EVpedia provide top 100+ EV markers, selected according to their identification number.
Based on EV proteomes, we defined the identification number of protein A as the number of datasets which contain protein A.
Therefore, proteins with higher identification numbers were more conserved.

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Protein name Gene symbol UniProt accession Identification number
Intelectin-2 (Endothelial lectin HL-2)ITLN2 UNQ2789/PRO7179Q8WWU72
Interferon regulatory factor 2-binding protein 2 (IRF-2-binding protein 2) (IRF-2BP2)IRF2BP2Q7Z5L92
Interferon regulatory factor 2-binding protein-like (Enhanced at puberty protein 1)IRF2BPL C14orf4 EAP1 KIAA1865 My039Q9H1B72
Interferon regulatory factor 4 (IRF-4) (Lymphocyte-specific interferon regulatory factor) (LSIRF) (Multiple myeloma oncogene 1) (NF-EM5)IRF4 MUM1Q153062
Interferon-inducible double-stranded RNA-dependent protein kinase activator A (PKR-associated protein X) (PKR-associating protein X) (Protein activator of the interferon-induced protein kinase) (Protein kinase, interferon-inducible double-stranded RNA-dependent activator)PRKRA PACT RAX HSD-14 HSD14O755692
Interleukin-1 receptor accessory protein-like 1 (IL-1-RAPL-1) (IL-1RAPL-1) (IL1RAPL-1) (Oligophrenin-4) (Three immunoglobulin domain-containing IL-1 receptor-related 2) (TIGIRR-2) (X-linked interleukin-1 receptor accessory protein-like 1)IL1RAPL1 OPHN4Q9NZN12
Interleukin-1 receptor type 2 (IL-1R-2) (IL-1RT-2) (IL-1RT2) (CD121 antigen-like family member B) (CDw121b) (IL-1 type II receptor) (Interleukin-1 receptor beta) (IL-1R-beta) (Interleukin-1 receptor type II) (CD antigen CD121b) [Cleaved into: Interleukin-1 receptor type 2, membrane form (mIL-1R2) (mIL-1RII); Interleukin-1 receptor type 2, soluble form (sIL-1R2) (sIL-1RII)]IL1R2 IL1RBP279302
Interleukin-1 receptor-associated kinase-like 2 (IRAK-2)IRAK2O431872
Interleukin-10 (IL-10) (Cytokine synthesis inhibitory factor) (CSIF)IL10P223012
Interleukin-10 receptor subunit beta (IL-10 receptor subunit beta) (IL-10R subunit beta) (IL-10RB) (Cytokine receptor class-II member 4) (Cytokine receptor family 2 member 4) (CRF2-4) (Interleukin-10 receptor subunit 2) (IL-10R subunit 2) (IL-10R2) (CD antigen CDw210b)IL10RB CRFB4 D21S58 D21S66Q083342
Interleukin-17 receptor C (IL-17 receptor C) (IL-17RC) (Interleukin-17 receptor homolog) (IL17Rhom) (Interleukin-17 receptor-like protein) (IL-17RL) (ZcytoR14)IL17RC UNQ6118/PRO20040/PRO38901Q8NAC32
Interleukin-17F (IL-17F) (Cytokine ML-1) (Interleukin-24) (IL-24)IL17F IL24Q96PD42
Interleukin-18 receptor 1 (IL-18R-1) (IL-18R1) (CD218 antigen-like family member A) (CDw218a) (IL1 receptor-related protein) (IL-1Rrp) (IL1R-rp) (CD antigen CD218a)IL18R1 IL1RRPQ134782
