EVpedia provide top 100+ EV markers, selected according to their identification number.
Based on EV proteomes, we defined the identification number of protein A as the number of datasets which contain protein A.
Therefore, proteins with higher identification numbers were more conserved.

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Protein name Gene symbol UniProt accession Identification number
Peptidyl-prolyl cis-trans isomerase FKBP6 (PPIase FKBP6) (EC 5.2.1.8) (36 kDa FK506-binding protein) (36 kDa FKBP) (FKBP-36) (FK506-binding protein 6) (FKBP-6) (Immunophilin FKBP36) (Rotamase)Fkbp6Q91XW83
Peptidyl-prolyl cis-trans isomerase G (PPIase G) (Peptidyl-prolyl isomerase G) (EC 5.2.1.8) (Cyclophilin G) (Rotamase G)PpigA2AR023
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 4 (EC 5.2.1.8) (Parvulin-14) (Par14) (Peptidyl-prolyl cis-trans isomerase Pin4) (PPIase Pin4) (Rotamase Pin4)Pin4Q9CWW63
Pericentriolar material 1 protein (PCM-1) (mPCM-1)Pcm1Q9R0L63
Peripheral plasma membrane protein CASK (EC 2.7.11.1) (Calcium/calmodulin-dependent serine protein kinase)CaskO705893
Peroxiredoxin-6 (EC 1.11.1.15) (1-Cys peroxiredoxin) (1-Cys PRX) (Acidic calcium-independent phospholipase A2) (aiPLA2) (EC 3.1.1.-) (Antioxidant protein 2) (Non-selenium glutathione peroxidase) (NSGPx) (EC 1.11.1.9)Prdx6 Aop2 Ltw4 Prdx5O087093
PH and SEC7 domain-containing protein 3 (Exchange factor for ADP-ribosylation factor guanine nucleotide factor 6) (Pleckstrin homology and SEC7 domain-containing protein 3)Psd3 Efa6d Kiaa0942Q2PFD73
PHD finger protein 11 (PHD finger protein 11-like) (PHD finger protein 11D)Phf11 D14Ertd668e Phf11d Phf11lA6H5X43
Phosducin (PHD) (33 kDa phototransducing protein) (Rod photoreceptor 1) (RPR-1)Pdc Rpr1Q9QW083
Phosphatidylinositide phosphatase SAC2 (EC 3.1.3.-) (Inositol polyphosphate 5-phosphatase F) (Sac domain-containing inositol phosphatase 2) (Sac domain-containing phosphoinositide 5-phosphatase 2)Inpp5f Kiaa0966 Sac2Q8CDA13
Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 (EC 3.1.3.86) (Inositol polyphosphate-5-phosphatase of 145 kDa) (SIP-145) (SH2 domain-containing inositol 5'-phosphatase 1) (SH2 domain-containing inositol phosphatase 1) (SHIP-1) (p150Ship)Inpp5d 7a33 Ship Ship1Q9ES523
Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 2 protein (P-Rex2) (PtdIns(3,4,5)-dependent Rac exchanger 2) (DEP domain-containing protein 2)Prex2 Depdc2Q3LAC43
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (PI3-kinase subunit delta) (PI3K-delta) (PI3Kdelta) (PtdIns-3-kinase subunit delta) (EC 2.7.1.153) (Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit delta) (PtdIns-3-kinase subunit p110-delta) (p110delta)Pik3cdO359043
Phosphatidylinositol 4-kinase beta (PI4K-beta) (PI4Kbeta) (PtdIns 4-kinase beta) (EC 2.7.1.67)Pi4kb Pik4cbQ8BKC83
Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha (PIP5K1-alpha) (PtdIns(4)P-5-kinase 1 alpha) (EC 2.7.1.68) (68 kDa type I phosphatidylinositol 4-phosphate 5-kinase) (Phosphatidylinositol 4-phosphate 5-kinase type I alpha) (PIP5KIalpha) (Phosphatidylinositol 4-phosphate 5-kinase type I beta) (PI4P5KIbeta)Pip5k1a Pip5k1bP701823
