EVpedia provide top 100+ EV markers, selected according to their identification number.
Based on EV proteomes, we defined the identification number of protein A as the number of datasets which contain protein A.
Therefore, proteins with higher identification numbers were more conserved.

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Protein name Gene symbol UniProt accession Identification number
Podoplanin (Aggrus) (Glycoprotein 36) (Gp36) (PA2.26 antigen) (T1-alpha) (T1A)PDPN GP36 PSEC0003 PSEC0025Q86YL73
Pogo transposable element with KRAB domainPOGK KIAA1513 LST003 SLTP003Q9P2153
Poliovirus receptor (Nectin-like protein 5) (NECL-5) (CD antigen CD155)PVR PVSP151513
Poly [ADP-ribose] polymerase 8 (PARP-8) (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 16) (ARTD16)PARP8Q8N3A83
Polycomb protein EED (hEED) (WD protein associating with integrin cytoplasmic tails 1) (WAIT-1)EEDO755303
Polycystic kidney disease protein 1-like 1 (PC1-like 1 protein) (Polycystin-1L1)PKD1L1 UNQ5785/PRO19563Q8TDX93
Polypeptide N-acetylgalactosaminyltransferase 11 (EC 2.4.1.41) (Polypeptide GalNAc transferase 11) (GalNAc-T11) (pp-GaNTase 11) (Protein-UDP acetylgalactosaminyltransferase 11) (UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 11)GALNT11Q8NCW63
Polypeptide N-acetylgalactosaminyltransferase 16 (EC 2.4.1.41) (Polypeptide GalNAc transferase-like protein 1) (GalNAc-T-like protein 1) (pp-GaNTase-like protein 1) (Polypeptide N-acetylgalactosaminyltransferase-like protein 1) (Protein-UDP acetylgalactosaminyltransferase-like protein 1) (UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase-like protein 1)GALNT16 GALNTL1 KIAA1130Q8N4283
Polypeptide N-acetylgalactosaminyltransferase 3 (EC 2.4.1.41) (Polypeptide GalNAc transferase 3) (GalNAc-T3) (pp-GaNTase 3) (Protein-UDP acetylgalactosaminyltransferase 3) (UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 3)GALNT3Q144353
POM121-like protein 12POM121L12Q8N7R13
Popeye domain-containing protein 3 (Popeye protein 3)POPDC3 POP3Q9HBV13
Potassium channel subfamily K member 1 (Inward rectifying potassium channel protein TWIK-1) (Potassium channel KCNO1)KCNK1 HOHO1 KCNO1 TWIK1O001803
Potassium voltage-gated channel subfamily A member 3 (HGK5) (HLK3) (HPCN3) (Voltage-gated K(+) channel HuKIII) (Voltage-gated potassium channel subunit Kv1.3)KCNA3 HGK5P220013
Potassium voltage-gated channel subfamily C member 2 (Voltage-gated potassium channel Kv3.2)KCNC2Q96PR13
Potassium voltage-gated channel subfamily H member 5 (Ether-a-go-go potassium channel 2) (hEAG2) (Voltage-gated potassium channel subunit Kv10.2)KCNH5 EAG2Q8NCM23
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3HCN3 KIAA1535Q9P1Z33
POTE ankyrin domain family member G (ANKRD26-like family C member 2) (Prostate, ovary, testis-expressed protein on chromosome 14) (POTE-14)POTEG A26C2 POTE14Q6S5H53
POU domain, class 2, transcription factor 2 (Lymphoid-restricted immunoglobulin octamer-binding protein NF-A2) (Octamer-binding protein 2) (Oct-2) (Octamer-binding transcription factor 2) (OTF-2)POU2F2 OCT2 OTF2P090863
POU domain, class 3, transcription factor 2 (Brain-specific homeobox/POU domain protein 2) (Brain-2) (Brn-2) (Nervous system-specific octamer-binding transcription factor N-Oct-3) (Octamer-binding protein 7) (Oct-7) (Octamer-binding transcription factor 7) (OTF-7)POU3F2 BRN2 OCT7 OTF7P202653
