enamel matrix serine proteinase 1) (Kallikrein-like protein 1) (KLK-L1) (Prostase) (Serine protease 17)KLK4 EMSP1 PRSS17 PSTSQ9Y5K23
Kallikrein-6 (EC 3.4.21.-) (Neurosin) (Protease M) (SP59) (Serine protease 18) (Serine protease 9) (Zyme)KLK6 PRSS18 PRSS9Q928763
Kallikrein-7 (hK7) (EC 3.4.21.117) (Serine protease 6) (Stratum corneum chymotryptic enzyme) (hSCCE)KLK7 PRSS6 SCCEP498623
KCNK4 protein (Fragment)KCNK4Q2YDA13
KDEL motif-containing protein 2KDELC2 UNQ1904/PRO4350Q7Z4H83
Kelch domain-containing protein 3 (Protein Peas) (Testis intracellular mediator protein)KLHDC3 PEASQ9BQ903
Kelch domain-containing protein 9 (Kelch/ankyrin repeat-containing cyclin A1-interacting protein)KLHDC9 KARCA1Q8NEP73
Kelch-like protein 20 (Kelch-like ECT2-interacting protein) (Kelch-like protein X)KLHL20 KLEIPQ9Y2M53
Kelch-like protein 23KLHL23Q8NBE83
Kelch-like protein 7KLHL7Q8IXQ53
Keratin, type I cuticular Ha1 (Hair keratin, type I Ha1) (Keratin-31) (K31)KRT31 HHA1 HKA1 KRTHA1Q153233
Keratin, type I cuticular Ha3-I (Hair keratin, type I Ha3-I) (Keratin-33A) (K33A)KRT33A HHA3-I HKA3A KRTHA3AO760093
Keratin, type II cuticular Hb4 (Keratin-84) (K84) (Type II hair keratin Hb4) (Type-II keratin Kb24)KRT84 KRTHB4Q9NSB23
Keratin, type II cuticular Hb5 (Hair keratin K2.12) (Keratin-85) (K85) (Type II hair keratin Hb5) (Type-II keratin Kb25)KRT85 KRTHB5P783863
Keratin, type II cuticular Hb6 (Hair keratin K2.11) (Keratin-86) (K86) (Type II hair keratin Hb6) (Type-II keratin Kb26)KRT86 KRTHB6O437903
Keratin, type II cytoskeletal 7 (Cytokeratin-7) (CK-7) (Keratin-7) (K7) (Sarcolectin) (Type-II keratin Kb7)KRT7 SCLP087293
Keratin-associated protein 1-5 (High sulfur keratin-associated protein 1.5) (Keratin-associated protein 1.5)KRTAP1-5 KAP1.5 KRTAP1.5Q9BYS13
Keratin-associated protein 10-2 (High sulfur keratin-associated protein 10.2) (Keratin-associated protein 10.2) (Keratin-associated protein 18-2) (Keratin-associated protein 18.2)KRTAP10-2 KAP10.2 KAP18-2 KRTAP10.2 KRTAP18-2 KRTAP18.2P603683
Keratin-associated protein 10-3 (High sulfur keratin-associated protein 10.3) (Keratin-associated protein 10.3) (Keratin-associated protein 18-3) (Keratin-associated protein 18.3)KRTAP10-3 KAP10.3 KAP18-3 KRTAP10.3 KRTAP18-3 KRTAP18.3P603693
Keratin-associated protein 17-1 (Keratin-associated protein 16.1)KRTAP17-1 KAP17.1 KRTAP16.1Q9BYP83
Keratin-associated protein 23-1KRTAP23-1 KAP23.1A1A5803
Keratin-associated protein 3-2 (High sulfur keratin-associated protein 3.2) (Keratin-associated protein 3.2)KRTAP3-2 KAP3.2 KRTAP3.2Q9BYR73
Keratin-associated protein 4-1 (Keratin-associated protein 4-10) (Keratin-associated protein 4.1) (Keratin-associated protein 4.10) (Ultrahigh sulfur keratin-associated protein 4.10)KRTAP4-1 KAP4.10 KRTAP4-10 KRTAP4.1 KRTAP4.10Q9BYQ73
