EVpedia provide top 100+ EV markers, selected according to their identification number.
Based on EV proteomes, we defined the identification number of protein A as the number of datasets which contain protein A.
Therefore, proteins with higher identification numbers were more conserved.

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Protein name Gene symbol UniProt accession Identification number
Protein FAM212BFAM212B C1orf183Q9NTI73
Protein FAM220A (STAT3-interacting protein as a repressor)FAM220A C7orf70 SIPARQ7Z4H93
Protein FAM3DFAM3D UNQ567/PRO1130Q96BQ13
Protein FAM43AFAM43A PP7298Q8N2R83
Protein FAM46BFAM46BQ96A093
Protein FAM57A (Protein CT120)FAM57AQ8TBR73
Protein FAM76BFAM76BQ5HYJ33
Protein FAM83D (Spindle protein CHICA)FAM83D C20orf129Q9H4H83
Protein FAM83EFAM83EQ2M2I33
Protein FAM86B1FAM86B1Q8N7N13
Protein FAM91A1FAM91A1Q658Y43
Protein GREB1 (Gene regulated in breast cancer 1 protein)GREB1 KIAA0575Q4ZG553
Protein GTLF3BGTLF3B C17orf103Q8N6N63
Protein Hook homolog 2 (h-hook2) (hHK2)HOOK2Q96ED93
Protein KASH5 (Coiled-coil domain-containing protein 155) (KASH domain-containing protein 5)CCDC155 KASH5Q8N6L03
Protein kinase C eta type (EC 2.7.11.13) (PKC-L) (nPKC-eta)PRKCH PKCL PRKCLP247233
Protein kinase C zeta type (EC 2.7.11.13) (nPKC-zeta)PRKCZ PKC2Q055133
Protein LCHNLCHN KIAA1147A4D1U43
Protein lifeguard 1 (Glutamate [NMDA] receptor-associated protein 1) (NMDA receptor glutamate-binding subunit) (Putative MAPK-activating protein PM02) (Transmembrane BAX inhibitor motif-containing protein 3)GRINA LFG1 NMDARA1 TMBIM3Q7Z4293
Protein lifeguard 2 (Fas apoptotic inhibitory molecule 2) (Neural membrane protein 35) (Transmembrane BAX inhibitor motif-containing protein 2)FAIM2 KIAA0950 LFG LFG2 NMP35 TMBIM2Q9BWQ83
Protein lifeguard 3 (Protein RECS1 homolog) (Transmembrane BAX inhibitor motif-containing protein 1)TMBIM1 LFG3 RECS1 PP1201 PSEC0158Q969X13
Protein lin-28 homolog A (Lin-28A) (Zinc finger CCHC domain-containing protein 1)LIN28A CSDD1 LIN28 ZCCHC1Q9H9Z23
Protein LZIC (Leucine zipper and CTNNBIP1 domain-containing protein) (Leucine zipper and ICAT homologous domain-containing protein)LZICQ8WZA03
Protein MAATS1 (AMY-1-associating protein expressed in testis 1) (AAT-1) (MYCBP/AMY-1-associated testis-expressed protein 1)MAATS1 AAT1 C3orf15Q7Z4T93
Protein mab-21-like 2MAB21L2Q9Y5863
Protein Mdm4 (Double minute 4 protein) (Mdm2-like p53-binding protein) (Protein Mdmx) (p53-binding protein Mdm4)MDM4 MDMXO151513
Protein Mis18-alpha (FAPP1-associated protein 1)MIS18A C21orf45 C21orf46 FASP1Q9NYP93
Protein naked cuticle homolog 1 (Naked-1) (hNkd) (hNkd1)NKD1 NKD PP7246Q969G93
Protein NDRG4 (Brain development-related molecule 1) (N-myc downstream-regulated gene 4 protein) (Vascular smooth muscle cell-associated protein 8) (SMAP-8)NDRG4 BDM1 KIAA1180Q9ULP03
Protein Njmu-R1C17orf75Q9HAS03
Protein NPAT (Nuclear protein of the ataxia telangiectasia mutated locus) (Nuclear protein of the ATM locus) (p220)NPAT CAND3 E14Q142073
Protein O-linked-mannose beta-1,4-N-acetylglucosaminyltransferase 2 (POMGnT2) (EC 2.4.1.-) (Extracellular O-linked N-acetylglucosamine transferase-like) (Glycosyltransferase-like domain-containing protein 2)POMGNT2 AGO61 C3orf39 EOGTL GTDC2Q8NAT13
Protein orai-3 (Transmembrane protein 142C)ORAI3 TMEM142CQ9BRQ53
Protein PBDC1 (Polysaccharide biosynthesis domain-containing protein 1)PBDC1 CXorf26Q9BVG43
