EVpedia provide top 100+ EV markers, selected according to their identification number.
Based on EV proteomes, we defined the identification number of protein A as the number of datasets which contain protein A.
Therefore, proteins with higher identification numbers were more conserved.

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Protein name Gene symbol UniProt accession Identification number
Zinc finger protein 330 (Nucleolar autoantigen 36) (Nucleolar cysteine-rich protein)Znf330 Noa36 Zfp330Q922H92
Zinc finger protein 414Znf414 Zfp414Q9DCK42
Zinc finger protein 423 (Early B-cell factor-associated zinc finger protein) (Olf1/EBF-associated zinc finger protein) (Smad- and Olf-interacting zinc finger protein)Znf423 Ebfaz Kiaa0760 Nur12 Oaz Zfp423Q80TS52
Zinc finger protein 48 (Zinc finger protein 553)Znf48 Zfp48 Zfp553 Znf553Q3US172
Zinc finger protein 511Znf511 Zfp511Q6P0X22
Zinc finger protein 622Znf622 D15Ertd806e Zfp622Q91VY92
Zinc finger protein 628 (Zinc finger protein expressed in embryonal cells and certain adult organs)Znf628 Zec Zfp628Q8CJ782
Zinc finger protein 638 (Nuclear protein 220) (Zinc finger matrin-like protein)Znf638 Np220 ZfmlQ614642
Zinc finger protein 64 (Zinc finger protein 64, isoform CRA_b)Zfp64 mCG_20647A2AQR42
Zinc finger protein 668Znf668 Zfp668Q8K2R52
Zinc finger protein 672Znf672 Zfp672Q99LH42
Zinc finger protein AEBP2 (Adipocyte enhancer-binding protein 2) (AE-binding protein 2)Aebp2Q9Z2482
Zinc finger protein with KRAB and SCAN domains 5 (Zinc finger protein 95) (Zfp-95)Zkscan5 Zfp95Q9Z1D82
Zinc finger SWIM domain-containing protein 8Zswim8 Kiaa0913Q3UHH12
Zinc fingers and homeoboxes protein 3 (Triple homeobox protein 1) (Zinc finger and homeodomain protein 3)Zhx3 Kiaa0395 Tix1Q8C0Q22
Zinc phosphodiesterase ELAC protein 2 (EC 3.1.26.11) (ElaC homolog protein 2) (Ribonuclease Z 2) (RNase Z 2) (tRNA 3 endonuclease 2) (tRNase Z 2)Elac2Q80Y812
Zinc transporter 1 (ZnT-1) (Solute carrier family 30 member 1)Slc30a1 Znt1Q607382
Zinc transporter 5 (ZnT-5) (Solute carrier family 30 member 5)Slc30a5 Znt5Q8R4H92
Zinc transporter SLC39A7 (Histidine-rich membrane protein Ke4) (Solute carrier family 39 member 7) (Zrt-, Irt-like protein 7) (ZIP7)Slc39a7 H2-Ke4 Hke4Q311252
Zinc transporter ZIP13 (Solute carrier family 39 member 13) (Zrt- and Irt-like protein 13) (ZIP-13)Slc39a13 Zip13Q8BZH02
Zinc transporter ZIP5 (Solute carrier family 39 member 5) (Zrt- and Irt-like protein 5) (ZIP-5)Slc39a5 Zip5Q9D8562
Zinc-alpha-2-glycoprotein (Zn-alpha-2-GP) (Zn-alpha-2-glycoprotein)Azgp1Q647262
[Protein ADP-ribosylarginine] hydrolase (ADP-ribosylarginine hydrolase) (EC 3.2.2.19) (ADP-ribose-L-arginine cleaving enzyme)Adprh Arh1P549232
1,4-alpha-glucan-branching enzyme (EC 2.4.1.18) (Brancher enzyme) (Glycogen-branching enzyme)Gbe1Q9D6Y91
1-acyl-sn-glycerol-3-phosphate acyltransferase alpha (EC 2.3.1.51) (1-acylglycerol-3-phosphate O-acyltransferase 1) (1-AGP acyltransferase 1) (1-AGPAT 1) (Lysophosphatidic acid acyltransferase alpha) (LPAAT-alpha)Agpat1O350831
