EVpedia provide top 100+ EV markers, selected according to their identification number.
Based on EV proteomes, we defined the identification number of protein A as the number of datasets which contain protein A.
Therefore, proteins with higher identification numbers were more conserved.

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Protein name Gene symbol UniProt accession Identification number
Proton-coupled amino acid transporter 3 (Proton/amino acid transporter 3) (Solute carrier family 36 member 3) (Tramdorin-2)Slc36a3 Pat3 Tramd2Q811P02
Protoporphyrinogen oxidase (PPO) (EC 1.3.3.4)PpoxP511752
Pumilio homolog 2Pum2 Kiaa0235Q80U582
Puromycin-sensitive aminopeptidase (PSA) (EC 3.4.11.14) (Cytosol alanyl aminopeptidase) (AAP-S)Npepps PsaQ110112
Putative RNA-binding protein Luc7-like 1Luc7lQ9CYI42
Putative sodium-coupled neutral amino acid transporter 9 (Solute carrier family 38 member 9)Slc38a9Q8BGD62
Putative uncharacterized proteinItga6Q8CC062
Putative uncharacterized proteinKcnab3Q8C4392
Putative uncharacterized proteinGm5114 EG330513Q8CDW02
Putative uncharacterized proteinGm1322Q3TYN92
Putative uncharacterized protein (Fragment)SynpoQ3TY322
Pyrroline-5-carboxylate reductase 3 (P5C reductase 3) (P5CR 3) (EC 1.5.1.2) (Pyrroline-5-carboxylate reductase-like protein)PycrlQ9DCC42
Pyruvate kinase PKM (EC 2.7.1.40) (Pyruvate kinase muscle isozyme)Pkm Pk3 Pkm2 PykmP524802
Queuine tRNA-ribosyltransferase subunit QTRTD1 (EC 2.4.2.29) (Queuine tRNA-ribosyltransferase domain-containing protein 1)Qtrtd1B8ZXI12
Quinone oxidoreductase (EC 1.6.5.5) (NADPH:quinone reductase) (Zeta-crystallin)CryzP471992
Rab GTPase-activating protein 1-likeRabgap1l Hhl Kiaa0471A6H6A92
Rab11 family-interacting protein 5 (Rab11-FIP5) (Rab11-interacting protein Rip11)Rab11fip5 D6Ertd32e Rip11Q8R3612
RAD50-interacting protein 1 (RAD50 interactor 1) (RINT-1)Rint1Q8BZ362
Radial spoke head protein 6 homolog A (Radial spoke head-like protein 1)Rsph6a Rshl1Q8CDR22
Radical S-adenosyl methionine domain-containing protein 2 (Viperin) (Virus inhibitory protein, endoplasmic reticulum-associated, interferon-inducible)Rsad2 Vig1Q8CBB92
RAF proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (Proto-oncogene c-RAF) (cRaf) (Raf-1)Raf1 CrafQ99N572
Raftlin-2 (Raft-linking protein 2)Rftn2Q8CHX72
Ral guanine nucleotide dissociation stimulator-like 1 (RalGDS-like 1)Rgl1 RglQ606952
Ras association domain-containing protein 3Rassf3Q99P512
Ras GTPase-activating protein 3 (GAP1(IP4BP)) (GapIII) (Ins P4-binding protein)Rasa3Q607902
Ras-associating and dilute domain-containing proteinRadil Kiaa1849Q69Z892
Ras-related GTP-binding protein C (Rag C) (RagC) (GTPase-interacting protein 2) (TIB929)RragcQ99K702
Ras-related protein R-Ras2Rras2P620712
Ras-related protein Rab-10Rab10P610272
Ras-related protein Rab-11A (Rab-11)Rab11a Rab11P624922
Ras-related protein Rab-18Rab18P352932
Ras-related protein Rab-1BRab1bQ9D1G12
Ras-related protein Rab-33BRab33bO359632
Ras-related protein Ral-BRalbQ9JIW92
RCC1 and BTB domain-containing protein 1 (Regulator of chromosome condensation and BTB domain-containing protein 1)Rcbtb1Q6NXM22