Protein phosphatase 1 regulatory subunit 12C (Protein phosphatase 1 myosin-binding subunit of 85 kDa) (Protein phosphatase 1 myosin-binding subunit p85)PPP1R12C LENG3 MBS85Q9BZL43
Protein phosphatase 1 regulatory subunit 3C (Protein phosphatase 1 regulatory subunit 5) (PP1 subunit R5) (Protein targeting to glycogen) (PTG)PPP1R3C PPP1R5Q9UQK13
Protein phosphatase Slingshot homolog 3 (EC 3.1.3.16) (EC 3.1.3.48) (SSH-like protein 3) (SSH-3L) (hSSH-3L)SSH3 SSH3LQ8TE773
Protein pitchforkPIFO C1orf88Q8TCI53
Protein regulator of cytokinesis 1PRC1O436633
Protein RRNAD1 (Ribosomal RNA adenine dimethylase domain-containing protein 1)RRNAD1 C1orf66 CGI-41Q96FB53
Protein RRP5 homolog (NF-kappa-B-binding protein) (NFBP) (Programmed cell death protein 11)PDCD11 KIAA0185Q146903
Protein S100-A9 (Calgranulin-B) (Calprotectin L1H subunit) (Leukocyte L1 complex heavy chain) (Migration inhibitory factor-related protein 14) (MRP-14) (p14) (S100 calcium-binding protein A9)S100A9 CAGB CFAG MRP14P067023
Protein S100-B (S-100 protein beta chain) (S-100 protein subunit beta) (S100 calcium-binding protein B)S100BP042713
Protein SCO1 homolog, mitochondrialSCO1 SCOD1O758803
Protein shisa-7 (Protein shisa-6-like)SHISA7A6NL883
Protein Shroom2 (Apical-like protein) (Protein APXL)SHROOM2 APXLQ137963
Protein Shroom3 (Shroom-related protein) (hShrmL)SHROOM3 KIAA1481 SHRML MSTP013Q8TF723
Protein slowmo homolog 2SLMO2 C20orf45 CGI-107Q9Y3B13
Protein SLX4IP (SLX4-interacting protein)SLX4IP C20orf94Q5VYV73
Protein Smaug homolog 2 (Smaug 2) (hSmaug2) (Sterile alpha motif domain-containing protein 4B) (SAM domain-containing protein 4B)SAMD4B SMAUG2Q5PRF93
Protein SMG9 (Protein smg-9 homolog)SMG9 C19orf61Q9H0W83
Protein SOGA2 (Coiled-coil domain-containing protein 165)SOGA2 CCDC165 KIAA0802Q9Y4B53
Protein SYS1 homologSYS1 C20orf169Q8N2H43
Protein TANC2 (Tetratricopeptide repeat, ankyrin repeat and coiled-coil domain-containing protein 2)TANC2 KIAA1148 KIAA1636Q9HCD63
Protein TBRG4 (Cell cycle progression restoration protein 2) (Cell cycle progression protein 2) (FAST kinase domain-containing protein 4) (Transforming growth factor beta regulator 4)TBRG4 CPR2 FASTKD4 KIAA0948Q969Z03
Protein THEM6 (Mesenchymal stem cell protein DSCD75) (Thioesterase superfamily member 6)THEM6 C8orf55 PSEC0098Q8WUY13
Protein timeless homolog (hTIM)TIMELESS TIM TIM1 TIMELESS1Q9UNS13
Protein TSSC1 (Tumor-suppressing STF cDNA 1 protein) (Tumor-suppressing subchromosomal transferable fragment candidate gene 1 protein)TSSC1Q53HC93
Protein turtle homolog A (Immunoglobulin superfamily member 9A) (IgSF9A)IGSF9 IGSF9A KIAA1355 NRT1Q9P2J23
Protein unc-119 homolog A (Retinal protein 4) (hRG4)UNC119 RG4Q134323
Protein unc-119 homolog BUNC119BA6NIH73
Protein unc-13 homolog B (Munc13-2) (munc13)UNC13B UNC13O147953
Protein VPRBP (DDB1- and CUL4-associated factor 1) (HIV-1 Vpr-binding protein) (VprBP) (Vpr-interacting protein)VPRBP DCAF1 KIAA0800 RIPQ9Y4B63
Protein Wnt0Q8N2E53
Protein Wnt-10b (Protein Wnt-12)WNT10B WNT12O007443
Protein Wnt-7bWNT7BP567063
Protein wntless homolog (Integral membrane protein GPR177) (Protein evenness interrupted homolog) (EVI) (Putative NF-kappa-B-activating protein 373)WLS C1orf139 GPR177 UNQ85/PRO18667Q5T9L33
Protein XRP2RP2O756953
Protein YIF1A (54TMp) (YIP1-interacting factor homolog A)YIF1A 54TM HYIF1P YIF1O950703
Protein YIPF5 (Five-pass transmembrane protein localizing in the Golgi apparatus and the endoplasmic reticulum 5) (Smooth muscle cell-associated protein 5) (SMAP-5) (YIP1 family member 5) (YPT-interacting protein 1 A)YIPF5 FINGER5 YIP1A PP12723 SB140 UNQ3123/PRO10275Q969M33
