EVpedia provide top 100+ EV markers, selected according to their identification number.
Based on EV proteomes, we defined the identification number of protein A as the number of datasets which contain protein A.
Therefore, proteins with higher identification numbers were more conserved.

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Protein name Gene symbol UniProt accession Identification number
A-kinase anchor protein 2 (AKAP-2) (AKAP expressed in kidney and lung) (AKAP-KL) (Protein kinase A-anchoring protein 2) (PRKA2)Akap2O549311
A-kinase anchor protein 7 isoform gamma (AKAP-7 isoform gamma) (A-kinase anchor protein 18) (AKAP-18) (Protein kinase A-anchoring protein 7 isoform gamma) (PRKA7 isoform gamma)Akap7 Akap18Q7TN791
A11 integrinItga11Q7TQC31
A3 subunit of vacuolar-adenosine triphosphatase (Osteoclast-specific 116-kDa V-ATPase subunit) (Protein Tcirg1) (T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 protein A3, isoform CRA_b)Tcirg1 Oc116 mCG_3894Q9JHF51
Abelson tyrosine-protein kinase 2 (Abl2 protein)Abl2B2RQ571
Abhydrolase domain-containing protein 4 (EC 3.1.1.-) (Alpha/beta-hydrolase 4) (Lyso-N-acylphosphatidylethanolamine lipase)Abhd4Q8VD661
Acetyl-CoA acetyltransferase, cytosolic (EC 2.3.1.9) (Cytosolic acetoacetyl-CoA thiolase)Acat2Q8CAY61
Acetyl-CoA carboxylase 1 (ACC1) (EC 6.4.1.2) (ACC-alpha) (Acetyl-CoA carboxylase 265) [Includes: Biotin carboxylase (EC 6.3.4.14)]Acaca Acac Gm738Q5SWU91
Acetyl-coenzyme A synthetase 2-like, mitochondrial (EC 6.2.1.1) (Acetate--CoA ligase 2) (Acetyl-CoA synthetase 2) (AceCS2) (Acyl-CoA synthetase short-chain family member 1)Acss1 Acas2 Acas2lQ99NB11
Acetylcholine receptor subunit alphaChrna1 AcraP047561
Achaete-scute homolog 3 (ASH-3) (mASH-3) (mASH3) (bHLH transcriptional regulator Sgn-1)Ascl3 Mash3 Sgn1Q9JJR71
Acid ceramidase (AC) (ACDase) (Acid CDase) (EC 3.5.1.23) (Acylsphingosine deacylase) (N-acylsphingosine amidohydrolase) [Cleaved into: Acid ceramidase subunit alpha; Acid ceramidase subunit beta]Asah1 AsahQ9WV541
Acid phosphatase-like protein 2 (EC 3.1.3.2)Acpl2Q8BHA91
Acid trehalase-like protein 1 (EC 3.2.1.-)Athl1Q8BP561
Acid-sensing ion channel 1 (ASIC1) (Acid-sensing ion channel) (Amiloride-sensitive cation channel 2, neuronal) (Brain sodium channel 2) (BNaC2)Asic1 Accn2 Asic Bnac2Q6NXK81
Aconitate hydratase, mitochondrial (Aconitase) (EC 4.2.1.3) (Citrate hydro-lyase)Aco2Q99KI01
Acrosin-binding protein (Proacrosin-binding protein sp32)AcrbpQ3V1401
Actin filament-associated protein 1 (110 kDa actin filament-associated protein) (AFAP-110)Afap1 Kiaa3018Q80YS61
Actin, alpha cardiac muscle 1 (Alpha-cardiac actin)Actc1 ActcP680331
Actin-binding protein IPP (Intracisternal A particle-promoted polypeptide) (IPP) (Murine IAP-promoted placenta-expressed protein) (Protein MIPP)Ipp MippP285751
Actin-like protein 7B (Actin-like-7-beta) (Testis-specific actin-1) (T-actin-1)Actl7b Tact1Q9QY831
Actin-like protein 9Actl9 Actl7cQ8CG271
Actin-related protein 10 (Actin-related protein 11)Actr10 Act11 Actr11 Arp11Q9QZB71
Actin-related protein 2 (Actin-like protein 2)Actr2 Arp2P611611