Receptor expression-enhancing protein 2Reep2Q8VCD62
Receptor-binding cancer antigen expressed on SiSo cells (Cancer-associated surface antigen RCAS1) (Estrogen receptor-binding fragment-associated gene 9 protein)Ebag9 Rcas1Q9D0V72
Receptor-transporting protein 2Rtp2 Gm605Q80ZI22
Receptor-type tyrosine-protein phosphatase alpha (Protein-tyrosine phosphatase alpha) (R-PTP-alpha) (EC 3.1.3.48) (LCA-related phosphatase) (PTPTY-28)Ptpra Lrp PtpaP180522
Receptor-type tyrosine-protein phosphatase eta (Protein-tyrosine phosphatase eta) (R-PTP-eta) (EC 3.1.3.48) (HPTP beta-like tyrosine phosphatase) (Protein-tyrosine phosphatase receptor type J) (R-PTP-J) (Susceptibility to colon cancer 1) (CD antigen CD148)Ptprj Byp Scc1Q644552
Regenerating islet-derived protein 4 (REG-4)Reg4Q9D8G52
Regulator of G-protein signaling 12 (RGS12)Rgs12Q8CGE92
Regulator of G-protein signaling 13 (RGS13)Rgs13Q8K4432
Regulator of G-protein signaling 14 (RGS14) (RAP1/RAP2-interacting protein) (RPIP1)Rgs14P974922
Regulator of G-protein signaling 20 (RGS20) (Regulator of G-protein signaling Z1)Rgs20 Rgsz1Q9QZB12
Regulator of G-protein signaling 3 (RGS3) (C2PA)Rgs3Q9DC042
Regulator of G-protein signaling 6 (RGS6)Rgs6Q9Z2H22
Regulator of microtubule dynamics protein 1 (RMD-1) (mRMD-1) (Microtubule-associated protein) (Protein FAM82B)Rmdn1 Fam82bQ9DCV42
Regulator of microtubule dynamics protein 2 (RMD-2) (mRMD-2) (Protein FAM82A1)Rmdn2 Fam82a Fam82a1Q8BSE02
Replication initiator 1 (Zinc finger protein 464) (Zfp-464)Repin1 Zfp464Q5U4E22
Required for meiotic nuclear division protein 1 homologRmnd1Q8CI782
Resistin (Adipose tissue-specific secretory factor) (ADSF) (Adipose-specific cysteine-rich secreted protein A12-alpha) (Cysteine-rich secreted protein FIZZ3)Retn Fizz3Q99P872
Retinaldehyde-binding protein 1 (Cellular retinaldehyde-binding protein)Rlbp1 CralbpQ9Z2752
Retinoblastoma-binding protein 5 (RBBP-5)Rbbp5Q8BX092
Retinoic acid early-inducible protein 1-beta (RAE-1-beta)Raet1bO086032
Retinol dehydrogenase 12 (EC 1.1.1.-)Rdh12Q8BYK42
Retinol dehydrogenase 7 (EC 1.1.1.105) (Cis-retinol/3alpha-hydroxysterol short-chain dehydrogenase isozyme 2) (Cis-retinol/androgen dehydrogenase type 2) (CRAD-2)Rdh7 Crad2O884512
RGM domain family member B (DRG11-responsive axonal guidance and outgrowth of neurite) (DRAGON)RgmbQ7TQ332
Rho GTPase-activating protein 17 (Neuron-associated developmentally-regulated protein) (Nadrin) (Rho-type GTPase-activating protein 17)Arhgap17Q3UIA22
Rho GTPase-activating protein 19 (Rho-type GTPase-activating protein 19)Arhgap19Q8BRH32
Rho GTPase-activating protein 33 (Rho-type GTPase-activating protein 33) (Sorting nexin-26) (Tc10/CDC42 GTPase-activating protein)Arhgap33 Snx26 TcgapQ80YF92
Rho GTPase-activating protein 5Arhgap5E9PYT02
Rho guanine nucleotide exchange factor 12Arhgef12F8VQN62
Rho guanine nucleotide exchange factor 19 (Ephexin-2) (Weakly similar to Rho GEF 5)Arhgef19 WgefQ8BWA82
Rho guanine nucleotide exchange factor 40 (Protein SOLO)Arhgef40 SoloQ3UPH72
Rho guanine nucleotide exchange factor 7 (Beta-Pix) (PAK-interacting exchange factor beta) (p85SPR)Arhgef7 Kiaa0142 Pak3bpQ9ES282