1-acyl-sn-glycerol-3-phosphate acyltransferase epsilon (EC 2.3.1.51) (1-acylglycerol-3-phosphate O-acyltransferase 5) (1-AGP acyltransferase 5) (1-AGPAT 5) (Lysophosphatidic acid acyltransferase epsilon) (LPAAT-epsilon)Agpat5 D8Ertd319eQ9D1E81
1-phosphatidylinositol 3-phosphate 5-kinase (Phosphatidylinositol 3-phosphate 5-kinase) (EC 2.7.1.150) (FYVE finger-containing phosphoinositide kinase) (PIKfyve) (Phosphatidylinositol 3-phosphate 5-kinase type III) (PIPkin-III) (Type III PIP kinase) (p235)Pikfyve Kiaa0981 Pip5k3Q9Z1T61
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 (EC 3.1.4.11) (Phosphoinositide phospholipase C-gamma-1) (Phospholipase C-gamma-1) (PLC-gamma-1)Plcg1 Plcg-1Q620771
11-cis retinol dehydrogenase (11-cis RDH) (11-cis RoDH) (EC 1.1.1.315) (9-cis retinol dehydrogenase) (Cis-retinol dehydrogenase) (Retinol dehydrogenase 5)Rdh5 cRDH rdh RDH4O552401
14 kDa phosphohistidine phosphatase (EC 3.1.3.-) (Phosphohistidine phosphatase 1)Phpt1 Php14Q9DAK91
14-3-3 protein sigma (Stratifin)Sfn Mkrn3O704561
15 kDa selenoprotein41532Q9ERR71
16.5 kDa submandibular gland glycoproteinSpt1Q9DA651
17beta-hydroxysteroid dehydrogenase type 10/short chain L-3-hydroxyacyl-CoA dehydrogenase (3-hydroxyacyl-CoA dehydrogenase type-2) (Hydroxysteroid (17-beta) dehydrogenase 10)Hsd17b10 Hadh2 Hsd17b10/SchadQ99N151
2'-5'olygoadenylate synthetase 1G (MCG141816) (Protein Oas1g)Oas1g mCG_141816Q8K4691
2,4-dienoyl-CoA reductase, mitochondrial (EC 1.3.1.34) (2,4-dienoyl-CoA reductase [NADPH]) (4-enoyl-CoA reductase [NADPH])Decr1Q9CQ621
2010315B03Rik protein (Fragment)2010315B03RikQ05C341
2310005G13Rik protein (Protein 2310005G13Rik) (RIKEN cDNA 2310005G13)2310005G13Rik mCG_129495B7ZWJ51
25-hydroxycholesterol 7-alpha-hydroxylase (EC 1.14.13.100) (Cytochrome P450 7B1) (Hippocampal transcript 1 protein) (HCT-1) (Oxysterol 7-alpha-hydroxylase)Cyp7b1Q609911
26S protease regulatory subunit 4 (P26s4) (26S proteasome AAA-ATPase subunit RPT2) (Proteasome 26S subunit ATPase 1)Psmc1P621921
26S protease regulatory subunit 6A (26S proteasome AAA-ATPase subunit RPT5) (Proteasome 26S subunit ATPase 3) (Tat-binding protein 1) (TBP-1)Psmc3 Tbp1O886851
26S proteasome non-ATPase regulatory subunit 1 (26S proteasome regulatory subunit RPN2) (26S proteasome regulatory subunit S1)Psmd1Q3TXS71
26S proteasome non-ATPase regulatory subunit 10 (26S proteasome regulatory subunit p28) (Gankyrin)Psmd10Q9Z2X21
26S proteasome non-ATPase regulatory subunit 3 (26S proteasome regulatory subunit RPN3) (26S proteasome regulatory subunit S3) (Proteasome subunit p58) (Transplantation antigen P91A) (Tum-P91A antigen)Psmd3 P91a Tstap91aP146851
28 kDa heat- and acid-stable phosphoprotein (PDGF-associated protein) (PAP) (PDGFA-associated protein 1) (PAP1)Pdap1Q3UHX21
28S ribosomal protein S10, mitochondrialMrps10E9QJS01
28S ribosomal protein S11, mitochondrial (Mitochondrial ribosomal protein S11, isoform CRA_b)Mrps11 mCG_6300Q3U8Y11
28S ribosomal protein S15, mitochondrial (MRP-S15) (S15mt)Mrps15 Rpms15Q9DC711
28S ribosomal protein S16, mitochondrial (MRP-S16) (S16mt)Mrps16 Rpms16Q9CPX71
