EVpedia provide top 100+ EV markers, selected according to their identification number.
Based on EV proteomes, we defined the identification number of protein A as the number of datasets which contain protein A.
Therefore, proteins with higher identification numbers were more conserved.

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Protein name Gene symbol UniProt accession Identification number
ATP-dependent RNA helicase DDX24 (EC 3.6.4.13) (DEAD box protein 24)Ddx24Q9ESV02
ATP-dependent zinc metalloprotease YME1L1 (EC 3.4.24.-) (ATP-dependent metalloprotease FtsH1) (YME1-like protein 1)Yme1l1O889672
ATPase family AAA domain-containing protein 3 (AAA-ATPase TOB3)Atad3 Atad3a Kiaa1273Q925I12
ATPase WRNIP1 (EC 3.6.1.3) (Werner helicase-interacting protein 1)Wrnip1 WhipQ91XU02
Atrial natriuretic peptide receptor 2 (EC 4.6.1.2) (Atrial natriuretic peptide receptor type B) (ANP-B) (ANPR-B) (NPR-B) (Guanylate cyclase B) (GC-B)Npr2Q6VVW52
Atypical chemokine receptor 4 (C-C chemokine receptor type 11) (C-C CKR-11) (CC-CKR-11) (CCR-11) (CC chemokine receptor-like 1) (CCRL1) (CCX CKR)Ackr4 Ccr11 Ccrl1Q924I32
Aurora kinase A and ninein-interacting proteinAunipE9Q6Z52
Aurora kinase A-interacting protein (AURKA-interacting protein) (28S ribosomal protein S38, mitochondrial) (MRP-S38)Aurkaip1 Aip Akip Mrps38Q9DCJ72
Autophagy protein 5 (APG5-like)Atg5 Apg5lQ99J832
Autophagy-related protein 16-1 (APG16-like 1)Atg16l1 Apg16lQ8C0J22
Auts2 protein (Fragment)Auts2Q6PED72
Axin interactor, dorsalization-associated protein (Axin interaction partner and dorsalization antagonist)AidaQ8C4Q62
Axin-1 (Axis inhibition protein 1) (Protein Fused)Axin1 Axin FuO356252
B-cell CLL/lymphoma 7 protein family member ABcl7aQ9CXE22
B-cell lymphoma 3 protein homolog (BCL-3)Bcl3Q9Z2F62
B-cell lymphoma/leukemia 10 (B-cell CLL/lymphoma 10) (Bcl-10) (CARD-containing molecule enhancing NF-kappa-B) (CARD-like apoptotic protein) (mCLAP) (CED-3/ICH-1 prodomain homologous E10-like regulator) (mCIPER) (Cellular homolog of vCARMEN) (cCARMEN) (Cellular-E10) (c-E10) (Mammalian CARD-containing adapter molecule E10) (mE10)Bcl10 Ciper ClapQ9Z0H72
B-lymphocyte antigen CD20 (B-cell differentiation antigen Ly-44) (Lymphocyte antigen 44) (Membrane-spanning 4-domains subfamily A member 1) (CD antigen CD20)Ms4a1 Cd20 Ly-44 Ms4a2P194372
Bactericidal permeability-increasing protein (BPI)BpiQ67E052
BAH and coiled-coil domain-containing protein 1Bahcc1 Kiaa1447Q3UHR02
Band 4.1-like protein 2 (Generally expressed protein 4.1) (4.1G)Epb41l2 Epb4.1l2O703182
Band 4.1-like protein 4B (Protein EHM2)Epb41l4b Ehm2 Epb4.1l4bQ9JMC82
Bardet-Biedl syndrome 7 protein homolog (BBS2-like protein 1)Bbs7 Bbs2l1Q8K2G42
Basic leucine zipper transcriptional factor ATF-like 2 (B-ATF-2)Batf2Q8R1H82
