EVpedia provide top 100+ EV markers, selected according to their identification number.
Based on EV proteomes, we defined the identification number of protein A as the number of datasets which contain protein A.
Therefore, proteins with higher identification numbers were more conserved.

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Protein name Gene symbol UniProt accession Identification number
Putative uncharacterized protein DKFZp564P2062 (Fragment)DKFZp564P2062Q9Y4T03
Putative uncharacterized protein MYCN (V-myc myelocytomatosis viral related oncogene, neuroblastoma derived (Avian)) (V-myc myelocytomatosis viral related oncogene, neuroblastoma derived (Avian), isoform CRA_a)MYCN hCG_1783900Q53XS53
Putative uncharacterized protein ORF4ORF4Q9NQC53
Putative uncharacterized protein pp6425pp6425Q8WYU63
Putative uncharacterized protein RDH14 (Retinol dehydrogenase 14 (All-trans and 9-cis), isoform CRA_a) (cDNA, FLJ95921, Homo sapiens retinol dehydrogenase 14 (all-trans and 9-cis)(RDH14), mRNA)RDH14 hCG_1641437Q53RX33
Pyroglutamyl-peptidase 1 (EC 3.4.19.3) (5-oxoprolyl-peptidase) (Pyroglutamyl aminopeptidase I) (PAP-I) (Pyroglutamyl-peptidase I) (PGP-I) (Pyrrolidone-carboxylate peptidase)PGPEP1 PGPIQ9NXJ53
Pyruvate dehydrogenase protein X component, mitochondrial (Dihydrolipoamide dehydrogenase-binding protein of pyruvate dehydrogenase complex) (E3-binding protein) (E3BP) (Lipoyl-containing pyruvate dehydrogenase complex component X) (proX)PDHX PDX1O003303
Pyruvate kinase PKLR (EC 2.7.1.40) (Pyruvate kinase 1) (Pyruvate kinase isozymes L/R) (R-type/L-type pyruvate kinase) (Red cell/liver pyruvate kinase)PKLR PK1 PKLP306133
Rab proteins geranylgeranyltransferase component A 1 (Choroideremia protein) (Rab escort protein 1) (REP-1) (TCD protein)CHM REP1 TCDP243863
Rab proteins geranylgeranyltransferase component A 2 (Choroideremia-like protein) (Rab escort protein 2) (REP-2)CHML REP2P263743
Rab-like protein 2ARABL2AQ9UBK73
Rab-like protein 5RABL5Q9H7X73
RAD51-associated protein 1 (RAD51-interacting protein)RAD51AP1 PIR51Q96B013
RAD52 homolog (S. cerevisiae), isoform CRA_c (Rhabdomyosarcoma antigen MU-RMS-40.23) (cDNA FLJ77029, highly similar to Homo sapiens RAD52 homolog (S. cerevisiae) (RAD52), transcript variant alpha, mRNA)RAD52 hCG_25272Q5DR823
RAD9, HUS1, RAD1-interacting nuclear orphan protein 1 (RAD9, RAD1, HUS1-interacting nuclear orphan protein)RHNO1 C12orf32 RHINO HKMT1188Q9BSD33
RadixinRDXP352413
Ragulator complex protein LAMTOR4 (Late endosomal/lysosomal adaptor and MAPK and MTOR activator 4) [Cleaved into: Ragulator complex protein LAMTOR4, N-terminally processed]LAMTOR4 C7orf59Q0VGL13
Ral GTPase-activating protein subunit alpha-2 (250 kDa substrate of Akt) (AS250) (p220)RALGAPA2 C20orf74 KIAA1272Q2PPJ73
RanBP2-like and GRIP domain-containing protein 4RGPD4 RGP4Q7Z3J33
Ras and Rab interactor 2 (Ras association domain family 4) (Ras inhibitor JC265) (Ras interaction/interference protein 2)RIN2 RASSF4Q8WYP33
Ras association domain-containing protein 4RASSF4 AD037Q9H2L53