Keratin-associated protein 4-2 (Keratin-associated protein 4.2) (Ultrahigh sulfur keratin-associated protein 4.2)KRTAP4-2 KAP4.2 KRTAP4.2Q9BYR53
Keratin-associated protein 4-9 (Keratin-associated protein 4.9) (Ultrahigh sulfur keratin-associated protein 4.9)KRTAP4-9 KAP4.9 KRTAP4.9Q9BYQ83
Keratin-associated protein 5-3 (Keratin-associated protein 5-9) (Keratin-associated protein 5.3) (Keratin-associated protein 5.9) (UHS KerB-like) (Ultrahigh sulfur keratin-associated protein 5.3)KRTAP5-3 KAP5-9 KAP5.3 KRTAP5-9 KRTAP5.3 KRTAP5.9Q6L8H23
Keratin-associated protein 5-4 (Keratin-associated protein 5.4) (Ultrahigh sulfur keratin-associated protein 5.4)KRTAP5-4 KAP5.4 KRTAP5.4Q6L8H13
Keratin-associated protein 5-8 (Keratin, ultra high-sulfur matrix protein B) (Keratin-associated protein 5.8) (UHS keratin B) (UHS KerB) (Ultrahigh sulfur keratin-associated protein 5.8)KRTAP5-8 KAP5.8 KRTAP5.8 UHSKBO756903
Keratin-associated protein 9-4 (Keratin-associated protein 9.4) (Ultrahigh sulfur keratin-associated protein 9.4)KRTAP9-4 KAP9.4 KRTAP9.4Q9BYQ23
Keratin-associated protein 9-8 (Keratin-associated protein 9.8) (Ultrahigh sulfur keratin-associated protein 9.8)KRTAP9-8 KAP9.8 KRTAP9.8Q9BYQ03
Keratinocyte differentiation-associated proteinKRTDAP KDAP UNQ467/PRO826P609853
Ketimine reductase mu-crystallin (EC 1.5.1.25) (NADP-regulated thyroid-hormone-binding protein)CRYM THBPQ148943
Ketohexokinase (EC 2.7.1.3) (Hepatic fructokinase)KHKP500533
KIF1-binding proteinKIAA1279 KBPQ96EK53
KIF5B protein (Fragment)KIF5BQ6P1643
Killer cell immunoglobulin-like receptor 2DL3 (CD158 antigen-like family member B2) (KIR-023GB) (Killer inhibitory receptor cl 2-3) (MHC class I NK cell receptor) (NKAT2a) (NKAT2b) (Natural killer-associated transcript 2) (NKAT-2) (p58 natural killer cell receptor clone CL-6) (p58 NK receptor CL-6) (p58.2 MHC class-I-specific NK receptor) (CD antigen CD158b2)KIR2DL3 CD158B2 KIRCL23 NKAT2P436283
Killer cell immunoglobulin-like receptor 3DL3 (CD158 antigen-like family member Z) (Killer cell inhibitory receptor 1) (CD antigen CD158z)KIR3DL3 CD158Z KIR3DL7 KIRC1Q8N7433
Kin of IRRE-like protein 2 (Kin of irregular chiasm-like protein 2) (Nephrin-like protein 3)KIRREL2 NEPH3 UNQ5827/PRO19646Q6UWL63
Kinesin-like protein KIF15 (Kinesin-like protein 2) (hKLP2) (Kinesin-like protein 7) (Serologically defined breast cancer antigen NY-BR-62)KIF15 KLP2 KNSL7Q9NS873
Kinesin-like protein KIF21A (Kinesin-like protein KIF2) (Renal carcinoma antigen NY-REN-62)KIF21A KIAA1708 KIF2Q7Z4S63
Kinesin-like protein KIF2C (Kinesin-like protein 6) (Mitotic centromere-associated kinesin) (MCAK)KIF2C KNSL6Q996613
Kinetochore-associated protein 1 (Rough deal homolog) (HsROD) (Rod) (hRod)KNTC1 KIAA0166P507483
