EVpedia provide top 100+ EV markers, selected according to their identification number.
Based on EV proteomes, we defined the identification number of protein A as the number of datasets which contain protein A.
Therefore, proteins with higher identification numbers were more conserved.

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Protein name Gene symbol UniProt accession Identification number
Extracellular sulfatase Sulf-2 (mSulf-2) (EC 3.1.6.-)Sulf2Q8CFG02
F-box only protein 10Fbxo10 Gm634Q7TQF22
F-box only protein 22Fbxo22 Fbx22Q78JE52
F-box only protein 34Fbxo34Q80XI12
F-box only protein 36Fbxo36Q9CQ242
F-box only protein 4Fbxo4 Fbx4Q8CHQ02
F-box only protein 5 (Early mitotic inhibitor 1)Fbxo5 Emi1Q7TSG32
FANCD2 opposite strand protein (Fanconi anemia group D2 protein opposite strand transcript protein)Fancd2osQ9D4K42
FAS-associated factor 2 (UBX domain-containing protein 8)Faf2 Kiaa0887 Ubxd8Q3TDN22
Fatty acid desaturase 2 (EC 1.14.19.-) (Delta(6) fatty acid desaturase) (D6D) (Delta(6) desaturase) (Delta-6 desaturase)Fads2 Fadsd2Q9Z0R92
Fatty acid desaturase 3 (EC 1.14.19.-)Fads3 MNCb-0629Q9JJE72
Fatty acid synthase (EC 2.3.1.85) [Includes: [Acyl-carrier-protein] S-acetyltransferase (EC 2.3.1.38); [Acyl-carrier-protein] S-malonyltransferase (EC 2.3.1.39); 3-oxoacyl-[acyl-carrier-protein] synthase (EC 2.3.1.41); 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100); 3-hydroxyacyl-[acyl-carrier-protein] dehydratase (EC 4.2.1.59); Enoyl-[acyl-carrier-protein] reductase (EC 1.3.1.39); Oleoyl-[acyl-carrier-protein] hydrolase (EC 3.1.2.14)]FasnP190962
Fatty acyl-CoA reductase 1 (EC 1.2.1.n2) (Male sterility domain-containing protein 2)Far1 Mlstd2Q922J92
FCH domain only protein 2Fcho2Q3UQN22
FERM and PDZ domain-containing protein 1Frmpd1 Kiaa0967A2AKB42
FERM domain-containing protein 8Frmd8Q3UFK82
FERM, RhoGEF and pleckstrin domain-containing protein 1Farp1F8VPU22
Fermitin family homolog 3 (Kindlin-3) (Unc-112-related protein 2)Fermt3 Kind3 Urp2Q8K1B82
FerritinGm5635 EG434729Q3SXD22
FH1/FH2 domain-containing protein 3 (Formin homolog overexpressed in spleen 2) (mFHOS2)Fhod3 Fhos2 Kiaa1695Q76LL62
Fibroblast growth factor 13 (FGF-13) (Fibroblast growth factor homologous factor 2) (FHF-2)Fgf13 Fhf2P703772
Follicle-stimulating hormone receptor (FSH-R) (Follitropin receptor)FshrP353782
Follistatin-related protein 3 (Follistatin-like protein 3) (Follistatin-related gene protein)Fstl3 FlrgQ9EQC72
Forkhead box protein D2 (Mesoderm/mesenchyme forkhead 2) (MF-2)Foxd2 Mf2O353922
Forkhead box protein E1 (Thyroid transcription factor 2) (TTF-2)Foxe1 Titf2Q8R2I02
Forkhead box protein G1 (FoxG1) (Brain factor 1) (BF-1) (BF1) (Forkhead-related protein FKHL1)Foxg1 Fkhl1 Foxg1b Hfhbf1Q609872
Fragile X mental retardation syndrome-related protein 1 (mFxr1p)Fxr1 Fxr1hQ615842
Friend leukemia integration 1 transcription factor (Retroviral integration site protein Fli-1)Fli1 Fli-1P263232
Fructose-bisphosphate aldolase C (EC 4.1.2.13) (Aldolase 3) (Brain-type aldolase) (Scrapie-responsive protein 2) (Zebrin II)Aldoc Aldo3 Scrg2P050632
Fumarate hydratase, mitochondrial (Fumarase) (EC 4.2.1.2) (EF-3)Fh Fh1P978072
FYVE, RhoGEF and PH domain-containing protein 2Fgd2Q8BY352
G patch domain-containing protein 11 (Coiled-coil domain-containing protein 75)Gpatch11 Ccdc75Q3UFS42
G protein-coupled receptor kinase 4 (EC 2.7.11.16) (G protein-coupled receptor kinase GRK4)Grk4 Gprk2lO702912
G protein-coupled receptor kinase 5 (EC 2.7.11.16) (G protein-coupled receptor kinase GRK5)Grk5 Gprk5Q8VEB12
