EVpedia provide top 100+ EV markers, selected according to their identification number.
Based on EV proteomes, we defined the identification number of protein A as the number of datasets which contain protein A.
Therefore, proteins with higher identification numbers were more conserved.

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Protein name Gene symbol UniProt accession Identification number
Plastin-2 (65 kDa macrophage protein) (L-plastin) (Lymphocyte cytosolic protein 1) (LCP-1) (pp65)Lcp1 Pls2Q612331
Plastin-3 (T-plastin)Pls3Q99K511
Platelet glycoprotein V (Fragment)Gp5Q9QZU31
Platelet receptor Gi240Q9D6591
Platelet-derived growth factor C (PDGF-C) (Fallotein) (Spinal cord-derived growth factor) (SCDGF) (VEGF-E) [Cleaved into: Platelet-derived growth factor C, latent form (PDGFC latent form); Platelet-derived growth factor C, receptor-binding form (PDGFC receptor-binding form)]Pdgfc ScdgfQ8CI191
Platelet-derived growth factor subunit BSisF8VQM51
PleckstrinPlekQ9JHK51
Pleckstrin homology domain-containing family A member 1 (PH domain-containing family A member 1) (Tandem PH domain-containing protein 1) (TAPP-1)Plekha1 Tapp1Q8BUL61
Pleckstrin homology domain-containing family A member 6 (PH domain-containing family A member 6) (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3)Plekha6 Pepp3Q7TQG11
Pleckstrin homology domain-containing family F member 1 (PH domain-containing family F member 1) (Lysosome-associated apoptosis-inducing protein containing PH and FYVE domains)Plekhf1 LapfQ3TB821
Pleckstrin homology domain-containing family G member 2 (PH domain-containing family G member 2) (Common site lymphoma/leukemia guanine nucleotide exchange factor) (Common site lymphoma/leukemia GEF)Plekhg2Q6KAU71
Pleckstrin homology domain-containing family G member 3 (PH domain-containing family G member 3)Plekhg3 Kiaa0599Q4VAC91
Pleckstrin homology-like domain family A member 1 (Proline- and glutamine-rich protein) (PQ-rich protein) (PQR protein) (T-cell death-associated gene 51 protein)Phlda1 Tdag51Q623921
Pleckstrin homology-like domain family A member 3 (TDAG51/Ipl homolog 1)Phlda3 Tih1Q9WV951
Pleiotrophin (PTN) (Heparin-binding brain mitogen) (HBBM) (Heparin-binding growth factor 8) (HBGF-8) (Heparin-binding growth-associated molecule) (HB-GAM) (Heparin-binding neutrophic factor) (HBNF) (Osteoblast-specific factor 1) (OSF-1)PtnP630891
Plexin domain-containing protein 1 (Tumor endothelial marker 7)Plxdc1 Tem7Q91ZV71
Plexin-A1 (Plex 1) (Plexin-1)Plxna1 Kiaa4053P702061
PNMA-like protein 1Pnmal1Q80VM81
Pogo transposable element with ZNF domainPogz Kiaa0461Q8BZH41
Poliovirus receptor-related protein 3 (Nectin-3) (CD antigen CD113)Pvrl3Q9JLB91
Polo-like kinase 3 (Drosophila) (Polo-like kinase 3 (Drosophila), isoform CRA_c) (Serine/threonine-protein kinase PLK3)Plk3 mCG_14437Q6P5711
