EVpedia provide top 100+ EV markers, selected according to their identification number.
Based on EV proteomes, we defined the identification number of protein A as the number of datasets which contain protein A.
Therefore, proteins with higher identification numbers were more conserved.

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Protein name Gene symbol UniProt accession Identification number
2'-5'-oligoadenylate synthase-like protein (2'-5'-OAS-related protein) (2'-5'-OAS-RP) (59 kDa 2'-5'-oligoadenylate synthase-like protein) (Thyroid receptor-interacting protein 14) (TR-interacting protein 14) (TRIP-14) (p59 OASL) (p59OASL)OASL TRIP14Q156462
2-5A-dependent ribonuclease (2-5A-dependent RNase) (EC 3.1.26.-) (Ribonuclease 4) (Ribonuclease L) (RNase L)RNASEL RNS4Q058232
2-amino-3-carboxymuconate-6-semialdehyde decarboxylase (EC 4.1.1.45) (Picolinate carboxylase)ACMSDQ8TDX52
2-hydroxyacyl-CoA lyase 1 (EC 4.1.-.-) (2-hydroxyphytanoyl-CoA lyase) (2-HPCL) (Phytanoyl-CoA 2-hydroxylase 2)HACL1 HPCL HPCL2 PHYH2 HSPC279Q9UJ832
2-oxoglutarate dehydrogenase-like, mitochondrial (EC 1.2.4.-) (2-oxoglutarate dehydrogenase complex component E1-like) (OGDC-E1-like) (Alpha-ketoglutarate dehydrogenase-like)OGDHL KIAA1290Q9ULD02
28 kDa heat- and acid-stable phosphoprotein (PDGF-associated protein) (PAP) (PDGFA-associated protein 1) (PAP1)PDAP1 HASPP28Q134422
28S ribosomal protein S5, mitochondrial (MRP-S5) (S5mt)MRPS5P826752
3'(2'),5'-bisphosphate nucleotidase 1 (EC 3.1.3.7) (Bisphosphate 3'-nucleotidase 1) (PAP-inositol 1,4-phosphatase) (PIP)BPNT1O958612
3-hydroxy-3-methylglutaryl-Coenzyme A synthase 1 (Soluble)HMGCS1Q5XJ042
3-oxo-5-alpha-steroid 4-dehydrogenase 2 (EC 1.3.1.22) (5 alpha-SR2) (SR type 2) (Steroid 5-alpha-reductase 2) (S5AR 2) (Type II 5-alpha reductase)SRD5A2P312132
39S ribosomal protein L16, mitochondrial (L16mt) (MRP-L16)MRPL16 PNAS-111Q9NX202
39S ribosomal protein L2, mitochondrial (L2mt) (MRP-L2)MRPL2 CGI-22Q5T6532
39S ribosomal protein L30, mitochondrial (L30mt) (MRP-L30) (39S ribosomal protein L28, mitochondrial) (L28mt) (MRP-L28)MRPL30 MRPL28 RPML28 HSPC249Q8TCC32
39S ribosomal protein L32, mitochondrial (L32mt) (MRP-L32)MRPL32 HSPC283Q9BYC82
39S ribosomal protein L39, mitochondrial (L39mt) (MRP-L39) (39S ribosomal protein L5, mitochondrial) (L5mt) (MRP-L5)MRPL39 C21orf92 MRPL5 RPML5 MSTP003 PRED22Q9NYK52
4-hydroxyphenylpyruvate dioxygenase (EC 1.13.11.27) (4-hydroxyphenylpyruvic acid oxidase) (4HPPD) (HPD) (HPPDase)HPD PPDP327542
40S ribosomal protein S4, Y isoform 2RPS4Y2 RPS4Y2PQ8TD472
5'(3')-deoxyribonucleotidase, mitochondrial (5',3'-nucleotidase, mitochondrial) (EC 3.1.3.-) (Deoxy-5'-nucleotidase 2) (dNT-2)NT5M DNT2Q9NPB12
5'-AMP-activated protein kinase catalytic subunit alpha-1 (AMPK subunit alpha-1) (EC 2.7.11.1) (Acetyl-CoA carboxylase kinase) (ACACA kinase) (EC 2.7.11.27) (Hydroxymethylglutaryl-CoA reductase kinase) (HMGCR kinase) (EC 2.7.11.31) (Tau-protein kinase PRKAA1) (EC 2.7.11.26)PRKAA1 AMPK1Q131312
