| Receptor-type tyrosine-protein phosphatase R (R-PTP-R) (EC 3.1.3.48) (Phosphotyrosine phosphatase 13) (Protein-tyrosine-phosphatase SL) | Ptprr Ptp13 | Q62132 | 3 |
| Regulating synaptic membrane exocytosis protein 2 (Rab-3-interacting molecule 2) (RIM 2) (Rab-3-interacting protein 2) | Rims2 Rab3ip2 Rim2 | Q9EQZ7 | 3 |
| Regulation of nuclear pre-mRNA domain-containing protein 2 | Rprd2 Kiaa0460 | Q6NXI6 | 3 |
| Regulator of G-protein signaling 10 (RGS10) | Rgs10 | Q9CQE5 | 3 |
| Regulator of G-protein signaling 9-binding protein (RGS9-anchoring protein) | Rgs9bp R9ap | Q148R9 | 3 |
| RELT-like protein 1 | Rell1 | Q8K2J7 | 3 |
| Replication factor C subunit 4 (Activator 1 subunit 4) | Rfc4 | Q99J62 | 3 |
| Replication protein A 14 kDa subunit (RP-A p14) (Replication factor A protein 3) (RF-A protein 3) | Rpa3 | Q9CQ71 | 3 |
| Reticulon-1 (Neuroendocrine-specific protein) | Rtn1 Nsp | Q8K0T0 | 3 |
| Retinoic acid receptor RXR-beta (MHC class I regulatory element-binding protein H-2RIIBP) (Nuclear receptor subfamily 2 group B member 2) (Retinoid X receptor beta) | Rxrb Nr2b2 | P28704 | 3 |
| Reversion-inducing cysteine-rich protein with Kazal motifs (mRECK) | Reck | Q9Z0J1 | 3 |
| Rho guanine nucleotide exchange factor 3 | Arhgef3 | Q91X46 | 3 |
| Rho-related BTB domain-containing protein 3 (EC 3.6.1.-) | Rhobtb3 Kiaa0878 | Q9CTN4 | 3 |
| Rho-related GTP-binding protein RhoG (Sid 10750) | Rhog Arhg Sid10750 | P84096 | 3 |
| Rhomboid domain-containing protein 2 (Rhomboid-like protein 7) | Rhbdd2 Rhbdl7 | Q8VEK2 | 3 |
| Riboflavin kinase (EC 2.7.1.26) (ATP:riboflavin 5'-phosphotransferase) (Flavokinase) (KOI-4) | Rfk | Q8CFV9 | 3 |
| Ribonuclease 3 (EC 3.1.26.3) (Protein Drosha) (Ribonuclease III) (RNase III) | Drosha Etohi2 Rn3 Rnasen | Q5HZJ0 | 3 |
| Ribonuclease P protein subunit p25-like protein (RNase P protein subunit-like p25) (Rpp25-like protein) | Rpp25l | Q99JH1 | 3 |
| Ribonucleoside-diphosphate reductase subunit M2 (EC 1.17.4.1) (Ribonucleotide reductase small chain) (Ribonucleotide reductase small subunit) | Rrm2 | P11157 | 3 |
| Ribosomal protein S6 kinase alpha-3 (S6K-alpha-3) (EC 2.7.11.1) (90 kDa ribosomal protein S6 kinase 3) (p90-RSK 3) (p90RSK3) (MAP kinase-activated protein kinase 1b) (MAPK-activated protein kinase 1b) (MAPKAP kinase 1b) (MAPKAPK-1b) (Ribosomal S6 kinase 2) (RSK-2) (pp90RSK2) | Rps6ka3 Mapkapk1b Rps6ka-rs1 Rsk2 | P18654 | 3 |
| Ribosome production factor 2 homolog (Brix domain-containing protein 1) (Ribosome biogenesis protein RPF2 homolog) | Rpf2 Bxdc1 MNCb-4285 | Q9JJ80 | 3 |
| Ribosyldihydronicotinamide dehydrogenase [quinone] (EC 1.10.99.2) (NRH dehydrogenase [quinone] 2) (NRH:quinone oxidoreductase 2) (Quinone reductase 2) (QR2) | Nqo2 Nmor2 | Q9JI75 | 3 |
| RIKEN cDNA 2610206B13, isoform CRA_b (RING finger protein 219) | Rnf219 2610206B13Rik mCG_121034 | G3X8V5 | 3 |
| RING finger protein 121 | Rnf121 | Q8R1Z9 | 3 |
| RING finger protein 183 | Rnf183 | Q8QZS5 | 3 |
| Ring finger protein 26 | Rnf26 | Q8BUH7 | 3 |
| RING1 and YY1-binding protein (Death effector domain-associated factor) (DED-associated factor) | Rybp Dedaf | Q8CCI5 | 3 |
