EVpedia provide top 100+ EV markers, selected according to their identification number.
Based on EV proteomes, we defined the identification number of protein A as the number of datasets which contain protein A.
Therefore, proteins with higher identification numbers were more conserved.

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Protein name Gene symbol UniProt accession Identification number
Lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase (EC 2.4.1.206) (Lactotriaosylceramide synthase) (Lc(3)Cer synthase) (Lc3 synthase) (UDP-GlcNAc:beta-Gal beta-1,3-N-acetylglucosaminyltransferase 5) (BGnT-5) (Beta-1,3-Gn-T5) (Beta-1,3-N-acetylglucosaminyltransferase 5) (Beta3Gn-T5)B3gnt5Q8BGY63
Lactosylceramide 4-alpha-galactosyltransferase (EC 2.4.1.228) (Alpha-1,4-N-acetylglucosaminyltransferase) (Alpha-1,4-galactosyltransferase) (Alpha4Gal-T1) (Globotriaosylceramide synthase) (Gb3 synthase) (UDP-galactose:beta-D-galactosyl-beta1-R 4-alpha-D-galactosyltransferase)A4galtQ67BJ43
Lactotransferrin (Lactoferrin) (EC 3.4.21.-)LtfP080713
Laforin (EC 3.1.3.16) (EC 3.1.3.48) (Lafora PTPase) (LAFPTPase)Epm2aQ9WUA53
Lanosterol 14-alpha demethylase (LDM) (EC 1.14.13.70) (CYPLI) (Cytochrome P450 51A1) (Cytochrome P450-14DM) (Cytochrome P45014DM) (Cytochrome P450LI) (Sterol 14-alpha demethylase)Cyp51a1 Cyp51Q8K0C43
Large neutral amino acids transporter small subunit 4 (L-type amino acid transporter 4) (Solute carrier family 43 member 2)Slc43a2 Lat4Q8CGA33
Lengsin (Glutamate-ammonia ligase domain-containing protein 1) (Lens glutamine synthase-like)Lgsn Gluld1 LgsQ8CIX83
Lethal(3)malignant brain tumor-like protein 1 (H-l(3)mbt) (H-l(3)mbt protein) (L(3)mbt-like) (L(3)mbt protein homolog)L3mbtl1 Kiaa0681 L3mbt L3mbtlA2A5N83
LETM1 domain-containing protein 1 (Cervical cancer receptor) (MCC-32)Letmd1 MccrQ924L13
Leucine zipper transcription factor-like protein 1Lztfl1Q9JHQ53
Leucine--tRNA ligase, cytoplasmic (EC 6.1.1.4) (Leucyl-tRNA synthetase) (LeuRS)LarsQ8BMJ23
Leucine-rich glioma-inactivated protein 1Lgi1Q9JIA13
Leucine-rich repeat flightless-interacting protein 1 (LRR FLII-interacting protein 1) (FLI-LRR-associated protein 1) (Flap-1) (H186 FLAP)Lrrfip1 FlapQ3UZ393
Leucine-rich repeat protein SHOC-2 (Protein soc-2 homolog) (Protein sur-8 homolog)Shoc2O885203
Leucine-rich repeat-containing protein 2Lrrc2Q8VDB83
Leucine-rich repeat-containing protein 47Lrrc47 Kiaa1185Q505F53
Leucine-rich repeat-containing protein 7Lrrc7E9Q6L93
Leukemia inhibitory factor (LIF) (Differentiation-stimulating factor) (D factor)LifP090563
Leukocyte tyrosine kinase receptor (EC 2.7.10.1)LtkP089233
Leukosialin (B-cell differentiation antigen LP-3) (Leukocyte sialoglycoprotein) (Lymphocyte antigen 48) (Ly-48) (Sialophorin) (CD antigen CD43)SpnP157023
LIM domain-binding protein 2 (LDB-2) (Carboxyl-terminal LIM domain-binding protein 1) (CLIM-1) (LIM domain-binding factor CLIM1)Ldb2 Clim1O552033
LIM domain-containing protein 2Limd2Q8BGB53
