EVpedia provide top 100+ EV markers, selected according to their identification number.
Based on EV proteomes, we defined the identification number of protein A as the number of datasets which contain protein A.
Therefore, proteins with higher identification numbers were more conserved.

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Protein name Gene symbol UniProt accession Identification number
Transient receptor potential cation channel subfamily M member 7 (EC 2.7.11.1) (Channel-kinase 1) (Long transient receptor potential channel 7) (LTrpC-7) (LTrpC7) (Transient receptor potential-phospholipase C-interacting kinase) (TRP-PLIK)Trpm7 Chak Ltrpc7Q923J13
Transitional endoplasmic reticulum ATPase (TER ATPase) (EC 3.6.4.6) (15S Mg(2+)-ATPase p97 subunit) (Valosin-containing protein) (VCP)VcpQ018533
Transmembrane 7 superfamily member 3 (NARP1)Tm7sf3Q9CRG13
Transmembrane channel-like protein 1 (Beethoven protein) (Deafness protein) (Transmembrane cochlear-expressed protein 1)Tmc1 Bth dnQ8R4P53
Transmembrane glycoprotein NMB (DC-HIL) (Dendritic cell-associated transmembrane protein) (Osteoactivin)Gpnmb Dchil Hgfin NmbQ99P913
Transmembrane protein 106BTmem106bQ80X713
Transmembrane protein 134Tmem134Q8R0J43
Transmembrane protein 161BTmem161bQ8C2L63
Transmembrane protein 189Tmem189Q99LQ73
Transmembrane protein 206Tmem206Q9D7713
Transmembrane protein 239Tmem239Q9DA473
Transmembrane protein 242Tmem242Q8VCR33
Transportin-3Tnpo3Q6P2B13
Treacle protein (Treacher Collins syndrome protein homolog)Tcof1O087843
Trimethylguanosine synthase (EC 2.1.1.-) (Nuclear receptor coactivator 6-interacting protein) (PRIP-interacting protein with methyltransferase motif) (PIMT) (PIPMT)Tgs1 Ncoa6ip PimtQ923W13
Trinucleotide repeat-containing gene 6C proteinTnrc6c Kiaa1582Q3UHC03
Tripartite motif-containing protein 12ATrim12a Trim12Q99PQ13
Tripartite motif-containing protein 2 (EC 6.3.2.-) (E3 ubiquitin-protein ligase TRIM2) (Neural activity-related RING finger protein)Trim2 Kiaa0517 NarfQ9ESN63
Tripartite motif-containing protein 35 (Hemopoietic lineage switch protein 5) (Macrophage-derived apoptosis-inducing RBCC protein) (Protein MAIR) (Protein Nc8)Trim35 Hls5 Kiaa1098 MairQ8C0063
Tripeptidyl-peptidase 2 (TPP-2) (EC 3.4.14.10) (Tripeptidyl aminopeptidase) (Tripeptidyl-peptidase II) (TPP-II)Tpp2Q645143
Triple QxxK/R motif-containing protein (Triple repetitive-sequence of QXXK/R protein homolog)Triqk Gm11818B2B9E13
tRNA (uracil(54)-C(5))-methyltransferase homolog (EC 2.1.1.35) (TRM2 homolog)Trmt2bQ8BQJ63
tRNA methyltransferase 10 homolog A (EC 2.1.1.-) (RNA (guanine-9-)-methyltransferase domain-containing protein 2)Trmt10a Rg9mtd2Q8C1Z83
tRNA methyltransferase 112 homolog (TRM112-like protein)Trmt112Q9DCG93
tRNA pseudouridine(38/39) synthase (EC 5.4.99.45) (tRNA pseudouridine synthase 3) (tRNA pseudouridylate synthase 3) (tRNA-uridine isomerase 3)Pus3Q9JI383
tRNA-dihydrouridine(16/17) synthase [NAD(P)(+)]-like (EC 1.3.1.-) (tRNA-dihydrouridine synthase 1-like)Dus1lQ8C2P33
tRNA-splicing endonuclease subunit Sen15 (tRNA-intron endonuclease Sen15)Tsen15 Sen15Q8R3W53
Tropomyosin alpha-1 chain (Alpha-tropomyosin) (Tropomyosin-1)Tpm1 Tpm-1 TpmaP587713
Truncated Wilms' tumor proteinWt1Q199A73
Tryptophan 5-hydroxylase 1 (EC 1.14.16.4) (Tryptophan 5-monooxygenase 1)Tph1 TphP175323