5'-AMP-activated protein kinase subunit beta-2 (AMPK subunit beta-2)PRKAB2O437412
5'-nucleotidase domain-containing protein 3 (EC 3.1.3.-) (GRP94-neighboring nucleotidase)NT5DC3 GNN TU12B1-TYQ86UY82
5-azacytidine-induced protein 2 (NF-kappa-B-activating kinase-associated protein 1) (Nak-associated protein 1) (TILP)AZI2 NAP1Q9H6S12
5-hydroxytryptamine receptor 7 (5-HT-7) (5-HT7) (5-HT-X) (Serotonin receptor 7)HTR7P349692
55 kDa erythrocyte membrane protein (p55) (Membrane protein, palmitoylated 1)MPP1 DXS552E EMP55Q000132
60S ribosomal protein L10-likeRPL10LQ96L212
60S ribosomal protein L15RPL15 EC45 TCBAP0781P613132
60S ribosomal protein L35a (Cell growth-inhibiting gene 33 protein)RPL35A GIG33P180772
60S ribosomal protein L36aRPL36AJ3KQN42
A disintegrin and metalloproteinase with thrombospondin motifs 12 (ADAM-TS 12) (ADAM-TS12) (ADAMTS-12) (EC 3.4.24.-)ADAMTS12 UNQ1918/PRO4389P583972
A disintegrin and metalloproteinase with thrombospondin motifs 16 (ADAM-TS 16) (ADAM-TS16) (ADAMTS-16) (EC 3.4.24.-)ADAMTS16 KIAA2029Q8TE572
A disintegrin and metalloproteinase with thrombospondin motifs 17 (ADAM-TS 17) (ADAM-TS17) (ADAMTS-17) (EC 3.4.24.-)ADAMTS17Q8TE562
A disintegrin and metalloproteinase with thrombospondin motifs 5 (ADAM-TS 5) (ADAM-TS5) (ADAMTS-5) (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 11) (ADAM-TS 11) (ADAMTS-11) (ADMP-2) (Aggrecanase-2)ADAMTS5 ADAMTS11 ADMP2Q9UNA02
A-kinase anchor protein 1, mitochondrial (A-kinase anchor protein 149 kDa) (AKAP 149) (Dual specificity A-kinase-anchoring protein 1) (D-AKAP-1) (Protein kinase A-anchoring protein 1) (PRKA1) (Spermatid A-kinase anchor protein 84) (S-AKAP84)AKAP1 AKAP149 PRKA1Q926672
AarF domain containing kinase 2 (AarF domain containing kinase 2, isoform CRA_a)ADCK2 hCG_40135A4D1T62
Abhydrolase domain-containing protein 16B (EC 3.-.-.-)ABHD16B C20orf135Q9H3Z72
Abhydrolase domain-containing protein 2 (EC 3.1.1.-) (Lung alpha/beta hydrolase 2) (Protein PHPS1-2)ABHD2 LABH2P089102
ABI gene family member 3 (New molecule including SH3) (Nesh)ABI3 NESHQ9P2A42
Absent in melanoma 1 protein (Beta/gamma crystallin domain-containing protein 1)AIM1 CRYBG1Q9Y4K12
Absent in melanoma 1-like protein (Beta/gamma crystallin domain-containing protein 2)AIM1L CRYBG2Q8N1P72
Acetyl-CoA carboxylase 2 (EC 6.4.1.2) (ACC-beta) [Includes: Biotin carboxylase (EC 6.3.4.14)]ACACB ACC2 ACCBO007632
Acetylcholine receptor subunit deltaCHRND ACHRDQ070012
Acid sphingomyelinase-like phosphodiesterase 3a (ASM-like phosphodiesterase 3a) (EC 3.1.4.-)SMPDL3A ASML3AQ924842
Acid trehalase-like protein 1 (EC 3.2.1.-)ATHL1Q32M882
Acid-sensing ion channel 2 (ASIC2) (Amiloride-sensitive brain sodium channel) (Amiloride-sensitive cation channel 1, neuronal) (Amiloride-sensitive cation channel neuronal 1) (Brain sodium channel 1) (BNC1) (BNaC1) (Mammalian degenerin homolog)ASIC2 ACCN ACCN1 BNAC1 MDEGQ165152