Poly (ADP-ribose) glycohydrolase, isoform CRA_c (Poly(ADP-ribose) glycohydrolase)Parg mCG_117129G3X8U81
Poly A binding protein, cytoplasmic 2 (Poly(A) binding protein, cytoplasmic 2) (PolyA binding protein, testis-enriched isoform) (Protein Pabpc2)Pabpc2 mCG_13635Q620291
Poly [ADP-ribose] polymerase 12 (PARP-12) (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 12) (ARTD12) (Zinc finger CCCH domain-containing protein 1)Parp12 Zc3hdc1Q8BZ201
Poly [ADP-ribose] polymerase 9 (PARP-9) (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 9) (ARTD9) (B aggressive lymphoma protein homolog)Parp9 BalQ8CAS91
Poly(A) polymerase alpha (PAP-alpha) (EC 2.7.7.19) (Polynucleotide adenylyltransferase)Papola Pap PlapQ611831
Poly(A) RNA polymerase, mitochondrial (PAP) (EC 2.7.7.19) (PAP-associated domain-containing protein 1) (Polynucleotide adenylyltransferase)Mtpap Papd1Q9D0D31
Poly(A)-specific ribonuclease PARN (EC 3.1.13.4) (Polyadenylate-specific ribonuclease)ParnQ8VDG31
Poly(ADP-ribose) glycohydrolase ARH3 (EC 3.2.1.143) (ADP-ribosylhydrolase 3) ([Protein ADP-ribosylarginine] hydrolase-like protein 2)Adprhl2 Arh3Q8CG721
Polycomb complex protein BMI-1 (Polycomb group RING finger protein 4)Bmi1 Bmi-1 Pcgf4P259161
Polycomb group RING finger protein 6 (Mel18 and Bmi1-like RING finger) (RING finger protein 134)Pcgf6 Mblr Rnf134Q99NA91
Polycystin-2 (Polycystic kidney disease 2 protein homolog)Pkd2O352451
Polyhomeotic-like protein 1 (mPH1) (Early development regulatory protein 1) (RAE-28)Phc1 Edr Edr1 Rae28Q640281
Polyhomeotic-like protein 2 (mPH2) (Early development regulatory protein 2) (p36)Phc2 Edr2 Ph2Q9QWH11
Polymerase delta-interacting protein 3 (S6K1 Aly/REF-like target) (SKAR)Poldip3Q8BG811
Polypeptide N-acetylgalactosaminyltransferase 1 (EC 2.4.1.41) (Polypeptide GalNAc transferase 1) (GalNAc-T1) (pp-GaNTase 1) (Protein-UDP acetylgalactosaminyltransferase 1) (UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 1) [Cleaved into: Polypeptide N-acetylgalactosaminyltransferase 1 soluble form]Galnt1O089121
Polypeptide N-acetylgalactosaminyltransferase 11 (EC 2.4.1.41) (Polypeptide GalNAc transferase 11) (GalNAc-T11) (pp-GaNTase 11) (Protein-UDP acetylgalactosaminyltransferase 11) (UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 11)Galnt11Q921L81
Polyribonucleotide nucleotidyltransferase 1, mitochondrial (EC 2.7.7.8) (3'-5' RNA exonuclease OLD35) (PNPase old-35) (Polynucleotide phosphorylase 1) (PNPase 1) (Polynucleotide phosphorylase-like protein)Pnpt1 PnpaseQ8K1R31
Polyubiquitin-B [Cleaved into: Ubiquitin]UbbP0CG491
Post-GPI attachment to proteins factor 3 (PER1-like domain-containing protein 1)Pgap3 Perld1A2A5591
Postacrosomal sheath WW domain-binding protein (WW domain-binding protein 2-like)Wbp2nl PawpQ9D5291
Potassium channel subfamily K member 9 (Acid-sensitive potassium channel protein TASK-3) (TWIK-related acid-sensitive K(+) channel 3)Kcnk9 Task3Q3LS211