Rho-related BTB domain-containing protein 1Rhobtb1Q9DAK32
Rho-related GTP-binding protein RhoQ (Ras-like protein TC10)Rhoq Arhq Tc10Q8R5272
Rhomboid-related protein 4 (RRP4) (EC 3.4.21.105) (Rhomboid domain-containing protein 1) (mRHBDD1) (Rhomboid-like protein 4)Rhbdd1 Rhbdl4 MSD-50 MSD50Q8BHC72
Rhombotin-1 (Cysteine-rich protein TTG-1) (LIM domain only protein 1) (LMO-1) (T-cell translocation protein 1)Lmo1 Rbtn1 Rhom1 Ttg1Q924W92
Rhombotin-2 (Cysteine-rich protein TTG-2) (LIM domain only protein 2) (LMO-2) (T-cell translocation protein 2)Lmo2 Rbtn-2 Rbtn2 Rhom-2P258012
Ribonuclease 4 (Ribonuclease, RNase A family 4)Rnase4Q8C7E42
Ribonuclease H2 subunit A (RNase H2 subunit A) (EC 3.1.26.4) (Ribonuclease HI large subunit) (RNase HI large subunit) (Ribonuclease HI subunit A)Rnaseh2a RnasehiQ9CWY82
Ribonuclease H2 subunit C (RNase H2 subunit C) (Ribonuclease HI subunit C)Rnaseh2c Ayp1Q9CQ182
Ribonuclease kappa (RNase K) (RNase kappa) (EC 3.1.-.-)Rnasek D11Bwg0434eQ8K3C02
Ribonuclease P protein subunit p29 (EC 3.1.26.5)Pop4 Rpp29Q9CR082
Ribonucleoside-diphosphate reductase large subunit (EC 1.17.4.1) (Ribonucleoside-diphosphate reductase subunit M1) (Ribonucleotide reductase large subunit)Rrm1P077422
Ribonucleoside-diphosphate reductase subunit M2 B (EC 1.17.4.1) (TP53-inducible ribonucleotide reductase M2 B) (p53-inducible ribonucleotide reductase small subunit 2-like protein) (p53R2)Rrm2b P53r2Q6PEE32
Ribose-phosphate pyrophosphokinase 1 (EC 2.7.6.1) (Phosphoribosyl pyrophosphate synthase I) (PRS-I)Prps1Q9D7G02
Ribosomal biogenesis protein LAS1L (Protein LAS1 homolog)Las1lA2BE282
Ribosomal proteinRpl10a mCG_123122 mCG_18533Q5XJF62
Ribosomal RNA processing protein 36 homologRrp36Q3UFY02
Ribosome biogenesis protein BRX1 homolog (Brix domain-containing protein 2)Brix1 Brix Bxdc2Q9DCA52
Rieske domain-containing proteinRfesdQ8K2P62
RING finger and SPRY domain-containing protein 1Rspry1 Kiaa1972Q8BVR62
RING finger protein 214Rnf214Q8BFU32
RING finger protein 32 (Limb region protein 2)Rnf32 Lmbr2Q9JIT12
RING finger protein 44Rnf44 Kiaa1100Q3UHJ82
RNA binding protein fox-1 homolog 3 (Fox-1 homolog C) (Hexaribonucleotide-binding protein 3) (Fox-3) (Neuronal nuclei) (NeuN)Rbfox3 D11Bwg0517e Hrnbp3Q8BIF22
RNA polymerase II elongation factor ELL (Eleven-nineteen lysine-rich leukemia protein)EllO088562
RNA polymerase II subunit A C-terminal domain phosphatase SSU72 (CTD phosphatase SSU72) (EC 3.1.3.16)Ssu72Q9CY972
RNA-binding motif, single-stranded-interacting protein 1 (Single-stranded DNA-binding protein MSSP-1)Rbms1 Mssp Mssp1Q91W592
RNA-binding motif, single-stranded-interacting protein 3Rbms3Q8BWL52
RNA-binding protein 42 (RNA-binding motif protein 42)Rbm42Q91V812
RNA-binding protein 44 (RNA-binding motif protein 44)Rbm44 Gm817Q3V0892
RNA-binding protein 7 (RNA-binding motif protein 7)Rbm7Q9CQT22
RNA-binding protein 8A (RNA-binding motif protein 8A) (Ribonucleoprotein RBM8A)Rbm8a Rbm8Q9CWZ32
RNA-binding protein Musashi homolog 1 (Musashi-1)Msi1 Msi1hQ614742
RNA-binding Raly-like proteinRalylQ8BTF82
Roundabout homolog 4Robo4Q8C3102
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