Interleukin-18 receptor accessory protein (IL-18 receptor accessory protein) (IL-18RAcP) (Accessory protein-like) (AcPL) (CD218 antigen-like family member B) (CDw218b) (IL-1R accessory protein-like) (IL-1RAcPL) (Interleukin-1 receptor 7) (IL-1R-7) (IL-1R7) (Interleukin-18 receptor accessory protein-like) (Interleukin-18 receptor beta) (IL-18R-beta) (IL-18Rbeta) (CD antigen CD218b)IL18RAP IL1R7O952562
Interleukin-27 subunit alpha (IL-27 subunit alpha) (IL-27-A) (IL27-A) (p28)IL27 IL27AQ8NEV92
Interleukin-3 receptor subunit alpha (IL-3 receptor subunit alpha) (IL-3R subunit alpha) (IL-3R-alpha) (IL-3RA) (CD antigen CD123)IL3RA IL3RP269512
Interleukin-32 (IL-32) (Natural killer cells protein 4) (Tumor necrosis factor alpha-inducing factor)IL32 NK4 TAIFP240012
Interleukin-36 beta (FIL1 eta) (Interleukin-1 eta) (IL-1 eta) (Interleukin-1 family member 8) (IL-1F8) (Interleukin-1 homolog 2) (IL-1H2)IL36B IL1F8 IL1H2Q9NZH72
Interleukin-6 (IL-6) (B-cell stimulatory factor 2) (BSF-2) (CTL differentiation factor) (CDF) (Hybridoma growth factor) (Interferon beta-2) (IFN-beta-2)IL6 IFNB2P052312
Interleukin-6 receptor subunit alpha (IL-6 receptor subunit alpha) (IL-6R subunit alpha) (IL-6R-alpha) (IL-6RA) (IL-6R 1) (Membrane glycoprotein 80) (gp80) (CD antigen CD126)IL6RP088872
Intraflagellar transport protein 46 homologIFT46 C11orf2 C11orf60Q9NQC82
Intraflagellar transport protein 57 homolog (Dermal papilla-derived protein 8) (Estrogen-related receptor beta-like protein 1) (HIP1-interacting protein) (MHS4R2)IFT57 DERP8 ESRRBL1 HIPPIQ9NWB72
Inward rectifier potassium channel 4 (HIRK2) (HRK1) (Hippocampal inward rectifier) (HIR) (Inward rectifier K(+) channel Kir2.3) (IRK-3) (Potassium channel, inwardly rectifying subfamily J member 4)KCNJ4 IRK3P480502
IPO5 protein (Fragment)IPO5Q9BVS92
IQ domain-containing protein EIQCE KIAA1023Q6IPM22
IQ motif and SEC7 domain-containing protein 1 (ADP-ribosylation factors guanine nucleotide-exchange protein 100) (ADP-ribosylation factors guanine nucleotide-exchange protein 2) (Brefeldin-resistant Arf-GEF 2 protein)IQSEC1 ARFGEP100 BRAG2 KIAA0763Q6DN902
Iroquois-class homeodomain protein IRX-2 (Homeodomain protein IRXA2) (Iroquois homeobox protein 2)IRX2 IRXA2Q9BZI12
Iroquois-class homeodomain protein IRX-6 (Homeodomain protein IRXB3) (Iroquois homeobox protein 6)IRX6 IRX7 IRXB3P784122
Isoaspartyl peptidase/L-asparaginase (EC 3.4.19.5) (EC 3.5.1.1) (Asparaginase-like protein 1) (Beta-aspartyl-peptidase) (Isoaspartyl dipeptidase) (L-asparagine amidohydrolase) [Cleaved into: Isoaspartyl peptidase/L-asparaginase alpha chain; Isoaspartyl peptidase/L-asparaginase beta chain]ASRGL1 ALP CRASHQ7L2662
Isoleucine--tRNA ligase, cytoplasmic (EC 6.1.1.5) (Isoleucyl-tRNA synthetase) (IRS) (IleRS)IARSP412522
