EVpedia provide top 100+ EV markers, selected according to their identification number.
Based on EV proteomes, we defined the identification number of protein A as the number of datasets which contain protein A.
Therefore, proteins with higher identification numbers were more conserved.

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Protein name Gene symbol UniProt accession Identification number
Interleukin-4 receptor subunit alpha (IL-4 receptor subunit alpha) (IL-4R subunit alpha) (IL-4R-alpha) (IL-4RA) (CD antigen CD124) [Cleaved into: Soluble interleukin-4 receptor subunit alpha (Soluble IL-4 receptor subunit alpha) (Soluble IL-4R-alpha) (sIL4Ralpha/prot) (IL-4-binding protein) (IL4-BP)]Il4r Il4raP163822
Interleukin-6 (IL-6) (B-cell hybridoma growth factor) (Interleukin HP-1)Il6 Il-6P085052
Interleukin-7 (IL-7)Il7 Il-7P101682
Interleukin-9 receptor (IL-9 receptor) (IL-9R) (CD antigen CD129)Il9rQ011142
Intermediate conductance calcium-activated potassium channel protein 4 (SK4) (SKCa 4) (SKCa4) (IK1) (KCa3.1) (KCa4)Kcnn4O891092
Intersectin-1 (EH and SH3 domains protein 1)Itsn1 Ese1 ItsnQ9Z0R42
Intraflagellar transport protein 27 homolog (Putative GTP-binding protein RAY-like) (Rab-like protein 4)Ift27 Rabl4 RaylQ9D0P82
IporinRusc2Q3V1Z02
IQ motif and SEC7 domain-containing protein 1Iqsec1 Kiaa0763Q8R0S22
Iroquois-class homeodomain protein IRX-5 (Homeodomain protein IRXB2) (Iroquois homeobox protein 5)Irx5 Irxb2Q9JKQ42
Isoamyl acetate-hydrolyzing esterase 1 homolog (EC 3.1.-.-)Iah1Q9DB292
Isocitrate dehydrogenase 3 (NAD+) beta (Protein Idh3b) (Tumor-related protein)Idh3b mCG_9915Q91VA72
Isovaleryl-CoA dehydrogenase, mitochondrial (IVD) (EC 1.3.8.4)IvdQ9JHI52
Junctional protein associated with coronary artery disease (JCAD)Jcad Gm328 Kiaa1462Q5DTX62
Kallikrein 1-related peptidase b27 (EC 3.4.21.-) (Glandular kallikrein K27) (mGK-27) (Tissue kallikrein 27) (mKlk27)Klk1b27 Klk-27 Klk27Q9JM712
Kallikrein-8 (mK8) (EC 3.4.21.118) (Neuropsin) (NP) (Serine protease 19)Klk8 Nrpn Prss19Q619552
Katanin p60 ATPase-containing subunit A-like 2 (Katanin p60 subunit A-like 2) (EC 3.6.4.3) (p60 katanin-like 2)Katnal2Q9D3R62
Kelch repeat and BTB domain-containing protein 8Kbtbd8 Kiaa1842Q3UQV52
Kelch-like protein 17 (Actinfilin)Klhl17Q6TDP32
Kelch-like protein 24 (Kainate receptor-interacting protein for GluR6) (KRIP6)Klhl24Q8BRG62
Kelch-like protein 8Klhl8P592802
Keratin, type I cytoskeletal 10 (56 kDa cytokeratin) (Cytokeratin-10) (CK-10) (Keratin, type I cytoskeletal 59 kDa) (Keratin-10) (K10)Krt10 Krt1-10P025352
Keratin, type I cytoskeletal 17 (Cytokeratin-17) (CK-17) (Keratin-17) (K17)Krt17 Krt1-17Q9QWL72
Keratin, type I cytoskeletal 27 (Cytokeratin-27) (CK-27) (Keratin complex-1, acidic, gene C29) (Keratin-27) (K27) (Type I inner root sheath-specific keratin-K25irs3)Krt27 c29 Krt1-c29Q9Z3202
Killer cell lectin-like receptor subfamily G member 1 (Mast cell function-associated antigen 2F1)Klrg1 MafaO887132
Kinesin heavy chain isoform 5A (Kinesin heavy chain neuron-specific 1) (Neuronal kinesin heavy chain) (NKHC)Kif5a Kiaa4086 Kif5 Nkhc1P331752
