EVpedia provide top 100+ EV markers, selected according to their identification number.
Based on EV proteomes, we defined the identification number of protein A as the number of datasets which contain protein A.
Therefore, proteins with higher identification numbers were more conserved.

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Protein name Gene symbol UniProt accession Identification number
Transaldolase (EC 2.2.1.2)Taldo1 Tal TaldoQ930922
Transcription activator BRG1 (EC 3.6.4.-) (ATP-dependent helicase SMARCA4) (BRG1-associated factor 190A) (BAF190A) (Protein brahma homolog 1) (SNF2-beta) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4)Smarca4 Baf190a Brg1 Snf2b Snf2l4Q3TKT42
Transcription cofactor HES-6 (Hairy and enhancer of split 6)Hes6Q9JHE62
Transcription elongation factor 1 homologElof1P600032
Transcription elongation factor A protein 1 (Transcription elongation factor S-II protein 1) (Transcription elongation factor TFIIS.o)Tcea1 TceatP107112
Transcription factor 7-like 1 (HMG box transcription factor 3) (TCF-3) (mTCF-3)Tcf7l1 Tcf3Q9Z1J12
Transcription factor COE1 (O/E-1) (OE-1) (Early B-cell factor)Ebf1 Coe1 EbfQ078022
Transcription factor ETV6 (ETS translocation variant 6) (ETS-related protein Tel1) (Tel)Etv6 Tel Tel1P973602
Transcription factor jun-DJund Jun-d Jund1P150662
Transcription factor SOX-6 (SOX-LZ)Sox6 Sox-6P406452
Transcription factor Sp1Sp1O890902
Transcription factor SPT20 homolog (p38-interacting protein) (p38IP)Supt20h D3Ertd300e Fam48a Supt20Q7TT002
Transcription initiation factor TFIID subunit 1Taf1D3YZK42
Transcription initiation factor TFIID subunit 11 (TFIID subunit p30-beta) (Transcription initiation factor TFIID 28 kDa subunit) (TAF(II)28) (TAFII-28) (TAFII28)Taf11Q99JX12
Transcription termination factor, mitochondrial (Mitochondrial transcription termination factor 1) (mTERF)MterfQ8CHZ92
Transcriptional protein SWT1Swt1Q9DBQ92
Transcriptional repressor NF-X1 (m-Nfx.1) (EC 6.3.2.-) (Nuclear transcription factor, X box-binding protein 1)Nfx1B1AY102
Transcriptional repressor p66 alpha (GATA zinc finger domain-containing protein 2A)Gatad2aQ8CHY62
Transducin-like enhancer protein 3 (ESG) (Grg-3)Tle3 EsgQ081222
Translation factor Guf1, mitochondrial (EC 3.6.5.-) (Elongation factor 4 homolog) (EF-4) (GTPase Guf1) (Ribosomal back-translocase)Guf1Q8C3X42
Translation initiation factor eIF-2B subunit delta (eIF-2B GDP-GTP exchange factor subunit delta)Eif2b4 Eif2b Eif2bd Jgr1aQ617492
Translation initiation factor IF-2, mitochondrial (IF-2(Mt)) (IF-2Mt) (IF2(mt))Mtif2Q91YJ52
Translational activator of cytochrome c oxidase 1 (Coiled-coil domain-containing protein 44) (Translational activator of mitochondrially-encoded cytochrome c oxidase 1)Taco1 Ccdc44Q8K0Z72
Translocator protein (Mitochondrial benzodiazepine receptor) (PKBS) (Peripheral-type benzodiazepine receptor) (PBR)Tspo Bzrp MbrP506372