Lipid phosphate phosphatase-related protein type 1 (Plasticity-related gene 3 protein) (PRG-3)Lppr1 Kiaa4247 Prg3Q8BFZ23
Lipolysis-stimulated lipoprotein receptor (Lipolysis-stimulated receptor) (Liver-specific bHLH-Zip transcription factor) (Liver-specific gene on mouse chromosome 7 protein)Lsr Lisch7Q99KG53
Lithostathine-1 (Islet of Langerhans regenerating protein 1) (REG 1) (Pancreatic stone protein 1) (PSP) (Pancreatic thread protein 1) (PTP) (Regenerating protein 1)Reg1P431373
Lithostathine-2 (Islet of Langerhans regenerating protein 2) (REG-2) (Pancreatic stone protein 2) (PSP) (Pancreatic thread protein 2) (PTP)Reg2Q087313
Lon protease homolog 2, peroxisomal (EC 3.4.21.-) (Lon protease-like protein 2) (Lon protease 2) (Peroxisomal Lon protease)Lonp2Q9DBN53
Long-chain-fatty-acid--CoA ligase 1 (EC 6.2.1.3) (Long-chain acyl-CoA synthetase 1) (LACS 1)Acsl1 Acsl2 Facl2P412163
Long-chain-fatty-acid--CoA ligase ACSBG1 (EC 6.2.1.3) (Acyl-CoA synthetase bubblegum family member 1) (mBG1) (Gonadotropin-regulated long chain acyl CoA synthetase) (GR-LACS) (Lipidosin)Acsbg1 Kiaa0631 LpdQ99PU53
Low affinity cationic amino acid transporter 2 (CAT-2) (CAT2) (20.5) (Solute carrier family 7 member 2) (T-cell early activation protein) (TEA)Slc7a2 Atrc2 TeaP185813
Low affinity immunoglobulin gamma Fc region receptor II (Fc gamma receptor IIB) (Fc-gamma RII) (Fc-gamma-RIIB) (FcRII) (IgG Fc receptor II beta) (Lymphocyte antigen 17) (Ly-17) (CD antigen CD32)Fcgr2 Fcgr2b Ly-17P081013
Ly6/PLAUR domain-containing protein 3 (GPI-anchored metastasis-associated protein C4.4A homolog)Lypd3 C4.4aQ91YK83
Ly6/PLAUR domain-containing protein 4Lypd4Q8BVP63
Lymphatic vessel endothelial hyaluronic acid receptor 1 (LYVE-1) (Cell surface retention sequence-binding protein 1) (CRSBP-1) (Extracellular link domain-containing protein 1)Lyve1 Crsbp1 Xlkd1Q8BHC03
Lymphocyte antigen 6F (Ly-6F) (Ly-6F.1)Ly6fP354603
Lymphocyte transmembrane adapter 1 (Linker for activation of X cells) (Membrane-associated adapter protein LAX)Lax1 LaxQ8BHB33
Lymphocyte-specific helicase (EC 3.6.4.-) (Proliferation-associated SNF2-like protein)Hells Lsh PasgQ608483
Lymphotoxin-alpha (LT-alpha) (TNF-beta) (Tumor necrosis factor ligand superfamily member 1)Lta Tnfb Tnfsf1P092253
Lysine-specific demethylase 2B (EC 1.14.11.27) (F-box and leucine-rich repeat protein 10) (F-box protein FBL10) (F-box/LRR-repeat protein 10) (JmjC domain-containing histone demethylation protein 1B) ([Histone-H3]-lysine-36 demethylase 1B)Kdm2b Fbl10 Fbxl10 Jhdm1b Kiaa3014Q6P1G23
Lysophospholipid acyltransferase 2 (LPLAT 2) (EC 2.3.1.-) (1-acylglycerophosphocholine O-acyltransferase) (EC 2.3.1.23) (1-acylglycerophosphoethanolamine O-acyltransferase) (EC 2.3.1.n7) (Lysophosphatidylcholine acyltransferase) (LPCAT) (Lyso-PC acyltransferase) (Lysophosphatidylcholine acyltransferase 4) (Lyso-PC acyltransferase 4) (mLPCAT4) (Lysophosphatidylethanolamine acyltransferase) (LPEAT) (Lyso-PE acyltransferase) (Membrane-bound O-acyltransferase domain-containing protein 2) (O-acyltransferase domain-containing protein 2)Mboat2 Lpcat4 Oact2Q8R3I23
