EVpedia provide top 100+ EV markers, selected according to their identification number.
Based on EV proteomes, we defined the identification number of protein A as the number of datasets which contain protein A.
Therefore, proteins with higher identification numbers were more conserved.

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Protein name Gene symbol UniProt accession Identification number
Merlin (Moesin-ezrin-radixin-like protein) (Neurofibromin-2) (Schwannomin)Nf2 Nf-2P466621
Mesoderm development candidate 1Mesdc1Q9ERE81
Mesothelin (Pre-pro-megakaryocyte-potentiating factor) [Cleaved into: Megakaryocyte-potentiating factor (MPF); Mesothelin, cleaved form]Msln Mes MpfQ614681
Metal transporter CNNM2 (Ancient conserved domain-containing protein 2) (mACDP2) (Cyclin-M2)Cnnm2 Acdp2Q3TWN31
Metal transporter CNNM3 (Ancient conserved domain-containing protein 3) (mACDP3) (Cyclin-M3)Cnnm3 Acdp3Q32NY41
Metal transporter CNNM4 (Ancient conserved domain-containing protein 4) (mACDP4) (Cyclin-M4)Cnnm4 Acdp4 Kiaa1592Q69ZF71
Metalloendopeptidase OMA1, mitochondrial (EC 3.4.24.-) (Overlapping with the m-AAA protease 1 homolog)Oma1Q9D8H71
Metalloprotease TIKI2 (EC 3.4.-.-) (Heart, kidney and adipose-enriched transmembrane protein) (TRAB domain-containing protein 2B)Trabd2b Gm12824 Hkat Tiki2B1ATG91
Metalloproteinase inhibitor 3 (Tissue inhibitor of metalloproteinases 3) (TIMP-3)Timp3 Sun Timp-3P398761
Metalloreductase STEAP2 (EC 1.16.1.-) (Six-transmembrane epithelial antigen of prostate 2)Steap2Q8BWB61
Metastasis-associated protein MTA2 (Metastasis-associated 1-like 1)Mta2 Mta1l1Q9R1901
Methenyltetrahydrofolate synthase domain-containing proteinMthfsdQ3URQ71
Methionyl-tRNA formyltransferase, mitochondrial (MtFMT) (EC 2.1.2.9)Mtfmt FmtQ9D7991
Methyl-CpG-binding domain protein 3 (Methyl-CpG-binding protein MBD3)Mbd3Q9Z2D81
Methyl-CpG-binding domain protein 4 (EC 3.2.2.-) (Methyl-CpG-binding protein MBD4) (Mismatch-specific DNA N-glycosylase)Mbd4Q9Z2D71
Methyl-CpG-binding domain protein 5Mbd5B1AYB51
Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial (MCCase subunit alpha) (EC 6.4.1.4) (3-methylcrotonyl-CoA carboxylase 1) (3-methylcrotonyl-CoA carboxylase biotin-containing subunit) (3-methylcrotonyl-CoA:carbon dioxide ligase subunit alpha)Mccc1 MccaQ99MR81
Methylcytosine dioxygenase TET3 (EC 1.14.11.n2)Tet3Q8BG871
Methylmalonic aciduria and homocystinuria type C protein homologMmachcQ9CZD01
Methylmalonic aciduria type A homolog, mitochondrial (EC 3.6.-.-)MmaaQ8C7H11
Methyltransferase-like protein 10 (EC 2.1.1.-)Mettl10Q9D8531
Methyltransferase-like protein 23 (EC 2.1.1.-)Mettl23A2AA281
MHC class I antigen (MHC class I antigen splice variant Bl.1) (Major histocompatibility complex class I b)H2-BlO194401
Microfibril-associated glycoprotein 4Mfap4Q9D1H91
Microtubule-associated protein 1A (MAP-1A) [Cleaved into: MAP1A heavy chain; MAP1 light chain LC2]Map1a Mtap1 Mtap1aQ9QYR61