Bax inhibitor 1 (BI-1) (Testis-enhanced gene transcript protein) (Transmembrane BAX inhibitor motif-containing protein 6)Tmbim6 TegtQ9D2C72
BC049762 protein (Protein BC049762)BC049762Q8C6012
BC060267 proteinEfcab12 BC060267I6L9E62
BET1 homolog (mBET1) (Golgi vesicular membrane-trafficking protein p18)Bet1O356232
Beta-1,3-N-acetylglucosaminyltransferase manic fringe (EC 2.4.1.222) (O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase)MfngO090082
Beta-adducin (Add97) (Erythrocyte adducin subunit beta)Add2Q9QYB82
Beta-catenin-like protein 1 (Nuclear-associated protein) (NAP)Ctnnbl1Q9CWL82
Beta-centractin (Actin-related protein 1B) (ARP1B)Actr1bQ8R5C52
Beta-defensin 41 (BD-41) (mBD-41) (Defensin, beta 41)Defb41 Defb16Q8C1G42
Beta-defensin 43 (BD-43) (mBD-43) (Defensin, beta 43)Defb43Q30KM92
Beta-galactosidase (EC 3.2.1.23) (Acid beta-galactosidase) (Lactase)Glb1 Bgl Glb-1P237802
Bifunctional lysine-specific demethylase and histidyl-hydroxylase NO66 (EC 1.14.11.-) (EC 1.14.11.27) (Histone lysine demethylase NO66)No66 Mapjd MNCb-7109Q9JJF32
Bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase (UDP-GlcNAc-2-epimerase/ManAc kinase) [Includes: UDP-N-acetylglucosamine 2-epimerase (hydrolyzing) (EC 3.2.1.183) (UDP-GlcNAc-2-epimerase) (Uridine diphosphate-N-acetylglucosamine-2-epimerase); N-acetylmannosamine kinase (EC 2.7.1.60) (ManAc kinase)]Gne Glcne Uae1Q91WG82
Biogenesis of lysosome-related organelles complex 1 subunit 4 (BLOC-1 subunit 4) (Protein cappuccino homolog)Bloc1s4 CnoQ8VED22
Bis(5'-adenosyl)-triphosphatase enpp4 (EC 3.6.1.29) (AP3A hydrolase) (AP3Aase) (Ectonucleotide pyrophosphatase/phosphodiesterase family member 4) (E-NPP 4) (NPP-4)Enpp4 Kiaa0879Q8BTJ42
Bis(5'-nucleosyl)-tetraphosphatase [asymmetrical] (EC 3.6.1.17) (Diadenosine 5',5'''-P1,P4-tetraphosphate asymmetrical hydrolase) (Ap4A hydrolase) (Ap4Aase) (Diadenosine tetraphosphatase) (Nucleoside diphosphate-linked moiety X motif 2) (Nudix motif 2)Nudt2 Apah1P563802
Bladder cancer-associated protein (Bladder cancer 10 kDa protein) (Bc10)Blcap Bc10P629512
BolA-like protein 2Bola2Q8BGS22
BolA-like protein 3Bola3Q8CEI12
Bone marrow proteoglycan (BMPG) (Proteoglycan 2) [Cleaved into: Eosinophil granule major basic protein (EMBP) (MBP)]Prg2 Mbp-1Q618782
Bone morphogenetic protein 15 (BMP-15) (Growth/differentiation factor 9B) (GDF-9B)Bmp15 Gdf9bQ9Z0L42
Bone morphogenetic protein 8A (BMP-8A) (Osteogenic protein 2) (OP-2)Bmp8a Bmp-8 Bmp8P348212
Bone morphogenetic protein receptor type-2 (BMP type-2 receptor) (BMPR-2) (EC 2.7.11.30) (BRK-3) (Bone morphogenetic protein receptor type II) (BMP type II receptor) (BMPR-II)Bmpr2O356072
BPI fold-containing family B member 1 (Long palate, lung and nasal epithelium carcinoma-associated protein 1)Bpifb1 Lplunc1Q611142
Brain protein I3Bri3P286622
