EVpedia provide top 100+ EV markers, selected according to their identification number.
Based on EV proteomes, we defined the identification number of protein A as the number of datasets which contain protein A.
Therefore, proteins with higher identification numbers were more conserved.

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Protein name Gene symbol UniProt accession Identification number
General transcription factor IIH subunit 5 (General transcription factor IIH polypeptide 5) (TFB5 ortholog) (TFIIH basal transcription factor complex TTD-A subunit)Gtf2h5 D17Wsu155eQ8K2X81
Germ cell-specific gene 1 protein (Germ cell-associated protein 1)Gsg1Q8R1W21
GH3 domain-containing proteinGhdc D11lgp1e Lgp1Q99J231
Glia-derived nexin (GDN) (Peptidase inhibitor 7) (PI-7) (Protease nexin 1) (PN-1) (Protease nexin I) (Serine protease-inhibitor 4) (Serpin E2)Serpine2 Pi7 Pn1 Spi4Q072351
GLIPR1-like protein 2Glipr1l2Q9CQ351
Glucokinase (EC 2.7.1.2) (Hexokinase type IV) (HK IV) (Hexokinase-4) (HK4) (Hexokinase-D)Gck GkP527921
Glucosamine-6-phosphate isomerase 2 (EC 3.5.99.6) (Glucosamine-6-phosphate deaminase 2) (GNPDA 2) (GlcN6P deaminase 2)Gnpda2 Kiaa4008Q9CRC91
Glucose-fructose oxidoreductase domain-containing protein 1 (EC 1.-.-.-)Gfod1Q3UHD21
Glucosidase 2 subunit beta (80K-H protein) (Glucosidase II subunit beta) (Protein kinase C substrate 60.1 kDa protein heavy chain) (PKCSH)PrkcshO087951
Glucosylceramidase (EC 3.2.1.45) (Acid beta-glucosidase) (Beta-glucocerebrosidase) (D-glucosyl-N-acylsphingosine glucohydrolase)GbaP174391
Glutamate decarboxylase 2 (EC 4.1.1.15) (65 kDa glutamic acid decarboxylase) (GAD-65) (Glutamate decarboxylase 65 kDa isoform)Gad2 Gad65P483201
Glutamate receptor ionotropic, kainate 3 (GluK3) (Glutamate receptor 7) (GluR-7) (GluR7)Grik3 Glur7B1AS291
Glutamate receptor ionotropic, kainate 4 (GluK4)Grik4Q8BMF51
Glutamate receptor ionotropic, NMDA 2A (GluN2A) (Glutamate [NMDA] receptor subunit epsilon-1) (N-methyl D-aspartate receptor subtype 2A) (NMDAR2A) (NR2A)Grin2aP354361
Glutamate receptor ionotropic, NMDA 2D (GluN2D) (Glutamate [NMDA] receptor subunit epsilon-4) (N-methyl D-aspartate receptor subtype 2D) (NMDAR2D) (NR2D)Grin2d GluN2DQ033911
Glutaminase liver isoform, mitochondrial (GLS) (EC 3.5.1.2) (L-glutaminase) (L-glutamine amidohydrolase)Gls2 Kiaa4146Q571F81
Glutamyl-tRNA(Gln) amidotransferase subunit A, mitochondrial (Glu-AdT subunit A) (EC 6.3.5.-) (Glutaminyl-tRNA synthase-like protein 1)Qrsl1Q9CZN81
Glutamyl-tRNA(Gln) amidotransferase subunit B, mitochondrial (Glu-AdT subunit B) (EC 6.3.5.-) (Cytochrome c oxidase assembly factor PET112 homolog)Pet112 Pet112lQ99JT11
Glutaredoxin-1 (Thioltransferase-1) (TTase-1)Glrx Glrx1 Grx Grx1Q9QUH01