Protein ZBED8 (Transposon-derived Buster3 transposase-like protein) (Zinc finger BED domain-containing protein 8)ZBED8 Buster3 C5orf54Q8IZ133
Protein-glutamine gamma-glutamyltransferase 4 (EC 2.3.2.13) (Fibrinoligase) (Prostate transglutaminase) (Prostate-specific transglutaminase) (Transglutaminase P) (TG(P)) (TGP) (TGase P) (Transglutaminase-4) (TGase-4)TGM4P492213
Protein-lysine 6-oxidase (EC 1.4.3.13) (Lysyl oxidase)LOXP283003
Protein-methionine sulfoxide oxidase MICAL1 (EC 1.14.13.-) (Molecule interacting with CasL protein 1) (MICAL-1) (NEDD9-interacting protein with calponin homology and LIM domains)MICAL1 MICAL NICALQ8TDZ23
Proto-oncogene c-Fos (Cellular oncogene fos) (G0/G1 switch regulatory protein 7)FOS G0S7P011003
Proto-oncogene Wnt-1 (Proto-oncogene Int-1 homolog)WNT1 INT1P046283
Protocadherin Fat 1 (Cadherin family member 7) (Cadherin-related tumor suppressor homolog) (Protein fat homolog) [Cleaved into: Protocadherin Fat 1, nuclear form]FAT1 CDHF7 FATQ145173
Protocadherin gamma-A4 (PCDH-gamma-A4)PCDHGA4Q9Y5G93
Protogenin (Protein Shen-Dan)PRTGQ2VWP73
Protransforming growth factor alpha [Cleaved into: Transforming growth factor alpha (TGF-alpha) (EGF-like TGF) (ETGF) (TGF type 1)]TGFAP011353
Pulmonary surfactant-associated protein D (PSP-D) (SP-D) (Collectin-7) (Lung surfactant protein D)SFTPD COLEC7 PSPD SFTP4P352473
Putative chondrosarcoma-associated gene 1 protein (Cancer/testis antigen 24.1) (CT24.1) (Cancer/testis antigen CSAGE)CSAG1 CSAGEQ6PB303
Putative E3 ubiquitin-protein ligase SH3RF2 (EC 6.3.2.-) (Heart protein phosphatase 1-binding protein) (HEPP1) (Protein phosphatase 1 regulatory subunit 39) (RING finger protein 158) (SH3 domain-containing RING finger protein 2)SH3RF2 PPP1R39 RNF158Q8TEC53
Putative GTP cyclohydrolase 1 type 2 NIF3L1 (EC 3.5.4.16) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 1 protein) (GTP cyclohydrolase I) (NIF3-like protein 1)NIF3L1 ALS2CR1 MDS015 My018Q9GZT83
Putative homeodomain transcription factor 1PHTF1 PHTFQ9UMS53
Putative hydroxypyruvate isomerase (EC 5.3.1.22) (Endothelial cell apoptosis protein E-CE1)HYI HT036 SB156Q5T0133
Putative methyl-CpG-binding domain protein 3-like 5 (MBD3-like protein 5)MBD3L5A6NJ083
Putative methyltransferase NSUN6 (EC 2.1.1.-) (NOL1/NOP2/Sun and PUA domain-containing protein 1) (NOL1/NOP2/Sun domain family member 6)NSUN6 NOPD1Q8TEA13
Putative N-acetyltransferase 16 (EC 2.3.1.-)NAT16 C7orf52Q8N8M03
Putative Polycomb group protein ASXL1 (Additional sex combs-like protein 1)ASXL1 KIAA0978Q8IXJ93
Putative POTE ankyrin domain family member MPOTEMA6NI473
Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX32 (EC 3.6.4.13) (DEAD/H box 32) (DEAD/H helicase-like protein 1) (DHLP1) (DEAH box protein 32) (HuDDX32)DHX32 DDX32Q7L7V13
Putative protein arginine N-methyltransferase 10 (EC 2.1.1.-)PRMT10Q6P2P23
Putative protein FAM47CFAM47CQ5HY643
Putative RNA-binding protein Luc7-like 1 (Putative SR protein LUC7B1) (SR+89)LUC7L LUC7L1Q9NQ293
Putative serine protease 41 (EC 3.4.21.-) (Testis serine protease 1) (TESSP-1)PRSS41 TESSP1Q7RTY93
Putative tyrosine-protein phosphatase auxilin (EC 3.1.3.48) (DnaJ homolog subfamily C member 6)DNAJC6 KIAA0473O750613
Putative uncharacterized protein0Q8NHH23
Putative uncharacterized protein C19orf73C19orf73Q9NVV23
Putative uncharacterized protein DKFZp451O0517 (Fragment)DKFZp451O0517Q86T743
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