Actin-related protein 2/3 complex subunit 2 (Arp2/3 complex 34 kDa subunit) (p34-ARC)Arpc2Q9CVB61
Actin-related protein 2/3 complex subunit 5-like protein (Arp2/3 complex 16 kDa subunit 2) (ARC16-2)Arpc5lQ9D8981
Actin-related protein 3B (ARP3-beta) (Actin-like protein 3B)Actr3bQ641P01
Actin-related protein 6 (mArp6)Actr6Q9D8641
Actin-related protein 8Actr8 Arp8Q8R2S91
Activating molecule in BECN1-regulated autophagy protein 1Ambra1 Kiaa1736A2AH221
Activating signal cointegrator 1 complex subunit 3 (EC 3.6.4.12)Ascc3E9PZJ81
Activator of basal transcription 1Abt1Q9QYL71
Activin receptor type-1B (EC 2.7.11.30) (Activin receptor type IB) (ACTR-IB) (Activin receptor-like kinase 4) (ALK-4) (Serine/threonine-protein kinase receptor R2) (SKR2)Acvr1b Alk4Q612711
Activin receptor type-1C (EC 2.7.11.30) (Activin receptor type IC) (ACTR-IC) (Activin receptor-like kinase 7) (ALK-7)Acvr1c Alk7Q8K3481
Acyl-CoA dehydrogenase family member 10 (ACAD-10) (EC 1.3.99.-)Acad10Q8K3701
Acyl-CoA dehydrogenase family member 11 (ACAD-11) (EC 1.3.99.-)Acad11Q80XL61
Acyl-CoA desaturase 1 (EC 1.14.19.1) (Delta(9)-desaturase 1) (Delta-9 desaturase 1) (Fatty acid desaturase 1) (Stearoyl-CoA desaturase 1)Scd1P135161
Acyl-CoA synthetase family member 3, mitochondrial (EC 6.2.1.-)Acsf3Q3URE11
Acyl-CoA synthetase family member 4 (EC 6.2.1.-) (2-aminoadipic 6-semialdehyde dehydrogenase) (Protein LYS2 homolog) (Putative aminoadipate-semialdehyde dehydrogenase) (EC 1.2.1.31)Aasdh Acsf4 U26Q80WC91
Acyl-CoA-binding domain-containing protein 6Acbd6Q9D0611
Acyl-coenzyme A amino acid N-acyltransferase 2 (EC 2.3.1.-)Acnat2Q8BGG91
Acyl-coenzyme A synthetase ACSM4, mitochondrial (EC 6.2.1.2) (Olfactory specific medium-chain acyl CoA synthetase) (O-MACS)Acsm4 OmacsQ80W401
Acyl-coenzyme A thioesterase 10, mitochondrial (Acyl-CoA thioesterase 10) (EC 3.1.2.-) (Mitochondrial 48 kDa acyl-CoA thioester hydrolase 2) (Mt-ACT48.2)Acot10Q32MW31
Acyl-coenzyme A thioesterase 11 (Acyl-CoA thioesterase 11) (EC 3.1.2.-) (Acyl-CoA thioester hydrolase 11) (Adipose-associated thioesterase) (Brown fat-inducible thioesterase) (BFIT)Acot11 Bfit TheaQ8VHQ91
Acyl-coenzyme A thioesterase 8 (Acyl-CoA thioesterase 8) (EC 3.1.2.27) (Choloyl-coenzyme A thioesterase) (Peroxisomal acyl-CoA thioesterase 2) (PTE-2) (Peroxisomal acyl-coenzyme A thioester hydrolase 1) (PTE-1) (Peroxisomal long-chain acyl-CoA thioesterase 1)Acot8 Pte1 Pte2P581371
Acylphosphatase-1 (EC 3.6.1.7) (Acylphosphatase, organ-common type isozyme) (Acylphosphate phosphohydrolase 1)Acyp1 AcypeP563761
Acylphosphatase-2 (EC 3.6.1.7) (Acylphosphatase, muscle type isozyme) (Acylphosphate phosphohydrolase 2)Acyp2 AcypP563751
ADAM6b (Protein Adam6b)Adam6bQ6IMH71
ADAMTS-like 5, isoform CRA_c (Protein Adamtsl5)Adamtsl5 mCG_13390D3Z6891
Adenosine deaminase domain-containing protein 1 (Testis nuclear RNA-binding protein)Adad1 TenrQ5SUE71
Adenosine deaminase-like protein (EC 3.5.4.-)AdalQ80SY61
Adenosine receptor A3 (RIKEN cDNA 1700001D09)Adora3 1700001D09Rik mCG_10757G3X8R91