| RISC-loading complex subunit TARBP2 (Protamine-1 RNA-binding protein) (PRM-1 RNA-binding protein) (TAR RNA-binding protein 2) | Tarbp2 Prbp | P97473 | 3 |
| RNA polymerase II-associated protein 1 | Rpap1 Kiaa1403 | Q80TE0 | 3 |
| RNA polymerase-associated protein CTR9 homolog (SH2 domain-binding protein 1) (Tetratricopeptide repeat-containing, SH2-binding phosphoprotein of 150 kDa) (TPR-containing, SH2-binding phosphoprotein of 150 kDa) (p150TSP) | Ctr9 Kiaa0155 Sh2bp1 | Q62018 | 3 |
| RNA-binding motif protein, Y chromosome, family 1 member A1 (RNA-binding motif protein 1) (Y chromosome RNA recognition motif 1) | Rbmy1a1 Rbm | O35698 | 3 |
| RNA-binding protein 14 (RNA-binding motif protein 14) | Rbm14 | Q8C2Q3 | 3 |
| RNA-binding protein 34 (RNA-binding motif protein 34) | Rbm34 D8Ertd233e | Q8C5L7 | 3 |
| RNA-binding protein 38 (RNA-binding motif protein 38) (RNA-binding region-containing protein 1) (ssDNA-binding protein SEB4) | Rbm38 Rnpc1 Seb4 Seb4l | Q62176 | 3 |
| RNA-binding protein 48 | Rbm48 | Q8K2X2 | 3 |
| RNA-binding protein 5 (Putative tumor suppressor LUCA15) (RNA-binding motif protein 5) | Rbm5 Luca15 | Q91YE7 | 3 |
| RNA-binding protein EWS | Ewsr1 Ews Ewsh | Q61545 | 3 |
| RNA-binding protein with multiple splicing (RBP-MS) (Heart and RRM expressed sequence) (Hermes) | Rbpms Hermes | Q9WVB0 | 3 |
| RNA-binding protein with serine-rich domain 1 | Rnps1 | Q99M28 | 3 |
| Roquin-1 (Roquin) (Protein Sanroque) (RING finger and C3H zinc finger protein 1) (RING finger and CCCH-type zinc finger domain-containing protein 1) | Rc3h1 Gm551 Kiaa2025 | Q4VGL6 | 3 |
| Roundabout homolog 1 | Robo1 Dutt1 | O89026 | 3 |
| RUN and SH3 domain-containing protein 1 | Rusc1 | Q8BG26 | 3 |
| RWD domain-containing protein 2B | Rwdd2b ORF5 | Q99M03 | 3 |
| RWD domain-containing protein 4 | Rwdd4 Rwdd4a | Q9CPR1 | 3 |
| Sal-like 1 (Drosophila) (Sal-like protein 1) | Sall1 | Q6P5E3 | 3 |
| Schlafen-like protein 1 | Slfnl1 | Q8BHW9 | 3 |
| Secernin-1 | Scrn1 Kiaa0193 | Q9CZC8 | 3 |
| Secreted frizzled-related protein 2 (sFRP-2) (Protein SDF5) (Secreted apoptosis-related protein 1) (SARP-1) | Sfrp2 Sarp1 Sdf5 | P97299 | 3 |
| Secretory carrier-associated membrane protein 2 (Secretory carrier membrane protein 2) | Scamp2 | Q9ERN0 | 3 |
| Selection and upkeep of intraepithelial T-cells protein 7 (Skint-7) | Skint7 | A7XV04 | 3 |
| Sentrin-specific protease 1 (EC 3.4.22.68) (SUMO-1 protease 2) (SuPr-2) (Sentrin/SUMO-specific protease SENP1) | Senp1 Supr2 | P59110 | 3 |
| Serglycin (Mastocytoma proteoglycan core protein) (Secretory granule proteoglycan core protein) (gp600) | Srgn Prg Prg1 | P13609 | 3 |
| Serine hydroxymethyltransferase (EC 2.1.2.1) | Shmt2 | Q3TFD0 | 3 |
| Serine incorporator 5 (Axotomy-induced glycoprotein 3) (AIGP-3) | Serinc5 Aigp3 | Q8BHJ6 | 3 |
| Serine protease 44 (EC 3.4.21.-) (Testis serine protease 4) (TESSP-4) (Testis-specific serine protease 4) | Prss44 Tessp4 | Q402U7 | 3 |
| Serine protease hepsin (EC 3.4.21.106) [Cleaved into: Serine protease hepsin non-catalytic chain; Serine protease hepsin catalytic chain] | Hpn | O35453 | 3 |