Glutaryl-CoA dehydrogenase, mitochondrial (GCD) (EC 1.3.8.6)GcdhQ607591
Glutathione peroxidase 1 (GPx-1) (GSHPx-1) (EC 1.11.1.9) (Cellular glutathione peroxidase) (Selenium-dependent glutathione peroxidase 1)Gpx1P113521
Glutathione S-transferase C-terminal domain-containing proteinGstcdQ5RL511
Glutathione S-transferase kappa 1 (EC 2.5.1.18) (GST 13-13) (GST class-kappa) (GSTK1-1) (mGSTK1) (Glutathione S-transferase subunit 13)Gstk1Q9DCM21
Glutathione S-transferase Mu 3 (EC 2.5.1.18) (GST class-mu 3) (Glutathione S-transferase GT9.3)Gstm3P196391
Glutathione S-transferase omega-2 (GSTO-2) (EC 2.5.1.18) (Glutathione S-transferase omega 2-2) (GSTO 2-2) (Glutathione-dependent dehydroascorbate reductase) (EC 1.8.5.1) (Monomethylarsonic acid reductase) (MMA(V) reductase) (EC 1.20.4.2)Gsto2Q8K2Q21
Glutathione synthetase (GSH synthetase) (GSH-S) (EC 6.3.2.3) (Glutathione synthase)GssP518551
Glycerol-3-phosphate dehydrogenase 1-like protein (EC 1.1.1.8)Gpd1l Kiaa0089Q3ULJ01
Glycine dehydrogenase [decarboxylating], mitochondrial (EC 1.4.4.2) (Glycine cleavage system P protein) (Glycine decarboxylase)GldcQ91W431
Glycine receptor subunit beta (Glycine receptor 58 kDa subunit)GlrbP481681
Glycogen phosphorylase, liver form (EC 2.4.1.1)PyglQ9ET011
Glycogen synthase kinase-3 alpha (GSK-3 alpha) (EC 2.7.11.26) (Serine/threonine-protein kinase GSK3A) (EC 2.7.11.1)Gsk3aQ2NL511
Glycogen synthase kinase-3 beta (GSK-3 beta) (EC 2.7.11.26) (Serine/threonine-protein kinase GSK3B) (EC 2.7.11.1)Gsk3bQ9WV601
Glycogen [starch] synthase, liver (EC 2.4.1.11)Gys2Q8VCB31
Glycophorin-C (CD antigen CD236)GypcQ78HU71
Glycosaminoglycan xylosylkinase (EC 2.7.1.-) (Protein FAM20B) (Xylose kinase)Fam20bQ8VCS31
Glycosylphosphatidylinositol anchor attachment 1 protein (GPI anchor attachment protein 1) (GAA1 protein homolog) (mGAA1)Gpaa1 Gaa1Q9WTK31
Glycosyltransferase 8 domain-containing protein 2 (EC 2.4.1.-)Glt8d2Q640P41
Glyoxalase domain-containing protein 4Glod4Q9CPV41
Glyoxylate reductase/hydroxypyruvate reductase (EC 1.1.1.79) (EC 1.1.1.81)Grhpr GlxrQ91Z531
Glypican-1 [Cleaved into: Secreted glypican-1]Gpc1Q9QZF21
Glypican-5 [Cleaved into: Secreted glypican-5]Gpc5Q8CAL51
Glypican-6 [Cleaved into: Secreted glypican-6]Gpc6Q9R0871
GMP reductase 1 (EC 1.7.1.7) (Guanosine 5'-monophosphate oxidoreductase 1) (Guanosine monophosphate reductase 1)Gmpr Gmpr1Q9DCZ11
GPI-anchor transamidase (GPI transamidase) (EC 3.-.-.-) (Phosphatidylinositol-glycan biosynthesis class K protein) (PIG-K)PigkQ9CXY91
GPI-linked NAD(P)(+)--arginine ADP-ribosyltransferase 1 (EC 2.4.2.31) (ADP-ribosyltransferase C2 and C3 toxin-like 1) (ARTC1) (Mono(ADP-ribosyl)transferase 1) (YAC-1) (CD antigen CD296)Art1 Art2Q609351
GPR155 variant 5 (Protein Gpr155)Gpr155A2AWR21