Kinesin light chain 1 (Kinesin light chain-1)Klc1 Kns2Q5UE592
Kinesin light chain 3Klc3Q91W402
Kinesin-like protein KIF16BKif16b Kiaa1590B1AVY72
Kinesin-like protein KIF20A (Kinesin-like protein 174) (Rab6-interacting kinesin-like protein) (Rabkinesin-6)Kif20a Rab6kiflP973292
Kinetochore protein NDC80 homolog (Kinetochore protein Hec1) (Kinetochore-associated protein 2)Ndc80 Hec1 Kntc2Q9D0F12
Kinetochore protein Spc24Spc24 Spbc24Q9D0832
KIR-like receptor 2 KIRL2.1 (Protein Kir3dl2)Kir3dl2 Kir3dl1Q673W22
Kit ligand (Hematopoietic growth factor KL) (Mast cell growth factor) (MGF) (Steel factor) (Stem cell factor) (SCF) (c-Kit ligand) [Cleaved into: Soluble KIT ligand (sKITLG)]Kitlg Kitl Mgf Sl SlfP208262
Klhl15 protein (MCG5462) (Protein Klhl15)Klhl15 mCG_5462A2AAX32
Kremen protein 1 (Dickkopf receptor) (Kringle domain-containing transmembrane protein 1) (Kringle-containing protein marking the eye and the nose)Kremen1 KremenQ99N432
Krueppel-like factor 12 (Transcriptional repressor AP-2rep)Klf12 Ap2repO357382
Krueppel-like factor 13 (Basic transcription element-binding protein 3) (BTE-binding protein 3) (Erythroid transcription factor FKLF-2) (RANTES factor of late activated T-lymphocytes 1) (RFLAT-1) (Transcription factor BTEB3)Klf13 Bteb3 Fklf2Q9JJZ62
Krueppel-like factor 6 (Kruppel-like factor 6, isoform CRA_a)Klf6 mCG_1722Q8BPQ22
Kynurenine--oxoglutarate transaminase 3 (EC 2.6.1.7) (Cysteine-S-conjugate beta-lyase 2) (EC 4.4.1.13) (Kynurenine aminotransferase III) (KATIII) (Kynurenine--glyoxylate transaminase) (EC 2.6.1.63) (Kynurenine--oxoglutarate transaminase III)Ccbl2 Kat3Q71RI92
Kyphoscoliosis peptidaseKyF8VQF82
L antigen family member 3 (ITBA2 protein homolog)Lage3 Itba2Q9CR702
L-2-hydroxyglutarate dehydrogenase, mitochondrial (EC 1.1.99.2) (Duranin)L2hgdhQ91YP02
L-amino-acid oxidase (LAAO) (LAO) (EC 1.4.3.2) (Interleukin-4-induced protein 1) (IL4-induced protein 1) (Protein Fig-1) (mFIG1)Il4i1 Fig1O090462
L-lactate dehydrogenase C chain (LDH-C) (EC 1.1.1.27) (LDH testis subunit) (LDH-X)Ldhc Ldh-3 Ldh3P003422
Lamin-B receptor (Integral nuclear envelope inner membrane protein)LbrQ3U9G92
Laminin subunit beta-2 (Laminin-11 subunit beta) (Laminin-14 subunit beta) (Laminin-15 subunit beta) (Laminin-3 subunit beta) (Laminin-4 subunit beta) (Laminin-7 subunit beta) (Laminin-9 subunit beta) (S-laminin subunit beta) (S-LAM beta)Lamb2 LamsQ612922
Laminin subunit gamma-3 (Laminin-12 subunit gamma) (Laminin-14 subunit gamma) (Laminin-15 subunit gamma)Lamc3Q9R0B62
Large proline-rich protein BAG6 (BAG family molecular chaperone regulator 6) (BCL2-associated athanogene 6) (BAG-6) (BAG6) (HLA-B-associated transcript 3) (Protein Scythe)Bag6 Bat3Q9Z1R22
Late cornified envelope 1F (Protein Lce1f) (RIKEN cDNA 1110055J05, isoform CRA_a)Lce1f 1110055J05Rik mCG_142418B9EJP62
Latent-transforming growth factor beta-binding protein 3 (LTBP-3)Ltbp3Q618102
Latrophilin-1 (Calcium-independent alpha-latrotoxin receptor 1) (CIRL-1) (Lectomedin-2)Lphn1 Kiaa0821 Lec2Q80TR12
LDLR chaperone MESD (Mesoderm development candidate 2) (Mesoderm development protein)Mesdc2 MesdQ9ERE72