| Serine protease HTRA1 (EC 3.4.21.-) (High-temperature requirement A serine peptidase 1) (Serine protease 11) | Htra1 Htra Prss11 | Q9R118 | 3 |
| Serine protease HTRA2, mitochondrial (EC 3.4.21.108) (High temperature requirement protein A2) (HtrA2) (Omi stress-regulated endoprotease) (Serine protease 25) (Serine proteinase OMI) | Htra2 Omi Prss25 | Q9JIY5 | 3 |
| Serine/arginine repetitive matrix protein 2 | Srrm2 Kiaa0324 | Q8BTI8 | 3 |
| Serine/Arginine-related protein 53 (SRrp53) (Arginine/serine-rich coiled-coil protein 1) | Rsrc1 Srrp53 | Q9DBU6 | 3 |
| Serine/arginine-rich-splicing factor 4 (Splicing factor, arginine/serine-rich 4 (SRp75)) | Srsf4 Sfrs4 mCG_16265 | Q542V3 | 3 |
| Serine/threonine-protein kinase 19 (EC 2.7.11.1) (Protein RP1) | Stk19 Rp1 | Q9JHN8 | 3 |
| Serine/threonine-protein kinase B-raf (EC 2.7.11.1) (Proto-oncogene B-Raf) | Braf B-raf | P28028 | 3 |
| Serine/threonine-protein kinase DCLK3 (EC 2.7.11.1) (CLICK-I and II-related) (CLr) (Doublecortin-like and CAM kinase-like 3) (Doublecortin-like kinase 3) | Dclk3 Dcamkl3 | Q8BWQ5 | 3 |
| Serine/threonine-protein kinase Nek3 (EC 2.7.11.1) (Never in mitosis A-related kinase 3) (NimA-related protein kinase 3) | Nek3 | Q9R0A5 | 3 |
| Serine/threonine-protein kinase Nek8 (EC 2.7.11.1) (Never in mitosis A-related kinase 8) (NimA-related protein kinase 8) | Nek8 Jck | Q91ZR4 | 3 |
| Serine/threonine-protein kinase RIO2 (EC 2.7.11.1) (RIO kinase 2) | Riok2 | Q9CQS5 | 3 |
| Serine/threonine-protein kinase SIK3 (EC 2.7.11.1) (Salt-inducible kinase 3) (SIK-3) (Serine/threonine-protein kinase QSK) | Sik3 Kiaa0999 Qsk | Q6P4S6 | 3 |
| Serine/threonine-protein kinase TAO1 (EC 2.7.11.1) (Thousand and one amino acid protein 1) | Taok1 Kiaa1361 | Q5F2E8 | 3 |
| Serine/threonine-protein kinase TAO3 (EC 2.7.11.1) (Thousand and one amino acid protein 3) | Taok3 | Q8BYC6 | 3 |
| Serine/threonine-protein kinase tousled-like 2 (EC 2.7.11.1) (PKU-alpha) (Tousled-like kinase 2) | Tlk2 Tlk | O55047 | 3 |
| Serine/threonine-protein phosphatase 1 regulatory subunit 10 (MHC class I region proline-rich protein CAT53) | Ppp1r10 Cat53 Pnuts | Q80W00 | 3 |
| Serine/threonine-protein phosphatase 4 regulatory subunit 3A (SMEK homolog 1) | Smek1 Kiaa2010 Pp4r3a Ppp4r3a | Q6P2K6 | 3 |
| Serine/threonine-protein phosphatase PGAM5, mitochondrial (EC 3.1.3.16) (Phosphoglycerate mutase family member 5) | Pgam5 | Q8BX10 | 3 |
| Serologically defined colon cancer antigen 8 homolog (Centrosomal colon cancer autoantigen protein) (mCCCAP) | Sdccag8 Cccap | Q80UF4 | 3 |
| Serum deprivation-response protein (Cavin-2) (Phosphatidylserine-binding protein) | Sdpr Sdr | Q63918 | 3 |
| SET and MYND domain-containing protein 5 (EC 2.1.1.-) (Protein NN8-4AG) (Retinoic acid-induced protein 15) | Smyd5 Rai15 | Q3TYX3 | 3 |
| SH2 domain-containing adapter protein D | Shd | O88834 | 3 |
| SH3 and multiple ankyrin repeat domains protein 3 (Shank3) (Proline-rich synapse-associated protein 2) (ProSAP2) (SPANK-2) | Shank3 Kiaa1650 | Q4ACU6 | 3 |