GRAM domain-containing protein 4 (Death-inducing protein)Gramd4 Dip Kiaa0767Q8CB441
GranulinsGrnQ3U9N41
Granulocyte-macrophage colony-stimulating factor receptor subunit alpha (GM-CSF-R-alpha) (GMCSFR-alpha) (GMR-alpha) (CD antigen CD116)Csf2ra CsfgmraQ009411
Gremlin-2 (Cysteine knot superfamily 1, BMP antagonist 2) (Protein related to DAN and cerberus)Grem2 Cktsf1b2 PrdcO882731
GRIP and coiled-coil domain-containing protein 1 (Golgi coiled-coil protein 1)Gcc1Q9D4H21
Group XV phospholipase A2 (EC 2.3.1.-) (1-O-acylceramide synthase) (ACS) (LCAT-like lysophospholipase) (LLPL) (Lysophospholipase 3) (Lysosomal phospholipase A2) (LPLA2)Pla2g15 Lypla3Q8VEB41
Growth arrest and DNA damage-inducible proteins-interacting protein 1 (39S ribosomal protein L59, mitochondrial) (MRP-L59)Gadd45gip1 Mrpl59Q9CR591
Growth arrest-specific protein 6 (GAS-6) (AXL receptor tyrosine kinase ligand)Gas6Q615921
Growth arrest-specific protein 8 (GAS-8) (Growth arrest-specific protein 11) (GAS-11)Gas8 Gas11Q607791
Growth hormone-inducible transmembrane protein (Mitochondrial morphology and cristae structure 1) (MICS1)Ghitm Mics1Q91VC91
Growth/differentiation factor 5 (GDF-5)Gdf5 Bp Gdf-5P430271
GrpE protein homolog 2, mitochondrial (Mt-GrpE#2)Grpel2 Mt-grpel2O883961
GSK-3-binding protein FRAT2 (Frequently rearranged in advanced T-cell lymphomas 2) (FRAT-2)Frat2Q8K0251
GTP-binding nuclear protein Ran, testis-specific isoformRasl2-9Q618201
GTP-binding protein Di-Ras2 (Distinct subgroup of the Ras family member 2)Diras2Q5PR731
GTPase HRas (H-Ras-1) (Transforming protein p21) (c-H-ras) (p21ras) [Cleaved into: GTPase HRas, N-terminally processed]Hras1 HrasQ614111
GTPase IMAP family member 1 (GTPase, IMAP family member 1)Gimap1Q3TFI61
GTPase-activating Rap/Ran-GAP domain-like protein 3Garnl3Q3V0G71
Guanine nucleotide-binding protein G(i) subunit alpha-1 (Adenylate cyclase-inhibiting G alpha protein)Gnai1 Gnai-1B2RSH21
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10Gng10Q9CXP81
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11Gng11 Gngt11P619531
Guanine nucleotide-binding protein G(k) subunit alpha (G(i) alpha-3)Gnai3Q9DC511
Guanine nucleotide-binding protein G(o) subunit alphaGnao1 Gna0 GnaoP188721
Guanine nucleotide-binding protein subunit beta-5 (Gbeta5) (Transducin beta chain 5)Gnb5P628811
Guanylyl cyclase GC-E (EC 4.6.1.2) (Guanylate cyclase 2E)Gucy2e Guc2eP527851
H/ACA ribonucleoprotein complex non-core subunit NAF1Naf1Q3UMQ81
H1 histone family, member X (Protein H1fx)H1fxQ80ZM51
Haloacid dehalogenase-like hydrolase domain-containing protein 3Hdhd3Q9CYW41
HAUS augmin-like complex subunit 7 (26S proteasome-associated UCH37-interacting protein 1) (UCHL5-interacting protein)Haus7 Uchl5ip Uip1Q8BKT81