Lethal(3)malignant brain tumor-like protein 2 (L(3)mbt-like protein 2)L3mbtl2P591782
Leucine rich repeat containing 57 (Leucine rich repeat containing 57, isoform CRA_a) (Leucine-rich repeat-containing protein 57)Lrrc57 mCG_11983Q8JZX52
Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1 (Leucine-rich repeat neuronal protein 1) (Leucine-rich repeat neuronal protein 6A)Lingo1 Lern1 Lrrn6aQ9D1T02
Leucine-rich repeat and WD repeat-containing protein 1 (ORC-associated protein) (ORCA) (Origin recognition complex-associated protein)LRWD1 OrcaQ8BUI32
Leucine-rich repeat neuronal protein 4 (Neuronal leucine-rich repeat protein 4) (NLRR-4)Lrrn4P593832
Leucine-rich repeat-containing G-protein coupled receptor 4 (G-protein coupled receptor 48)Lgr4 Gpr48A2ARI42
Leucine-rich repeat-containing protein 20Lrrc20Q8CI702
Leucine-rich repeat-containing protein 26 (BK channel auxiliary gamma subunit LRRC26)Lrrc26Q91W202
Leucine-rich repeat-containing protein 28Lrrc28Q3TX512
Leucine-rich repeat-containing protein 41 (Protein Muf1)Lrrc41 Muf1Q8K1C92
Leucine-rich repeat-containing protein 42Lrrc42Q8R2U72
Leucine-rich repeat-containing protein 46Lrrc46Q9DAP02
Leucine-rich repeat-containing protein 59Lrrc59Q922Q82
Leucine-zipper-like transcriptional regulator 1 (LZTR-1)Lztr1 Tcfl2Q9CQ332
Leucyl-cystinyl aminopeptidase (Cystinyl aminopeptidase) (EC 3.4.11.3) (Oxytocinase) (OTase)LnpepQ8C1292
Leukocyte receptor cluster member 1 homologLeng1Q9DB982
Leukotriene-B(4) omega-hydroxylase 2 (EC 1.14.13.30) (CYPIVF3) (Cytochrome P450 4F3) (Cytochrome P450-LTB-omega) (Leukotriene-B(4) 20-monooxygenase 2)Cyp4f3 Cyp4f18Q99N162
Ligand-dependent nuclear receptor-interacting factor 1Lrif1Q8CDD92
LIM and senescent cell antigen-like-containing domain protein 1 (Particularly interesting new Cys-His protein 1) (PINCH-1)Lims1 Pinch1Q99JW42
LIM domain-binding protein 1 (LDB-1) (Carboxyl-terminal LIM domain-binding protein 2) (CLIM-2) (LIM domain-binding factor CLIM2) (mLdb1) (Nuclear LIM interactor)Ldb1 NliP706622
LIM homeobox transcription factor 1-alpha (LIM/homeobox protein 1.1) (LMX-1.1) (LIM/homeobox protein LMX1A)Lmx1aQ9JKU82
LIM/homeobox protein Lhx9 (LIM homeobox protein 9)Lhx9Q9WUH22
Lipase maturation factor 2 (Transmembrane protein 112B) (Transmembrane protein 153)Lmf2 Tmem112b Tmem153Q8C3X82
Lipid phosphate phosphatase-related protein type 4 (EC 3.1.3.4) (Brain-specific phosphatidic acid phosphatase-like protein 1) (Plasticity-related gene 1 protein) (PRG-1)Lppr4 D3Bwg0562e Kiaa0455 Prg1Q7TME02
Lipid phosphate phosphohydrolase 2 (EC 3.1.3.4) (PAP2-gamma) (PAP2-G) (Phosphatidate phosphohydrolase type 2c) (Phosphatidic acid phosphatase 2c) (PAP-2c) (PAP2c)Ppap2c Lpp2Q9DAX22
Lipopolysaccharide-induced tumor necrosis factor-alpha factor homolog (LPS-induced TNF-alpha factor homolog) (Estrogen-enhanced transcript protein) (mEET) (LITAF-like protein) (NEDD4 WW domain-binding protein 3)Litaf N4wbp3 Tbx1Q9JLJ02
Lipopolysaccharide-responsive and beige-like anchor protein (Beige-like protein)Lrba Bgl LbaQ9ESE12