| SH3 domain-containing protein 21 | Sh3d21 | Q7TSG5 | 3 |
| Sharpin (Shank-associated RH domain-interacting protein) (Shank-interacting protein-like 1) (mSIPL1) | Sharpin Cpdm Sipl1 | Q91WA6 | 3 |
| SHC-transforming protein 3 (Neuronal Shc) (N-Shc) (SHC-transforming protein C) (Src homology 2 domain-containing-transforming protein C3) (SH2 domain protein C3) | Shc3 Nshc ShcC | Q61120 | 3 |
| Short transient receptor potential channel 4-associated protein (Trp4-associated protein) (Trpc4-associated protein) (Protein TAP1) (Rabex-5/Rin2-interacting protein) (TNF-receptor ubiquitous scaffolding/signaling protein) (Protein TRUSS) | Trpc4ap Trrp4ap | Q9JLV2 | 3 |
| Signal peptide, CUB and EGF-like domain-containing protein 2 | Scube2 | D3YVM9 | 3 |
| Signal recognition particle 19 kDa protein (Signal recognition particle 19, isoform CRA_a) (Srp19 protein) | Srp19 mCG_121501 | Q9D104 | 3 |
| Signal recognition particle receptor subunit alpha (SR-alpha) (Docking protein alpha) (DP-alpha) | Srpr | Q9DBG7 | 3 |
| Signal recognition particle subunit SRP72 | Srp72 | F8VQC1 | 3 |
| Signaling threshold-regulating transmembrane adapter 1 (SHP2-interacting transmembrane adapter protein) (Suppression-inducing transmembrane adapter 1) | Sit1 Sit | Q8C503 | 3 |
| Single-stranded DNA cytosine deaminase (EC 3.5.4.38) (Activation-induced cytidine deaminase) (Cytidine aminohydrolase) | Aicda Aid | Q9WVE0 | 3 |
| SLIT and NTRK-like protein 1 | Slitrk1 Sltk1 | Q810C1 | 3 |
| Small nuclear ribonucleoprotein Sm D3 (Sm-D3) (snRNP core protein D3) | Snrpd3 | P62320 | 3 |
| Small ubiquitin-related modifier 2 (SUMO-2) (SMT3 homolog 2) (Sentrin-2) (Ubiquitin-like protein SMT3A) (Smt3A) | Sumo2 Smt3a Smt3h2 | P61957 | 3 |
| Sodium-coupled neutral amino acid transporter 3 (N-system amino acid transporter 1) (Na(+)-coupled neutral amino acid transporter 3) (Solute carrier family 38 member 3) (mNAT) (System N amino acid transporter 1) | Slc38a3 Sn1 Snat3 | Q9DCP2 | 3 |
| Sodium-dependent neutral amino acid transporter B(0)AT2 (Sodium- and chloride-dependent neurotransmitter transporter NTT73) (Solute carrier family 6 member 15) (Transporter v7-3) | Slc6a15 B0at2 Ntt73 | Q8BG16 | 3 |
| Sodium-dependent neutral amino acid transporter SLC6A17 (Sodium-dependent neurotransmitter transporter NTT4) (Solute carrier family 6 member 17) | Slc6a17 Ntt4 | Q8BJI1 | 3 |
| Sodium-dependent serotonin transporter (5HT transporter) (5HTT) (Solute carrier family 6 member 4) | Slc6a4 Htt Sert | Q60857 | 3 |
| Sodium/glucose cotransporter 2 (Na(+)/glucose cotransporter 2) (Low affinity sodium-glucose cotransporter) (Solute carrier family 5 member 2) | Slc5a2 Sglt2 | Q923I7 | 3 |
| Soluble scavenger receptor cysteine-rich domain-containing protein SSC5D (Scavenger receptor cysteine-rich domain-containing protein LOC284297 homolog) | Ssc5d S5D-SRCRB | Q8BV57 | 3 |
| Solute carrier family 13 member 3 (Na(+)/dicarboxylate cotransporter 3) (NaDC-3) (mNaDC3) (Sodium-dependent high-affinity dicarboxylate transporter 2) | Slc13a3 Nadc3 Sdct2 | Q91Y63 | 3 |
| Solute carrier family 25 member 40 | Slc25a40 | Q8BGP6 | 3 |