Adenylate cyclase type 6 (EC 4.6.1.1) (ATP pyrophosphate-lyase 6) (Adenylate cyclase type VI) (Adenylyl cyclase 6) (Ca(2+)-inhibitable adenylyl cyclase)Adcy6Q013411
Adenylate cyclase type 7 (EC 4.6.1.1) (ATP pyrophosphate-lyase 7) (Adenylate cyclase type VII) (Adenylyl cyclase 7)Adcy7P518291
Adenylate cyclase type 9 (EC 4.6.1.1) (ATP pyrophosphate-lyase 9) (Adenylate cyclase type IX) (Adenylyl cyclase 9) (Adenylyl cyclase type 10) (ACTP10)Adcy9P518301
Adenylate kinase isoenzyme 6 (AK6) (EC 2.7.4.3) (Coilin-interacting nuclear ATPase protein) (Dual activity adenylate kinase/ATPase) (AK/ATPase)Taf9 Ak6 CinapQ8VCP81
Adipocyte enhancer-binding protein 1 (AE-binding protein 1) (Aortic carboxypeptidase-like protein)Aebp1 AclpQ640N11
Adiponectin (30 kDa adipocyte complement-related protein) (Adipocyte complement-related 30 kDa protein) (ACRP30) (Adipocyte, C1q and collagen domain-containing protein) (Adipocyte-specific protein AdipoQ)Adipoq Acdc Acrp30 Apm1Q609941
ADP-ribose pyrophosphatase, mitochondrial (EC 3.6.1.13) (ADP-ribose diphosphatase) (ADP-ribose phosphohydrolase) (Adenosine diphosphoribose pyrophosphatase) (ADPR-PPase) (Nucleoside diphosphate-linked moiety X motif 9) (Nudix motif 9)Nudt9Q8BVU51
ADP-ribosyl cyclase 2 (EC 3.2.2.5) (Antigen BP3) (BP-3 alloantigen) (Bone marrow stromal antigen 1) (BST-1) (Cyclic ADP-ribose hydrolase 2) (cADPr hydrolase 2) (Leukocyte antigen 65) (Ly-65) (CD antigen CD157)Bst1 Bp-3 Bp3 Ly65Q642771
ADP-ribosylation factor 4Arf4P617501
ADP-ribosylation factor 5Arf5P840841
ADP-ribosylation factor-binding protein GGA3 (Golgi-localized, gamma ear-containing, ARF-binding protein 3)Gga3 Kiaa0154Q8BMI31
ADP-ribosylation factor-like protein 1Arl1P612111
ADP-ribosylation factor-like protein 10 (ADP-ribosylation factor-like membrane-associated protein)Arl10 Arl10a Arm1Q9QXJ41
ADP-ribosylation factor-like protein 4C (ADP-ribosylation factor-like 7)Arl4c Arl7P612081
ADP-sugar pyrophosphatase (EC 3.6.1.13) (8-oxo-dGDP phosphatase) (EC 3.6.1.58) (Nucleoside diphosphate-linked moiety X motif 5) (Nudix motif 5)Nudt5Q9JKX61
ADP/ATP translocase 4 (ADP,ATP carrier protein 4) (Adenine nucleotide translocator 4) (ANT 4) (Solute carrier family 25 member 31) (Sperm flagellar energy carrier protein)Slc25a31 Aac4 Ant4 SfecQ3V1321
Adrenocorticotropic hormone receptor (ACTH receptor) (ACTH-R) (Adrenocorticotropin receptor) (Melanocortin receptor 2) (MC2-R)Mc2r ActhrQ643261
Adrenodoxin-like protein, mitochondrial (Ferredoxin-1-like protein)Fdx1lQ9CPW21
Adseverin (Gelsolin-like protein) (Scinderin)ScinQ606041
AF4/FMR2 family member 2 (FMR2P) (Fragile X mental retardation protein 2 homolog) (Protein FMR-2) (Protein Ox19)Aff2 Fmr2 Ox19O551121
AF4/FMR2 family member 3Aff3F8WJA71
Afadin- and alpha-actinin-binding protein (ADIP) (Afadin DIL domain-interacting protein)Ssx2ipQ8VC661
AFG3-like protein 2 (EC 3.4.24.-)Afg3l2Q8JZQ21
AftiphilinAftph AfthQ80WT51
AgrinAgrnM0QWP11
AH receptor-interacting protein (AIP) (Aryl-hydrocarbon receptor-interacting protein)AipO089151
Aladin (Adracalin)AaasP587421
Alanine aminotransferase 1 (ALT1) (EC 2.6.1.2) (Glutamate pyruvate transaminase 1) (GPT 1) (Glutamic--alanine transaminase 1) (Glutamic--pyruvic transaminase 1)Gpt Gpt1Q8QZR51