ACSS2 protein (Fragment)ACSS2Q6DKJ32
Actin related protein 2/3 complex, subunit 1B, 41kDa (Actin related protein 2/3 complex, subunit 1B, 41kDa, isoform CRA_a) (cDNA, FLJ95695, Homo sapiens actin related protein 2/3 complex, subunit 1B, 41kDa(ARPC1B), mRNA)ARPC1B hCG_19475 tcag7.662A4D2752
Actin, alpha 2, smooth muscle, aorta (Actin, alpha 2, smooth muscle, aorta, isoform CRA_a)ACTA2 hCG_22984D2JYH42
Actin, alpha cardiac muscle 1 (Alpha-cardiac actin)ACTC1 ACTCP680322
Actin, alpha skeletal muscle (Alpha-actin-1)ACTA1 ACTAP681332
Actin-binding LIM protein 2 (abLIM-2) (Actin-binding LIM protein family member 2)ABLIM2 KIAA1808Q6H8Q12
Actin-like protein 9ACTL9 ACTL7C HSD21Q8TC942
Active regulator of SIRT1 (40S ribosomal protein S19-binding protein 1) (RPS19-binding protein 1) (S19BP)RPS19BP1 AROSQ86WX32
Acyl-CoA synthetase family member 2, mitochondrial (EC 6.2.1.-)ACSF2 UNQ493/PRO1009Q96CM82
Acyl-CoA synthetase family member 3, mitochondrial (EC 6.2.1.-)ACSF3 PSEC0197Q4G1762
Acyl-CoA-binding domain-containing protein 4ACBD4 HMFT0700Q8NC062
Acyl-coenzyme A synthetase ACSM2A, mitochondrial (EC 6.2.1.2) (Acyl-CoA synthetase medium-chain family member 2A) (Butyrate--CoA ligase 2A) (Butyryl-coenzyme A synthetase 2A) (Middle-chain acyl-CoA synthetase 2A)ACSM2A ACSM2 MACS2Q08AH32
Acyl-coenzyme A synthetase ACSM2B, mitochondrial (EC 6.2.1.2) (Acyl-CoA synthetase medium-chain family member 2B) (Butyrate--CoA ligase 2B) (Butyryl-coenzyme A synthetase 2B) (Middle-chain acyl-CoA synthetase 2B) (Xenobiotic/medium-chain fatty acid-CoA ligase HXM-A)ACSM2B ACSM2 HYST1046Q68CK62
Acyl-coenzyme A thioesterase 1 (Acyl-CoA thioesterase 1) (EC 3.1.2.2) (CTE-I) (CTE-Ib) (Inducible cytosolic acyl-coenzyme A thioester hydrolase) (Long chain acyl-CoA thioester hydrolase) (Long chain acyl-CoA hydrolase)ACOT1 CTE1Q86TX22
Acyl-coenzyme A thioesterase 2, mitochondrial (Acyl-CoA thioesterase 2) (EC 3.1.2.2) (Acyl-coenzyme A thioester hydrolase 2a) (CTE-Ia) (Long-chain acyl-CoA thioesterase 2) (ZAP128)ACOT2 PTE2 PTE2AP497532
Acyl-coenzyme A thioesterase 8 (Acyl-CoA thioesterase 8) (EC 3.1.2.27) (Choloyl-coenzyme A thioesterase) (HIV-Nef-associated acyl-CoA thioesterase) (PTE-2) (Peroxisomal acyl-coenzyme A thioester hydrolase 1) (PTE-1) (Peroxisomal long-chain acyl-CoA thioesterase 1) (Thioesterase II) (hACTE-III) (hACTEIII) (hTE)ACOT8 ACTEIII PTE1 PTE2O147342
Acyl-coenzyme A thioesterase 9, mitochondrial (Acyl-CoA thioesterase 9) (EC 3.1.2.-) (Acyl-CoA thioester hydrolase 9)ACOT9 CGI-16Q9Y3052
Acylglycerol kinase, mitochondrial (hAGK) (EC 2.7.1.107) (EC 2.7.1.94) (Multiple substrate lipid kinase) (HsMuLK) (MuLK) (Multi-substrate lipid kinase)AGK MULKQ53H122
Adducin 3 (Gamma), isoform CRA_a (cDNA FLJ77558, highly similar to Homo sapiens adducin 3 (gamma) (ADD3), transcript variant 1, mRNA)ADD3 hCG_1789399Q5VU082
Adenylate cyclase type 5 (EC 4.6.1.1) (ATP pyrophosphate-lyase 5) (Adenylate cyclase type V) (Adenylyl cyclase 5)ADCY5O956222
