EVpedia provide top 100+ EV markers, selected according to their identification number.
Based on EV proteomes, we defined the identification number of protein A as the number of datasets which contain protein A.
Therefore, proteins with higher identification numbers were more conserved.

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Protein name Gene symbol UniProt accession Identification number
mRNA cap guanine-N7 methyltransferase (EC 2.1.1.56) (RG7MT1) (mRNA (guanine-N(7)-)-methyltransferase) (mRNA cap methyltransferase) (hCMT1) (hMet) (hcm1p)RNMT KIAA0398O431483
mTERF domain-containing protein 1, mitochondrial (Mitochondrial transcription termination factor 3) (mTERF3)MTERFD1 CGI-12Q96E293
Mu-type opioid receptor (M-OR-1) (MOR-1) (Mu opiate receptor) (Mu opioid receptor) (MOP) (hMOP)OPRM1 MOR1P353723
Mucin-4 (MUC-4) (Ascites sialoglycoprotein) (ASGP) (Pancreatic adenocarcinoma mucin) (Testis mucin) (Tracheobronchial mucin) [Cleaved into: Mucin-4 alpha chain (Ascites sialoglycoprotein 1) (ASGP-1); Mucin-4 beta chain (Ascites sialoglycoprotein 2) (ASGP-2)]MUC4Q991023
Mucin-like protein 1 (Protein BS106) (Small breast epithelial mucin)MUCL1 SBEM UNQ590/PRO1160Q96DR83
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (EC 3.4.22.-) (MALT lymphoma-associated translocation) (Paracaspase)MALT1 MLTQ9UDY83
Multidrug and toxin extrusion protein 1 (MATE-1) (hMATE-1) (Solute carrier family 47 member 1)SLC47A1 MATE1Q96FL83
Multiple myeloma tumor-associated protein 2 (hMMTAG2)MMTAG2 C1orf35Q9BU763
Muscarinic acetylcholine receptor M4CHRM4P081733
Myb/SANT-like DNA-binding domain-containing protein 4 (Myb/SANT-like DNA-binding domain containing 4 with coiled-coils)MSANTD4 KIAA1826 DC25Q8NCY63
Myelin protein zero-like protein 1 (Protein zero-related)MPZL1 PZR UNQ849/PRO1787O952973
Myeloblastin (EC 3.4.21.76) (AGP7) (C-ANCA antigen) (Leukocyte proteinase 3) (PR-3) (PR3) (Neutrophil proteinase 4) (NP-4) (P29) (Wegener autoantigen)PRTN3 MBNP241583
Myeloid leukemia factor 1 (Myelodysplasia-myeloid leukemia factor 1)MLF1P583403
Myeloid-associated differentiation marker-like protein 2MYADML2A6NDP73
MYH10 protein (Fragment)MYH10Q9BWG03
Myocyte-specific enhancer factor 2B (RSRFR2) (Serum response factor-like protein 2)MEF2B XMEF2Q020803
MyoD family inhibitor domain-containing protein (I-mfa domain-containing protein) (hIC)MDFICQ9P1T73
Myomesin-2 (165 kDa connectin-associated protein) (165 kDa titin-associated protein) (M-protein) (Myomesin family member 2)MYOM2P542963
Myosin light chain 3 (Cardiac myosin light chain 1) (CMLC1) (Myosin light chain 1, slow-twitch muscle B/ventricular isoform) (MLC1SB) (Ventricular/slow twitch myosin alkali light chain)MYL3P085903
N(6)-adenine-specific DNA methyltransferase 2 (EC 2.1.1.-)N6AMT2Q8WVE03
N-acetylglucosamine-1-phosphotransferase subunit gamma (GlcNAc-1-phosphotransferase subunit gamma) (UDP-N-acetylglucosamine-1-phosphotransferase subunit gamma)GNPTG C16orf27 GNPTAG CAB56184 LP2537Q9UJJ93
N-acetyllactosaminide beta-1,6-N-acetylglucosaminyl-transferase, isoform A (N-acetylglucosaminyltransferase) (EC 2.4.1.150) (I-branching enzyme) (IGNT)GCNT2 GCNT5 II NACGT1Q8N0V53
N-alpha-acetyltransferase 15, NatA auxiliary subunit (Gastric cancer antigen Ga19) (N-terminal acetyltransferase) (NMDA receptor-regulated protein 1) (Protein tubedown-1) (Tbdn100)NAA15 GA19 NARG1 NATH TBDN100Q9BXJ93