Translocator protein 2 (Peripheral-type benzodiazepine receptor-like protein 1)Tspo2 Bzrpl1Q9CRZ82
Translocon-associated protein subunit delta (TRAP-delta) (Signal sequence receptor subunit delta) (SSR-delta)Ssr4Q621862
Transmembrane 9 superfamily member 3Tm9sf3 SmbpQ9ET302
Transmembrane and TPR repeat-containing protein 4Tmtc4Q8BG192
Transmembrane emp24 domain-containing protein 3 (p24 family protein gamma-4) (p24gamma4)Tmed3Q78IS12
Transmembrane emp24 domain-containing protein 9 (Glycoprotein 25L2) (p24 family protein alpha-2) (p24alpha2)Tmed9 Gp25l2Q99KF12
Transmembrane gamma-carboxyglutamic acid protein 2 (NEDD4 WW domain-binding protein 1) (Proline-rich gamma-carboxyglutamic acid protein 2) (Proline-rich Gla protein 2)Prrg2 N4wbp1Q8R1822
Transmembrane protease serine 12 (EC 3.4.21.-)Tmprss12Q3V0Q72
Transmembrane protease serine 2 (EC 3.4.21.-) (Epitheliasin) (Plasmic transmembrane protein X) [Cleaved into: Transmembrane protease serine 2 non-catalytic chain; Transmembrane protease serine 2 catalytic chain]Tmprss2Q9JIQ82
Transmembrane protein 107Tmem107Q9CPV02
Transmembrane protein 11, mitochondrial (Protein PM1)Tmem11Q8BK082
Transmembrane protein 128Tmem128Q9CZB92
Transmembrane protein 150B (Transmembrane protein 224)Tmem150b Tmem224Q8R2182
Transmembrane protein 150CTmem150cQ8C8S32
Transmembrane protein 164Tmem164Q6PHN72
Transmembrane protein 165 (TPA-regulated locus protein) (Transmembrane protein PFT27) (Transmembrane protein TPARL)Tmem165 TparlP528752
Transmembrane protein 176A (Gene signature 188) (Kidney-expressed gene 2 protein)Tmem176a Gs188 Keg2Q9DCS12
Transmembrane protein 177Tmem177Q8BPE42
Transmembrane protein 18Tmem18Q3TUD92
Transmembrane protein 180Tmem180Q6PDE82
Transmembrane protein 186Tmem186Q9CR762
Transmembrane protein 192Tmem192Q9CXT72
Transmembrane protein 234Tmem234Q8R1E72
Transmembrane protein 237 (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 4 protein homolog)Tmem237 Als2cr4Q3V0J12
Transmembrane protein 260Tmem260Q8BMD62
Transmembrane protein 261Tmem261Q9CQ002
Transmembrane protein 59 (Thymic dendritic cell-derived factor 1)Tmem59 ORF18 Tdcf1Q9QY732
Transmembrane protein 69Tmem69Q3KQJ02
Transmembrane protein 9Tmem9Q9CR232
Transmembrane protein C9orf91 homolog0Q8R2392
Tribbles homolog 3 (TRB-3) (Neuronal cell death-inducible putative kinase)Trib3 Nipk Trb3Q8K4K22
Trichorhinophalangeal syndrome I (Human), isoform CRA_b (Zinc finger transcription factor Trps1)Trps1 mCG_20645G3UW902
Trimethyllysine dioxygenase, mitochondrial (EC 1.14.11.8) (Epsilon-trimethyllysine 2-oxoglutarate dioxygenase) (TML hydroxylase) (TML-alpha-ketoglutarate dioxygenase) (TML dioxygenase) (TMLD)Tmlhe TmlhQ91ZE02
Tripartite motif-containing protein 26 (Zinc finger protein 173)Trim26 Znf173Q99PN32
Tripartite motif-containing protein 44 (Protein DIPB) (Protein Mc7)Trim44 DipbQ9QXA72
