EVpedia provide top 100+ EV markers, selected according to their identification number.
Based on EV proteomes, we defined the identification number of protein A as the number of datasets which contain protein A.
Therefore, proteins with higher identification numbers were more conserved.

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Protein name Gene symbol UniProt accession Identification number
Stress-associated endoplasmic reticulum protein 2 (Ribosome-associated membrane protein RAMP4-2)SERP2 C13orf21Q8N6R13
Stromal cell-derived factor 1 (SDF-1) (hSDF-1) (C-X-C motif chemokine 12) (Intercrine reduced in hepatomas) (IRH) (hIRH) (Pre-B cell growth-stimulating factor) (PBSF) [Cleaved into: SDF-1-beta(3-72); SDF-1-alpha(3-67)]CXCL12 SDF1 SDF1A SDF1BP480613
Stromal cell-derived factor 2-like protein 1 (SDF2-like protein 1) (PWP1-interacting protein 8)SDF2L1 UNQ1941/PRO4424Q9HCN83
Stromal membrane-associated protein 2 (Stromal membrane-associated protein 1-like)SMAP2 SMAP1LQ8WU793
Structural maintenance of chromosomes protein 2 (SMC protein 2) (SMC-2) (Chromosome-associated protein E) (hCAP-E) (XCAP-E homolog)SMC2 CAPE SMC2L1 PRO0324O953473
Succinyl-CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial (EC 6.2.1.4) (EC 6.2.1.5) (Succinyl-CoA synthetase subunit alpha) (SCS-alpha)SUCLG1P535973
Sugar phosphate exchanger 3 (Solute carrier family 37 member 3)SLC37A3 SPX3Q8NCC53
Sugar transporter SWEET1 (HsSWEET1) (RAG1-activating protein 1) (Solute carrier family 50 member 1) (Stromal cell protein)SLC50A1 RAG1AP1 SCPQ9BRV33
SUN domain-containing ossification factor (Membrane protein CH1) (Protein osteopotentia homolog) (SUN-like protein 1)SUCO C1orf9 CH1 OPT SLP1Q9UBS93
SUN domain-containing protein 2 (Protein unc-84 homolog B) (Rab5-interacting protein) (Rab5IP) (Sad1/unc-84 protein-like 2)SUN2 FRIGG KIAA0668 RAB5IP UNC84BQ9UH993
Suppressor of cytokine signaling 4 (SOCS-4) (Suppressor of cytokine signaling 7) (SOCS-7)SOCS4 SOCS7Q8WXH53
Suppressor of G2 allele of SKP1 homolog (Protein 40-6-3) (Sgt1)SUGT1Q9Y2Z03
Suppressor of IKBKE 1 (Suppressor of IKK-epsilon)SIKE1 SIKEQ9BRV83
Suppressor of SWI4 1 homolog (Ssf-1) (Brix domain-containing protein 3) (Peter Pan homolog)PPAN BXDC3 SSF1Q9NQ553
Suppressor of tumorigenicity 20 protein (Human cervical cancer suppressor gene 1 protein) (HCCS-1)ST20 HCCS1Q9HBF53
Suppressor of tumorigenicity 7 protein (Protein FAM4A1) (Protein HELG)ST7 FAM4A1 HELG RAY1Q9NRC13
Surfactant-associated protein 2 (Surfactant-associated protein G)SFTA2 SFTPG UNQ541/PRO1098Q6UW103
Sushi domain-containing protein 2SUSD2Q9UGT43
Synaptogyrin-4SYNGR4O954733
Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol 1,4,5-trisphosphate 5-phosphatase 1)SYNJ1 KIAA0910O434263
Synaptonemal complex protein SC65 (Leprecan-like protein 4) (Nucleolar autoantigen No55)LEPREL4 NOL55 SC65Q927913
SynaptopodinSYNPO KIAA1029Q8N3V73
Synaptotagmin-17 (Protein B/K) (Synaptotagmin XVII) (SytXVII)SYT17Q9BSW73
Synaptotagmin-5 (Synaptotagmin V) (SytV)SYT5O004453
Synaptotagmin-like protein 1 (Exophilin-7) (Protein JFC1)SYTL1 SLP1 SB146Q8IYJ33
Synaptotagmin-like protein 5SYTL5 SLP5Q8TDW53
Syndecan-4 (SYND4) (Amphiglycan) (Ryudocan core protein)SDC4P314313
Synembryn-A (Protein Ric-8A)RIC8AQ9NPQ83
Syntaxin-3STX3 STX3AQ132773