Phosphatidylserine decarboxylase proenzyme (EC 4.1.1.65) [Cleaved into: Phosphatidylserine decarboxylase alpha chain; Phosphatidylserine decarboxylase beta chain]PisdQ8BSF43
Phosphoinositide-interacting proteinPirtQ8BFY03
Phospholipase A-2-activating protein (PLA2P) (PLAP)Plaa PlapP276123
Phospholipase A1 member A (EC 3.1.1.-) (Phosphatidylserine-specific phospholipase A1) (PS-PLA1)Pla1a Pspla1Q8VI783
Phospholipase D4 (PLD 4) (EC 3.1.4.4) (Choline phosphatase 4) (Phosphatidylcholine-hydrolyzing phospholipase D4)Pld4Q8BG073
Phospholipase DDHD2 (EC 3.1.1.-) (DDHD domain-containing protein 2) (SAM, WWE and DDHD domain-containing protein 1)Ddhd2 Kiaa0725 Samwd1Q80Y983
Phosphomannomutase 1 (PMM 1) (EC 5.4.2.8)Pmm1O356213
Phosphoribosyl pyrophosphate synthase-associated protein 1 (PRPP synthase-associated protein 1) (39 kDa phosphoribosypyrophosphate synthase-associated protein) (PAP39)Prpsap1Q9D0M13
Phosphorylase b kinase regulatory subunit alpha, skeletal muscle isoform (Phosphorylase kinase alpha M subunit)Phka1P188263
PI-PLC X domain-containing protein 1 (Phosphatidylinositol-specific phospholipase C, X domain containing 1, isoform CRA_b)Plcxd1 mCG_23690G3X9J33
PIN2/TERF1-interacting telomerase inhibitor 1 (67-11-3 protein) (LPTS1) (Liver-related putative tumor suppressor) (Pin2-interacting protein X1) (TRF1-interacting protein 1)Pinx1 LptsQ9CZX53
Pituitary homeobox 2 (ALL1-responsive protein ARP1) (BRX1 homeoprotein) (Homeobox protein PITX2) (Orthodenticle-like homeobox 2) (Paired-like homeodomain transcription factor 2) (Paired-like homeodomain transcription factor Munc 30) (Solurshin)Pitx2 Arp1 Brx1 Otlx2 Ptx2 RgsP974743
Plasma alpha-L-fucosidase (EC 3.2.1.51) (Alpha-L-fucoside fucohydrolase 2) (Alpha-L-fucosidase 2)Fuca2Q99KR83
Platelet-activating factor acetylhydrolase IB subunit alpha (Lissencephaly-1 protein) (LIS-1) (PAF acetylhydrolase 45 kDa subunit) (PAF-AH 45 kDa subunit) (PAF-AH alpha) (PAFAH alpha)Pafah1b1 Lis-1 Lis1 PafahaP630053
Pleiomorphic adenoma gene-like 1, isoform CRA_d (Protein Plagl1) (Zinc finger protein ZAC1)Plagl1 Zac1 mCG_12864Q9JLQ43
Pleiotropic regulator 1Plrg1Q922V43
Plexin-B2Plxnb2B2RXS43
Plexin-D1Plxnd1Q3UH933
Poliovirus receptor-related protein 2 (Herpes virus entry mediator B) (Herpesvirus entry mediator B) (HveB) (Murine herpes virus entry protein B) (mHveB) (Nectin-2) (Poliovirus receptor homolog) (CD antigen CD112)Pvrl2 Mph Pvr PvsP325073
Poly(rC)-binding protein 3 (Alpha-CP3)Pcbp3P577223
Polypeptide N-acetylgalactosaminyltransferase 12 (EC 2.4.1.41) (Polypeptide GalNAc transferase 12) (GalNAc-T12) (pp-GaNTase 12) (Protein-UDP acetylgalactosaminyltransferase 12) (UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 12)Galnt12Q8BGT93
Polypeptide N-acetylgalactosaminyltransferase 18 (EC 2.4.1.41) (Polypeptide GalNAc transferase-like protein 4) (GalNAc-T-like protein 4) (pp-GaNTase-like protein 4) (Polypeptide N-acetylgalactosaminyltransferase-like protein 4) (Protein-UDP acetylgalactosaminyltransferase-like protein 4) (UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase-like protein 4)Galnt18 Galntl4Q8K1B93
Post-GPI attachment to proteins factor 2 (FGF receptor-activating protein 1)Pgap2 Frag1Q3TQR03