Brain-specific serine protease 4 (BSSP-4) (EC 3.4.21.-) (Serine protease 22) (Serine protease 26) (Tryptase epsilon)Prss22 Bssp4 Prss26Q9ER102
BRCA1-associated ATM activator 1 (BRCA1-associated protein required for ATM activation protein 1)Brat1 Baat1Q8C3R12
Breakpoint cluster region protein (EC 2.7.11.1)Bcr Kiaa3017Q6PAJ12
Breast cancer anti-estrogen resistance protein 3 (p130Cas-binding protein AND-34)Bcar3 And34Q9QZK22
Breast cancer type 1 susceptibility protein homolog (EC 6.3.2.-)Brca1P487542
Brefeldin A-inhibited guanine nucleotide-exchange protein 1 (BIG1) (Brefeldin A-inhibited GEP 1) (ADP-ribosylation factor guanine nucleotide-exchange factor 1)Arfgef1G3X9K32
BRISC and BRCA1-A complex member 1 (Mediator of RAP80 interactions and targeting subunit of 40 kDa) (New component of the BRCA1-A complex)Babam1 Merit40 Nba1Q3UI432
Bromodomain adjacent to zinc finger domain protein 1ABaz1aG3UWZ02
Bromodomain and WD repeat-containing protein 1 (WD repeat-containing protein 9)Brwd1 Wdr9Q921C32
Bromodomain-containing protein 7 (75 kDa bromodomain protein)Brd7 Bp75O886652
BTB/POZ domain-containing protein KCTD1Kctd1Q5M9562
BTB/POZ domain-containing protein KCTD15 (Potassium channel tetramerization domain-containing protein 15)Kctd15Q8K0E12
BTB/POZ domain-containing protein KCTD19Kctd19Q562E22
BTB/POZ domain-containing protein KCTD20Kctd20Q8CDD82
C-C chemokine receptor type 2 (C-C CKR-2) (CC-CKR-2) (CCR-2) (CCR2) (JE/FIC receptor) (MCP-1 receptor) (CD antigen CD192)Ccr2 Cmkbr2P516832
C-C motif chemokine 5 (MuRantes) (SIS-delta) (Small-inducible cytokine A5) (T-cell-specific protein RANTES)Ccl5 Scya5P308822
C-C motif chemokine 7 (Intercrine/chemokine MARC) (Monocyte chemoattractant protein 3) (Monocyte chemotactic protein 3) (MCP-3) (Protein FIC) (Small-inducible cytokine A7)Ccl7 Fic Mcp3 Scya7Q033662
C-terminal-binding protein 1 (CtBP1) (EC 1.1.1.-)Ctbp1O887122
C-type lectin domain family 1 member AClec1aQ8BWY22
C-type lectin domain family 1 member B (C-type lectin-like receptor 2) (CLEC-2)Clec1b Clec2Q9JL992
C-type lectin domain family 2 member G (DDV10) (Osteoclast inhibitory lectin-related protein 1) (Ocil-related protein 1)Clec2g Clec2f Ddv10 Ocilrp1Q9D6762
C-type lectin domain family 7 member A (Beta-glucan receptor) (C-type lectin superfamily member 12) (Dendritic cell-associated C-type lectin 1) (DC-associated C-type lectin 1) (Dectin-1)Clec7a Bgr Clecsf12 Dectin1Q6QLQ42
C5a anaphylatoxin chemotactic receptor 2 (Complement component 5a receptor 2) (G-protein coupled receptor 77)C5ar2 C5l2 Gpr77Q8BW932
CactinCactinQ9CS002
Cadherin-2 (Neural cadherin) (N-cadherin) (CD antigen CD325)Cdh2P151162
Cadherin-24Cdh24Q6PFX62
Cadherin-8Cdh8P972912
Cadherin-like protein 26Cdh26 Gm1010P598622
Calcium channel flower homolog (Calcium channel flower domain-containing protein 1)Cacfd1Q8BG212