G protein-coupled receptor kinase 6 (EC 2.7.11.16) (G protein-coupled receptor kinase GRK6)Grk6 Gprk6O702932
G-protein-signaling modulator 2 (Pins homolog)Gpsm2 Lgn PinsQ8VDU02
G1/S-specific cyclin-D3Ccnd3 Cyl-3P302822
Galactose-1-phosphate uridylyltransferase (Gal-1-P uridylyltransferase) (EC 2.7.7.12) (UDP-glucose--hexose-1-phosphate uridylyltransferase)GaltQ032492
GalectinLgals3 mCG_6908Q8C2532
Galectin-2 (Gal-2)Lgals2Q9CQW52
Galectin-4 (Gal-4) (Lactose-binding lectin 4)Lgals4Q8K4192
Gamma-glutamyl hydrolase (EC 3.4.19.9) (Conjugase) (FGPH) (Folylpolyglutamate hydrolase) (GH) (Gamma-Glu-x carboxypeptidase)GghQ9Z0L82
Gamma-synuclein (Persyn)Sncg PersynQ9Z0F72
Ganglioside GM2 activator (Cerebroside sulfate activator protein) (GM2-AP) (Sphingolipid activator protein 3) (SAP-3)Gm2aQ606482
Gap junction beta-2 protein (Connexin-26) (Cx26)Gjb2 Cxn-26Q009772
GAS2-like protein 1 (Growth arrest-specific protein 2-like 1)Gas2l1Q8JZP92
Gasdermin-C3Gsdmc3Q8CB122
Gastric intrinsic factor (Intrinsic factor) (IF) (INF)GifP527872
GDNF-inducible zinc finger protein 1 (Zinc finger protein 336)Gzf1 Zfp336Q4VBD92
Gene model 648, (NCBI) (Protein Gm648)Gm648Q3UJ222
Gene model 813, (NCBI) (Protein Gm813)Gm813Q3UWK92
General transcription factor II-I repeat domain-containing protein 2 (GTF2I repeat domain-containing protein 2) (Transcription factor GTF2IRD2)Gtf2ird2Q99NI32
General transcription factor IIF subunit 2 (EC 3.6.4.12) (ATP-dependent helicase GTF2F2) (Transcription initiation factor IIF subunit beta) (TFIIF-beta)Gtf2f2Q8R0A02
General transcription factor IIH subunit 1 (Basic transcription factor 2 62 kDa subunit) (BTF2 p62) (General transcription factor IIH polypeptide 1) (TFIIH basal transcription factor complex p62 subunit)Gtf2h1Q9DBA92
General vesicular transport factor p115 (Protein USO1 homolog) (Transcytosis-associated protein) (TAP) (Vesicle-docking protein)Uso1 VdpQ9Z1Z02
Gephyrin [Includes: Molybdopterin adenylyltransferase (MPT adenylyltransferase) (EC 2.7.7.75) (Domain G); Molybdopterin molybdenumtransferase (MPT Mo-transferase) (EC 2.10.1.1) (Domain E)]GphnQ8BUV32
Glia maturation factor beta (GMF-beta)GmfbQ9CQI32
Glioma pathogenesis-related protein 1 (GliPR 1)Glipr1Q9CWG12
Glucosamine-6-phosphate isomerase 1 (EC 3.5.99.6) (Glucosamine-6-phosphate deaminase 1) (GNPDA 1) (GlcN6P deaminase 1) (Oscillin)Gnpda1 GnpiO889582
Glucose 1,6-bisphosphate synthase (EC 2.7.1.106) (Phosphoglucomutase-2-like 1)Pgm2l1Q8CAA72
Glucose-fructose oxidoreductase domain-containing protein 2 (EC 1.-.-.-)Gfod2Q9CYH52
Glucose-induced degradation protein 4 homolog (Vacuolar import and degradation protein 24 homolog)Gid4Q9CPY62
Glutamate receptor ionotropic, kainate 2 (Grik2 protein)Grik2Q6PAQ02
Glutamate receptor ionotropic, NMDA 2B (GluN2B) (Glutamate [NMDA] receptor subunit epsilon-2) (N-methyl D-aspartate receptor subtype 2B) (NMDAR2B) (NR2B)Grin2bQ010972
Glutamine synthetase (GS) (EC 6.3.1.2) (Glutamate decarboxylase) (EC 4.1.1.15) (Glutamate--ammonia ligase)Glul GlnsP151052
Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 (EC 2.6.1.16) (D-fructose-6-phosphate amidotransferase 1) (Glutamine:fructose-6-phosphate amidotransferase 1) (GFAT 1) (GFAT1) (Hexosephosphate aminotransferase 1)Gfpt1 GfptP478562
Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 2 (EC 2.6.1.16) (D-fructose-6-phosphate amidotransferase 2) (Glutamine:fructose-6-phosphate amidotransferase 2) (GFAT 2) (GFAT2) (Hexosephosphate aminotransferase 2)Gfpt2Q9Z2Z92
Glutamyl-tRNA(Gln) amidotransferase subunit C, mitochondrial (Glu-AdT subunit C) (EC 6.3.5.-)GatcQ8CBY02
