EVpedia provide top 100+ EV markers, selected according to their identification number.
Based on EV proteomes, we defined the identification number of protein A as the number of datasets which contain protein A.
Therefore, proteins with higher identification numbers were more conserved.

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Protein name Gene symbol UniProt accession Identification number
ELKS/Rab6-interacting/CAST family member 1 (ERC-1) (CAZ-associated structural protein 2) (CAST2) (Rab6-interacting protein 2)Erc1 Cast2 Kiaa1081 Rab6ip2Q99MI11
ELL-associated factor 1Eaf1Q9D4C51
ELL-associated factor 2 (Ehrlich S-II transcriptional activator factor) (Testosterone-regulated apoptosis inducer and tumor suppressor protein)Eaf2 Festa TraitsQ91ZD61
Elongation factor G, mitochondrial (EF-Gmt) (Elongation factor G 1, mitochondrial) (mEF-G 1) (Elongation factor G1)Gfm1 Efg Efg1 GfmQ8K0D51
Elongation of very long chain fatty acids protein 1 (EC 2.3.1.199) (3-keto acyl-CoA synthase Elovl1) (ELOVL fatty acid elongase 1) (ELOVL FA elongase 1) (Very-long-chain 3-oxoacyl-CoA synthase 1)Elovl1 Ssc1Q9JLJ51
Elongation of very long chain fatty acids protein 6 (EC 2.3.1.199) (3-keto acyl-CoA synthase Elovl6) (ELOVL fatty acid elongase 6) (ELOVL FA elongase 6) (Fatty acyl-CoA elongase) (Long chain fatty acid elongase) (Myelin-associated SUR4 protein) (Very-long-chain 3-oxoacyl-CoA synthase 6)Elovl6 Face Lce MasrQ920L51
Elongator complex protein 1 (ELP1) (IkappaB kinase complex-associated protein) (IKK complex-associated protein)Ikbkap Elp1 IkapQ7TT371
Elongator complex protein 4 (PAX6 neighbor gene protein)Elp4 PaxnebQ9ER731
Embigin (Teratocarcinoma glycoprotein Gp-70)Emb Gp70P219951
EnamelinEnamO551961
Endonuclease/exonuclease/phosphatase family domain-containing protein 1Eepd1 Kiaa1706Q3TGW21
Endophilin-A2 (Endophilin-2) (SH3 domain protein 2B) (SH3 domain-containing GRB2-like protein 1) (SH3p8)Sh3gl1 Sh3d2bQ624191
Endophilin-B1 (SH3 domain-containing GRB2-like protein B1)Sh3glb1 Kiaa0491Q9JK481
Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase (EC 3.2.1.113) (ER alpha-1,2-mannosidase) (ER mannosidase 1) (ERMan1) (Man9GlcNAc2-specific-processing alpha-mannosidase) (Mannosidase alpha class 1B member 1)Man1b1A2AJ151
Endothelial lipase (EC 3.1.1.3) (Endothelial cell-derived lipase) (EDL)LipgQ9WVG51
Endothelin-1 receptor (Endothelin A receptor) (ET-A) (ET-AR)Ednra Gpcr10Q616141
Endothelin-converting enzyme-like 1 (EC 3.4.24.-) (Damage-induced neuronal endopeptidase) (Xce protein)Ecel1 Dine XceQ9JMI01
Enhancer of mRNA-decapping protein 4Edc4Q3UJB91
Enhancer of rudimentary homolog (Mer)ErhP840891
Enoyl-CoA hydratase domain-containing protein 3, mitochondrialEchdc3Q9D7J91
Eosinophil cationic protein 2 (ECP 2) (EC 3.1.27.-) (Eosinophil secondary granule ribonuclease 2) (EAR-2) (Ribonuclease 3-2) (RNase 3-2)Ear2 Rnase2P974251
Eosinophil peroxidase (EPO) (EC 1.11.1.7) [Cleaved into: Eosinophil peroxidase light chain; Eosinophil peroxidase heavy chain]Epx EperP492901