Potassium channel tetramerisation domain containing 12b (Potassium channel tetramerisation domain containing 12b, isoform CRA_a) (Protein Kctd12b)Kctd12b mCG_61677Q8C7J61
Potassium channel tetramerisation domain containing 18, isoform CRA_a (Protein Kctd18)Kctd18 mCG_117471E0CZ261
Potassium channel, subfamily K, member 15 (Protein Kcnk15)Kcnk15B2RVL11
Potassium voltage-gated channel subfamily A member 4 (Voltage-gated potassium channel subunit Kv1.4)Kcna4Q614231
Potassium voltage-gated channel subfamily D member 2 (Voltage-gated potassium channel subunit Kv4.2)Kcnd2 Kiaa1044 MNCb-7013Q9Z0V21
Potassium voltage-gated channel subfamily D member 3 (Voltage-gated potassium channel subunit Kv4.3)Kcnd3Q9Z0V11
Potassium voltage-gated channel subfamily E member 1-like protein (MinK-like protein)Kcne1lQ9QZ261
Potassium voltage-gated channel subfamily G member 4 (Voltage-gated potassium channel subunit Kv6.4)Kcng4Q80XM31
Ppfia1 protein (Protein Ppfia1)Ppfia1B2RXQ21
PQ-loop repeat-containing protein 3Pqlc3Q8C6U21
Pre-mRNA 3'-end-processing factor FIP1 (FIP1-like 1 protein)Fip1l1Q9D8241
Pre-mRNA-processing factor 39Prpf39E9QJV41
Pre-mRNA-processing factor 40 homolog A (Formin-binding protein 11) (FBP-11) (Formin-binding protein 3)Prpf40a Fbp11 Fnbp3Q9R1C71
Pre-mRNA-processing factor 6 (PRP6 homolog) (U5 snRNP-associated 102 kDa protein) (U5-102 kDa protein)Prpf6Q91YR71
Pre-mRNA-splicing factor 38APrpf38aQ4FK661
Pre-mRNA-splicing factor CWC25 homolog (Coiled-coil domain-containing protein 49) (Spliceosome-associated protein homolog CWC25)Cwc25 Ccdc49Q9DBF71
Pre-mRNA-splicing factor ISY1 homologIsy1 Kiaa1160Q69ZQ21
Pre-mRNA-splicing factor SYF1 (XPA-binding protein 2)Xab2 Syf1Q9DCD21
Pre-mRNA-splicing factor SYF2 (CCNDBP1-interactor) (mp29) (p29)Syf2 Cbpin GcipipQ9D1981
Predicted gene, EG235327 (Protein Gm4894)Gm4894 EG235327Q8CA091
Predicted gene, EG328231 (Protein Gm5082)Gm5082 EG328231B2RV891
Predicted gene, EG384813 (Protein Gm5346) (Testase-6)Gm5346 Adam36 EG384813Q7M7661
Predicted gene, EG434881 (Protein Samt2)Samt2 EG434881 Gm5647Q497M01
Prefoldin subunit 6 (Protein Ke2)Pfdn6 H2-Ke2 Pfd6Q039581
Pregnancy-specific glycoprotein 22 (Protein Psg22)Psg22 BC050099Q810J11
PRELI domain-containing protein 2Prelid2Q0VBB01
Presenilins-associated rhomboid-like protein, mitochondrial (EC 3.4.21.105) (Mitochondrial intramembrane-cleaving protease PARL) [Cleaved into: P-beta (Pbeta)]Parl PsarlQ5XJY41
Prickle-like protein 1Prickle1Q3U5C71
Prion-like protein doppel (Doppelganger) (PrPLP)PrndQ9QUG31
PRKCA-binding proteinPick1E9PUZ51
Pro-neuregulin-4, membrane-bound isoform (Pro-NRG4) [Cleaved into: Neuregulin-4 (NRG-4)]Nrg4Q9WTX41
Probable arginine--tRNA ligase, mitochondrial (EC 6.1.1.19) (Arginyl-tRNA synthetase) (ArgRS)Rars2 RarslQ3U1861