Glycerol kinase (GK) (Glycerokinase) (EC 2.7.1.30) (ATP:glycerol 3-phosphotransferase)Gk GykQ645162
Glycerol-3-phosphate acyltransferase 3 (GPAT-3) (EC 2.3.1.15) (1-acyl-sn-glycerol-3-phosphate O-acyltransferase 9) (1-AGP acyltransferase 9) (1-AGPAT 9) (EC 2.3.1.51) (Acyl-CoA:glycerol-3-phosphate acyltransferase 3) (mGPAT3) (Lysophosphatidic acid acyltransferase theta) (LPAAT-theta)Agpat9 Gpat3Q8C0N22
Glycine cleavage system H protein, mitochondrialGcshQ91WK52
Glycine N-acyltransferase-like protein (EC 2.3.1.13) (Acyl-CoA:glycine N-acyltransferase-like) (AAc-like)Gm4952Q5FW572
Glycine N-methyltransferase (EC 2.1.1.20)GnmtQ9QXF82
Glycogen phosphorylase, brain form (EC 2.4.1.1)PygbQ8CI942
Glycoprotein endo-alpha-1,2-mannosidase-like protein (EC 3.2.1.-)Maneal Gm50Q6P1J02
Glycoprotein integral membrane protein 1Ginm1Q91WR62
Glycosyltransferase-like protein LARGE1 (EC 2.4.-.-) (Acetylglucosaminyltransferase-like 1A)Large Kiaa0609 Large1Q9Z1M72
Glypican-4 (K-glypican) [Cleaved into: Secreted glypican-4]Gpc4P516552
GMP synthase [glutamine-hydrolyzing] (EC 6.3.5.2) (GMP synthetase) (Glutamine amidotransferase)GmpsQ3THK72
Golgi pH regulator (Protein GPR89)Gpr89a Gphr Gpr89Q8BS952
Golgi phosphoprotein 3-likeGolph3lQ8R0882
Golgi-specific brefeldin A-resistance factor 1 (Prostaglandin E synthase 2)Gbf1Q6DFZ12
Golgin subfamily A member 1 (Golgin-97)Golga1Q9CW792
Golgin subfamily A member 4 (tGolgin-1)Golga4Q91VW52
Golgin-45 (Basic leucine zipper nuclear factor 1)Blzf1Q8R2X82
GON-4-like proteinGon4lE9Q5072
GPI ethanolamine phosphate transferase 1 (Phosphatidylinositol glycan anchor biosynthesis, class N)Pign mCG_16111G3X9F12
GPI mannosyltransferase 2 (EC 2.4.1.-) (GPI mannosyltransferase II) (GPI-MT-II) (Phosphatidylinositol-glycan biosynthesis class V protein) (PIG-V)PigvQ7TPN32
GRAM domain-containing protein 1AGramd1a D7Bwg0611e Kiaa1533Q8VEF12
GRB2-associated-binding protein 1 (GRB2-associated binder 1) (Growth factor receptor bound protein 2-associated protein 1)Gab1Q9QYY02
GRB2-related adaptor protein 2 (Adapter protein GRID) (GADS protein) (GRB-2-like protein) (GRB2L) (GRB-2-related monocytic adapter protein) (MONA) (Monocytic adapter) (GRBLG) (Growth factor receptor-binding protein) (Hematopoietic cell-associated adaptor protein GrpL)Grap2 Gads Grb2l Grid MonaO891002
Group IIC secretory phospholipase A2 (GIIC sPLA2) (sPLA2-IIC) (EC 3.1.1.4) (14 kDa phospholipase A2) (PLA2-8) (Phosphatidylcholine 2-acylhydrolase 2C)Pla2g2cP480762
Group XIIA secretory phospholipase A2 (GXII sPLA2) (sPLA2-XII) (EC 3.1.1.4) (Phosphatidylcholine 2-acylhydrolase 12A)Pla2g12a Pla2g12Q9EPR22
Growth-regulated alpha protein (C-X-C motif chemokine 1) (Platelet-derived growth factor-inducible protein KC) (Secretory protein N51) [Cleaved into: KC(5-72) (Hematopoietic synergistic factor) (HSF) (KC-T)]Cxcl1 Gro Gro1 Mgsa Scyb1P128502
GTP-binding protein (Interferon gamma inducible protein 47, isoform CRA_a) (Interferon-gamma-inducible GTPase Ifggc1 protein) (Protein Ifi47)Ifi47 Ifggc1 IRG-47 mCG_14415Q616352
GTP-binding protein Rit1 (Ras-like protein expressed in many tissues) (Ras-like without CAAX protein 1)Rit1 RitP704262
GTP-binding protein SAR1bSar1b Sara1b Sara2Q9CQC92
Guanine nucleotide exchange factor DBSMcf2lE9PXE22
Guanine nucleotide exchange factor for Rab-3A (Rab-3A-interacting-like protein 1) (Rab3A-interacting-like protein 1) (Rabin3-like 1)Rab3il1Q8VDV32
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 (G protein subunit beta-2) (Transducin beta chain 2)Gnb2P628802
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