EVpedia provide top 100+ EV markers, selected according to their identification number.
Based on EV proteomes, we defined the identification number of protein A as the number of datasets which contain protein A.
Therefore, proteins with higher identification numbers were more conserved.

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Protein name Gene symbol UniProt accession Identification number
Cyclin-G2Ccng2O089181
Cyclin-L1 (Cyclin-L) (Cyclin Ania-6a)Ccnl1 Ania6a Ccn1Q52KE71
Cyclin-related protein FAM58B (Cyclin-related protein FAM58A)Fam58b Fam58aQ8QZR81
Cystatin-8 (Cystatin-related epididymal spermatogenic protein) (Cystatin-related epididymal-specific protein)Cst8 CresP327661
Cysteine and glycine-rich protein 3 (Cysteine-rich protein 3) (CRP3) (LIM domain protein, cardiac) (Muscle LIM protein)Csrp3 Clp MlpP504621
Cysteine protease ATG4C (EC 3.4.22.-) (AUT-like 3 cysteine endopeptidase) (Autophagin-3) (Autophagy-related cysteine endopeptidase 3) (Autophagy-related protein 4 homolog C)Atg4c Apg4c Autl3Q811C21
Cysteine protease ATG4D (EC 3.4.22.-) (AUT-like 4 cysteine endopeptidase) (Autophagin-4) (Autophagy-related cysteine endopeptidase 4) (Autophagy-related protein 4 homolog D) [Cleaved into: Cysteine protease ATG4D, mitochondrial]Atg4d Apg4d Autl4Q8BGV91
Cysteine-rich protein 1 (CRP-1) (Cysteine-rich intestinal protein) (CRIP)Crip1 CripP632541
Cysteine-rich secretory protein 1 (CRISP-1) (Acidic epididymal glycoprotein 1) (Sperm-coating glycoprotein 1) (SCP 1)Crisp1 Aeg-1 Aeg1Q034011
Cysteine-rich secretory protein LCCL domain-containing 2 (Coffeecrisp)Crispld2Q8BZQ21
Cystine/glutamate transporter (Amino acid transport system xc-) (Solute carrier family 7 member 11) (xCT)Slc7a11Q9WTR61
Cytochrome b ascorbate-dependent protein 3 (EC 1.-.-.-) (Cytochrome b561 family member A3) (Lysosomal cytochrome b) (LCytb)Cyb561a3 Cybasc3 LcytbQ6P1H11
Cytochrome b-c1 complex subunit 8 (Complex III subunit 8) (Complex III subunit VIII) (Ubiquinol-cytochrome c reductase complex 9.5 kDa protein) (Ubiquinol-cytochrome c reductase complex ubiquinone-binding protein QP-C)UqcrqQ9CQ691
Cytochrome b-c1 complex subunit Rieske, mitochondrial (EC 1.10.2.2) (Complex III subunit 5) (Cytochrome b-c1 complex subunit 5) (Rieske iron-sulfur protein) (RISP) (Ubiquinol-cytochrome c reductase iron-sulfur subunit) [Cleaved into: Cytochrome b-c1 complex subunit 11 (Complex III subunit IX) (Ubiquinol-cytochrome c reductase 8 kDa protein)]Uqcrfs1Q9CR681
Cytochrome b561 domain-containing protein 2 (Putative tumor suppressor protein 101F6)Cyb561d2 101f6Q9WUE31
Cytochrome c oxidase assembly factor 6 homologCoa6Q8BGD81
Cytochrome c oxidase subunit 6B2 (Cytochrome c oxidase subunit VIb isoform 2) (COX VIb-2) (Cytochrome c oxidase subunit VIb, testis-specific isoform)Cox6b2Q80ZN91
Cytochrome c oxidase subunit 8A, mitochondrial (Cytochrome c oxidase polypeptide VIII-liver) (Cytochrome c oxidase subunit 8-2)Cox8a Cox8 Cox8lQ644451
Cytochrome c oxidase subunit 8B, mitochondrial (Cytochrome c oxidase polypeptide VIII-heart) (Cytochrome c oxidase subunit 8-1) (Cytochrome c oxidase subunit 8H)Cox8b Cox8hP487721