N-alpha-acetyltransferase 35, NatC auxiliary subunit (Embryonic growth-associated protein homolog) (Protein MAK10 homolog)NAA35 EGAP MAK10Q5VZE53
N-alpha-acetyltransferase 38, NatC auxiliary subunit (U6 snRNA-associated Sm-like protein LSm8)NAA38 LSM8O957773
N-lysine methyltransferase SETD6 (EC 2.1.1.-) (SET domain-containing protein 6)SETD6Q8TBK23
N-lysine methyltransferase SMYD2 (EC 2.1.1.-) (HSKM-B) (Histone methyltransferase SMYD2) (EC 2.1.1.43) (Lysine N-methyltransferase 3C) (SET and MYND domain-containing protein 2)SMYD2 KMT3CQ9NRG43
N-methyl-D-aspartate receptor subunit 2D variant (Fragment)0Q59G173
NACHT, LRR and PYD domains-containing protein 3 (Angiotensin/vasopressin receptor AII/AVP-like) (Caterpiller protein 1.1) (CLR1.1) (Cold autoinflammatory syndrome 1 protein) (Cryopyrin) (PYRIN-containing APAF1-like protein 1)NLRP3 C1orf7 CIAS1 NALP3 PYPAF1Q96P203
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 4 (Hormone-regulated proliferation-associated protein of 20 kDa)NDUFAF4 C6orf66 HRPAP20 HSPC125 My013Q9P0323
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 (Complex I-19kD) (CI-19kD) (Complex I-PGIV) (CI-PGIV) (NADH-ubiquinone oxidoreductase 19 kDa subunit)NDUFA8P519703
NADH dehydrogenase [ubiquinone] iron-sulfur protein 5 (Complex I-15 kDa) (CI-15 kDa) (NADH-ubiquinone oxidoreductase 15 kDa subunit)NDUFS5O439203
NADH-ubiquinone oxidoreductase chain 2 (EC 1.6.5.3) (NADH dehydrogenase subunit 2)MT-ND2 MTND2 NADH2 ND2P038913
NADH-ubiquinone oxidoreductase chain 4 (EC 1.6.5.3) (NADH dehydrogenase subunit 4)MT-ND4 MTND4 NADH4 ND4P039053
NADH-ubiquinone oxidoreductase chain 6 (EC 1.6.5.3) (NADH dehydrogenase subunit 6)MT-ND6 MTND6 NADH6 ND6P039233
NADP-dependent oxidoreductase domain-containing protein 1 (EC 1.-.-.-) (Pyrroline-5-carboxylate reductase-like protein C14orf148)NOXRED1 C14orf148Q6NXP63
NADPH oxidase activator 1 (NOX activator 1) (Antigen NY-CO-31) (NCF2-like protein) (P67phox-like factor) (p51-nox)NOXA1 P51NOXQ86UR13
NADPH oxidase organizer 1 (NADPH oxidase regulatory protein) (Nox organizer 1) (Nox-organizing protein 1) (SH3 and PX domain-containing protein 5)NOXO1 P41NOX SH3PXD5Q8NFA23
Nance-Horan syndrome protein (Congenital cataracts and dental anomalies protein)NHSQ6T4R53
Nanos homolog 1 (NOS-1) (EC_Rep1a)NANOS1 NOS1Q8WY413
Nanos homolog 3 (NOS-3)NANOS3 NOS3P603233
Natural cytotoxicity triggering receptor 1 (Lymphocyte antigen 94 homolog) (NK cell-activating receptor) (Natural killer cell p46-related protein) (NK-p46) (NKp46) (hNKp46) (CD antigen CD335)NCR1 LY94O760363
Nck-associated protein 1 (NAP 1) (Membrane-associated protein HEM-2) (p125Nap1)NCKAP1 HEM2 KIAA0587 NAP1Q9Y2A73
NCK-interacting protein with SH3 domain (54 kDa VacA-interacting protein) (54 kDa vimentin-interacting protein) (VIP54) (90 kDa SH3 protein interacting with Nck) (AF3p21) (Dia-interacting protein 1) (DIP-1) (Diaphanous protein-interacting protein) (SH3 adapter protein SPIN90) (WASP-interacting SH3-domain protein) (WISH) (Wiskott-Aldrich syndrome protein-interacting protein)NCKIPSD AF3P21 SPIN90Q9NZQ33
NEDD4-like E3 ubiquitin-protein ligase WWP2 (EC 6.3.2.-) (Atrophin-1-interacting protein 2) (AIP2) (WW domain-containing protein 2)WWP2O003083
NEDD8-conjugating enzyme UBE2F (EC 6.3.2.-) (NEDD8 carrier protein UBE2F) (NEDD8 protein ligase UBE2F) (NEDD8-conjugating enzyme 2) (Ubiquitin-conjugating enzyme E2 F)UBE2F NCE2Q969M73
Netrin-1 (Epididymis tissue protein Li 131P)NTN1 NTN1LO956313