Eph receptor B2 (Ephrin type-B receptor 2)Ephb2A3KG011
Ephrin type-A receptor 1 (mEpha1) (EC 2.7.10.1) (Embryonic stem cell kinase) (Tyrosine-protein kinase receptor ESK)Epha1 EskQ607501
Ephrin type-A receptor 5 (EC 2.7.10.1) (Brain-specific kinase) (CEK-7) (EPH homology kinase 1) (EHK-1)Epha5 Bsk Ehk1Q606291
Epidermal growth factor receptor kinase substrate 8-like protein 2 (EPS8-like protein 2) (Epidermal growth factor receptor pathway substrate 8-related protein 2) (EPS8-related protein 2)Eps8l2 Eps8r2Q99K301
Epidermal growth factor-binding protein type B (EGF-BP B) (EC 3.4.21.119) (Glandular kallikrein K13) (mGK-13) (Prorenin-converting enzyme 1) (PRECE-1) (Tissue kallikrein 13)Egfbp2 Egfbp-2 Klk-13 Klk13P363681
Epidermal growth factor-binding protein type B (Glandular kallikrein KLK13)Klk13 Egfbp2Q8CGR61
Epididymis-specific alpha-mannosidase (EC 3.2.1.24) (Mannosidase alpha class 2B member 2)Man2b2 Kiaa0935O547821
Epiphycan (Dermatan sulfate proteoglycan 3) (Proteoglycan-Lb) (PG-Lb) (Small chondroitin/dermatan sulfate proteoglycan)Epyc Dspg3 PglbP701861
Epithelial cell adhesion molecule (Ep-CAM) (Epithelial glycoprotein 314) (EGP314) (mEGP314) (Protein 289A) (Tumor-associated calcium signal transducer 1) (CD antigen CD326)Epcam Tacstd1Q99JW51
Epithelial membrane protein 1 (EMP-1) (Tumor-associated membrane protein)Emp1 TmpP478011
Epithelial membrane protein 2 (EMP-2) (Protein XMP)Emp2 XmpO886621
Epoxide hydrolase 4 (EC 3.3.-.-) (Abhydrolase domain-containing protein 7) (Epoxide hydrolase-related protein)Ephx4 Abhd7 EphxrpQ6IE261
Equilibrative nucleoside transporter 2 (36 kDa hydrophobic nucleolar protein) (36 kDa nucleolar protein HNP36) (Delayed-early response protein 12) (Equilibrative nitrobenzylmercaptopurine riboside-insensitive nucleoside transporter) (Equilibrative NBMPR-insensitive nucleoside transporter) (Nucleoside transporter, ei-type) (Solute carrier family 29 member 2)Slc29a2 Der12 Ent2 Hnp36Q616721
ER degradation enhancer, mannosidase alpha-like 2 (Protein Edem2)Edem2 mCG_21080Q8BJT91
ER degradation-enhancing alpha-mannosidase-like protein 3 (EC 3.2.1.113) (Alpha-1,2-mannosidase EDEM3)Edem3Q2HXL61
ER lumen protein retaining receptor 1 (KDEL endoplasmic reticulum protein retention receptor 1) (KDEL receptor 1)Kdelr1Q99JH81
ER membrane protein complex subunit 1Emc1 Kiaa0090Q8C7X21
ER membrane protein complex subunit 6 (Transmembrane protein 93)Emc6 Tmem93Q9CQW01
ER membrane protein complex subunit 8 (Neighbor of COX4)Emc8 Cox4al Cox4nb Noc4O703781
ER membrane protein complex subunit 9 (Protein FAM158A)Emc9 Cgi112 Fam158aQ9DB761
Erlin-1 (Endoplasmic reticulum lipid raft-associated protein 1) (Protein KE04 homolog) (Stomatin-prohibitin-flotillin-HflC/K domain-containing protein 1) (SPFH domain-containing protein 1)Erlin1 Keo4 Spfh1Q91X781
Ethylmalonyl-CoA decarboxylase (EC 4.1.1.94) (Enoyl-CoA hydratase domain-containing protein 1) (Methylmalonyl-CoA decarboxylase) (MMCD) (EC 4.1.1.41)Echdc1Q9D9V31