Adenylate kinase 9 (AK 9) (EC 2.7.4.4) (EC 2.7.4.6) (Adenylate kinase domain-containing protein 1) (Adenylate kinase domain-containing protein 2)AK9 AKD1 AKD2 C6orf199 C6orf224Q5TCS82
Adenylate kinase isoenzyme 1 (AK 1) (EC 2.7.4.3) (EC 2.7.4.6) (ATP-AMP transphosphorylase 1) (ATP:AMP phosphotransferase) (Adenylate monophosphate kinase) (Myokinase)AK1P005682
Adenylate kinase isoenzyme 5 (AK 5) (EC 2.7.4.3) (EC 2.7.4.6) (ATP-AMP transphosphorylase 5)AK5Q9Y6K82
Adenylosuccinate synthetase isozyme 2 (AMPSase 2) (AdSS 2) (EC 6.3.4.4) (Adenylosuccinate synthetase, acidic isozyme) (Adenylosuccinate synthetase, liver isozyme) (L-type adenylosuccinate synthetase) (IMP--aspartate ligase 2)ADSS ADSS2P305202
Adenylyl cyclase-associated proteinDKFZp686D0714Q5JPJ82
AdipogeninADIGQ0VDE82
ADP-ribosylation factor-related protein 1 (ARF-related protein 1) (ARP)ARFRP1 ARP1Q137952
Adrenergic, alpha-1D-, receptorADRA1D hCG_1646223B0ZBE02
Adrenergic, alpha-2C-, receptor (Putative uncharacterized protein ADRA2C)ADRA2CQ4W5942
Adrenocorticotropic hormone receptor (ACTH receptor) (ACTH-R) (Adrenocorticotropin receptor) (Melanocortin receptor 2) (MC2-R)MC2R ACTHRQ017182
Aladin (Adracalin)AAAS ADRACALA GL003Q9NRG92
Alanine--glyoxylate aminotransferase 2, mitochondrial (AGT 2) (EC 2.6.1.44) ((R)-3-amino-2-methylpropionate--pyruvate transaminase) (EC 2.6.1.40) (Beta-ALAAT II) (Beta-alanine-pyruvate aminotransferase) (D-AIBAT)AGXT2 AGT2Q9BYV12
Alcohol dehydrogenase 1B (EC 1.1.1.1) (Alcohol dehydrogenase subunit beta)ADH1B ADH2P003252
Aldehyde dehydrogenase 5 family, member A1 (Succinate-semialdehyde dehydrogenase), isoform CRA_b (Succinic semialdehyde dehydrogenase) (EC 1.2.1.24)ALDH5A1 hCG_37509Q546H92
Aldo-keto reductase family 1 member C4 (EC 1.1.1.-) (3-alpha-HSD1) (3-alpha-hydroxysteroid dehydrogenase type I) (EC 1.1.1.357) (Chlordecone reductase) (CDR) (EC 1.1.1.225) (Dihydrodiol dehydrogenase 4) (DD-4) (DD4) (HAKRA)AKR1C4 CHDRP175162
Alkaline ceramidase 3 (AlkCDase 3) (Alkaline CDase 3) (EC 3.5.1.-) (Alkaline dihydroceramidase SB89) (Alkaline phytoceramidase) (aPHC)ACER3 APHC PHCAQ9NUN72
Alpha-(1,3)-fucosyltransferase 5 (EC 2.4.1.65) (Fucosyltransferase 5) (Fucosyltransferase V) (Fuc-TV) (FucT-V) (Galactoside 3-L-fucosyltransferase)FUT5Q111282
Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase A (EC 2.4.1.145) (N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase IVa) (GlcNAc-T IVa) (GnT-IVa) (N-acetylglucosaminyltransferase IVa) (UDP-N-acetylglucosamine: alpha-1,3-D-mannoside beta-1,4-N-acetylglucosaminyltransferase IVa) [Cleaved into: Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase A soluble form]MGAT4AQ9UM212
Alpha-1,3/1,6-mannosyltransferase ALG2 (EC 2.4.1.132) (EC 2.4.1.257) (Asparagine-linked glycosylation protein 2 homolog) (GDP-Man:Man(1)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase) (GDP-Man:Man(1)GlcNAc(2)-PP-dolichol mannosyltransferase) (GDP-Man:Man(2)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase)ALG2 UNQ666/PRO1298Q9H5532