Neurexophilin-3NXPH3 KIAA1159 NPH3 UNQ687/PRO1327O951573
Neuroblastoma breakpoint family member 15NBPF15Q8N6603
Neuroblastoma RAS viral (V-ras) oncogene homolog (Neuroblastoma RAS viral (V-ras) oncogene homolog, isoform CRA_a)NRAS hCG_38454Q5U0913
Neurocalcin-deltaNCALDP616013
NeurochondrinNCDN KIAA0607Q9UBB63
Neurogenic locus notch homolog protein 1 (Notch 1) (hN1) (Translocation-associated notch protein TAN-1) [Cleaved into: Notch 1 extracellular truncation; Notch 1 intracellular domain (NICD)]NOTCH1 TAN1P465313
Neuromedin-B [Cleaved into: Neuromedin-B-32; Neuromedin-B]NMBP089493
Neuron-specific calcium-binding protein hippocalcin (Calcium-binding protein BDR-2)HPCA BDR2P840743
Neuron-specific protein family member 1 (Brain neuron cytoplasmic protein 1)NSG1 D4S234P428573
Neuronal acetylcholine receptor subunit alpha-7CHRNA7 NACHRA7P365443
Neuronal acetylcholine receptor subunit beta-2CHRNB2P177873
Neuronal PAS domain protein 2NPAS2A2I2P53
Neuronal PAS domain-containing protein 3 (Neuronal PAS3) (Basic-helix-loop-helix-PAS protein MOP6) (Class E basic helix-loop-helix protein 12) (bHLHe12) (Member of PAS protein 6) (PAS domain-containing protein 6)NPAS3 BHLHE12 MOP6 PASD6Q8IXF03
Neuropathy target esterase (EC 3.1.1.5) (Patatin-like phospholipase domain-containing protein 6)PNPLA6 NTEQ8IY173
Neuropeptide B (Preproprotein L7) (hPPL7) [Cleaved into: Neuropeptide B-23 (NPB23) (hL7); Neuropeptide B-29 (NPB29) (hL7C)]NPB PPL7 PPNPBQ8NG413
Neuropeptide W (Preproprotein L8) (hPPL8) [Cleaved into: Neuropeptide W-23 (NPW23) (hL8); Neuropeptide W-30 (NPW30) (hL8C)]NPW PPL8 PPNPWQ8N7293
Neuropilin and tolloid-like protein 2 (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 2)NETO2 BTCL2 UNQ1926/PRO4401Q8NC673
NeurturinNRTNQ997483
Neutrophil cytosol factor 1 (NCF-1) (47 kDa autosomal chronic granulomatous disease protein) (47 kDa neutrophil oxidase factor) (NCF-47K) (Neutrophil NADPH oxidase factor 1) (Nox organizer 2) (Nox-organizing protein 2) (SH3 and PX domain-containing protein 1A) (p47-phox)NCF1 NOXO2 SH3PXD1AP145983
Neutrophil elastase (EC 3.4.21.37) (Bone marrow serine protease) (Elastase-2) (Human leukocyte elastase) (HLE) (Medullasin) (PMN elastase)ELANE ELA2P082463
Neutrophil gelatinase-associated lipocalin (NGAL) (25 kDa alpha-2-microglobulin-related subunit of MMP-9) (Lipocalin-2) (Oncogene 24p3) (Siderocalin LCN2) (p25)LCN2 HNL NGALP801883
Next to BRCA1 gene 1 protein (Cell migration-inducing gene 19 protein) (Membrane component chromosome 17 surface marker 2) (Neighbor of BRCA1 gene 1 protein) (Protein 1A1-3B)NBR1 1A13B KIAA0049 M17S2 MIG19Q145963
NF-kappa-B inhibitor-interacting Ras-like protein 1 (I-kappa-B-interacting Ras-like protein 1) (Kappa B-Ras protein 1) (KappaB-Ras1)NKIRAS1 KBRAS1Q9NYS03
NF-kappa-B inhibitor-interacting Ras-like protein 2 (I-kappa-B-interacting Ras-like protein 2) (Kappa B-Ras protein 2) (KappaB-Ras2)NKIRAS2 KBRAS2Q9NYR93
NF-X1-type zinc finger protein NFXL1 (Ovarian zinc finger protein) (hOZFP)NFXL1 OZFPQ6ZNB63
NGFI-A-binding protein 1 (EGR-1-binding protein 1) (Transcriptional regulatory protein p54)NAB1Q135063
NHP2 non-histone chromosome protein 2-like 1 (S. cerevisiae) (NHP2 non-histone chromosome protein 2-like 1 (S. cerevisiae), isoform CRA_a) (NHP2L1 protein) (cDNA, FLJ92061, Homo sapiens NHP2 non-histone chromosome protein 2-like 1 (S.cerevisiae) (NHP2L1), mRNA)NHP2L1 hCG_41538Q6FHM63