Calcium-activated chloride channel regulator 4Clca4E9PUL32
Calcium-binding and coiled-coil domain-containing protein 1 (Coiled-coil coactivator protein)Calcoco1 CocoA Kiaa1536Q8CGU12
Calcium-binding mitochondrial carrier protein SCaMC-1 (Small calcium-binding mitochondrial carrier protein 1) (Solute carrier family 25 member 24)Slc25a24 Scamc1Q8BMD82
Calcium-transporting ATPase type 2C member 1 (ATPase 2C1) (EC 3.6.3.8) (ATP-dependent Ca(2+) pump PMR1)Atp2c1 Pmr1Q80XR22
Calcyclin-binding protein (CacyBP) (Siah-interacting protein)Cacybp SipQ9CXW32
Calmodulin-regulated spectrin-associated protein 1Camsap1A2AHC32
Calponin-3 (Calponin, acidic isoform)Cnn3Q9DAW92
Calreticulin (CRP55) (Calregulin) (Endoplasmic reticulum resident protein 60) (ERp60) (HACBP)CalrP142112
cAMP-responsive element-binding protein-like 2Crebl2Q32M002
cAMP-specific 3',5'-cyclic phosphodiesterase 4A (EC 3.1.4.17)Pde4aO890842
CAMPATH-1 antigen (Lymphocyte differentiation antigen B7) (CD antigen CD52)Cd52 Cdw52 Mb7Q643892
Carbohydrate sulfotransferase 12 (EC 2.8.2.5) (Chondroitin 4-O-sulfotransferase 2) (Chondroitin 4-sulfotransferase 2) (C4ST-2) (C4ST2)Chst12Q99LL32
Carbohydrate sulfotransferase 3 (EC 2.8.2.17) (Chondroitin 6-O-sulfotransferase 1) (C6ST-1) (Galactose/N-acetylglucosamine/N-acetylglucosamine 6-O-sulfotransferase 0) (GST-0)Chst3 C6st Gst0O881992
Carbohydrate sulfotransferase 8 (EC 2.8.2.-) (GalNAc-4-O-sulfotransferase 1) (GalNAc-4-ST1) (GalNAc4ST-1) (N-acetylgalactosamine-4-O-sulfotransferase 1)Chst8Q8BQ862
Carbonic anhydrase 3 (EC 4.2.1.1) (Carbonate dehydratase III) (Carbonic anhydrase III) (CA-III)Ca3 Car3P160152
Carbonic anhydrase 9 (EC 4.2.1.1) (Carbonate dehydratase IX) (Carbonic anhydrase IX) (CA-IX) (CAIX) (Membrane antigen MN homolog)Ca9 Car9Q8VHB52
Carbonic anhydrase-related protein (CARP) (Carbonic anhydrase VIII) (CA-VIII)Ca8 Cals Cals1 Car8 CarpP286512
Carboxypeptidase B2 (EC 3.4.17.20) (Carboxypeptidase R) (CPR) (Carboxypeptidase U) (CPU) (Thrombin-activable fibrinolysis inhibitor) (TAFI)Cpb2 TafiQ9JHH62
Carboxypeptidase E (CPE) (EC 3.4.17.10) (Carboxypeptidase H) (CPH) (Enkephalin convertase) (Prohormone-processing carboxypeptidase)CpeQ004932
Carboxypeptidase Q (EC 3.4.17.-) (Hematopoietic lineage switch 2) (Plasma glutamate carboxypeptidase)Cpq Hls2 PgcpQ9WVJ32
Carnitine O-acetyltransferase (Carnitine acetylase) (EC 2.3.1.7) (Carnitine acetyltransferase) (CAT) (CrAT)CratP479342
Carnitine O-palmitoyltransferase 1, muscle isoform (CPT1-M) (EC 2.3.1.21) (Carnitine O-palmitoyltransferase I, muscle isoform) (CPT I) (CPTI-M) (Carnitine palmitoyltransferase 1B)Cpt1bQ924X22
Casein kinase I isoform epsilon (CKI-epsilon) (CKIe) (EC 2.7.11.1)Csnk1eQ9JMK22
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