Lysophospholipid acyltransferase 7 (LPLAT 7) (EC 2.3.1.-) (Bladder and breast carcinoma-overexpressed gene 1 protein) (Leukocyte receptor cluster member 4) (Membrane-bound O-acyltransferase domain-containing protein 7) (O-acyltransferase domain-containing protein 7) (m-mboa-7)Mboat7 Bb1 Leng4 Oact7Q8CHK33
Lysosomal alpha-glucosidase (EC 3.2.1.20) (Acid maltase)GaaP706993
Lysosomal protein NCU-G10Q9JHJ33
Lysozyme-like protein 1 (EC 3.2.1.17)Lyzl1 Lyc2Q9CPX33
M-phase inducer phosphatase 2 (EC 3.1.3.48) (Dual specificity phosphatase Cdc25B)Cdc25b Cdc25m2P303063
m7GpppX diphosphatase (EC 3.6.1.59) (DCS-1) (Decapping scavenger enzyme) (Hint-related 7meGMP-directed hydrolase) (Histidine triad nucleotide-binding protein 5) (Histidine triad protein member 5) (HINT-5) (Scavenger mRNA-decapping enzyme DcpS)Dcps Dcs1 Hint5Q9DAR73
MAGEB3 (Protein Mageb3)Mageb3Q9D2H43
Magnesium transporter NIPA4 (Ichthyin) (NIPA-like protein 4) (Non-imprinted in Prader-Willi/Angelman syndrome region protein 4 homolog)Nipal4 Ichn Nipa4Q8BZF23
Magnesium-dependent phosphatase 1 (MDP-1) (EC 3.1.3.-) (EC 3.1.3.48)Mdp1Q9D9673
MAGUK p55 subfamily member 4 (Discs large homolog 6) (mDLG6)Mpp4 Dlg6Q6P7F13
MAGUK p55 subfamily member 7Mpp7Q8BVD53
Major centromere autoantigen B (Centromere protein B) (CENP-B)Cenpb Cenp-bP277903
Male-enhanced antigen 1 (MEA-1)Mea1 MeaQ643273
Malignant T-cell-amplified sequence 2 (MCT-2) (Multiple copies T-cell malignancies 2)Mcts2Q9CQ213
Mammalian ependymin-related protein 1 (MERP-1)Epdr1 Epdr2 Merp1 Merp2Q99M713
MAP kinase-activated protein kinase 3 (MAPK-activated protein kinase 3) (MAPKAP kinase 3) (MAPKAP-K3) (MAPKAPK-3) (MK-3) (EC 2.7.11.1)Mapkapk3Q3UMW73
MAP kinase-interacting serine/threonine-protein kinase 2 (EC 2.7.11.1) (MAP kinase signal-integrating kinase 2) (MAPK signal-integrating kinase 2) (Mnk2)Mknk2 Mnk2Q8CDB03
MAP/microtubule affinity-regulating kinase 4 (EC 2.7.11.1)Mark4 Kiaa1860Q8CIP43
MAP7 domain-containing protein 1Map7d1 Kiaa1187 Mtap7d1A2AJI03
MAPK-interacting and spindle-stabilizing protein-like (Mitogen-activated protein kinase 1-interacting protein 1-like)Mapk1ip1lQ8BH933
Mas-related G-protein coupled receptor member A2Mrgpra2 Mrga2Q91WW43
Mas-related G-protein coupled receptor member A8Mrgpra8 Mrga8Q91ZC43
Matrix metalloproteinase-16 (MMP-16) (EC 3.4.24.-) (Membrane-type matrix metalloproteinase 3) (MT-MMP 3) (MTMMP3) (Membrane-type-3 matrix metalloproteinase) (MT3-MMP) (MT3MMP)Mmp16Q9WTR03
Max dimerization protein 4Mxd4Q91VN73
MCG1028220 (Olfactory receptor Olfr298) (Protein Olfr298)Olfr298 mCG_1028220Q7TS063
MCG1029944 (Olfactory receptor MOR136-7) (Olfactory receptor Olfr345) (Protein Olfr345)Olfr345 mCG_1029944Q8VGK43
MCG1034048 (Olfactory receptor 111) (Olfactory receptor Olfr111) (Protein Olfr111)Olfr111 mCG_1034048Q7TRK13
MCG1034066 (Olfactory receptor 138) (Olfactory receptor Olfr138) (Olfr138 protein) (Protein Olfr138)Olfr138 mCG_1034066Q7TRI73
MCG1035775 (Olfactory receptor Olfr374) (Protein Olfr374)Olfr374 mCG_1035775Q7TRY03