ITGA7 variant protein (Fragment)ITGA7 variant proteinQ4LE352
ITSN1 protein (Fragment)ITSN1Q6PD562
Janus kinase and microtubule-interacting protein 1 (GABA-B receptor-binding protein) (Multiple alpha-helices and RNA-linker protein 1) (Marlin-1)JAKMIP1 GABABRBP JAMIP1 MARLIN1Q96N162
Jerky protein homolog-like (Human homolog of mouse jerky gene protein) (HHMJG)JRKLQ9Y4A02
Junctional adhesion molecule A (JAM-A) (Junctional adhesion molecule 1) (JAM-1) (Platelet F11 receptor) (Platelet adhesion molecule 1) (PAM-1) (CD antigen CD321)F11R JAM1 JCAM UNQ264/PRO301Q9Y6242
Junctional adhesion molecule C (JAM-C) (JAM-2) (Junctional adhesion molecule 3) (JAM-3)JAM3 UNQ859/PRO1868Q9BX672
Junctophilin-2 (JP-2) (Junctophilin type 2)JPH2 JP2Q9BR392
Junctophilin-4 (JP-4) (Junctophilin-like 1 protein)JPH4 JPHL1 KIAA1831Q96JJ62
Kallistatin (Kallikrein inhibitor) (Peptidase inhibitor 4) (PI-4) (Serpin A4)SERPINA4 KST PI4P296222
Kazal-type serine protease inhibitor domain-containing protein 1KAZALD1 FKSG28 FKSG40 UNQ2945/PRO21184Q96I822
KCTD2 protein (Fragment)KCTD2Q8IYY22
Kelch-like protein 18KLHL18 KIAA0795 OK/SW-cl.74O948892
Kelch-like protein 28 (BTB/POZ domain-containing protein 5)KLHL28 BTBD5Q9NXS32
Kelch-like protein 40 (Kelch repeat and BTB domain-containing protein 5) (Sarcosynapsin)KLHL40 KBTBD5 SRYPQ2TBA02
Keratin, type I cuticular Ha7 (Hair keratin, type I Ha7) (Keratin-37) (K37)KRT37 HHA7 HKA7 KRTHA7O760142
Keratin, type I cytoskeletal 15 (Cytokeratin-15) (CK-15) (Keratin-15) (K15)KRT15 KRTBP190122
Keratin, type I cytoskeletal 26 (Cytokeratin-26) (CK-26) (Keratin-25B) (K25B) (Keratin-26) (K26) (Type I inner root sheath-specific keratin-K25irs2)KRT26 KRT25BQ7Z3Y92
Keratin, type II cytoskeletal 3 (65 kDa cytokeratin) (Cytokeratin-3) (CK-3) (Keratin-3) (K3) (Type-II keratin Kb3)KRT3P120352
Keratin, type II cytoskeletal 6A (Cytokeratin-6A) (CK-6A) (Cytokeratin-6D) (CK-6D) (Keratin-6A) (K6A) (Type-II keratin Kb6) (allergen Hom s 5)KRT6A K6A KRT6DP025382
Keratin, type II cytoskeletal 78 (Cytokeratin-78) (CK-78) (Keratin-5b) (Keratin-78) (K78) (Type-II keratin Kb40)KRT78 K5B KB40Q8N1N42
Keratin-associated protein 10-10 (High sulfur keratin-associated protein 10.10) (Keratin-associated protein 10.10) (Keratin-associated protein 18-10) (Keratin-associated protein 18.10)KRTAP10-10 KAP10.10 KAP18-10 KRTAP10.10 KRTAP18-1 KRTAP18.10P600142
Keratin-associated protein 13-4KRTAP13-4 KAP13.4Q3LI772
Keratin-associated protein 4-3 (Keratin-associated protein 4.3) (Ultrahigh sulfur keratin-associated protein 4.3)KRTAP4-3 KAP4.3 KRTAP4.3Q9BYR42
Keratin-associated protein 4-5 (Keratin-associated protein 4.5) (Ultrahigh sulfur keratin-associated protein 4.5)KRTAP4-5 KAP4.5 KRTAP4.5Q9BYR22