ETS homologous factor (ETS domain-containing transcription factor)EhfO702731
ETS-related transcription factor Elf-1 (E74-like factor 1)Elf1Q607751
Eukaryotic elongation factor 2 kinase (eEF-2 kinase) (eEF-2K) (EC 2.7.11.20) (Calcium/calmodulin-dependent eukaryotic elongation factor 2 kinase)Eef2kO087961
Eukaryotic translation initiation factor 2-alpha kinase 1 (EC 2.7.11.1) (Heme-controlled repressor) (HCR) (Heme-regulated eukaryotic initiation factor eIF-2-alpha kinase) (Heme-regulated inhibitor) (Hemin-sensitive initiation factor 2-alpha kinase)Eif2ak1 HriQ9Z2R91
Eukaryotic translation initiation factor 2-alpha kinase 3Eif2ak3E9QQ301
Eukaryotic translation initiation factor 2-alpha kinase 4 (EC 2.7.11.1) (GCN2-like protein) (mGCN2)Eif2ak4 Gcn2 Kiaa1338Q9QZ051
Eukaryotic translation initiation factor 4 gamma 1 (eIF-4-gamma 1) (eIF-4G 1) (eIF-4G1)Eif4g1Q6NZJ61
Eukaryotic translation initiation factor 4E type 3 (eIF-4E type 3) (eIF-4E3) (eIF4E type 3) (eIF4E-3)Eif4e3Q9DBB51
Exocyst complex component 1Exoc1 Sec3l1Q6P1Y91
Exocyst complex component 5 (Exocyst complex component Sec10)Exoc5 Sec10l1Q3TPX41
Exocyst complex component 6B (Exocyst complex component Sec15B) (SEC15-like protein 2)Exoc6b Sec15b Sec15l2A6H5Z31
Exocyst complex component 8 (Exocyst complex 84 kDa subunit)Exoc8Q6PGF71
Exosome complex component MTR3 (Exosome component 6) (mRNA transport regulator 3 homolog)Exosc6 Mtr3Q8BTW31
Exosome complex component RRP4 (Exosome component 2) (Ribosomal RNA-processing protein 4)Exosc2 Rrp4Q8VBV31
Exosome complex component RRP41 (Exosome component 4) (Ribosomal RNA-processing protein 41)Exosc4 Rrp41Q921I91
Exosome complex component RRP45 (Autoantigen PM/Scl 1) (Exosome component 9) (P75 polymyositis-scleroderma overlap syndrome-associated autoantigen) (Polymyositis/scleroderma autoantigen 1) (Polymyositis/scleroderma autoantigen 75 kDa) (PM/Scl-75)Exosc9 Pmscl1Q9JHI71
Exosome complex exonuclease RRP42 (Exosome component 7) (Ribosomal RNA-processing protein 42)Exosc7 Rrp42Q9D0M01
Exosome complex exonuclease RRP44 (EC 3.1.13.-) (EC 3.1.26.-) (Protein DIS3 homolog) (Ribosomal RNA-processing protein 44)Dis3 Kiaa1008 Rrp44Q9CSH31
Exosome component 10 (EC 3.1.13.-) (Autoantigen PM/Scl 2 homolog) (Polymyositis/scleroderma autoantigen 2 homolog)Exosc10 Pmscl2P569601
Exostosin-1 (EC 2.4.1.224) (EC 2.4.1.225) (Glucuronosyl-N-acetylglucosaminyl-proteoglycan/N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase) (Multiple exostoses protein 1 homolog)Ext1P974641
Exostosin-2 (EC 2.4.1.224) (EC 2.4.1.225) (Glucuronosyl-N-acetylglucosaminyl-proteoglycan/N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase) (Multiple exostoses protein 2 homolog)Ext2P704281
Exportin-1 (Exp1) (Chromosome region maintenance 1 protein homolog)Xpo1 Crm1Q6P5F91
Exportin-2 (Exp2) (Chromosome segregation 1-like protein) (Importin-alpha re-exporter)Cse1l Xpo2Q9ERK41
Expressed sequence AA792892 (Protein AA792892)AA792892Q8C6S11