Microtubule-associated protein 1S (MAP-1S) (BPY2-interacting protein 1) (Microtubule-associated protein 8) [Cleaved into: MAP1S heavy chain; MAP1S light chain]Map1s Bpy2ip1 Map8 Mtap1sQ8C0521
Microtubule-associated protein RP/EB family member 3 (EB1 protein family member 3) (EBF3) (End-binding protein 3) (EB3) (RP3)Mapre3Q6PER31
Microtubule-associated serine/threonine-protein kinase 2 (EC 2.7.11.1)Mast2 Mast205Q605921
Microtubule-associated serine/threonine-protein kinase 3 (EC 2.7.11.1)Mast3 Kiaa0561Q3U2141
Mid1-interacting protein 1 (Gastrulation-specific G12-like protein) (Mid1-interacting G12-like protein) (Protein STRAIT11499 homolog) (Spot 14-related protein) (S14R) (Spot 14-R)Mid1ip1 Mig12Q9CQ201
MIF4G domain-containing proteinMif4gdQ3UBZ51
Migration and invasion enhancer 1Mien1 Rdx12Q9CQ861
Mimitin, mitochondrial (Myc-induced mitochondrial protein) (MMTN) (NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 2) (NDUFA12-like protein)Ndufaf2 Ndufa12lQ59J781
Mismatch repair endonuclease PMS2 (Postmeiotic segregation increased 2 (S. cerevisiae)) (Postmeiotic segregation increased 2 (S. cerevisiae), isoform CRA_d)Pms2 mCG_17957B9EJ221
Misshapen-like kinase 1 (EC 2.7.11.1) (GCK family kinase MiNK) (MAPK/ERK kinase kinase kinase 6) (MEK kinase kinase 6) (MEKKK 6) (Misshapen/NIK-related kinase) (Mitogen-activated protein kinase kinase kinase kinase 6)Mink1 Map4k6 MinkQ9JM521
Mitochondrial 2-oxoglutarate/malate carrier protein (OGCP) (Solute carrier family 25 member 11)Slc25a11Q9CR621
Mitochondrial antiviral-signaling protein (MAVS) (CARD adapter inducing interferon beta) (Cardif) (Interferon beta promoter stimulator protein 1) (IPS-1) (Virus-induced-signaling adapter) (VISA)Mavs Ips1 VisaQ8VCF01
Mitochondrial calcium uniporter regulator 1 (Coiled-coil domain-containing protein 90A, mitochondrial)Mcur1 Ccdc90aQ9CXD61
Mitochondrial chaperone BCS1 (BCS1-like protein)Bcs1lQ9CZP51
Mitochondrial dicarboxylate carrier (Solute carrier family 25 member 10)Slc25a10 DicQ9QZD81
Mitochondrial fission 1 protein (FIS1 homolog) (Tetratricopeptide repeat protein 11) (TPR repeat protein 11)Fis1 Ttc11Q9CQ921
Mitochondrial fission process protein 1 (Mitochondrial 18 kDa protein) (MTP18)Mtfp1 Mtp18Q9CRB81
Mitochondrial folate transporter/carrier (Solute carrier family 25 member 32)Slc25a32 MftcQ8BMG81
Mitochondrial import inner membrane translocase subunit TIM50Timm50 Tim50Q9D8801
Mitochondrial import inner membrane translocase subunit Tim9Timm9 Tim9 Tim9a Timm9aQ9WV981
Mitochondrial import receptor subunit TOM34 (Translocase of outer membrane 34 kDa subunit)Tomm34Q9CYG71
Mitochondrial import receptor subunit TOM40 homolog (Mitochondrial outer membrane protein of 35 kDa) (MOM35) (Protein Haymaker) (Translocase of outer membrane 40 kDa subunit homolog)Tomm40 Mom35 Tom40Q9QYA21
Mitochondrial inner membrane protease ATP23 homolog (EC 3.4.24.-) (XRCC6-binding protein 1)Xrcc6bp1Q9CWQ31
Mitochondrial inner membrane protein OXA1L (Oxidase assembly 1-like protein) (OXA1-like protein)Oxa1lQ8BGA91
Mitochondrial intermediate peptidase (MIP) (EC 3.4.24.59)MipepA6H6111