T-box transcription factor TBX6 (T-box protein 6)TBX6O959473
T-cell immunomodulatory protein (Protein TIP) (Integrin-alpha FG-GAP repeat-containing protein 1)ITFG1 TIP CDA08Q8TB963
T-cell leukemia homeobox protein 2 (Homeobox protein Hox-11L1) (Neural crest homeobox protein)TLX2 HOX11L1 NCXO437633
TACI (Tumor necrosis factor receptor superfamily, member 13B) (Tumor necrosis factor receptor superfamily, member 13B, isoform CRA_a)TACI TNFRSF13B hCG_28297Q4ACX13
TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa (TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa, isoform CRA_b) (cDNA, FLJ94920, Homo sapiens TAF15 RNA polymerase II, TATA box binding protein(TBP)-associated factor, 68kDa (TAF15), transcript variant 1, mRNA)TAF15 hCG_1992163Q86X943
Talin-2TLN2 KIAA0320Q9Y4G63
TANK-binding kinase 1-binding protein 1 (TBK1-binding protein 1)TBKBP1 KIAA0775A7MCY63
Tankyrase-1 (TANK1) (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 5) (ARTD5) (Poly [ADP-ribose] polymerase 5A) (TNKS-1) (TRF1-interacting ankyrin-related ADP-ribose polymerase) (Tankyrase I)TNKS PARP5A PARPL TIN1 TINF1 TNKS1O952713
Tapasin (TPN) (TPSN) (NGS-17) (TAP-associated protein) (TAP-binding protein)TAPBP NGS17 TAPAO155333
Target of EGR1 protein 1TOE1Q96GM83
Tartrate-resistant acid phosphatase type 5 (TR-AP) (EC 3.1.3.2) (Tartrate-resistant acid ATPase) (TrATPase) (Type 5 acid phosphatase)ACP5P136863
TBC1 domain family member 1TBC1D1 KIAA1108Q86TI03
TBC1 domain family member 15 (GTPase-activating protein RAB7) (GAP for RAB7) (Rab7-GAP)TBC1D15Q8TC073
TBC1 domain family member 28TBC1D28Q2M2D73
TBC1 domain family member 3FTBC1D3F TBC1D3EA6NER03
TBC1 domain family member 3HTBC1D3HP0C7X13
TBCC domain-containing protein 1TBCCD1Q9NVR73
Tectonin beta-propeller repeat-containing protein 1TECPR1 KIAA1358Q7Z6L13
Tektin-4TEKT4Q8WW243
Telomerase reverse transcriptase (EC 2.7.7.49) (HEST2) (Telomerase catalytic subunit) (Telomerase-associated protein 2) (TP2)TERT EST2 TCS1 TRTO147463
Telomere-associated protein RIF1 (Rap1-interacting factor 1 homolog)RIF1Q5UIP03
Telomeric repeat-binding factor 2 (TTAGGG repeat-binding factor 2) (Telomeric DNA-binding protein)TERF2 TRBF2 TRF2Q155543
Terminal uridylyltransferase 7 (TUTase 7) (EC 2.7.7.52) (Zinc finger CCHC domain-containing protein 6)ZCCHC6 HS2 KIAA1711 TUT7Q5VYS83
Testis anion transporter 1 (Anion exchange transporter) (Solute carrier family 26 member 8)SLC26A8 TAT1Q96RN13
Testis-expressed sequence 2 protein (Transmembrane protein 96)TEX2 KIAA1738 TMEM96Q8IWB93
Testis-expressed sequence 30 proteinTEX30 C13orf27Q5JUR73
Tetraspanin-10 (Tspan-10) (Oculospanin)TSPAN10 OCSPQ9H1Z93
Tetraspanin-11 (Tspan-11)TSPAN11A1L1573
Tetraspanin-9 (Tspan-9) (Tetraspan NET-5)TSPAN9 NET5O759543
Tetratricopeptide repeat protein 19, mitochondrial (TPR repeat protein 19)TTC19Q6DKK23
Tetratricopeptide repeat protein 24 (TPR repeat protein 24)TTC24A2A3L63
Tetratricopeptide repeat protein 27 (TPR repeat protein 27)TTC27Q6P3X33
TGFB1-induced anti-apoptotic factor 1 (12 kDa TGF-beta-1-induced antiapoptotic factor)TIAF1O954113
Thimet oligopeptidase (EC 3.4.24.15) (Endopeptidase 24.15) (MP78)THOP1P528883
Thiosulfate sulfurtransferase/rhodanese-like domain-containing protein 1TSTD1 KATQ8NFU33
THO complex subunit 4ALYREFE9PB613