Cytochrome P450 1A2 (EC 1.14.14.1) (CYPIA2) (Cytochrome P450-P2) (Cytochrome P450-P3)Cyp1a2 Cyp1a-2P001861
Cytochrome P450 1B1 (EC 1.14.14.1) (CYPIB1) (Cytochrome P450CMEF) (Cytochrome P450EF)Cyp1b1 Cyp1-b1Q644291
Cytochrome P450 20A1 (EC 1.14.-.-)Cyp20a1Q8BKE61
Cytochrome P450 2C70 (EC 1.14.14.1) (CYPIIC70)Cyp2c70 Cyp2c-70 Cyp2c22Q91W641
Cytochrome P450 2U1 (EC 1.14.14.1)Cyp2u1Q9CX981
Cytochrome P450 3A25 (EC 1.14.14.1) (CYPIIIA25)Cyp3a25O091581
Cytochrome P450 4V2 (EC 1.14.13.-)Cyp4v2 Cyp4v3Q9DBW01
Cytohesin-2 (PH, SEC7 and coiled-coil domain-containing protein 2) (CLM2) (SEC7 homolog B) (mSec7-2)Cyth2 Pscd2 Sec7bP630341
Cytohesin-4 (PH, SEC7 and coiled-coil domain-containing protein 4)Cyth4 Pscd4Q80YW01
Cytokine receptor common subunit gamma (Interleukin-2 receptor subunit gamma) (IL-2 receptor subunit gamma) (IL-2R subunit gamma) (IL-2RG) (gammaC) (p64) (CD antigen CD132)Il2rgP349021
Cytokine-inducible SH2-containing protein (CIS) (CIS-1) (Suppressor of cytokine signaling) (SOCS)Cish CisQ622251
Cytokine-like protein C17 (Protein Cytl1)Cytl1 4Cytl1A1E5L01
Cytoplasmic dynein 2 heavy chain 1 (Cytoplasmic dynein 2 heavy chain) (Dynein cytoplasmic heavy chain 2) (Dynein heavy chain 11) (mDHC11) (Dynein heavy chain isotype 1B)Dync2h1 Dhc1b Dnchc2 Kiaa1997Q45VK71
Cytoplasmic polyadenylation element-binding protein 2Cpeb2E9Q5X21
Cytoplasmic polyadenylation element-binding protein 3 (CPE-BP3) (CPE-binding protein 3) (mCPEB-3)Cpeb3 Kiaa0940Q7TN991
Cytoskeleton-associated protein 5Ckap5A2AGT51
Cytosolic endo-beta-N-acetylglucosaminidase (ENGase) (EC 3.2.1.96)EngaseQ8BX801
Cytosolic phospholipase A2 betaPla2g4bB7ZCM81
Cytospin-A (SPECC1-like protein) (Sperm antigen with calponin homology and coiled-coil domains 1-like)Specc1l Cytsa Kiaa0376Q2KN981
D site-binding protein (Albumin D box-binding protein) (Albumin D-element-binding protein)DbpQ609251
D-2-hydroxyglutarate dehydrogenase, mitochondrial (EC 1.1.99.-)D2hgdhQ8CIM31
D-aspartate oxidase (DASOX) (DDO) (EC 1.4.3.1)DdoQ922Z01
D-dopachrome decarboxylase (EC 4.1.1.84) (D-dopachrome tautomerase)DdtO352151
D-glucuronyl C5-epimerase (EC 5.1.3.17) (Heparan sulfate C5-epimerase) (Hsepi) (Heparin sulfate C5-epimerase) (Heparin/heparan sulfate:glucuronic acid C5-epimerase) (Heparosan-N-sulfate-glucuronate 5-epimerase)GlceQ9EPS31
D-tyrosyl-tRNA(Tyr) deacylase 1 (EC 3.1.-.-) (DNA-unwinding element-binding protein B) (DUE-B)Dtd1 Hars2Q9DD181
DALR anticodon-binding domain-containing protein 3Dalrd3Q6PJN81
DAZ-associated protein 1 (Deleted in azoospermia-associated protein 1)Dazap1Q9JII51
DCC-interacting protein 13-beta (Dip13-beta) (Adapter protein containing PH domain, PTB domain and leucine zipper motif 2)Appl2 Dip13b Dip3bQ8K3G91
DCN1-like protein 3 (DCUN1 domain-containing protein 3) (Defective in cullin neddylation protein 1-like protein 3)Dcun1d3Q8K0V21
DDB1- and CUL4-associated factor 11 (WD repeat-containing protein 23)Dcaf11 D14Ucla1 Wdr23Q91VU61
DDB1- and CUL4-associated factor 12-like protein 1 (WD repeat-containing protein 40B)Dcaf12l1 Wdr40bQ8CBW41
DDB1- and CUL4-associated factor 13 (WD repeat and SOF domain-containing protein 1)Dcaf13 Gm83 Wdsof1Q6PAC31