Postmeiotic segregation increased 1 (S. cerevisiae) (Protein Pms1)Pms1Q8K1193
Potassium voltage-gated channel subfamily E member 3 (MinK-related peptide 2) (Minimum potassium ion channel-related peptide 2) (Potassium channel subunit beta MiRP2)Kcne3Q9WTW23
Potassium voltage-gated channel subfamily H member 3 (Potassium voltage-gated channel, subfamily H (Eag-related), member 3) (Potassium voltage-gated channel, subfamily H (Eag-related), member 3, isoform CRA_a)Kcnh3 mCG_18387B2RU853
Potassium voltage-gated channel subfamily S member 3 (Voltage-gated potassium channel subunit Kv9.3)Kcns3Q8BQZ83
Potassium voltage-gated channel, shaker-related subfamily, member 10 (Protein Kcna10)Kcna10B2RQA13
Potassium-transporting ATPase alpha chain 2 (EC 3.6.3.10) (Non-gastric H(+)/K(+) ATPase subunit alpha) (Proton pump)Atp12a Atp1al1Q9Z1W83
POU domain, class 4, transcription factor 1 (Brain-specific homeobox/POU domain protein 3A) (Brain-3A) (Brn-3A) (Brn-3.0)Pou4f1 Brn-3 Brn3 Brn3aP172083
PR domain zinc finger protein 16 (PR domain-containing protein 16) (Transcription factor MEL1) (MDS1/EVI1-like gene 1)Prdm16 Kiaa1675 Mel1A2A9353
Predicted gene, EG382275 (Protein Gm5168)Gm5168 EG382275Q4KL043
Predicted gene, EG434179 (Protein Gm5595)Gm5595 EG434179Q6NVD63
Predicted gene, EG545253Gm5820 EG545253Q3ULQ83
Predicted gene, OTTMUSG00000002038 (Protein Gm11541) (Putative uncharacterized protein RP23-290B5.6)Gm11541 OTTMUSG00000002038 RP23-290B5.6 mCG_147536Q8C4D83
Predicted gene, OTTMUSG00000010657 (Protein Gm13139)Gm13139 OTTMUSG00000010657Q8R1N33
Predicted gene, OTTMUSG00000010671Gm13152 OTTMUSG00000010671Q6PDN13
Pregnancy specific glycoprotein 18 (Protein Psg18)Psg18B2RSG73
Pregnancy-specific glycoprotein 25 (Protein Psg25)Psg25Q497W13
Pregnancy-specific glycoprotein 26 (Protein Psg26)Psg26 EG574429Q4KL653
Pregnancy-specific glycoprotein 27 (Protein Psg27)Psg27 EG545925Q497W23
Pregnancy-specific glycoprotein 28 (Protein Psg28)Psg28Q4KL663
Probable 2-oxoglutarate dehydrogenase E1 component DHKTD1, mitochondrial (EC 1.2.4.2) (Dehydrogenase E1 and transketolase domain-containing protein 1)Dhtkd1 Kiaa1630A2ATU03
Probable ATP-dependent RNA helicase DHX34 (EC 3.6.4.13) (DEAH box protein 34)Dhx34 Ddx34 Kiaa0134Q9DBV33
Probable carboxypeptidase X1 (EC 3.4.17.-) (Metallocarboxypeptidase CPX-1)Cpxm1 Cpx1 CpxmQ9Z1003
Probable crossover junction endonuclease EME2 (EC 3.1.22.-)Eme2Q56A043
Probable E3 ubiquitin-protein ligase makorin-2 (EC 6.3.2.-)Mkrn2Q9ERV13
Probable G-protein coupled receptor 113 (G-protein coupled receptor PGR23)Gpr113 Gm1041 Pcr113 Pgr23Q58Y753
Probable G-protein coupled receptor 135Gpr135Q7TQP23
Probable G-protein coupled receptor 27 (Super conserved receptor expressed in brain 1)Gpr27 Sreb1O548973
Probable glutathione peroxidase 8 (GPx-8) (GSHPx-8) (EC 1.11.1.9)Gpx8Q9D7B73
Probable inactive ribonuclease-like protein 13Rnase13Q5GAM73
Probable methyltransferase-like protein 15 (EC 2.1.1.-) (Methyltransferase 5 domain-containing protein 1)Mettl15 Mett5d1Q9DCL43
Probable N-acetyltransferase CML3 (EC 2.3.1.-) (Camello-like protein 3)Cml3Q9JIY83
Probable palmitoyltransferase ZDHHC14 (EC 2.3.1.225) (NEW1 domain-containing protein) (NEW1CP) (Zinc finger DHHC domain-containing protein 14) (DHHC-14)Zdhhc14Q8BQQ13