28S ribosomal protein S17, mitochondrial (MRP-S17) (S17mt)Mrps17 Rpms17Q9CQE31
28S ribosomal protein S18b, mitochondrial (MRP-S18-b) (Mrps18-b) (S18mt-b) (28S ribosomal protein S18-2, mitochondrial) (MRP-S18-2)Mrps18bQ99N841
28S ribosomal protein S22, mitochondrial (MRP-S22) (S22mt)Mrps22 Rpms22Q9CXW21
28S ribosomal protein S24, mitochondrial (MRP-S24) (S24mt)Mrps24Q9CQV51
28S ribosomal protein S25, mitochondrial (MRP-S25) (S25mt)Mrps25 Rpms25Q9D1251
28S ribosomal protein S27, mitochondrial (MRP-S27) (S27mt)Mrps27Q8BK721
28S ribosomal protein S30, mitochondrial (MRP-S30) (S30mt)Mrps30Q9D0G01
3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 3 (3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type III) (3-beta-HSD III) [Includes: 3-beta-hydroxy-Delta(5)-steroid dehydrogenase (EC 1.1.1.145) (3-beta-hydroxy-5-ene steroid dehydrogenase) (Progesterone reductase); Steroid Delta-isomerase (EC 5.3.3.1) (Delta-5-3-ketosteroid isomerase)]Hsd3b3P261501
3'(2'),5'-bisphosphate nucleotidase 1 (EC 3.1.3.7) (Bisphosphate 3'-nucleotidase 1) (PAP-inositol 1,4-phosphatase) (PIP)Bpnt1Q9Z0S11
3'-5' exoribonuclease 1 (EC 3.1.-.-) (3'-5' exonuclease ERI1) (Eri-1 homolog) (Histone mRNA 3'-exonuclease 1)Eri1 3'exo Thex1Q7TMF21
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase (EC 5.3.3.5) (Cholestenol Delta-isomerase) (Delta(8)-Delta(7) sterol isomerase) (D8-D7 sterol isomerase) (Emopamil-binding protein)Ebp MsiP702451
3-hydroxyisobutyrate dehydrogenase, mitochondrial (HIBADH) (EC 1.1.1.31)HibadhQ99L131
3-oxo-5-alpha-steroid 4-dehydrogenase 1 (EC 1.3.1.22) (SR type 1) (Steroid 5-alpha-reductase 1) (S5AR 1)Srd5a1Q68FF91
39S ribosomal protein L11, mitochondrial (L11mt) (MRP-L11)Mrpl11Q9CQF01
39S ribosomal protein L16, mitochondrial (L16mt) (MRP-L16)Mrpl16Q99N931
39S ribosomal protein L21, mitochondrial (L21mt) (MRP-L21)Mrpl21 D9Wsu149Q9D1N91
39S ribosomal protein L24, mitochondrial (L24mt) (MRP-L24)Mrpl24Q9CQ061
39S ribosomal protein L27, mitochondrial (L27mt) (MRP-L27)Mrpl27Q99N921
39S ribosomal protein L41, mitochondrial (L41mt) (MRP-L41)Mrpl41Q9CQN71
39S ribosomal protein L46, mitochondrial (L46mt) (MRP-L46)Mrpl46Q9EQI81
4-aminobutyrate aminotransferase, mitochondrial (EC 2.6.1.19) ((S)-3-amino-2-methylpropionate transaminase) (EC 2.6.1.22) (GABA aminotransferase) (GABA-AT) (Gamma-amino-N-butyrate transaminase) (GABA transaminase) (GABA-T) (L-AIBAT)Abat GabatP619221
4-hydroxy-2-oxoglutarate aldolase, mitochondrial (EC 4.1.3.16) (Dihydrodipicolinate synthase-like) (DHDPS-like protein) (Probable 2-keto-4-hydroxyglutarate aldolase) (Probable KHG-aldolase)Hoga1 DhdpslQ9DCU91
4-hydroxyphenylpyruvate dioxygenase-like protein (EC 1.13.-.-) (Glyoxalase domain-containing protein 1)Hpdl Gloxd1Q8K2481
4732496O08Rik protein (Protein Pramef8) (RIKEN cDNA 4732496O08, isoform CRA_a)Pramef8 4732496O08Rik mCG_18887Q8CE241
4933411G11Rik protein (MCG23562, isoform CRA_b) (Protein 4933411G11Rik) (Uncharacterized protein)4933411G11Rik Spdyb Spdye4 mCG_23562Q8CDE81