Kinetochore-associated protein DSN1 homologDSN1 C20orf172 MIS13Q9H4103
Kit ligand (Mast cell growth factor) (MGF) (Stem cell factor) (SCF) (c-Kit ligand) [Cleaved into: Soluble KIT ligand (sKITLG)]KITLG MGF SCFP215833
KRAB domain-containing protein ZNF747ZNF747Q9BV973
Kremen protein 1 (Dickkopf receptor) (Kringle domain-containing transmembrane protein 1) (Kringle-containing protein marking the eye and the nose)KREMEN1 KREMEN KRM1Q96MU83
Kringle-containing transmembrane protein 2 isoform b variant (Fragment)0Q53F673
Krueppel-like factor 1 (Erythroid krueppel-like transcription factor) (EKLF)KLF1 EKLFQ133513
Krueppel-like factor 11 (Transforming growth factor-beta-inducible early growth response protein 2) (TGFB-inducible early growth response protein 2) (TIEG-2)KLF11 FKLF TIEG2O149013
Krueppel-like factor 15 (Kidney-enriched krueppel-like factor)KLF15 KKLFQ9UIH93
Kruppel-like factor 14KLF14 hCG_1807178A4D1N03
Kynurenine--oxoglutarate transaminase 3 (EC 2.6.1.7) (Cysteine-S-conjugate beta-lyase 2) (EC 4.4.1.13) (Kynurenine aminotransferase III) (KATIII) (Kynurenine--glyoxylate transaminase) (EC 2.6.1.63) (Kynurenine--oxoglutarate transaminase III)CCBL2 KAT3Q6YP213
Lactoperoxidase (LPO) (EC 1.11.1.7) (Salivary peroxidase) (SPO)LPO SAPXP220793
Late cornified envelope protein 1E (Late envelope protein 5)LCE1E LEP5Q5T7533
Late cornified envelope protein 2B (Late envelope protein 10) (Skin-specific protein Xp5) (Small proline-rich-like epidermal differentiation complex protein 1B)LCE2B LEP10 SPRL1B XP5O146333
Late cornified envelope protein 3B (Late envelope protein 14)LCE3B LEP14Q5TA773
LEM domain-containing protein 2 (hLEM2)LEMD2Q8NC563
Leucine zipper putative tumor suppressor 1 (F37/esophageal cancer-related gene-coding leucine-zipper motif) (Fez1)LZTS1 FEZ1Q9Y2503
Leucine--tRNA ligase, cytoplasmic (EC 6.1.1.4) (Leucyl-tRNA synthetase) (LeuRS)LARS KIAA1352Q9P2J53
Leucine-rich repeat LGI family member 3 (LGI1-like protein 4) (Leucine-rich glioma-inactivated protein 3)LGI3 LGIL4 UNQ8190/PRO23199Q8N1453
Leucine-rich repeat transmembrane protein FLRT3 (Fibronectin-like domain-containing leucine-rich transmembrane protein 3)FLRT3 KIAA1469 UNQ856/PRO1865Q9NZU03
Leucine-rich repeat-containing G protein-coupled receptor 4 variant (Fragment)0Q59ER83
Leucine-rich repeat-containing protein 1 (LANO adapter protein) (LAP and no PDZ protein)LRRC1 LANOQ9BTT63
Leucine-rich repeat-containing protein 41 (Protein Muf1)LRRC41 MUF1 PP7759Q153453
Leucine-rich repeat-containing protein 4B (Netrin-G3 ligand) (NGL-3)LRRC4B LRIG4Q9NT993
Leucine-rich repeat-containing protein 56LRRC56Q8IYG63
Leucine-rich repeat-containing protein 8ELRRC8EQ6NSJ53