DDB1- and CUL4-associated factor 6 (IQ motif and WD repeat-containing protein 1) (Nuclear receptor interaction protein) (NRIP)Dcaf6 Iqwd1Q9DC221
DDRGK domain-containing protein 1Ddrgk1Q80WW91
DEAH (Asp-Glu-Ala-His) box polypeptide 38 (Protein Dhx38)Dhx38Q80X981
Death domain-associated protein 6 (Daxx)DaxxO356131
Death domain-containing membrane protein NRADD (Neurotrophin receptor homolog-2) (NRH2) (Neurotrophin receptor-alike death domain protein)NraddQ8CJ261
Death effector domain-containing protein (DEDPro1)DeddQ9Z1L31
Death-associated protein kinase 1 (DAP kinase 1) (EC 2.7.11.1)Dapk1Q80YE71
Death-associated protein kinase 2 (DAP kinase 2) (EC 2.7.11.1) (DAP-kinase-related protein 1) (DRP-1)Dapk2Q8VDF31
Dedicator of cytokinesis protein 5 (Lens rupture protein 2) (Rupture of lens cataract protein)Dock5 Lr2 RlcB2RY041
Deformed epidermal autoregulatory factor 1 homolog (Nuclear DEAF-1-related transcriptional regulator) (NUDR)Deaf1Q9Z1T51
Dehydrogenase/reductase member 2 (Protein Dhrs2)Dhrs2 mCG_22493Q149L01
Dehydrogenase/reductase SDR family member 7B (EC 1.1.-.-)Dhrs7bQ99J471
Delta(14)-sterol reductase (Delta-14-SR) (EC 1.3.1.70) (C-14 sterol reductase) (C14SR) (Sterol C14-reductase) (Transmembrane 7 superfamily member 2)Tm7sf2Q71KT51
Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial (EC 5.3.3.-)Ech1O354591
Density-regulated protein (DRP)DenrQ9CQJ61
Deoxyguanosine kinase, mitochondrial (dGK) (EC 2.7.1.113)Dguok DgkQ9QX601
Deoxyhypusine hydroxylase (DOHH) (EC 1.14.99.29) (Deoxyhypusine dioxygenase) (Deoxyhypusine monooxygenase)DohhQ99LN91
Deoxyhypusine synthase (DHS) (EC 2.5.1.46)DhpsQ3TXU51
Deoxyribonuclease-2-alpha (EC 3.1.22.1) (Acid DNase) (Deoxyribonuclease II alpha) (DNase II alpha) (Lysosomal DNase II)Dnase2 Dnase2a Dnl2P565421
DEP domain-containing protein 5Depdc5 Kiaa0645P614601
Derlin-2 (Degradation in endoplasmic reticulum protein 2) (Der1-like protein 2) (F-LANa)Derl2 Der2 FlanaQ8BNI41
Dermatan-sulfate epimerase (DS epimerase) (EC 5.1.3.19) (Chondroitin-glucuronate 5-epimerase) (Squamous cell carcinoma antigen recognized by T-cells 2) (SART-2)Dse Sart2Q8BLI41
Developmentally-regulated GTP-binding protein 1 (DRG-1) (Neural precursor cell expressed developmentally down-regulated protein 3) (NEDD-3)Drg1 Drg Nedd-3 Nedd3P322331
Dexamethasone-induced protein (Protein MYLE)Dexi MyleQ9WUQ71
Dexamethasone-induced Ras-related protein 1Rasd1 Dexras1O356261
Diacylglycerol kinase beta (DAG kinase beta) (EC 2.7.1.107) (Diglyceride kinase beta) (DGK-beta)Dgkb Kiaa0718Q6NS521
Diacylglycerol kinase theta (DAG kinase theta) (EC 2.7.1.107) (Diglyceride kinase theta) (DGK-theta)DgkqQ6P5E81
Diamine acetyltransferase 2 (EC 2.3.1.57) (Polyamine N-acetyltransferase 2) (Spermidine/spermine N(1)-acetyltransferase 2)Sat2 Ssat2Q6P8J21
Dihydroorotate dehydrogenase (quinone), mitochondrial (DHOdehase) (EC 1.3.5.2) (Dihydroorotate oxidase)DhodhO354351
Dimethylaniline monooxygenase [N-oxide-forming] 2 (EC 1.14.13.8) (Dimethylaniline oxidase 2) (Pulmonary flavin-containing monooxygenase 2) (FMO 2)Fmo2Q8K2I31
Dimethylaniline monooxygenase [N-oxide-forming] 5 (EC 1.14.13.8) (Dimethylaniline oxidase 5) (Hepatic flavin-containing monooxygenase 5) (FMO 5)Fmo5P978721