Alanine aminotransferase 2 (ALT2) (EC 2.6.1.2) (Glutamate pyruvate transaminase 2) (GPT 2) (Glutamic--alanine transaminase 2) (Glutamic--pyruvic transaminase 2)Gpt2 Aat2Q8BGT51
Alanine--tRNA ligase, mitochondrial (EC 6.1.1.7) (Alanyl-tRNA synthetase) (AlaRS)Aars2 Aarsl Gm89 Kiaa1270Q14CH71
Aldehyde dehydrogenase X, mitochondrial (EC 1.2.1.3) (Aldehyde dehydrogenase family 1 member B1)Aldh1b1 AldhxQ9CZS11
Aldehyde dehydrogenase, cytosolic 1 (EC 1.2.1.3) (ALDH class 1) (ALDH-E1) (ALHDII) (Aldehyde dehydrogenase family 1 member A7) (Aldehyde dehydrogenase phenobarbital-inducible)Aldh1a7 Aldh-pbO359451
Aldo-keto reductase family 1 member C13 (EC 1.1.1.-)Akr1c13Q8VC281
Aldose reductase-related protein 2 (AR) (EC 1.1.1.21) (Aldehyde reductase) (Fibroblast growth factor-regulated protein) (Protein FR-1)Akr1b8 FgfrpP453771
Alkaline ceramidase 1 (AlkCDase 1) (Alkaline CDase 1) (maCER1) (EC 3.5.1.23) (Acylsphingosine deacylase 3) (N-acylsphingosine amidohydrolase 3)Acer1 Asah3Q8R4X11
All-trans-retinol 13,14-reductase (EC 1.3.99.23) (All-trans-13,14-dihydroretinol saturase) (RetSat) (PPAR-alpha-regulated and starvation-induced gene protein)Retsat PpsigQ64FW21
Alpha-(1,3)-fucosyltransferase 9 (EC 2.4.1.-) (Fucosyltransferase 9) (Fucosyltransferase IX) (Fuc-TIX) (FucT-IX) (Galactoside 3-L-fucosyltransferase)Fut9O888191
Alpha-(1,6)-fucosyltransferase (Alpha1-6FucT) (EC 2.4.1.68) (Fucosyltransferase 8) (GDP-L-Fuc:N-acetyl-beta-D-glucosaminide alpha1,6-fucosyltransferase) (GDP-fucose--glycoprotein fucosyltransferase) (Glycoprotein 6-alpha-L-fucosyltransferase)Fut8Q9WTS21
Alpha-1,3-galactosyltransferase 2 (A3galt2) (EC 2.4.1.87) (Isoglobotriaosylceramide synthase) (iGb3 synthase) (iGb3S)A3galt2 Igb3sQ3V1N91
Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase (EC 2.4.1.101) (N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase I) (GNT-I) (GlcNAc-T I)Mgat1 Gnt1P278081
Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A (EC 2.4.1.155) (Alpha-mannoside beta-1,6-N-acetylglucosaminyltransferase) (GlcNAc-T V) (GNT-V) (Mannoside acetylglucosaminyltransferase 5) (N-acetylglucosaminyl-transferase V)Mgat5Q8R4G61
Alpha-1-acid glycoprotein 2 (AGP 2) (Orosomucoid-2) (OMD 2)Orm2 Agp-2 Orm-2P073611
Alpha-1-syntrophinSnta1A2AKD71
Alpha-2,8-sialyltransferase 8F (EC 2.4.99.-) (Sialyltransferase 8F) (SIAT8-F) (Sialyltransferase St8Sia VI) (ST8SiaVI)St8sia6 Siat8fQ8K4T11
Alpha-actinin-2 (Alpha-actinin skeletal muscle isoform 2) (F-actin cross-linking protein)Actn2Q9JI911
Alpha-adducin (Erythrocyte adducin subunit alpha)Add1Q9QYC01
Alpha-aminoadipic semialdehyde dehydrogenase (Alpha-AASA dehydrogenase) (EC 1.2.1.31) (Aldehyde dehydrogenase family 7 member A1) (EC 1.2.1.3) (Antiquitin-1) (Betaine aldehyde dehydrogenase) (EC 1.2.1.8) (Delta1-piperideine-6-carboxylate dehydrogenase) (P6c dehydrogenase)Aldh7a1 Ald7a1Q9DBF11
Alpha-catulin (Alpha-catenin-related protein) (ACRP) (Catenin alpha-like protein 1)Ctnnal1 Catnal1O883271
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