Expressed sequence AI894139 (Protein Zfp956)Zfp956 AI894139 mCG_140816Q3UZY61
Extracellular matrix protein 1 (Secretory component p85)Ecm1Q615081
F-actin-capping protein subunit alpha-1 (CapZ alpha-1)Capza1 Cappa1P477531
F-actin-capping protein subunit alpha-2 (CapZ alpha-2)Capza2 Cappa2P477541
F-box only protein 18 (EC 3.6.4.12) (F-box DNA helicase 1)Fbxo18 Fbh1 Fbx18Q8K2I91
F-box only protein 21Fbxo21 Fbx21 Kiaa0875Q8VDH11
F-box only protein 25Fbxo25 Fbx25Q9D2Y61
F-box only protein 28Fbxo28 D1Ertd578e Kiaa0483Q8BIG41
F-box only protein 3Fbxo3 Fba Fbx3Q9DC631
F-box only protein 38 (Modulator of KLF7 activity) (MoKA)Fbxo38Q8BMI01
F-box only protein 44 (F-box only protein 6a)Fbxo44 Fbxo6aQ8BK261
F-box only protein 7Fbxo7Q3U7U31
F-box only protein 9Fbxo9 MNCb-2471Q8BK061
F-box-like/WD repeat-containing protein TBL1X (Transducin beta-like protein 1X)Tbl1x Tbl1Q9QXE71
F-box/LRR-repeat protein 17 (F-box and leucine-rich repeat protein 17) (F-box only protein 13)Fbxl17 Fbl17 Fbx13 Fbxo13Q9QZN11
F-box/LRR-repeat protein 20 (F-box and leucine-rich repeat protein 20) (F-box/LRR-repeat protein 2-like)Fbxl20 Fbl2Q9CZV81
F-box/LRR-repeat protein 3 (F-box and leucine-rich repeat protein 3A) (F-box/LRR-repeat protein 3A) (Protein after-hours) (Protein overtime)Fbxl3 Afh Fbl3a Fbxl3a OvtmQ8C4V41
F-box/LRR-repeat protein 4 (F-box and leucine-rich repeat protein 4)Fbxl4Q8BH701
F-box/LRR-repeat protein 6 (F-box and leucine-rich repeat protein 6) (F-box protein FBL6)Fbxl6 Fbl6 MNCb-1275Q9QXW01
F-box/WD repeat-containing protein 7 (F-box and WD-40 domain-containing protein 7) (F-box protein FBW7) (F-box protein Fbxw6) (F-box-WD40 repeat protein 6) (SEL-10)Fbxw7 Fbw7 Fbwd6 Fbxw6Q8VBV41
FACT complex subunit SSRP1 (Facilitates chromatin transcription complex subunit SSRP1) (Recombination signal sequence recognition protein 1) (Structure-specific recognition protein 1) (T160)Ssrp1Q089431
FAD synthase (EC 2.7.7.2) (FAD pyrophosphorylase) (FMN adenylyltransferase) (Flavin adenine dinucleotide synthase) [Includes: Molybdenum cofactor biosynthesis protein-like region; FAD synthase region]Flad1Q8R1231
FAD-dependent oxidoreductase domain-containing protein 2Foxred2 D15Bwg0759eQ3USW51
Fanconi anemia group G protein homolog (Protein FACG)FancgQ9EQR61
Fanconi anemia-associated protein of 100 kDaFaap100A2ACJ21
Fanconi anemia-associated protein of 20 kDaFaap20Q3UN581
Far upstream element-binding protein 1Fubp1Q3TUE11
Far upstream element-binding protein 2 (FUSE-binding protein 2) (KH type-splicing regulatory protein) (KSRP)Khsrp Fubp2Q3U0V11
FAS-associated factor 1Faf1P547311
Fatty acid desaturase 6 (EC 1.14.19.-)Fads6Q80UG11
Fatty acyl-CoA reductase 2 (EC 1.2.1.n2) (Male sterility domain-containing protein 1)Far2 Mlstd1Q7TNT21
Fatty aldehyde dehydrogenase (EC 1.2.1.3) (Aldehyde dehydrogenase 3) (Aldehyde dehydrogenase family 3 member A2)Aldh3a2 Ahd-3 Ahd3 Aldh3 Aldh4P477401
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