5' exonuclease Apollo (EC 3.1.-.-) (DNA cross-link repair 1B protein) (SNM1 homolog B)Dclre1b Snm1bQ8C7W71
5'-AMP-activated protein kinase subunit beta-1 (AMPK subunit beta-1) (AMPKb)Prkab1Q9R0781
5'-nucleotidase domain containing 2 (Protein Nt5dc2)Nt5dc2Q91X761
5'-nucleotidase domain-containing protein 1 (EC 3.1.3.-) (Cytosolic 5'-nucleotidase II-like protein 1)Nt5dc1 Nt5c2l1Q8C5P51
5-formyltetrahydrofolate cyclo-ligase (EC 6.3.3.2) (5,10-methenyl-tetrahydrofolate synthetase) (MTHFS) (Methenyl-THF synthetase)MthfsQ9D1101
5-hydroxyisourate hydrolase (HIU hydrolase) (HIUHase) (EC 3.5.2.17) (Transthyretin-related protein)UrahQ9CRB31
5-hydroxytryptamine (Serotonin) receptor 5B (5-hydroxytryptamine receptor 5B)Htr5b mCG_142485G3X9C61
5-hydroxytryptamine receptor 1B (5-HT-1B) (5-HT1B) (Serotonin receptor 1B)Htr1b 5ht1bP283341
5-oxoprolinase (EC 3.5.2.9) (5-oxo-L-prolinase) (5-OPase) (Pyroglutamase)OplahQ8K0101
55 kDa erythrocyte membrane protein (p55) (Membrane protein, palmitoylated 1)Mpp1P702901
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1 (6PF-2-K/Fru-2,6-P2ase 1) (PFK/FBPase 1) (6PF-2-K/Fru-2,6-P2ase liver isozyme) [Includes: 6-phosphofructo-2-kinase (EC 2.7.1.105); Fructose-2,6-bisphosphatase (EC 3.1.3.46)]Pfkfb1P702661
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 (6PF-2-K/Fru-2,6-P2ase 4) (PFK/FBPase 4) (6PF-2-K/Fru-2,6-P2ase testis-type isozyme) [Includes: 6-phosphofructo-2-kinase (EC 2.7.1.105); Fructose-2,6-bisphosphatase (EC 3.1.3.46)]Pfkfb4Q6DTY71
6-phosphofructokinase, liver type (EC 2.7.1.11) (Phosphofructo-1-kinase isozyme B) (PFK-B) (Phosphofructokinase 1) (Phosphohexokinase)Pfkl Pfk-l PfkbP123821
6-phosphofructokinase, muscle type (EC 2.7.1.11) (Phosphofructo-1-kinase isozyme A) (PFK-A) (Phosphofructokinase-M) (Phosphofructokinase 1) (Phosphohexokinase)Pfkm Pfk-m PfkaP478571
6-phosphogluconolactonase (6PGL) (EC 3.1.1.31)PglsQ9CQ601
60S ribosomal export protein NMD3Nmd3Q99L481
60S ribosomal protein L15Rpl15Q9CZM21
60S ribosomal protein L32Rpl32P629111
60S ribosomal protein L34Rpl34Q9D1R91
7-dehydrocholesterol reductase (7-DHC reductase) (EC 1.3.1.21) (Sterol Delta(7)-reductase)Dhcr7O884551
72 kDa inositol polyphosphate 5-phosphatase (EC 3.1.3.36) (Phosphatidylinositol 4,5-bisphosphate 5-phosphatase) (Phosphatidylinositol polyphosphate 5-phosphatase type IV)Inpp5eQ9JII11
A disintegrin and metallopeptidase domain 34 (A disintegrin and metallopeptidase domain 34, isoform CRA_a) (Adam34 protein) (Protein Adam34)Adam34 mCG_141116A2RSG81
A disintegrin and metalloproteinase with thrombospondin motifs 10 (ADAM-TS 10) (ADAM-TS10) (ADAMTS-10) (EC 3.4.24.-)Adamts10P584591
A disintegrin and metalloproteinase with thrombospondin motifs 12 (ADAM-TS 12) (ADAM-TS12) (ADAMTS-12) (EC 3.4.24.-)Adamts12Q811B31
A disintegrin and metalloproteinase with thrombospondin motifs 15 (ADAM-TS 15) (ADAM-TS15) (ADAMTS-15) (EC 3.4.24.-)Adamts15P593841
A kinase (PRKA) anchor protein 8-like (A kinase (PRKA) anchor protein 8-like, isoform CRA_a) (A-kinase anchor protein 8-like)Akap8l mCG_14258Q5RL571
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