Keratin-associated protein 5-6 (Keratin-associated protein 5.6) (Ultrahigh sulfur keratin-associated protein 5.6)KRTAP5-6 KAP5.6 KRTAP5.6Q6L8G92
Keratin-associated protein 8-1 (High glycine-tyrosine keratin-associated protein 8.1)KRTAP8-1 KAP8.1 KRTAP8.1Q8IUC22
Keratin-associated protein 9-3 (Keratin-associated protein 9.3) (Ultrahigh sulfur keratin-associated protein 9.3)KRTAP9-3 KAP9.3 KRTAP9.3Q9BYQ32
KH homology domain-containing protein 1KHDC1 C6orf148Q4VXA52
Killer cell immunoglobulin-like receptor 2DL4 (CD158 antigen-like family member D) (G9P) (Killer cell inhibitory receptor 103AS) (KIR-103AS) (MHC class I NK cell receptor KIR103AS) (CD antigen CD158d)KIR2DL4 CD158D KIR103ASQ997062
Killer cell immunoglobulin-like receptor 2DS4 (CD158 antigen-like family member I) (MHC class I NK cell receptor) (Natural killer-associated transcript 8) (NKAT-8) (P58 natural killer cell receptor clones CL-39/CL-17) (p58 NK receptor CL-39/CL-17) (CD antigen CD158i)KIR2DS4 CD158I KKA3 NKAT8P436322
Killer cell lectin-like receptor subfamily G member 1 (C-type lectin domain family 15 member A) (ITIM-containing receptor MAFA-L) (MAFA-like receptor) (Mast cell function-associated antigen)KLRG1 CLEC15A MAFA MAFALQ96E932
Kin of IRRE-like protein 1 (Kin of irregular chiasm-like protein 1) (Nephrin-like protein 1)KIRREL KIRREL1 NEPH1Q96J842
Kin of IRRE-like protein 3 (Kin of irregular chiasm-like protein 3) (Nephrin-like protein 2)KIRREL3 KIAA1867 NEPH2 UNQ5923/PRO4502/PRO19814Q8IZU92
Kinase D-interacting substrate of 220 kDa (Ankyrin repeat-rich membrane-spanning protein)KIDINS220 ARMS KIAA1250Q9ULH02
Kinesin heavy chain isoform 5C (Kinesin heavy chain neuron-specific 2)KIF5C KIAA0531 NKHC2O602822
Kinesin light chain 4 (KLC 4) (Kinesin-like protein 8)KLC4 KNSL8Q9NSK02
Kinesin-like protein KIF17 (KIF3-related motor protein)KIF17 KIAA1405 KIF3XQ9P2E22
Kinesin-like protein KIF1A (Axonal transporter of synaptic vesicles) (Microtubule-based motor KIF1A) (Unc-104- and KIF1A-related protein) (hUnc-104)KIF1A ATSV C2orf20Q127562
Kinesin-like protein KIF21BKIF21B KIAA0449O750372
Kinesin-like protein KIF26AKIF26A KIAA1236Q9ULI42
Kinesin-like protein KIF2BKIF2BQ8N4N82
Kinesin-like protein KIF6KIF6 C6orf102Q6ZMV92
Kinesin-like protein KIFC1 (Kinesin-like protein 2) (Kinesin-related protein HSET)KIFC1 HSET KNSL2Q9BW192
Kinesin-like protein KIFC3KIFC3Q9BVG82
Kinetochore associated 2, isoform CRA_a (cDNA FLJ77925, highly similar to Homo sapiens kinetochore associated 2, mRNA) (cDNA, FLJ93683, Homo sapiens kinetochore associated 2 (KNTC2), mRNA)KNTC2 hCG_38410A8K0312
Kinetochore protein Spc25 (hSpc25)SPC25 SPBC25 AD024Q9HBM12
KIR2DL3KIR2DL3E3NZD82
KiSS-1 receptor (KiSS-1R) (G-protein coupled receptor 54) (G-protein coupled receptor OT7T175) (hOT7T175) (Hypogonadotropin-1) (Kisspeptins receptor) (Metastin receptor)KISS1R AXOR12 GPR54Q969F82