POZ-, AT hook-, and zinc finger-containing protein 1 (BTB/POZ domain zinc finger transcription factor) (Protein kinase A RI subunit alpha-associated protein) (Zinc finger and BTB domain-containing protein 19) (Zinc finger protein 278) (Zinc finger sarcoma gene protein)PATZ1 PATZ RIAZ ZBTB19 ZNF278 ZSGQ9HBE13
PRAME family member 5PRAMEF5Q5TYX03
Pre-mRNA-splicing factor RBM22 (RNA-binding motif protein 22) (Zinc finger CCCH domain-containing protein 16)RBM22 ZC3H16 199G4Q9NW643
Prefoldin subunit 2 (cDNA, FLJ96845, Homo sapiens prefoldin 2 (PFDN2), mRNA)PFDN2 hCG_1995291B1AQP23
Prenylcysteine oxidase 1 (EC 1.8.3.5) (Prenylcysteine lyase)PCYOX1 KIAA0908 PCL1 UNQ597/PRO1183Q9UHG33
Presenilin-2 (PS-2) (EC 3.4.23.-) (AD3LP) (AD5) (E5-1) (STM-2) [Cleaved into: Presenilin-2 NTF subunit; Presenilin-2 CTF subunit]PSEN2 AD4 PS2 PSNL2 STM2P498103
Prickle-like protein 2PRICKLE2Q7Z3G63
Probable 2-oxoglutarate dehydrogenase E1 component DHKTD1, mitochondrial (EC 1.2.4.2) (Dehydrogenase E1 and transketolase domain-containing protein 1)DHTKD1 KIAA1630Q96HY73
Probable aminopeptidase NPEPL1 (EC 3.4.11.-) (Aminopeptidase-like 1)NPEPL1 KIAA1974Q8NDH33
Probable ATP-dependent RNA helicase YTHDC2 (EC 3.6.4.13)YTHDC2Q9H6S03
Probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 (NADP-dependent methylenetetrahydrofolate dehydrogenase 2-like protein) (MTHFD2-like) [Includes: NAD-dependent methylenetetrahydrofolate dehydrogenase (EC 1.5.1.15); Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9)]MTHFD2LQ9H9033
Probable carboxypeptidase PM20D1 (EC 3.4.17.-) (Peptidase M20 domain-containing protein 1)PM20D1Q6GTS83
Probable dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase (EC 2.4.1.265) (Asparagine-linked glycosylation protein 8 homolog) (Dol-P-Glc:Glc(1)Man(9)GlcNAc(2)-PP-dolichyl alpha-1,3-glucosyltransferase) (Dolichyl-P-Glc:Glc1Man9GlcNAc2-PP-dolichyl glucosyltransferase)ALG8 HUSSY-02Q9BVK23
Probable E3 ubiquitin-protein ligase HERC1 (EC 6.3.2.-) (HECT domain and RCC1-like domain-containing protein 1) (p532) (p619)HERC1Q157513
Probable E3 ubiquitin-protein ligase RNF144A (EC 6.3.2.-) (RING finger protein 144A) (UbcM4-interacting protein 4) (Ubiquitin-conjugating enzyme 7-interacting protein 4)RNF144A KIAA0161 RNF144 UBCE7IP4P508763
Probable ergosterol biosynthetic protein 28C14orf1 AD-011 HSPC288 x0006Q9UKR53
Probable fibrosin-1FBRS FBS FBS1Q9HAH73
Probable G-protein coupled receptor 139 (G(q)-coupled orphan receptor GPRg1) (G-protein-coupled receptor PGR3)GPR139 GPRG1 PGR3Q6DWJ63
Probable G-protein coupled receptor 142 (G-protein coupled receptor PGR2)GPR142 PGR2Q7Z6013
Probable G-protein coupled receptor 156 (G-protein coupled receptor PGR28) (GABAB-related G-protein coupled receptor)GPR156 GABABL PGR28Q8NFN83
Probable G-protein coupled receptor 173 (Super conserved receptor expressed in brain 3)GPR173 SREB3Q9NS663
Probable methyltransferase-like protein 15 (EC 2.1.1.-) (Methyltransferase 5 domain-containing protein 1)METTL15 METT5D1A6NJ783
Probable palmitoyltransferase ZDHHC4 (EC 2.3.1.225) (Zinc finger DHHC domain-containing protein 4) (DHHC-4) (Zinc finger protein 374)ZDHHC4 ZNF374 DC1 UNQ5787/PRO19576Q9NPG83
Probable palmitoyltransferase ZDHHC8 (EC 2.3.1.225) (Zinc finger DHHC domain-containing protein 8) (DHHC-8) (Zinc finger protein 378)ZDHHC8 KIAA1292 ZDHHCL1 ZNF378Q9ULC83