Lipoprotein lipase (LPL) (EC 3.1.1.34)LplP111522
Liprin-alpha 4 (Protein Ppfia4)Ppfia4 ppfia4B8QI362
Long-chain fatty acid transport protein 1 (FATP-1) (Fatty acid transport protein 1) (EC 6.2.1.-) (Solute carrier family 27 member 1)Slc27a1 Fatp Fatp1Q607142
Long-chain fatty acid transport protein 4 (FATP-4) (Fatty acid transport protein 4) (EC 6.2.1.-) (Solute carrier family 27 member 4)Slc27a4 Acsvl4 Fatp4Q91VE02
Long-chain specific acyl-CoA dehydrogenase, mitochondrial (LCAD) (EC 1.3.8.8)AcadlP511742
Long-chain-fatty-acid--CoA ligase 3 (EC 6.2.1.3) (Long-chain acyl-CoA synthetase 3) (LACS 3)Acsl3 Acs3 Facl3Q9CZW42
Long-chain-fatty-acid--CoA ligase 4 (EC 6.2.1.3) (Long-chain acyl-CoA synthetase 4) (LACS 4) (mACS4)Acsl4 Acs4 Facl4Q9QUJ72
Low-density lipoprotein receptor-related protein 10 (LRP-10)Lrp10 Lrp9Q7TQH72
Lymphocyte-specific protein 1 (52 kDa phosphoprotein) (pp52) (Lymphocyte-specific antigen WP34) (S37 protein)Lsp1 Pp52 S37 Wp34P199732
LYR motif-containing protein 2Lyrm2Q8R0332
LYR motif-containing protein 5 (Growth hormone-inducible soluble protein)Lyrm5Q91V162
Lysine--tRNA ligase (EC 6.1.1.6) (Lysyl-tRNA synthetase) (LysRS)KarsQ99MN12
Lysine-rich coiled-coil protein 1Krcc1Q99JT52
Lysine-specific demethylase 5A (EC 1.14.11.-) (Histone demethylase JARID1A) (Jumonji/ARID domain-containing protein 1A) (Retinoblastoma-binding protein 2) (RBBP-2)Kdm5a Jarid1a Rbp2Q3UXZ92
Lysophosphatidic acid receptor 1 (LPA receptor 1) (LPA-1) (Lysophosphatidic acid receptor Edg-2) (Rec1.3) (VZG-1)Lpar1 Edg2 Gpcr26 Lpa1 Vzg1P617932
Lysophosphatidic acid receptor 4 (LPA receptor 4) (LPA-4) (G-protein coupled receptor 23) (P2Y purinoceptor 9) (P2Y9) (Purinergic receptor 9)Lpar4 Gpr23 Lpa4 P2y9Q8BLG22
Lysophosphatidylcholine acyltransferase 1 (LPC acyltransferase 1) (LPCAT-1) (LysoPC acyltransferase 1) (mLPCAT1) (EC 2.3.1.23) (1-acylglycerophosphocholine O-acyltransferase) (1-alkylglycerophosphocholine O-acetyltransferase) (EC 2.3.1.67) (Acetyl-CoA:lyso-platelet-activating factor acetyltransferase) (Acetyl-CoA:lyso-PAF acetyltransferase) (Lyso-PAF acetyltransferase) (LysoPAFAT) (Acyltransferase-like 2)Lpcat1 Aytl2Q3TFD22
Lysophospholipid acyltransferase 5 (LPLAT 5) (EC 2.3.1.-) (1-acylglycerophosphocholine O-acyltransferase) (EC 2.3.1.23) (1-acylglycerophosphoethanolamine O-acyltransferase) (EC 2.3.1.n7) (1-acylglycerophosphoserine O-acyltransferase) (EC 2.3.1.n6) (Lysophosphatidylcholine acyltransferase) (LPCAT) (Lyso-PC acyltransferase) (Lysophosphatidylcholine acyltransferase 3) (Lyso-PC acyltransferase 3) (mLPCAT3) (Lysophosphatidylethanolamine acyltransferase) (LPEAT) (Lyso-PE acyltransferase) (Lysophosphatidylserine acyltransferase) (LPSAT) (Lyso-PS acyltransferase) (Membrane-bound O-acyltransferase domain-containing protein 5) (O-acyltransferase domain-containing protein 5)Lpcat3 Grcc3f Mboat5 Oact5Q91V012
Lysosomal acid phosphatase (LAP) (EC 3.1.3.2)Acp2P246382
Lysosomal Pro-X carboxypeptidase (EC 3.4.16.2) (Proline carboxypeptidase) (Prolylcarboxypeptidase) (PRCP)PrcpQ7TMR02
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