Mitochondrial intermembrane space import and assembly protein 40 (Coiled-coil-helix-coiled-coil-helix domain-containing protein 4)Chchd4 Mia40Q8VEA41
Mitochondrial ribosome-associated GTPase 1 (GTP-binding protein 7) (Mitochondrial GTPase 1)Mtg1 Gm169 Gtpbp7Q8R2R61
Mitochondrial tRNA-specific 2-thiouridylase 1 (EC 2.8.1.-)Trmu Mtu1 Trmt1Q9DAT51
Mitochondrial uncoupling protein 2 (UCP 2) (Solute carrier family 25 member 8) (UCPH)Ucp2 Slc25a8P704061
Mitofusin-2 (EC 3.6.5.-) (Hypertension-related protein 1) (Mitochondrial assembly regulatory factor) (HSG protein) (Transmembrane GTPase MFN2)Mfn2 Kiaa0214 MarfQ80U631
Mitogen activated protein kinase kinase kinase 2 (Mitogen-activated protein kinase kinase kinase 2)Map3k2 mCG_127139G5E8L81
Mitogen-activated protein kinase 6 (MAP kinase 6) (MAPK 6) (EC 2.7.11.24) (Extracellular signal-regulated kinase 3) (ERK-3)Mapk6 Erk3 Prkm4 Prkm6Q615321
Mitogen-activated protein kinase kinase kinase 4 (EC 2.7.11.25) (MAPK/ERK kinase kinase 4) (MEK kinase 4) (MEKK 4)Map3k4 Mekk4O086481
Mitogen-activated protein kinase kinase kinase 7 (EC 2.7.11.25) (Transforming growth factor-beta-activated kinase 1) (TGF-beta-activated kinase 1)Map3k7 Tak1Q620731
Mitogen-activated protein kinase kinase kinase kinase 4 (EC 2.7.11.1) (HPK/GCK-like kinase HGK) (MAPK/ERK kinase kinase kinase 4) (MEK kinase kinase 4) (MEKKK 4) (Nck-interacting kinase)Map4k4 NikP978201
Mitogen-activated protein kinase kinase kinase kinase 5 (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 5) (MEK kinase kinase 5) (MEKKK 5)Map4k5Q8BPM21
Mitogen-activated protein kinase-binding protein 1 (JNK-binding protein 1) (JNKBP-1)Mapkbp1 Jnkbp1 Kiaa0596Q6NS571
Mitotic spindle assembly checkpoint protein MAD2B (Mitotic arrest deficient 2-like protein 2) (MAD2-like protein 2)Mad2l2 Mad2b Rev7Q9D7521
MKIAA0453 protein (Fragment)Vps13d mKIAA0453Q6A0661
MKL/myocardin-like protein 1 (Basic SAP coiled-coil transcription activator) (Megakaryoblastic leukemia 1 protein homolog) (Myocardin-related transcription factor A) (MRTF-A)Mkl1 BsacQ8K4J61
MLN64 N-terminal domain homolog (STARD3 N-terminal-like protein)Stard3nl MenthoQ9DCI31
MLX-interacting protein (Transcriptional activator MondoA)Mlxip MirQ2VPU41
MOB kinase activator 1B (Mob1 homolog 1A) (Mps one binder kinase activator-like 1A)Mob1b Mobkl1aQ8BPB01
MOB kinase activator 3A (Mob1 homolog 2A) (Mps one binder kinase activator-like 2A)Mob3a Mobkl2aQ8BSU71
MOB-like protein phocein (Class II mMOB1) (Mob1 homolog 3) (Mob3) (Mps one binder kinase activator-like 3) (Preimplantation protein 3)Mob4 Mob3 Mobkl3 Phocn Prei3Q6PEB61
Mono [ADP-ribose] polymerase PARP16 (EC 2.4.2.31) (ADP-ribosyltransferase diphtheria toxin-like 15) (ARTD15) (Poly [ADP-ribose] polymerase 16) (PARP-16)Parp16Q7TMM81
Monocarboxylate transporter 7 (MCT 7) (Monocarboxylate transporter 6) (MCT 6) (Solute carrier family 16 member 6)Slc16a6 Mct7B1AT661
Monofunctional C1-tetrahydrofolate synthase, mitochondrial (EC 6.3.4.3) (Formyltetrahydrofolate synthetase)Mthfd1l Fthfsdc1Q3V3R11