Probable phospholipid-transporting ATPase IH (EC 3.6.3.1) (ATPase IS) (ATPase class VI type 11A)ATP11A ATPIH ATPIS KIAA1021P981963
Probable tRNA(His) guanylyltransferase (EC 2.7.7.79) (Interphase cytoplasmic foci protein 45) (tRNA-histidine guanylyltransferase)THG1L ICF45Q9NWX63
Probable Xaa-Pro aminopeptidase 3 (X-Pro aminopeptidase 3) (EC 3.4.11.9) (Aminopeptidase P3) (APP3)XPNPEP3Q9NQH73
Procollagen C-endopeptidase enhancer 1 (Procollagen COOH-terminal proteinase enhancer 1) (PCPE-1) (Procollagen C-proteinase enhancer 1) (Type 1 procollagen C-proteinase enhancer protein) (Type I procollagen COOH-terminal proteinase enhancer)PCOLCE PCPE1Q151133
Progestin and adipoQ receptor family member 3 (Progestin and adipoQ receptor family member III) (Raf kinase trapping to Golgi) (RKTG)PAQR3Q6TCH73
Programmed cell death protein 7 (ES18) (hES18)PDCD7Q8N8D13
Progressive ankylosis protein homolog (ANK)ANKH KIAA1581 UNQ241/PRO274Q9HCJ13
Prolactin releasing hormone (Putative uncharacterized protein PRH)PRH PRLH hCG_23020Q53QV73
Proline-rich protein 12PRR12 KIAA1205Q9ULL53
Proline-rich protein 23BPRR23BQ6ZRT63
Proline-rich protein 5-like (Protein observed with Rictor-2) (Protor-2)PRR5L PROTOR2Q6MZQ03
Proline-rich protein PRCC (Papillary renal cell carcinoma translocation-associated gene protein)PRCC TPRCQ927333
Proline-rich transmembrane protein 2 (Dispanin subfamily B member 3) (DSPB3)PRRT2Q7Z6L03
Prominin-1 (Antigen AC133) (Prominin-like protein 1) (CD antigen CD133)PROM1 PROML1 MSTP061O434903
Propionyl-CoA carboxylase alpha chain, mitochondrial (PCCase subunit alpha) (EC 6.4.1.3) (Propanoyl-CoA:carbon dioxide ligase subunit alpha)PCCAP051653
Proprotein convertase subtilisin/kexin type 9 (EC 3.4.21.-) (Neural apoptosis-regulated convertase 1) (NARC-1) (Proprotein convertase 9) (PC9) (Subtilisin/kexin-like protease PC9)PCSK9 NARC1 PSEC0052Q8NBP73
Prostaglandin D2 receptor 2 (Chemoattractant receptor-homologous molecule expressed on Th2 cells) (G-protein coupled receptor 44) (CD antigen CD294)PTGDR2 CRTH2 DL1R GPR44Q9Y5Y43
Prostaglandin E synthase 2 (EC 5.3.99.3) (Microsomal prostaglandin E synthase 2) (mPGES-2) [Cleaved into: Prostaglandin E synthase 2 truncated form]PTGES2 C9orf15 PGES2Q9H7Z73
Prostaglandin E2 receptor EP3 subtype (PGE receptor EP3 subtype) (PGE2 receptor EP3 subtype) (PGE2-R) (Prostanoid EP3 receptor)PTGER3P431153
Prostate androgen-regulated mucin-like protein 1 (PARM-1)PARM1 UNQ1879/PRO4322Q6UWI23
Prostate-specific antigen (PSA) (EC 3.4.21.77) (Gamma-seminoprotein) (Seminin) (Kallikrein-3) (P-30 antigen) (Semenogelase)KLK3 APSP072883
Prostatic acid phosphatase (PAP) (EC 3.1.3.2) (5'-nucleotidase) (5'-NT) (EC 3.1.3.5) (Ecto-5'-nucleotidase) (Thiamine monophosphatase) (TMPase) [Cleaved into: PAPf39]ACPPP153093
Protachykinin-1 (PPT) [Cleaved into: Substance P; Neurokinin A (NKA) (Neuromedin L) (Substance K); Neuropeptide K (NPK); Neuropeptide gamma; C-terminal-flanking peptide]TAC1 NKA NKNA TAC2P203663
Protamine-3 (Sperm protamine P3)PRM3Q9NNZ63
Proteasome (Prosome, macropain) 26S subunit, ATPase, 1 (Proteasome (Prosome, macropain) 26S subunit, ATPase, 1, isoform CRA_a) (Proteasome 26S ATPase subunit 1) (cDNA, FLJ93843, Homo sapiens proteasome (prosome, macropain) 26S subunit, ATPase, 1(PSMC1), mRNA)PSMC1 hCG_2029049Q53XL83