KLHDC8B protein (Fragment)KLHDC8BQ96DZ82
Klotho (EC 3.2.1.31) [Cleaved into: Klotho peptide]KLQ9UEF72
KN motif and ankyrin repeat domain-containing protein 3 (Ankyrin repeat domain-containing protein 47)KANK3 ANKRD47Q6NY192
KN motif and ankyrin repeat domain-containing protein 4 (Ankyrin repeat domain-containing protein 38)KANK4 ANKRD38Q5T7N32
Krueppel-like factor 2 (Lung krueppel-like factor)KLF2 LKLFQ9Y5W32
Kv channel-interacting protein 4 (KChIP4) (A-type potassium channel modulatory protein 4) (Calsenilin-like protein) (Potassium channel-interacting protein 4)KCNIP4 CALP KCHIP4Q6PIL62
L-amino-acid oxidase (LAAO) (LAO) (EC 1.4.3.2) (Interleukin-4-induced protein 1) (IL4-induced protein 1) (Protein Fig-1) (hFIG1)IL4I1 FIG1 UNQ636/PRO1265Q96RQ92
L-fucose kinase (Fucokinase) (EC 2.7.1.52)FUKQ8N0W32
Laccase domain-containing protein 1LACC1 C13orf31Q8IV202
Lambda-crystallin homolog (EC 1.1.1.45) (L-gulonate 3-dehydrogenase) (Gul3DH)CRYL1 CRYQ9Y2S22
Lamin B2, isoform CRA_a (Lamin-B2)LMNB2 hCG_2004338J9JID72
Lamin-B1LMNB1 LMN2 LMNBP207002
Laminin subunit beta-1 (Laminin B1 chain) (Laminin-1 subunit beta) (Laminin-10 subunit beta) (Laminin-12 subunit beta) (Laminin-2 subunit beta) (Laminin-6 subunit beta) (Laminin-8 subunit beta)LAMB1P079422
Laminin subunit gamma-1 (Laminin B2 chain) (Laminin-1 subunit gamma) (Laminin-10 subunit gamma) (Laminin-11 subunit gamma) (Laminin-2 subunit gamma) (Laminin-3 subunit gamma) (Laminin-4 subunit gamma) (Laminin-6 subunit gamma) (Laminin-7 subunit gamma) (Laminin-8 subunit gamma) (Laminin-9 subunit gamma) (S-laminin subunit gamma) (S-LAM gamma)LAMC1 LAMB2P110472
LanC-like protein 2 (Testis-specific adriamycin sensitivity protein)LANCL2 GPR69B TASPQ9NS862
Late cornified envelope protein 1B (Late envelope protein 2) (Small proline-rich-like epidermal differentiation complex protein 2A)LCE1B LEP2 SPRL2AQ5T7P32
Late cornified envelope protein 2C (Late envelope protein 11)LCE2C LEP11Q5TA812
Late cornified envelope protein 3D (Late envelope protein 16) (Small proline-rich-like epidermal differentiation complex protein 6A) (Small proline-rich-like epidermal differentiation complex protein 6B)LCE3D LEP16 SPRL6A SPRL6BQ9BYE32
Late secretory pathway protein AVL9 homologAVL9 KIAA0241Q8NBF62
Latent-transforming growth factor beta-binding protein 1 (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1)LTBP1Q147662
Latent-transforming growth factor beta-binding protein 2 (LTBP-2)LTBP2 C14orf141 LTBP3Q147672
Lateral signaling target protein 2 homolog (hLst2) (Zinc finger FYVE domain-containing protein 28)ZFYVE28 KIAA1643 LST2Q9HCC92
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