MCG1037685 (Olfactory receptor MOR129-3) (Olfactory receptor Olfr51) (Protein Olfr51)Olfr51 mCG_1037685Q8VGG93
MCG1038186 (Olfactory receptor 206) (Olfactory receptor MOR182-4) (Olfactory receptor Olfr206) (Protein Olfr206)Olfr206 mCG_1038186Q8VGP93
MCG1045095 (Olfactory receptor Olfr1480) (Protein Olfr1480)Olfr1480 mCG_1045095Q7TQQ63
MCG1046665 (Olfactory receptor MOR263-1) (Olfactory receptor P3) (Protein Olfr713)Olfr713 mCG_1046665Q920G53
MCG1048713 (Olfactory receptor 767) (Olfactory receptor MOR115-1) (Olfactory receptor Olfr767) (Protein Olfr767)Olfr767 mCG_1048713Q8VG333
MCG1048719 (Olfactory receptor Olfr776) (Protein Olfr776)Olfr776 mCG_1048719Q7TRI33
MCG115462 (Magea5 protein) (Melanoma antigen, family A, 5) (Protein Magea5)Magea5 mCG_115462O890093
MCG120168 (Protein Lce1i)Lce1i mCG_120168Q9D6P53
MCG122846 (Protein Sipa1l3)Sipa1l3 mCG_122846G3X9J03
MCG125498, isoform CRA_a (Protein Zfp931)Zfp931 mCG_125498A2AHM23
MCG132387 (Predicted gene, EG624855) (Protein Gm6531)Gm6531 EG624855 mCG_132387Q3UNC93
MCG133388, isoform CRA_c (Protocadherin gamma A2) (Protocadherin gamma subfamily A, 2)Pcdhga2 mCG_133388Q91XY63
MCG133576, isoform CRA_aAup1 mCG_133576Q3TBX53
MCG140055 (Olfactory receptor Olfr1198) (Protein Olfr1198)Olfr1198 mCG_140055Q7TR123
MCG140627 (Olfactory receptor Olfr1382) (Protein Olfr1382)Olfr1382 mCG_140627Q7TQT33
MCG140848 (Protein Rdh1) (Retinol dehydrogenase 1 (All trans)) (Retinol dehydrogenase type 1)Rdh1 mCG_140848Q8CGV43
MCG140866 (Olfactory receptor MOR255-6) (Olfactory receptor Olfr401) (Protein Olfr401)Olfr401 mCG_140866Q8VFX63
MCG141447 (Olfactory receptor MOR12-1) (Olfactory receptor Olfr639) (Protein Olfr639)Olfr639 mCG_141447Q8VGY83
MCG141722 (Olfactory receptor Olfr192)Olfr192 mCG_141722Q7TS443
MCG141924 (Olfactory receptor 1330) (Olfactory receptor MOR259-8) (Olfactory receptor Olfr1330) (Protein Olfr1330)Olfr1330 mCG_141924Q8VEY63
MCG142006 (Protein Olfr171)Olfr171 Olfr169 mCG_142006G5E8J13
MCG142277 (Olfactory receptor Olfr1085) (Protein Olfr1085)Olfr1085 mCG_142277Q7TR643
MCG147493 (Protein Pih1d3) (Uncharacterized protein)Pih1d3 4930521A18Rik mCG_147493Q3KNI63
MCG18845, isoform CRA_d (Protein Uba7) (Ubiquitin-activating enzyme E1-like)Uba7 Ube1l mCG_18845Q9DBK73
MCG2065, isoform CRA_c (PreS1 binding protein) (Protein Gltscr2)Gltscr2 mCG_2065Q8BK353
MCG23028 (Protein Zkscan4)Zkscan4 mCG_23028Q5SZT63
MCG3737 (Protein Vmn1r62) (Vomeronasal 1 receptor, D2) (Vomeronasal 1 receptor, D8) (Vomeronasal receptor V1RD8)Vmn1r62 V1rd2 V1rd8 mCG_3737Q8R2C03
MCG52488 (Olfactory receptor MOR257-4) (Olfactory receptor Olfr458) (Protein Olfr458)Olfr458 mCG_52488Q8VF803
MCG53682 (Olfactory receptor 60) (Olfactory receptor MOR253-6) (Protein Olfr60)Olfr60 mCG_53682Q8VGL43
MCG54796 (Olfactory receptor 569) (Olfactory receptor MOR30-1) (Olfactory receptor Olfr569) (Protein Olfr569)Olfr569 mCG_54796Q8VGZ23
MCG56945 (Protein Gm382)Gm382 mCG_56945B1AXN33
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