Tubulin gamma-2 chain (Gamma-2-tubulin)Tubg2Q8VCK33
Tubulin--tyrosine ligase (TTL) (EC 6.3.2.25)TtlP385853
Tumor necrosis factor receptor superfamily member 13C (B-cell maturation defect) (B-cell-activating factor receptor) (BAFF receptor) (BAFF-R) (BLyS receptor 3) (CD antigen CD268)Tnfrsf13c Baffr Bcmd Br3Q9D8D03
Tumor necrosis factor receptor superfamily member 19LRelt Tnfrsf19lQ8BX433
Tumor necrosis factor receptor superfamily member 3 (Lymphotoxin-beta receptor)Ltbr Tnfcr Tnfrsf3P502843
Twinfilin-1 (Protein A6)Twf1 Ptk9Q91YR13
Twinfilin-2 (A6-related protein) (mA6RP) (Twinfilin-1-like protein)Twf2 Ptk9lQ9Z0P53
Tyrosine-protein kinase (EC 2.7.10.2)Tyk2E9QJS13
Tyrosine-protein kinase RYK (EC 2.7.10.1) (Kinase VIK) (Met-related kinase) (NYK-R)Ryk MrkQ018873
Tyrosine-protein phosphatase non-receptor type 22 (EC 3.1.3.48) (Hematopoietic cell protein-tyrosine phosphatase 70Z-PEP) (PEST-domain phosphatase) (PEP)Ptpn22 Ptpn8P293523
U11/U12 small nuclear ribonucleoprotein 25 kDa protein (U11/U12 snRNP 25 kDa protein)Snrnp25Q8VIK13
U2 small nuclear ribonucleoprotein B'' (U2 snRNP B'')Snrpb2Q9CQI73
U4/U6.U5 small nuclear ribonucleoprotein 27 kDa protein (U4/U6.U5 snRNP 27 kDa protein) (U4/U6.U5-27K) (U4/U6.U5 tri-snRNP-associated protein 3)Snrnp27Q8K1943
U5 small nuclear ribonucleoprotein 40 kDa protein (U5 snRNP 40 kDa protein) (WD repeat-containing protein 57)Snrnp40 Wdr57Q6PE013
U6 snRNA-associated Sm-like protein LSm7Lsm7Q9CQQ83
U8 snoRNA-decapping enzyme (EC 3.6.1.62) (IDP phosphatase) (IDPase) (EC 3.6.1.-) (Inosine diphosphate phosphatase) (Nucleoside diphosphate-linked moiety X motif 16) (Nudix motif 16) (m7GpppN-mRNA hydrolase)Nudt16Q6P3D03
Ubiquinone biosynthesis protein COQ7 homolog (Coenzyme Q biosynthesis protein 7 homolog) (Timing protein clk-1 homolog)Coq7P974783
Ubiquitin carboxyl-terminal hydrolase 17-like protein A (USP17-A) (EC 3.4.19.12) (Deubiquitinating enzyme 1) (Ubiquitin carboxyl-terminal hydrolase DUB-1) (Ubiquitin thioesterase DUB-1) (Ubiquitin-specific-processing protease DUB-1)Usp17la Dub-1 Dub1Q610683
Ubiquitin carboxyl-terminal hydrolase BAP1 (EC 3.4.19.12) (BRCA1-associated protein 1) (Ubiquitin C-terminal hydrolase X4) (UCH-X4)Bap1 Kiaa0272Q99PU73
Ubiquitin-40S ribosomal protein S27a (Ubiquitin carboxyl extension protein 80) [Cleaved into: Ubiquitin; 40S ribosomal protein S27a]Rps27a Uba80 Ubcep1P629833
Ubiquitin-associated domain-containing protein 2 (UBA domain-containing protein 2) (Phosphoglycerate dehydrogenase-like protein 1)Ubac2 Phgdhl1Q8R1K13
Ubiquitin-conjugating enzyme E2 E1 (EC 6.3.2.19) (UbcM3) (Ubiquitin carrier protein E1) (Ubiquitin-protein ligase E1)Ube2e1 Ubce5 Ubcm3P524823
Ubiquitin-conjugating enzyme E2 H (EC 6.3.2.19) (UBCH2) (Ubiquitin carrier protein H) (Ubiquitin-conjugating enzyme E2-20K) (Ubiquitin-protein ligase H)Ube2hP622573
Ubiquitin-conjugating enzyme E2 R1 (EC 6.3.2.19) (Ubiquitin-conjugating enzyme E2-32 kDa complementing) (Ubiquitin-conjugating enzyme E2-CDC34) (Ubiquitin-protein ligase R1)Cdc34 Ubch3 Ube2r1Q8CFI23
Ubiquitin-conjugating enzyme E2 variant 1 (UEV-1) (CROC-1)Ube2v1 Croc1Q9CZY33
Ubiquitin-fold modifier 1Ufm1P619613
Ubiquitin-like protein ATG12 (Autophagy-related protein 12) (APG12-like)Atg12 Apg12 Apg12lQ9CQY13