Tripeptidyl-peptidase 1 (TPP-1) (EC 3.4.14.9) (Lysosomal pepstatin-insensitive protease) (LPIC) (Tripeptidyl aminopeptidase) (Tripeptidyl-peptidase I) (TPP-I)Tpp1 Cln2O890232
tRNA (adenine(58)-N(1))-methyltransferase catalytic subunit TRMT61A (EC 2.1.1.220) (tRNA(m1A58)-methyltransferase subunit TRMT61A) (tRNA(m1A58)MTase subunit TRMT61A)Trmt61a Trm61Q80XC22
tRNA (cytosine(34)-C(5))-methyltransferase (EC 2.1.1.203) (Myc-induced SUN domain-containing protein) (Misu) (NOL1/NOP2/Sun domain family member 2)Nsun2 D13Wsu123e MisuQ1HFZ02
tRNA (guanine-N(7)-)-methyltransferase (EC 2.1.1.33) (Methyltransferase-like protein 1) (tRNA (guanine(46)-N(7))-methyltransferase) (tRNA(m7G46)-methyltransferase)Mettl1Q9Z1202
tRNA modification GTPase GTPBP3, mitochondrial (GTP-binding protein 3)Gtpbp3Q923K42
tRNA pseudouridine synthase-like 1 (EC 5.4.99.-) (tRNA pseudouridylate synthase-like 1) (tRNA-uridine isomerase-like 1)Pusl1A2ADA52
tRNA-dihydrouridine(47) synthase [NAD(P)(+)]-like (EC 1.3.1.-) (tRNA-dihydrouridine synthase 3-like)Dus3lQ91XI12
tRNA-splicing endonuclease subunit Sen2 (EC 3.1.27.9) (tRNA-intron endonuclease Sen2)Tsen2 Sen2Q6P7W52
Tropomodulin-1 (Erythrocyte tropomodulin) (E-Tmod)Tmod1 TmodP498132
Tryptophan 2,3-dioxygenase (TDO) (EC 1.13.11.11) (Tryptamin 2,3-dioxygenase) (Tryptophan oxygenase) (TO) (TRPO) (Tryptophan pyrrolase) (Tryptophanase)Tdo2 TdoP487762
Tumor necrosis factor receptor superfamily member 5 (B-cell surface antigen CD40) (Bp50) (CD40L receptor) (CD antigen CD40)Cd40 Tnfrsf5P275122
Tumor suppressor candidate 2 (Fusion 1 protein) (Fus-1 protein) (PDGFA-associated protein 2)Tusc2 Fus1 Lgcc Pdap2Q9WVF82
Tumor suppressor candidate 3 (Magnesium uptake/transporter TUSC3) (Protein N33)Tusc3 N33Q8BTV12
Tumor susceptibility gene 101 protein (ESCRT-I complex subunit TSG101)Tsg101Q611872
Type 2 phosphatidylinositol 4,5-bisphosphate 4-phosphatase (Type 2 PtdIns-4,5-P2 4-Ptase) (EC 3.1.3.78) (PtdIns-4,5-P2 4-Ptase II) (Transmembrane protein 55A)Tmem55aQ9CZX72
Type II inositol 3,4-bisphosphate 4-phosphatase (EC 3.1.3.66) (Inositol polyphosphate 4-phosphatase type II)Inpp4bQ6P1Y82
Tyrosine-protein kinase Blk (EC 2.7.10.2) (B lymphocyte kinase) (p55-Blk)BlkP162772
Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-Src kinase) (Protein-tyrosine kinase MPK-2) (p50CSK)CskP412412
Tyrosine-protein kinase Fer (EC 2.7.10.2) (Proto-oncogene c-Fer) (p94-Fer)Fer Fert2P704512
Tyrosine-protein kinase Fes/Fps (EC 2.7.10.2) (Proto-oncogene c-Fes)Fes FpsP168792
Tyrosine-protein kinase ITK/TSK (EC 2.7.10.2) (IL-2-inducible T-cell kinase) (Kinase EMT) (Kinase TLK) (T-cell-specific kinase)Itk Emt Tlk TskQ035262
Tyrosine-protein kinase Yes (EC 2.7.10.2) (Proto-oncogene c-Yes) (p61-Yes)Yes1 YesQ047362