Ras association domain-containing protein 5 (New ras effector 1) (Regulator for cell adhesion and polarization enriched in lymphoid tissues) (RAPL)RASSF5 NORE1 RAPLQ8WWW03
Ras GTPase-activating-like protein IQGAP3IQGAP3Q86VI33
Ras-like protein family member 12 (Ras-like protein Ris)RASL12 RISQ9NYN13
Ras-related protein Rab-10RAB10P610263
Ras-related protein Rab-21RAB21 KIAA0118Q9UL253
Ras-related protein Rab-23RAB23 HSPC137Q9ULC33
Ras-related protein Rab-26RAB26Q9ULW53
Ras-related protein Rab-35 (GTP-binding protein RAY) (Ras-related protein Rab-1C)RAB35 RAB1C RAYQ152863
Ras-related protein Rab-39BRAB39BQ96DA23
Ras-related protein Rab-3DRAB3D GOV RAB16O957163
Ras-related protein Rab-43 (Ras-related protein Rab-41)RAB43 RAB41Q86YS63
Ras-related protein Rab-6BRAB6BQ9NRW13
Ras-related protein Rab-6C (Rab6-like protein WTH3)RAB6C WTH3Q9H0N03
Ras-related protein Rab-9ARAB9A RAB9P511513
Ras-related protein Rap-2cRAP2CQ9Y3L53
Ras-specific guanine nucleotide-releasing factor RalGPS1 (Ral GEF with PH domain and SH3-binding motif 1) (Ral guanine nucleotide exchange factor 2) (RalGEF 2) (RalA exchange factor RalGPS1)RALGPS1 KIAA0351 RALGEF2Q5JS133
RB-associated KRAB zinc finger protein (RB-associated KRAB repressor) (hRBaK) (Zinc finger protein 769)RBAK ZNF769Q9NYW83
Receptor activity-modifying protein 2 (Calcitonin-receptor-like receptor activity-modifying protein 2) (CRLR activity-modifying protein 2)RAMP2O608953
Receptor-type tyrosine-protein phosphatase alpha (Protein-tyrosine phosphatase alpha) (R-PTP-alpha) (EC 3.1.3.48)PTPRA PTPA PTPRL2P184333
Receptor-type tyrosine-protein phosphatase O (R-PTP-O) (EC 3.1.3.48) (Glomerular epithelial protein 1) (Protein tyrosine phosphatase U2) (PTP-U2) (PTPase U2)PTPRO GLEPP1 PTPU2Q168273
Regulator of chromosome condensation (Cell cycle regulatory protein) (Chromosome condensation protein 1)RCC1 CHC1P187543
Regulator of G-protein signaling 16 (RGS16) (A28-RGS14P) (Retinal-specific RGS) (RGS-r) (hRGS-r) (Retinally abundant regulator of G-protein signaling)RGS16 RGSRO154923
Regulator of G-protein signaling 5 (RGS5)RGS5O155393
RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (NFkB-interacting protein 1) (PPP1R13B-like protein)PPP1R13L IASPP NKIP1 PPP1R13BL RAIQ8WUF53
Relaxin-3 (Insulin-like peptide INSL7) (Insulin-like peptide 7) (Prorelaxin H3) [Cleaved into: Relaxin-3 B chain; Relaxin-3 A chain]RLN3 INSL7 RXN3 ZINS4 UNQ6188/PRO20213Q8WXF33
Replication factor C subunit 2 (Activator 1 40 kDa subunit) (A1 40 kDa subunit) (Activator 1 subunit 2) (Replication factor C 40 kDa subunit) (RF-C 40 kDa subunit) (RFC40)RFC2P352503
Reprimo-like proteinRPRMLQ8N4K43
Resistin (Adipose tissue-specific secretory factor) (ADSF) (C/EBP-epsilon-regulated myeloid-specific secreted cysteine-rich protein) (Cysteine-rich secreted protein A12-alpha-like 2) (Cysteine-rich secreted protein FIZZ3)RETN FIZZ3 HXCP1 RSTN UNQ407/PRO1199Q9HD893
REST corepressor 3RCOR3 KIAA1343Q9P2K33
Retinol dehydrogenase 11 (EC 1.1.1.300) (Androgen-regulated short-chain dehydrogenase/reductase 1) (HCV core-binding protein HCBP12) (Prostate short-chain dehydrogenase/reductase 1) (Retinal reductase 1) (RalR1)RDH11 ARSDR1 PSDR1 CGI-82Q8TC123