Proteasome (Prosome, macropain) 26S subunit, ATPase, 4, isoform CRA_b (cDNA FLJ78505, highly similar to Homo sapiens proteasome (prosome, macropain) 26S subunit, ATPase, 4 (PSMC4), transcript variant 1, mRNA) (cDNA, FLJ93682, Homo sapiens proteasome (prosome, macropain) 26S subunit, ATPase, 4(PSMC4), transcript variant 1, mRNA)PSMC4 hCG_43346A8K2M03
Proteasome subunit beta type (EC 3.4.25.1)PSMB6 hCG_32695Q6IAT93
Protein 4.1 (P4.1) (4.1R) (Band 4.1) (EPB4.1)EPB41 E41PP111713
Protein AF-9 (ALL1-fused gene from chromosome 9 protein) (Myeloid/lymphoid or mixed-lineage leukemia translocated to chromosome 3 protein) (YEATS domain-containing protein 3)MLLT3 AF9 YEATS3P425683
Protein arginine N-methyltransferase 3 (EC 2.1.1.-) (Heterogeneous nuclear ribonucleoprotein methyltransferase-like protein 3)PRMT3 HRMT1L3O606783
Protein argonaute-1 (Argonaute1) (hAgo1) (Argonaute RISC catalytic component 1) (Eukaryotic translation initiation factor 2C 1) (eIF-2C 1) (eIF2C 1) (Putative RNA-binding protein Q99)AGO1 EIF2C1Q9UL183
Protein BANP (BEN domain-containing protein 1) (Btg3-associated nuclear protein) (Scaffold/matrix-associated region-1-binding protein)BANP BEND1 SMAR1Q8N9N53
Protein C-ets-2ETS2P150363
Protein canopy homolog 3 (CTG repeat protein 4a) (Expanded repeat-domain protein CAG/CTG 5) (Protein associated with TLR4) (Trinucleotide repeat-containing gene 5 protein)CNPY3 CTG4A ERDA5 PRAT4A TNRC5 HSPC084 UNQ1934/PRO4409Q9BT093
Protein canopy homolog 4CNPY4 PSEC0237 UNQ1909/PRO4354Q8N1293
Protein CBFA2T1 (Cyclin-D-related protein) (Eight twenty one protein) (Protein ETO) (Protein MTG8) (Zinc finger MYND domain-containing protein 2)RUNX1T1 AML1T1 CBFA2T1 CDR ETO MTG8 ZMYND2Q064553
Protein DBF4 homolog A (Activator of S phase kinase) (Chiffon homolog A) (DBF4-type zinc finger-containing protein 1)DBF4 ASK DBF4A ZDBF1Q9UBU73
Protein DGCR6L (DiGeorge syndrome critical region 6-like protein)DGCR6LQ9BY273
Protein disulfide-isomerase A3 (EC 5.3.4.1) (58 kDa glucose-regulated protein) (58 kDa microsomal protein) (p58) (Disulfide isomerase ER-60) (Endoplasmic reticulum resident protein 57) (ER protein 57) (ERp57) (Endoplasmic reticulum resident protein 60) (ER protein 60) (ERp60)PDIA3 ERP57 ERP60 GRP58P301013
Protein DosC19orf26K7EJP23
Protein FAM101AFAM101AQ6ZTI63
Protein FAM110BFAM110B C8orf72Q8TC763
Protein FAM110CFAM110CQ1W6H93
Protein FAM117A (C/EBP-induced protein)FAM117AQ9C0733
Protein FAM117B (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 13 protein)FAM117B ALS2CR13Q6P1L53
Protein FAM122BFAM122BQ7Z3093
Protein FAM127C (Mammalian retrotransposon derived protein 8B)FAM127C CXX1C MAR8BQ17RB03
Protein FAM134CFAM134CQ86VR23
Protein FAM149AFAM149A MST119A5PLN73
Protein FAM156A/FAM156B (Transmembrane protein 29/29B)FAM156A TMEM29 PP12994 PRO0659; FAM156B TMEM29BQ8NDB63
Protein FAM179BFAM179B KIAA0423Q9Y4F43
Protein FAM188BFAM188B C7orf67Q4G0A63
Protein FAM196AFAM196A C10orf141Q6ZSG23
Protein FAM19A5 (Chemokine-like protein TAFA-5)FAM19A5 TAFA5 UNQ5208/PRO34524Q7Z5A73
Protein FAM204AFAM204A C10orf84Q9H8W33
Protein FAM206AFAM206A C9orf6Q9NX383
Protein FAM208A (CTCL tumor antigen se89-1) (Retinoblastoma-associated protein RAP140)FAM208A C3orf63 KIAA1105Q9UK613
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