Dipeptidase 1 (EC 3.4.13.19) (Membrane-bound dipeptidase 1) (MBD-1) (Microsomal dipeptidase) (Renal dipeptidase)Dpep1 Mbd1 RdpP314281
Dipeptidyl peptidase 1 (EC 3.4.14.1) (Cathepsin C) (Cathepsin J) (Dipeptidyl peptidase I) (DPP-I) (DPPI) (Dipeptidyl transferase) [Cleaved into: Dipeptidyl peptidase 1 exclusion domain chain (Dipeptidyl peptidase I exclusion domain chain); Dipeptidyl peptidase 1 heavy chain (Dipeptidyl peptidase I heavy chain); Dipeptidyl peptidase 1 light chain (Dipeptidyl peptidase I light chain)]CtscP978211
Dipeptidyl peptidase 2 (EC 3.4.14.2) (Dipeptidyl aminopeptidase II) (Dipeptidyl peptidase 7) (Dipeptidyl peptidase II) (DPP II) (Quiescent cell proline dipeptidase)Dpp7 Dpp2 QppQ9ET221
Diphthine--ammonia ligase (EC 6.3.1.14) (ATP-binding domain-containing protein 4) (Diphthamide synthase) (Diphthamide synthetase) (Protein DPH6 homolog)Dph6 Atpbd4Q9CQ281
Disabled homolog 2-interacting protein (DAB2-interacting protein) (ASK-interacting protein 1) (DOC-2/DAB-2 interactive protein)Dab2ip Kiaa1743Q3UHC71
Discoidin domain-containing receptor 2 (Discoidin domain receptor 2) (EC 2.7.10.1) (CD167 antigen-like family member B) (Neurotrophic tyrosine kinase, receptor-related 3) (Receptor protein-tyrosine kinase TKT) (Tyrosine-protein kinase TYRO10) (CD antigen CD167b)Ddr2 Ntrkr3 Tkt Tyro10Q623711
Disintegrin and metalloproteinase domain-containing protein 10 (ADAM 10) (EC 3.4.24.81) (Kuzbanian protein homolog) (Mammalian disintegrin-metalloprotease) (CD antigen CD156c)Adam10 Kuz MadmO355981
Disintegrin and metalloproteinase domain-containing protein 32 (ADAM 32)Adam32Q8K4101
Disintegrin and metalloproteinase domain-containing protein 9 (ADAM 9) (EC 3.4.24.-) (Meltrin-gamma) (Metalloprotease/disintegrin/cysteine-rich protein 9) (Myeloma cell metalloproteinase)Adam9 Kiaa0021 Mdc9 MltngQ610721
Disks large homolog 1 (Embryo-dlg/synapse-associated protein 97) (E-dlg/SAP97) (Synapse-associated protein 97) (SAP-97) (SAP97)Dlg1 Dlgh1Q811D01
Disks large-associated protein 4 (DAP-4) (PSD-95/SAP90-binding protein 4) (SAP90/PSD-95-associated protein 4) (SAPAP-4)Dlgap4 Kiaa0964 Sapap4B1AZP21
DmX-like protein 2Dmxl2B0V2P51
DNA damage-binding protein 1 (DDB p127 subunit) (Damage-specific DNA-binding protein 1) (UV-damaged DNA-binding factor)Ddb1Q3U1J41
DNA endonuclease RBBP8 (EC 3.1.-.-) (CtBP-interacting protein) (CtIP) (Retinoblastoma-binding protein 8) (RBBP-8) (Retinoblastoma-interacting protein and myosin-like) (RIM) (Sporulation in the absence of SPO11 protein 2 homolog) (SAE2)Rbbp8 CtipQ80YR61
DNA excision repair protein ERCC-8 (Cockayne syndrome WD repeat protein CSA homolog)Ercc8 Ckn1 CsaQ8CFD51
DNA fragmentation factor subunit alpha (DNA fragmentation factor 45 kDa subunit) (DFF-45) (Inhibitor of CAD) (ICAD)Dffa IcadO547861
DNA helicase INO80 (EC 3.6.4.12) (INO80 complex subunit A) (Putative DNA helicase INO80 complex homolog 1)Ino80 Inoc1 Kiaa1259Q6ZPV21
DNA ligase 1 (EC 6.5.1.1) (DNA ligase I) (Polydeoxyribonucleotide synthase [ATP] 1)Lig1 Lig-1P379131
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