Nicalin (Nicastrin-like protein)NCLNQ969V33
Nicotinamide mononucleotide adenylyltransferase 2 (NMN adenylyltransferase 2) (EC 2.7.7.1) (Nicotinate-nucleotide adenylyltransferase 2) (NaMN adenylyltransferase 2) (EC 2.7.7.18)NMNAT2 C1orf15 KIAA0479Q9BZQ43
Nicotinamide N-methyltransferase (EC 2.1.1.1)NNMTP402613
Nicotinamide riboside kinase 1 (NRK 1) (NmR-K 1) (EC 2.7.1.22) (Nicotinic acid riboside kinase 1) (EC 2.7.1.173) (Ribosylnicotinamide kinase 1) (RNK 1) (Ribosylnicotinic acid kinase 1)NMRK1 C9orf95 NRK1Q9NWW63
Ninein-like proteinNINL KIAA0980 NLPQ9Y2I63
Noelin (Neuronal olfactomedin-related ER localized protein) (Olfactomedin-1)OLFM1 NOE1 NOEL1Q997843
Noelin-2 (Olfactomedin-2)OLFM2 NOE2O958973
Non-lysosomal glucosylceramidase (NLGase) (EC 3.2.1.45) (Beta-glucocerebrosidase 2) (Beta-glucosidase 2) (Glucosylceramidase 2)GBA2 KIAA1605 AD035Q9HCG73
NTF2-related export protein 1 (Protein p15)NXT1Q9UKK63
Nuclear factor erythroid 2-related factor 3 (NF-E2-related factor 3) (NFE2-related factor 3) (Nuclear factor, erythroid derived 2, like 3)NFE2L3 NRF3Q9Y4A83
Nuclear factor interleukin-3-regulated protein (E4 promoter-binding protein 4) (Interleukin-3 promoter transcriptional activator) (Interleukin-3-binding protein 1) (Transcriptional activator NF-IL3A)NFIL3 E4BP4 IL3BP1Q166493
Nuclear pore complex protein Nup155 (155 kDa nucleoporin) (Nucleoporin Nup155)NUP155 KIAA0791O756943
Nuclear pore complex protein Nup214 (214 kDa nucleoporin) (Nucleoporin Nup214) (Protein CAN)NUP214 CAIN CAN KIAA0023P356583
Nuclear pore complex protein Nup98-Nup96 [Cleaved into: Nuclear pore complex protein Nup98 (98 kDa nucleoporin) (Nucleoporin Nup98) (Nup98); Nuclear pore complex protein Nup96 (96 kDa nucleoporin) (Nucleoporin Nup96) (Nup96)]NUP98 ADAR2P529483
Nuclear pore membrane glycoprotein 210 (Nuclear pore protein gp210) (Nuclear envelope pore membrane protein POM 210) (POM210) (Nucleoporin Nup210) (Pore membrane protein of 210 kDa)NUP210 KIAA0906 PSEC0245Q8TEM13
Nuclear prelamin A recognition factor (Iron-only hydrogenase-like protein 2) (IOP2)NARFQ9UHQ13
Nuclear receptor 2C2-associated protein (TR4 orphan receptor-associated 16 kDa protein)NR2C2AP TRA16Q86WQ03
Nuclear receptor coactivator 2 (NCoA-2) (Class E basic helix-loop-helix protein 75) (bHLHe75) (Transcriptional intermediary factor 2) (hTIF2)NCOA2 BHLHE75 TIF2Q155963
Nuclear receptor subfamily 2 group C member 1 (Orphan nuclear receptor TR2) (Testicular receptor 2)NR2C1 TR2P130563
Nuclear receptor subfamily 4 group A member 1 (Early response protein NAK1) (Nuclear hormone receptor NUR/77) (Nur77) (Orphan nuclear receptor HMR) (Orphan nuclear receptor TR3) (ST-59) (Testicular receptor 3)NR4A1 GFRP1 HMR NAK1P227363
Nuclear receptor-binding proteinNRBP1 BCON3 NRBPQ9UHY13
Nuclear receptor-interacting protein 1 (Nuclear factor RIP140) (Receptor-interacting protein 140)NRIP1P485523
Nuclear speckle splicing regulatory protein 1 (Coiled-coil domain-containing protein 55) (Nuclear speckle-related protein 70) (NSrp70)NSRP1 CCDC55 NSRP70Q9H0G53
Nuclear transcription factor Y subunit alpha (CAAT box DNA-binding protein subunit A) (Nuclear transcription factor Y subunit A) (NF-YA)NFYAP235113
Nuclear valosin-containing protein-like (NVLp) (Nuclear VCP-like protein)NVLO153813
Nucleolar protein 58 (Nucleolar protein 5)NOP58 NOL5 NOP5 HSPC120Q9Y2X33
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