Alpha-1-antichymotrypsin (ACT) (Cell growth-inhibiting gene 24/25 protein) (Serpin A3) [Cleaved into: Alpha-1-antichymotrypsin His-Pro-less]SERPINA3 AACT GIG24 GIG25P010112
Alpha-1B-glycoprotein (Alpha-1-B glycoprotein)A1BGP042172
Alpha-2-macroglobulin (Alpha-2-M) (C3 and PZP-like alpha-2-macroglobulin domain-containing protein 5)A2M CPAMD5 FWP007P010232
Alpha-2A adrenergic receptor (Alpha-2 adrenergic receptor subtype C10) (Alpha-2A adrenoreceptor) (Alpha-2A adrenoceptor) (Alpha-2AAR)ADRA2A ADRA2R ADRARP089132
Alpha-mannosidase 2x (EC 3.2.1.114) (Alpha-mannosidase IIx) (Man IIx) (Mannosidase alpha class 2A member 2) (Mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase)MAN2A2 MANA2XP496412
Alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3-N-acetyl-galactosaminide alpha-2,6-sialyltransferase (EC 2.4.99.7) (NeuAc-alpha-2,3-Gal-beta-1,3-GalNAc-alpha-2,6-sialyltransferase) (ST6GalNAc IV) (ST6GalNAcIV) (Sialyltransferase 3C) (SIAT3-C) (Sialyltransferase 7D) (SIAT7-D)ST6GALNAC4 SIAT3C SIAT7DQ9H4F12
Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 (EC 2.4.99.-) (GalNAc alpha-2,6-sialyltransferase II) (ST6GalNAc II) (ST6GalNAcII) (SThM) (Sialyltransferase 7B) (SIAT7-B)ST6GALNAC2 SIAT7B SIATL1 STHMQ9UJ372
Alpha/beta hydrolase domain-containing protein 17C (EC 3.-.-.-)ABHD17C FAM108C1Q6PCB62
Amiloride-sensitive amine oxidase [copper-containing] (DAO) (Diamine oxidase) (EC 1.4.3.22) (Amiloride-binding protein 1) (Amine oxidase copper domain-containing protein 1) (Histaminase) (Kidney amine oxidase) (KAO)AOC1 ABP1 DAO1P198012
Amiloride-sensitive sodium channel subunit beta (Beta-NaCH) (Epithelial Na(+) channel subunit beta) (Beta-ENaC) (ENaCB) (Nonvoltage-gated sodium channel 1 subunit beta) (SCNEB)SCNN1BP511682
Amiloride-sensitive sodium channel subunit delta (Delta-NaCH) (Epithelial Na(+) channel subunit delta) (Delta-ENaC) (ENaCD) (Nonvoltage-gated sodium channel 1 subunit delta) (SCNED)SCNN1D DNACHP511722
Amiloride-sensitive sodium channel subunit gamma (Epithelial Na(+) channel subunit gamma) (ENaCG) (Gamma-ENaC) (Gamma-NaCH) (Nonvoltage-gated sodium channel 1 subunit gamma) (SCNEG)SCNN1GP511702
AMP deaminase 2 (EC 3.5.4.6) (AMP deaminase isoform L)AMPD2Q014332
Amphoterin-induced protein 2 (AMIGO-2) (Alivin-1) (Differentially expressed in gastric adenocarcinomas) (DEGA)AMIGO2 ALI1Q86SJ22
AMSH-like protease (AMSH-LP) (EC 3.4.19.-) (STAM-binding protein-like 1)STAMBPL1 AMSHLP KIAA1373Q96FJ02
Amyloid beta A4 precursor protein-binding family A member 1 (Adapter protein X11alpha) (Neuron-specific X11 protein) (Neuronal Munc18-1-interacting protein 1) (Mint-1)APBA1 MINT1 X11Q024102
Amyloid beta A4 precursor protein-binding family A member 2 (Adapter protein X11beta) (Neuron-specific X11L protein) (Neuronal Munc18-1-interacting protein 2) (Mint-2)APBA2 MINT2 X11LQ997672
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