Tyrosine-protein phosphatase non-receptor type 1 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1B) (PTP-1B) (Protein-tyrosine phosphatase HA2) (PTP-HA2)Ptpn1P358212
Tyrosine-protein phosphatase non-receptor type 14 (EC 3.1.3.48) (Protein-tyrosine phosphatase PTP36)Ptpn14Q621302
U11/U12 small nuclear ribonucleoprotein 35 kDa protein (U11/U12 snRNP 35 kDa protein) (U1 snRNP-binding protein homolog)Snrnp35 U1snrnpbpQ9D3842
U2 snRNP-associated SURP motif-containing protein (140 kDa Ser/Arg-rich domain protein) (U2-associated protein SR140)U2surp Sr140Q6NV832
U4/U6 small nuclear ribonucleoprotein Prp3 (Pre-mRNA-splicing factor 3)Prpf3Q922U12
U4/U6.U5 tri-snRNP-associated protein 1 (Hypoxia-associated factor) (Squamous cell carcinoma antigen recognized by T-cells 1) (SART-1) (mSART-1)Sart1 HafQ9Z3152
U5 small nuclear ribonucleoprotein 200 kDa helicase (EC 3.6.4.13) (BRR2 homolog) (U5 snRNP-specific 200 kDa protein) (U5-200KD)Snrnp200 Kiaa0788Q6P4T22
U6 snRNA phosphodiesterase (EC 3.1.4.-)Usb1Q91W782
UBA-like domain-containing protein 2Ubald2 Fam100bQ8BQH42
Ubiquinone biosynthesis protein COQ4 homolog, mitochondrial (Coenzyme Q biosynthesis protein 4 homolog)Coq4Q8BGB82
Ubiquitin carboxyl-terminal hydrolase 1 (EC 3.4.19.12) (Deubiquitinating enzyme 1) (Ubiquitin thioesterase 1) (Ubiquitin-specific-processing protease 1)Usp1Q8BJQ22
Ubiquitin carboxyl-terminal hydrolase 15 (EC 3.4.19.12) (Deubiquitinating enzyme 15) (Ubiquitin thioesterase 15) (Ubiquitin-specific-processing protease 15)Usp15 Kiaa0529Q8R5H12
Ubiquitin carboxyl-terminal hydrolase 20 (EC 3.4.19.12) (Deubiquitinating enzyme 20) (Ubiquitin thioesterase 20) (Ubiquitin-specific-processing protease 20) (VHL-interacting deubiquitinating enzyme 2)Usp20 Kiaa1003 Vdu2Q8C6M12
Ubiquitin carboxyl-terminal hydrolase 25 (EC 3.4.19.12) (Deubiquitinating enzyme 25) (Ubiquitin thioesterase 25) (Ubiquitin-specific-processing protease 25) (mUSP25)Usp25P570802
Ubiquitin carboxyl-terminal hydrolase 3 (EC 3.4.19.12) (Deubiquitinating enzyme 3) (Ubiquitin thioesterase 3) (Ubiquitin-specific-processing protease 3)Usp3Q91W362
Ubiquitin carboxyl-terminal hydrolase 33 (EC 3.4.19.12) (Deubiquitinating enzyme 33) (Ubiquitin thioesterase 33) (Ubiquitin-specific-processing protease 33) (VHL-interacting deubiquitinating enzyme 1)Usp33 Vdu1Q8R5K22
Ubiquitin carboxyl-terminal hydrolase 34 (EC 3.4.19.12) (Deubiquitinating enzyme 34) (Ubiquitin thioesterase 34) (Ubiquitin-specific-processing protease 34)Usp34 Kiaa0570 Murr2Q6ZQ932
Ubiquitin carboxyl-terminal hydrolase 4 (EC 3.4.19.12) (Deubiquitinating enzyme 4) (Ubiquitin thioesterase 4) (Ubiquitin-specific-processing protease 4) (Ubiquitous nuclear protein)Usp4 UnpP351232
Ubiquitin carboxyl-terminal hydrolase 46 (EC 3.4.19.12) (Deubiquitinating enzyme 46) (Ubiquitin thioesterase 46) (Ubiquitin-specific-processing protease 46)Usp46P620692
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