UBX domain-containing protein 4 (Erasin) (UBX domain-containing protein 2)Ubxn4 Ubxd2 Ubxdc1Q8VCH83
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3 (BGnT-3) (Beta-1,3-Gn-T3) (Beta-1,3-N-acetylglucosaminyltransferase 3) (Beta3Gn-T3) (EC 2.4.1.-) (Core 1 extending beta-1,3-N-acetylglucosaminyltransferase) (Core1-beta3GlcNAcT)B3gnt3Q5JCS93
UDP-glucuronic acid decarboxylase 1 (EC 4.1.1.35) (UDP-glucuronate decarboxylase 1) (UGD) (UXS-1)Uxs1Q91XL33
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 20Galntl6E5D8G13
UDP-N-acetylglucosamine transporter (Golgi UDP-GlcNAc transporter) (Solute carrier family 35 member A3)Slc35a3Q8R1T43
Uncharacterized aarF domain-containing protein kinase 2 (EC 2.7.11.-)Adck2Q6NSR33
Uncharacterized protein C11orf84 homolog0Q05AH63
Uncharacterized protein C14orf28 homologGm527Q4KL133
Uncharacterized protein C15orf62 homolog, mitochondrialGm14137Q8CE973
Uncharacterized protein C16orf74 homolog0Q8K1L63
Uncharacterized protein C17orf59 homolog0Q9D6W83
Uncharacterized protein C17orf85 homolog0Q8BZR93
Uncharacterized protein C19orf43 homolog0Q9D7353
Uncharacterized protein C1orf146 homolog0Q3KQP73
Uncharacterized protein C1orf194 homolog0Q9DAD03
Uncharacterized protein C1orf51 homologGm129Q3TQ033
Uncharacterized protein C2orf78 homologGm5592Q3V0A63
Uncharacterized protein C3orf20 homolog0Q8CDN13
Uncharacterized protein C3orf22 homolog0Q8C5S33
Uncharacterized protein C7orf63 homolog0Q8BH533
Uncharacterized protein CXorf65 homologGm614Q3V2K13
Uncharacterized protein KIAA0556Kiaa0556Q8C7533
Uncharacterized protein KIAA1841Kiaa1841Q68FF03
Unconventional myosin-Ib (MIH-L) (Myosin I alpha) (MMI-alpha) (MMIa)Myo1bP467353
Unconventional prefoldin RPB5 interactor (Protein NNX3) (Protein phosphatase 1 regulatory subunit 19) (RNA polymerase II subunit 5-mediating protein) (RPB5-mediating protein)Uri1 Nnx3 Ppp1r19 Rmp UriQ3TLD53
UPF0235 protein C15orf40 homolog0Q9CRC33
UPF0369 protein C6orf57 homolog0Q8BTE03
UPF0420 protein C16orf58 homolog0Q91W343
UPF0524 protein C3orf70 homolog0Q6GQU03
UPF0562 protein C7orf55 homolog0Q9CR133
UPF0568 protein C14orf166 homolog0Q9CQE83
UPF0574 protein C9orf169 homolog0Q9D1E43
UPF0668 protein C10orf76 homolog0Q6PD193
UPF0687 protein C20orf27 homolog0Q9D1K73
UPF0693 protein C10orf32 homolog0Q9CRC63
UTP--glucose-1-phosphate uridylyltransferase (EC 2.7.7.9) (UDP-glucose pyrophosphorylase) (UDPGP) (UGPase)Ugp2Q91ZJ53
V-type proton ATPase 116 kDa subunit a isoform 2 (V-ATPase 116 kDa isoform a2) (Immune suppressor factor J6B7) (ISF) (Lysosomal H(+)-transporting ATPase V0 subunit a2) (ShIF) (Vacuolar proton translocating ATPase 116 kDa subunit a isoform 2)Atp6v0a2 Atp6n1b Tj6P159203
V-type proton ATPase subunit d 2 (V-ATPase subunit d 2) (Osteoclast-specific vacuolar ATP synthase) (Vacuolar proton pump subunit d 2)Atp6v0d2Q80SY33
Vacuolar ATPase assembly integral membrane protein VMA21Vma21Q78T543
Vacuolar protein sorting-associated protein 29 (EC 3.1.3.3) (Vesicle protein sorting 29)Vps29Q9QZ883
Vacuolar protein sorting-associated protein 53 homologVps53Q8CCB43
Vacuolar protein sorting-associated protein 54 (Tumor antigen SLP-8p homolog)Vps54Q5SPW03
Valine--tRNA ligase, mitochondrial (EC 6.1.1.9) (Valyl-tRNA synthetase) (ValRS)Vars2 Kiaa1885 Vars2lQ3U2A83
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