HAUS augmin-like complex subunit 8 (HEC1/NDC80-interacting centrosome-associated protein 1) (Sarcoma antigen NY-SAR-48 homolog)Haus8 Hice1Q99L001
HCLS1-binding protein 3 (HS1-binding protein 3) (HSP1BP-3)Hs1bp3Q3TC931
Heart- and neural crest derivatives-expressed protein 2 (Deciduum, heart, autonomic nervous system and neural crest derivatives-expressed protein 2) (dHAND) (Helix-loop-helix transcription factor expressed in embryo and deciduum) (Thing-2)Hand2 Dhand Hed Thing2Q610391
HEAT repeat-containing protein 5AHeatr5a Kiaa1316Q5PRF01
HEAT repeat-containing protein 5BHeatr5b Kiaa1414Q8C5471
Heat shock 70 kDa protein 4L (Heat shock 70-related protein APG-1) (Osmotic stress protein 94)Hspa4l Apg1 Hsp4l Osp94P487221
Heat shock protein 105 kDa (42 degrees C-HSP) (Heat shock 110 kDa protein) (Heat shock-related 100 kDa protein E7I) (HSP-E7I)Hsph1 Hsp105 Hsp110 Kiaa0201Q616991
Heat shock protein beta-2 (HspB2)Hspb2Q99PR81
Heat-stable enterotoxin receptor (STA receptor) (EC 4.6.1.2) (Guanylyl cyclase C) (GC-C) (Intestinal guanylate cyclase)Gucy2c Guc2cQ3UWA61
Helix-loop-helix protein 1 (HEN-1) (Nescient helix loop helix 1) (NSCL-1)Nhlh1 Hen1Q025761
Hematopoietic prostaglandin D synthase (H-PGDS) (EC 5.3.99.2) (GST class-sigma) (Glutathione S-transferase) (EC 2.5.1.18) (Glutathione-dependent PGD synthase) (Glutathione-requiring prostaglandin D synthase) (Prostaglandin-H2 D-isomerase)Hpgds Gsts Pgds Ptgds2Q9JHF71
Heme oxygenase 1 (HO-1) (EC 1.14.99.3) (P32 protein)Hmox1P149011
Heme-binding protein 1 (p22HBP)Hebp1 HbpQ9R2571
HemK methyltransferase family member 2, isoform CRA_a (Protein N6amt1) (Putative N6-DNA methyltransferase A transcript variant) (Putative N6-DNA methyltransferase A2)N6amt1 Hemk2 mCG_130002Q6PRU91
Heparan sulfate 2-O-sulfotransferase 1 (2-O-sulfotransferase) (2-OST) (2OST) (EC 2.8.2.-)Hs2st1 Hs2stQ8R3H71
Hepatocyte nuclear factor 4-gamma (HNF-4-gamma) (Nuclear receptor subfamily 2 group A member 2)Hnf4g Nr2a2Q9WUU61
Hereditary hemochromatosis protein homologHfe Mr2P703871
Heterochromatin protein 1-binding protein 3Hp1bp3Q3TEA81
Heterogeneous nuclear ribonucleoprotein A0 (hnRNP A0)Hnrnpa0 Hnrpa0Q9CX861
Heterogeneous nuclear ribonucleoprotein L (hnRNP L)Hnrnpl HnrplQ8R0811
Heterogeneous nuclear ribonucleoprotein U-like protein 2 (MLF1-associated nuclear protein)Hnrnpul2 Hnrpul2 ManpQ00PI91
Heterogeneous nuclear ribonucleoproteins C1/C2 (hnRNP C1/C2)Hnrnpc HnrpcQ9Z2041
Hexosaminidase D (EC 3.2.1.52) (Beta-N-acetylhexosaminidase) (Beta-hexosaminidase D) (Hexosaminidase domain-containing protein) (N-acetyl-beta-galactosaminidase)HexdcQ3U4H61
High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A (MmPDE8) (EC 3.1.4.17)Pde8a Pde8O885021
Hippocampus abundant transcript 1 proteinHiat1P701871
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