Threonine synthase-like 2 (TSH2) (EC 4.2.3.-) (Secreted osteoclastogenic factor of activated T-cells) (SOFAT)THNSL2Q86YJ63
Thrombospondin-3THBS3 TSP3P497463
Thymidine kinase 2, mitochondrial (EC 2.7.1.21) (Mt-TK)TK2O001423
Tigger transposable element-derived protein 5TIGD5Q53EQ63
Tight junction protein ZO-2 (Tight junction protein 2) (Zona occludens protein 2) (Zonula occludens protein 2)TJP2 X104 ZO2Q9UDY23
Tight junction-associated protein 1 (Protein incorporated later into tight junctions) (Tight junction protein 4)TJAP1 PILT TJP4Q5JTD03
TM2 domain-containing protein 3 (Beta-amyloid-binding protein-like protein 2) (BBP-like protein 2)TM2D3 BLP2Q9BRN93
TNS1 proteinTNS1Q86VB03
TOM1-like protein 1 (Src-activating and signaling molecule protein) (Target of Myb-like protein 1)TOM1L1 SRCASMO756743
TraB domain-containing protein (Protein TTG2)TRABD TTG2 PP2447Q9H4I33
TRAF-type zinc finger domain-containing protein 1 (Protein FLN29)TRAFD1 FLN29O145453
Trafficking protein particle complex subunit 12 (Tetratricopeptide repeat protein 15) (TPR repeat protein 15) (TTC-15)TRAPPC12 TTC15 CGI-87Q8WVT33
Trafficking protein particle complex subunit 4 (Hematopoietic stem/progenitor cell protein 172) (Synbindin) (TRS23 homolog)TRAPPC4 SBDN CGI-104 HSPC172 PTD009Q9Y2963
Trafficking protein particle complex subunit 6A (TRAPP complex subunit 6A)TRAPPC6A HSPC289O758653
Trans-2-enoyl-CoA reductase, mitochondrial (EC 1.3.1.38) (Nuclear receptor-binding factor 1) (HsNrbf-1) (NRBF-1)MECR NBRF1 CGI-63Q9BV793
Transcription elongation factor A N-terminal and central domain-containing protein 2TCEANC2 C1orf83Q96MN53
Transcription elongation factor A protein-like 1 (TCEA-like protein 1) (Nuclear phosphoprotein p21/SIIR) (Transcription elongation factor S-II protein-like 1)TCEAL1 SIIRQ151703
Transcription elongation regulator 1-like proteinTCERG1LQ5VWI13
Transcription factor 20 (TCF-20) (Nuclear factor SPBP) (Protein AR1) (Stromelysin-1 PDGF-responsive element-binding protein) (SPRE-binding protein)TCF20 KIAA0292 SPBPQ9UGU03
Transcription factor 7-like 1 (HMG box transcription factor 3) (TCF-3)TCF7L1 TCF3Q9HCS43
Transcription factor AP-2-beta (AP2-beta) (Activating enhancer-binding protein 2-beta)TFAP2BQ924813
Transcription factor AP-2-epsilon (AP2-epsilon) (Activating enhancer-binding protein 2-epsilon)TFAP2EQ6VUC03
Transcription factor COE3 (Early B-cell factor 3) (EBF-3) (Olf-1/EBF-like 2) (O/E-2) (OE-2)EBF3 COE3Q9H4W63
Transcription factor E2F1 (E2F-1) (PBR3) (Retinoblastoma-associated protein 1) (RBAP-1) (Retinoblastoma-binding protein 3) (RBBP-3) (pRB-binding protein E2F-1)E2F1 RBBP3Q010943
Transcription factor E2F4 (E2F-4)E2F4Q162543
Transcription factor GATA-5 (GATA-binding factor 5)GATA5Q9BWX53
Transcription factor HES-4HES4E9PB283
Transcription factor jun-BJUNBP172753
Transcription factor LBX1 (Ladybird homeobox protein homolog 1)LBX1 LBX1HP529543
Transcription factor MafB (Maf-B) (V-maf musculoaponeurotic fibrosarcoma oncogene homolog B)MAFB KRMLQ9Y5Q33
Transcription factor PU.1 (31 kDa-transforming protein)SPI1P179473
Transcription factor RFX3 (Regulatory factor X 3)RFX3P483803
Transcription factor SOX-3SOX3P412253
Transcription factor SOX-5SOX5P357113
Transcription factor Sp3 (SPR-2)SP3Q024473
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