Probable ATP-dependent RNA helicase DDX10 (EC 3.6.4.13) (DEAD box protein 10)Ddx10Q80Y441
Probable ATP-dependent RNA helicase DDX17 (EC 3.6.4.13) (DEAD box protein 17)Ddx17Q501J61
Probable ATP-dependent RNA helicase DDX27 (EC 3.6.4.13) (DEAD box protein 27)Ddx27Q921N61
Probable ATP-dependent RNA helicase DDX41 (EC 3.6.4.13) (DEAD box protein 41)Ddx41Q91VN61
Probable ATP-dependent RNA helicase DDX49 (EC 3.6.4.13) (DEAD box protein 49)Ddx49Q4FZF31
Probable ATP-dependent RNA helicase DDX58 (EC 3.6.4.13) (DEAD box protein 58) (RIG-I-like receptor 1) (RLR-1) (Retinoic acid-inducible gene 1 protein) (RIG-1) (Retinoic acid-inducible gene I protein) (RIG-I)Ddx58Q6Q8991
Probable ATP-dependent RNA helicase DDX59 (EC 3.6.4.13) (DEAD box protein 59)Ddx59Q9DBN91
Probable ATP-dependent RNA helicase DHX40 (EC 3.6.4.13) (DEAH box protein 40)Dhx40Q6PE541
Probable cation-transporting ATPase 13A1 (CATP) (EC 3.6.3.-)Atp13a1 Atp13aQ9EPE91
Probable cysteine--tRNA ligase, mitochondrial (EC 6.1.1.16) (Cysteinyl-tRNA synthetase) (CysRS)Cars2Q8BYM81
Probable E3 ubiquitin-protein ligase RNF144A (EC 6.3.2.-) (RING finger protein 144A) (UbcM4-interacting protein 4) (Ubiquitin-conjugating enzyme 7-interacting protein 4)Rnf144a Kiaa0161 Rnf144 Ubce7ip4 Uip4Q925F31
Probable ergosterol biosynthetic protein 28ORF11Q9ERY91
Probable G-protein coupled receptor 114Gpr114 Gm1109Q3V3Z31
Probable G-protein coupled receptor 133 (G-protein coupled receptor PGR25)Gpr133 Pgr25Q80T321
Probable G-protein coupled receptor 33Gpr33O884161
Probable G-protein coupled receptor 75Gpr75Q6X6321
Probable global transcription activator SNF2L2 (EC 3.6.4.-) (ATP-dependent helicase SMARCA2) (BRG1-associated factor 190B) (BAF190B) (Protein brahma homolog) (SNF2-alpha) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2)Smarca2 Baf190b Brm Snf2a Snf2l2Q6DIC01
Probable JmjC domain-containing histone demethylation protein 2C (EC 1.14.11.-) (Jumonji domain-containing protein 1C)Jmjd1c Jhdm2c Kiaa1380Q69ZK61
Probable low affinity copper uptake protein 2 (Copper transporter 2) (CTR2) (Solute carrier family 31 member 2)Slc31a2Q9CPU91
Probable lysosomal cobalamin transporter (LMBR1 domain-containing protein 1) (Protein N90b)Lmbrd1Q8K0B21
Probable N-acetyltransferase CML1 (EC 2.3.1.-) (Camello-like protein 1)Cml1Q9JIZ01
Probable palmitoyltransferase ZDHHC20 (EC 2.3.1.225) (Zinc finger DHHC domain-containing protein 20) (DHHC-20)Zdhhc20Q5Y5T11
Probable palmitoyltransferase ZDHHC21 (EC 2.3.1.225) (GABA-A receptor-associated membrane protein 3) (Zinc finger DHHC domain-containing protein 21) (DHHC-21)Zdhhc21 Gramp3Q9D2701
Probable peptide chain release factor C12orf65 homolog, mitochondrial0Q80VP51
Probable peptidyl-tRNA hydrolase (PTH) (EC 3.1.1.29)Ptrh1Q8BW001
Probable phospholipid-transporting ATPase 11C (EC 3.6.3.1) (ATPase class VI type 11C)Atp11cQ9QZW01
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