MOR 3'Beta4 (Olfactory receptor 630) (Olfactory receptor MOR17-1) (Olfactory receptor Olfr630) (Protein Olfr630)Olfr630 mCG_64532Q9EQQ71
MORC family CW-type zinc finger protein 2A (Zinc finger CW-type coiled-coil domain protein 1)Morc2a Kiaa0852 Zcwcc1Q69ZX61
MORC family CW-type zinc finger protein 4 (Zinc finger CW-type coiled-coil domain protein 2)Morc4 Zcwcc2Q8BMD71
MORN repeat-containing protein 3Morn3Q8C5T41
MORN repeat-containing protein 4Morn4Q6PGF21
Mothers against decapentaplegic homolog 3 (MAD homolog 3) (Mad3) (Mothers against DPP homolog 3) (mMad3) (SMAD family member 3) (SMAD 3) (Smad3)Smad3 Madh3Q8BUN51
Mothers against decapentaplegic homolog 6 (MAD homolog 6) (Mothers against DPP homolog 6) (Mad homolog 7) (SMAD family member 6) (SMAD 6) (Smad6)Smad6 Madh6 Madh7 Msmad6O351821
Motile sperm domain-containing protein 1Mospd1Q8VEL01
mRNA cap guanine-N7 methyltransferase (EC 2.1.1.56) (RG7MT1) (mRNA (guanine-N(7)-)-methyltransferase) (mRNA cap methyltransferase)Rnmt Kiaa0398Q9D0L81
mRNA-capping enzyme (HCE) (MCE1) [Includes: Polynucleotide 5'-triphosphatase (TPase) (mRNA 5'-triphosphatase) (EC 3.1.3.33); mRNA guanylyltransferase (EC 2.7.7.50) (GTP--RNA guanylyltransferase) (GTase)]Rngtt Cap1aO552361
Multicilin (Multiciliate differentiation and DNA synthesis-associated cell cycle protein) (Protein Idas)Mcidas Gm6320 Idas Mci McinQ3UZ451
Multidrug resistance-associated protein 6 (ATP-binding cassette sub-family C member 6)Abcc6 Mrp6Q9R1S71
Multiple epidermal growth factor-like domains protein 9 (Multiple EGF-like domains protein 9) (Epidermal growth factor-like protein 5) (EGF-like protein 5)Megf9 Egfl5 Kiaa0818Q8BH271
Multiple myeloma tumor-associated protein 2 homologMmtag2Q99LX51
Multivesicular body subunit 12A (ESCRT-I complex subunit MVB12A) (Protein FAM125A)Mvb12a Fam125aQ78HU31
Muscarinic acetylcholine receptor M5Chrm5Q920H41
Myb-related transcription factor, partner of profilin (Myb-related protein p42POP) (Partner of profilin)Mypop P42popQ8R4U11
Myb/SANT-like DNA-binding domain-containing protein 1Msantd1Q8BIL21
Myb/SANT-like DNA-binding domain-containing protein 2Msantd2Q6NZR21
Mycophenolic acid acyl-glucuronide esterase, mitochondrial (EC 3.1.1.93) (Alpha/beta hydrolase domain-containing protein 10) (Abhydrolase domain-containing protein 10)Abhd10Q6PE151
Myelin expression factor 2 (MEF-2) (MyEF-2)Myef2 Kiaa1341 Mef2Q8C8541
Myelin regulatory factor-like proteinMyrfl Gm239Q3UN701
Myelin transcription factor 1 (MyT1) (Neural zinc finger factor 2) (NZF-2)Myt1 Kiaa0835 Nzf2Q8CFC21
Myelin transcription factor 1-like proteinMyt1lD3Z1P71
Myeloid cell surface antigen CD33 (Sialic acid-binding Ig-like lectin 3) (Siglec-3) (CD antigen CD33)Cd33 Siglec3Q639941
Myeloma-overexpressed gene 2 protein homologMyeov2Q3U8981
Myocyte enhancer factor 2B, isoform CRA_a (Myocyte-specific enhancer factor 2B) (Protein 2310045N01Rik)2310045N01Rik Mef2b mCG_23096K7N7F11
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