Leukocyte immunoglobulin-like receptor subfamily A member 1 (CD85 antigen-like family member I) (Leukocyte immunoglobulin-like receptor 6) (LIR-6) (CD antigen CD85i)LILRA1 LIR6O750193
Leukocyte receptor cluster member 9LENG9Q96B703
LeupaxinLPXN LDLPO607113
LHX1 protein (Fragment)LHX1Q58F183
LIM and senescent cell antigen-like-containing domain protein 2 (LIM-like protein 2) (Particularly interesting new Cys-His protein 2) (PINCH-2)LIMS2 PINCH2Q7Z4I73
LIM domain kinase 1 (LIMK-1) (EC 2.7.11.1)LIMK1 LIMKP536673
LIM domain kinase 2 (LIMK-2) (EC 2.7.11.1)LIMK2P536713
LIM domain only protein 3 (LMO-3) (Neuronal-specific transcription factor DAT1) (Rhombotin-3)LMO3 RBTN3 RBTNL2 RHOM3Q8TAP43
Linker for activation of T-cells family member 2 (Linker for activation of B-cells) (Membrane-associated adapter molecule) (Non-T-cell activation linker) (Williams-Beuren syndrome chromosomal region 15 protein) (Williams-Beuren syndrome chromosomal region 5 protein)LAT2 LAB NTAL WBS15 WBSCR15 WBSCR5 HSPC046Q9GZY63
Lipase maturation factor 1 (Putative uncharacterized protein LA16c-360B4.1) (cDNA FLJ35731 fis, clone TESTI2003139)LMF1 LA16c-360B4.1 hCG_22432B3KS803
Lipid phosphate phosphohydrolase 1 (EC 3.1.3.4) (PAP2-alpha) (Phosphatidate phosphohydrolase type 2a) (Phosphatidic acid phosphatase 2a) (PAP-2a) (PAP2a)PPAP2A LPP1O144943
Lipolysis-stimulated lipoprotein receptorLSR LISCHQ86X293
Lipoma HMGIC fusion partnerLHFPQ9Y6933
Liprin-beta-2 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 2) (PTPRF-interacting protein-binding protein 2)PPFIBP2Q8ND303
LMBR1 domain-containing protein 2LMBRD2Q68DH53
Long-chain-fatty-acid--CoA ligase 1 (EC 6.2.1.3) (Acyl-CoA synthetase 1) (ACS1) (Long-chain acyl-CoA synthetase 1) (LACS 1) (Long-chain acyl-CoA synthetase 2) (LACS 2) (Long-chain fatty acid-CoA ligase 2) (Palmitoyl-CoA ligase 1) (Palmitoyl-CoA ligase 2)ACSL1 FACL1 FACL2 LACS LACS1 LACS2P331213
Long-chain-fatty-acid--CoA ligase 5 (EC 6.2.1.3) (Long-chain acyl-CoA synthetase 5) (LACS 5)ACSL5 ACS5 FACL5 UNQ633/PRO1250Q9ULC53
Low-density lipoprotein receptor class A domain-containing protein 3LDLRAD3Q86YD53
LY6/PLAUR domain containing 3 (cDNA PSEC0157 fis, clone PLACE1008238, highly similar to Ly6/PLAUR domain-containing protein 3) (cDNA, FLJ95643, Homo sapiens GPI-anchored metastasis-associated protein homolog(C4.4A), mRNA)LYPD3 hCG_20277B2RBR33
Ly6/PLAUR domain-containing protein 5LYPD5 UNQ1908/PRO4356Q6UWN53
Lymphokine-activated killer T-cell-originated protein kinase (EC 2.7.12.2) (Cancer/testis antigen 84) (CT84) (MAPKK-like protein kinase) (Nori-3) (PDZ-binding kinase) (Spermatogenesis-related protein kinase) (SPK) (T-LAK cell-originated protein kinase)PBK TOPKQ96KB53
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