Retinol-binding protein 1 (Cellular retinol-binding protein) (CRBP) (Cellular retinol-binding protein I) (CRBP-I)RBP1 CRBP1P094553
Rho GTPase-activating protein 21 (Rho GTPase-activating protein 10) (Rho-type GTPase-activating protein 21)ARHGAP21 ARHGAP10 KIAA1424Q5T5U33
Rho GTPase-activating protein 22 (Rho-type GTPase-activating protein 22)ARHGAP22 RHOGAP2Q7Z5H33
Rho GTPase-activating protein 25 (Rho-type GTPase-activating protein 25)ARHGAP25 KIAA0053P423313
Rho GTPase-activating protein 39ARHGAP39 KIAA1688Q9C0H53
Rho GTPase-activating protein 4 (Rho-GAP hematopoietic protein C1) (Rho-type GTPase-activating protein 4) (p115)ARHGAP4 KIAA0131 RGC1 RHOGAP4P981713
Rho GTPase-activating protein 5 (Rho-type GTPase-activating protein 5) (p190-B)ARHGAP5 RHOGAP5Q130173
Rho guanine nucleotide exchange factor 37ARHGEF37A1IGU53
Rho guanine nucleotide exchange factor 5 (Ephexin-3) (Guanine nucleotide regulatory protein TIM) (Oncogene TIM) (Transforming immortalized mammary oncogene) (p60 TIM)ARHGEF5 TIMQ127743
Rho-related GTP-binding protein RhoE (Protein MemB) (Rho family GTPase 3) (Rho-related GTP-binding protein Rho8) (Rnd3)RND3 ARHE RHO8 RHOEP615873
Rhophilin-2 (76 kDa RhoB effector protein) (GTP-Rho-binding protein 2) (p76RBE)RHPN2Q8IUC43
Ribonuclease P protein subunit p21 (RNaseP protein p21) (EC 3.1.26.5) (Ribonuclease P/MRP 21 kDa subunit) (Ribonucleoprotein V)RPP21 C6orf135 CAT60Q9H6333
Ribonuclease pancreatic (EC 3.1.27.5) (HP-RNase) (RIB-1) (RNase UpI-1) (Ribonuclease 1) (RNase 1) (Ribonuclease A) (RNase A)RNASE1 RIB1 RNS1P079983
Ribonuclease UK114 (EC 3.1.-.-) (14.5 kDa translational inhibitor protein) (p14.5) (Heat-responsive protein 12) (UK114 antigen homolog)HRSP12 PSPP527583
Ribosomal protein S6 kinase delta-1 (S6K-delta-1) (EC 2.7.11.1) (52 kDa ribosomal protein S6 kinase) (Ribosomal S6 kinase-like protein with two PSK domains 118 kDa protein) (SPHK1-binding protein)RPS6KC1 RPK118Q96S383
RING finger and transmembrane domain-containing protein 1 (Protein PTD016)RNFT1 PTD016Q5M7Z03
RING finger protein 113A (Zinc finger protein 183)RNF113A RNF113 ZNF183O155413
RING finger protein 121RNF121Q9H9203
RING finger protein 37 (U-box domain-containing protein 5) (Ubiquitin-conjugating enzyme 7-interacting protein 5)UBOX5 KIAA0860 RNF37 UBCE7IP5O949413
RNA exonuclease 1 homolog (EC 3.1.-.-) (Elongin-A-binding protein 1) (EloA-BP1) (Transcription elongation factor B polypeptide 3-binding protein 1)REXO1 ELOABP1 KIAA1138 TCEB3BP1Q8N1G13
RNA-binding motif protein, X-linked-like-2 (Testis-specific heterogeneous nuclear ribonucleoprotein G-T) (hnRNP G-T)RBMXL2 HNRNPGTO755263
RNA-binding protein 28 (RNA-binding motif protein 28)RBM28Q9NW133
RNA-binding protein 5 (Protein G15) (Putative tumor suppressor LUCA15) (RNA-binding motif protein 5) (Renal carcinoma antigen NY-REN-9)RBM5 H37 LUCA15P527563
RNA-binding protein Nova-2 (Astrocytic NOVA1-like RNA-binding protein) (Neuro-oncological ventral antigen 2)NOVA2 ANOVA NOVA3Q9UNW93