Probable ubiquitin carboxyl-terminal hydrolase FAF-X (EC 3.4.19.12) (Deubiquitinating enzyme FAF-X) (Fat facets homolog) (Fat facets protein-related, X-linked) (Ubiquitin carboxyl-terminal hydrolase FAM) (Ubiquitin thioesterase FAF-X) (Ubiquitin-specific protease 9, X chromosome) (Ubiquitin-specific-processing protease FAF-X)Usp9x Fafl FamP703983
Probable UDP-sugar transporter protein SLC35A4 (Solute carrier family 35 member A4)Slc35a4Q9D3213
Progestin and adipoQ receptor family member 6 (Progestin and adipoQ receptor family member VI)Paqr6Q6TCG53
Programmed cell death 1 ligand 1 (PD-L1) (PDCD1 ligand 1) (Programmed death ligand 1) (B7 homolog 1) (B7-H1) (CD antigen CD274)Cd274 B7h1 Pdcd1l1 Pdcd1lg1 Pdl1Q9EP733
Prolactin-releasing peptide receptor (PrRP receptor) (PrRPR) (G-protein coupled receptor 10)Prlhr Gm339 Gpr10Q6VMN63
Proline rich proteinMP4Q618883
Proline/serine-rich coiled-coil protein 1Psrc1 Dda3Q9D0P73
Prolyl 4-hydroxylase subunit alpha-1 (4-PH alpha-1) (EC 1.14.11.2) (Procollagen-proline,2-oxoglutarate-4-dioxygenase subunit alpha-1)P4ha1Q607153
Prolyl endopeptidase (PE) (EC 3.4.21.26) (Post-proline cleaving enzyme)Prep PepQ9QUR63
Prolyl-tRNA synthetase associated domain-containing protein 1 (PrdX deacylase domain-containing protein 1)Prorsd1 Prdxdd1Q9D8203
Propionyl-CoA carboxylase beta chain, mitochondrial (PCCase subunit beta) (EC 6.4.1.3) (Propanoyl-CoA:carbon dioxide ligase subunit beta)PccbQ99MN93
Prostacyclin synthase (EC 5.3.99.4) (Prostaglandin I2 synthase)Ptgis Cyp8O350743
Proteasome inhibitor PI31 subunitPsmf1Q8BHL83
Proteasome subunit beta type-2 (EC 3.4.25.1) (Macropain subunit C7-I) (Multicatalytic endopeptidase complex subunit C7-I) (Proteasome component C7-I)Psmb2Q9R1P33
Proteasome subunit beta type-3 (EC 3.4.25.1) (Proteasome chain 13) (Proteasome component C10-II) (Proteasome theta chain)Psmb3Q9R1P13
Proteasome subunit beta type-7 (EC 3.4.25.1) (Macropain chain Z) (Multicatalytic endopeptidase complex chain Z) (Proteasome subunit Z)Psmb7 Mmc14P701953
Protein 1700029P11Rik (Uncharacterized protein)1700029P11RikQ9CQ683
Protein 2610015P09Rik2610015P09RikJ3QQ273
Protein 2610305D13Rik2610305D13RikA2A7993
Protein 2610524H06Rik (RIKEN cDNA 2610524H06) (Uncharacterized protein)2610524H06Rik H2-Eb1 mCG_68103Q9CZU93
Protein 2700097O09Rik (RIKEN cDNA 2700097O09) (Uncharacterized protein)2700097O09Rik mCG_21241Q6PGK33
Protein 4930430D24Rik (Uncharacterized protein)4930430D24RikQ3V0X03
Protein 4930474N05Rik (Uncharacterized protein)4930474N05RikQ8BVR53
Protein 4933422H20Rik (Uncharacterized protein)4933422H20RikQ3V0613
Protein AAR2 homolog (AAR2 splicing factor homolog)Aar2Q9D2V53
Protein AATF (Apoptosis-antagonizing transcription factor) (Rb-binding protein Che-1) (Traube protein)Aatf Che1 TrbQ9JKX43
Protein Abca17Abca17E9PX953
Protein AF067063 (Protein Gm21731) (Putative uncharacterized protein uniform group of 2-cell-stage gene family) (cDNA sequence AF067063)AF067063 Gm21731O706183
Protein ALEX (Alternative gene product encoded by XL-exon)Gnas Gnas1Q6R0H63
Protein Amn1Amn1B8JKV03
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