RNA/RNP complex-1-interacting phosphatase (EC 3.1.3.-) (Dual specificity protein phosphatase 11) (Phosphatase that interacts with RNA/RNP complex 1)DUSP11 PIR1O753193
Ropporin-1B (Rhophilin-associated protein 1B)ROPN1BQ9BZX43
RQCD1 proteinRQCD1D5MQE13
RUN and FYVE domain-containing protein 2 (Rab4-interacting protein related)RUFY2 KIAA1537 RABIP4RQ8WXA33
RUN and FYVE domain-containing protein 4RUFY4Q6ZNE93
RUN and SH3 domain-containing protein 1 (New molecule containing SH3 at the carboxy-terminus) (Nesca)RUSC1 NESCAQ9BVN23
RWD domain-containing protein 1 (DRG family-regulatory protein 2)RWDD1 DFRP2 CGI-24 PTD013Q9H4463
S phase cyclin A-associated protein in the endoplasmic reticulum (S phase cyclin A-associated protein in the ER) (Zinc finger protein 291)SCAPER KIAA1454 ZNF291 MSTP063Q9BY123
SAFB-like transcription modulator (Modulator of estrogen-induced transcription)SLTM METQ9NWH93
SAGA-associated factor 29 homolog (Coiled-coil domain-containing protein 101)CCDC101 SGF29Q96ES73
SAR1 gene homolog A (S. cerevisiae), isoform CRA_a (Small GTP-binding protein)SAR1A hCG_1787550Q5SQT93
Scavenger receptor class A member 5 (Scavenger receptor hlg)SCARA5 UNQ2938/PRO28700Q6ZMJ23
Scavenger receptor cysteine-rich type 1 protein M160 (CD163 antigen-like 1) (CD antigen CD163b)CD163L1 CD163B M160 UNQ6434/PRO23202Q9NR163
Secretion-regulating guanine nucleotide exchange factor (Deafness locus-associated putative guanine nucleotide exchange factor) (DelGEF) (Guanine nucleotide exchange factor-related protein)SERGEF DELGEF GNEFRQ9UGK83
Sel1 repeat-containing protein 1 (Beta-lactamase hcp-like protein)SELRC1 C1orf163Q96BR53
Selenoprotein O (SelO)SELOQ9BVL43
Selenoprotein V (SelV)SELVP597973
Semaphorin-3ESEMA3E KIAA0331 SEMAHO150413
Sentrin-specific protease 2 (EC 3.4.22.68) (Axam2) (SMT3-specific isopeptidase 2) (Smt3ip2) (Sentrin/SUMO-specific protease SENP2)SENP2 KIAA1331Q9HC623
Septin-4 (Apoptosis-related protein in the TGF-beta signaling pathway) (ARTS) (Bradeion beta) (Brain protein H5) (CE5B3 beta) (Cell division control-related protein 2) (hCDCREL-2) (Cerebral protein 7) (Peanut-like protein 2)SEPT4 ARTS PNUTL2 SEP4 hucep-7O432363
Serine dehydratase-like (L-serine deaminase) (L-serine dehydratase/L-threonine deaminase) (L-threonine dehydratase) (TDH) (EC 4.3.1.19) (Serine dehydratase 2) (SDH 2) (EC 4.3.1.17)SDSLQ96GA73
Serine protease inhibitor Kazal-type 4 (Peptide PEC-60 homolog)SPINK4O605753
Serine-rich coiled-coil domain-containing protein 2 (Coiled-coil serine-rich protein 2) (Protein GCAP14 homolog)CCSER2 FAM190B KIAA1128 NPD012Q9H7U13
Serine/arginine-rich splicing factor 8 (Pre-mRNA-splicing factor SRP46) (Splicing factor SRp46) (Splicing factor, arginine/serine-rich 2B)SRSF8 SFRS2B SRP46Q9BRL63
Serine/threonine-protein kinase 16 (EC 2.7.11.1) (Myristoylated and palmitoylated serine/threonine-protein kinase) (MPSK) (Protein kinase PKL12) (TGF-beta-stimulated factor 1) (TSF-1) (Tyrosine-protein kinase STK16) (EC 2.7.10.2) (hPSK)STK16 MPSK1 PKL12 TSF1O757163
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