EVpedia provide top 100+ EV markers, selected according to their identification number.
Based on EV proteomes, we defined the identification number of protein A as the number of datasets which contain protein A.
Therefore, proteins with higher identification numbers were more conserved.

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Protein name Gene symbol UniProt accession Identification number
Sterol O-acyltransferase 1 (EC 2.3.1.26) (Acyl-coenzyme A:cholesterol acyltransferase 1) (ACAT-1) (Cholesterol acyltransferase 1)Soat1 AcactQ612631
Steryl-sulfatase (EC 3.1.6.2) (Arylsulfatase C) (ASC) (Steroid sulfatase) (Steryl-sulfate sulfohydrolase)StsP504271
Stimulator of interferon genes protein (mSTING) (Endoplasmic reticulum interferon stimulator) (ERIS) (Mediator of IRF3 activation) (MMITA) (Transmembrane protein 173)Tmem173 Eris Mita Mpys StingQ3TBT31
Stress-induced-phosphoprotein 1 (STI1) (mSTI1) (Hsc70/Hsp90-organizing protein) (Hop)Stip1Q608641
Striated muscle-specific serine/threonine-protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1)Speg Apeg1 Kiaa1297Q624071
Striatin-interacting proteins 2 (Protein FAM40B)Strip2 Fam40b Kiaa1170 StripbQ8C9H61
Structural maintenance of chromosomes flexible hinge domain-containing protein 1Smchd1 Kiaa0650Q6P5D81
Structural maintenance of chromosomes protein 3 (SMC protein 3) (SMC-3) (Basement membrane-associated chondroitin proteoglycan) (Bamacan) (Chondroitin sulfate proteoglycan 6) (Chromosome segregation protein SmcD) (Mad member-interacting protein 1)Smc3 Bam Bmh Cspg6 Mmip1 Smc3l1 SmcdQ9CW031
Structure-specific endonuclease subunit SLX4 (BTB/POZ domain-containing protein 12)Slx4 Btbd12Q6P1D71
Submandibular gland protein CMuc19 SmgcQ6JHY21
Submaxillary gland androgen-regulated protein 2, isoform gamma (Salivary protein MSG2, isoform gamma)Smr2 Msg2 Vcs2O359851
Succinate dehydrogenase assembly factor 1, mitochondrial (SDH assembly factor 1) (LYR motif-containing protein 8)Sdhaf1Q3U2761
Succinyl-CoA ligase [ADP-forming] subunit beta, mitochondrial (EC 6.2.1.5) (ATP-specific succinyl-CoA synthetase subunit beta) (Succinyl-CoA synthetase beta-A chain) (SCS-betaA)Sucla2Q9Z2I91
Sulfatase-modifying factor 1 (EC 1.8.99.-) (C-alpha-formylglycine-generating enzyme 1)Sumf1 FgeQ8R0F31
Sulfate transporter (Diastrophic dysplasia protein homolog) (ST-OB) (Solute carrier family 26 member 2)Slc26a2 Dtd DtdstQ622731
Sulfotransferase 6B1 (ST6B1) (Thyroxine sulfotransferase) (EC 2.8.2.n2)Sult6b1P0CC031
SUMO-specific isopeptidase USPL1 (EC 3.4.22.-) (Ubiquitin-specific peptidase-like protein 1)Uspl1Q3ULM61
SUN domain-containing protein 1 (Protein unc-84 homolog A) (Sad1/unc-84 protein-like 1)Sun1 Unc84aQ9D6661
Superkiller viralicidic activity 2-like 2 (EC 3.6.4.13) (ATP-dependent helicase SKIV2L2)Skiv2l2Q9CZU31
Superoxide dismutase [Mn], mitochondrial (EC 1.15.1.1)Sod2 Sod-2P096711
Suppression of tumorigenicity 5 protein (DENN domain-containing protein 2B)St5 Dennd2bQ924W71
Suppressor of cytokine signaling 1 (SOCS-1) (JAK-binding protein) (JAB) (STAT-induced STAT inhibitor 1) (SSI-1)Socs1 Cish1 Ssi1O357161
Suppressor of cytokine signaling 2 (SOCS-2) (Cytokine-inducible SH2 protein 2) (CIS-2)Socs2 Cis2 Cish2O357171
Suppressor of fused homologSufuQ9Z0P71
Suppressor of G2 allele of SKP1 homologSugt1Q9CX341
Suppressor of tumorigenicity 7 protein (mRay)St7Q99M961
Suppressor of tumorigenicity 7 protein-like (ST7-related protein)St7l St7rQ8K4P71
SURP and G-patch domain-containing protein 2 (Arginine/serine-rich-splicing factor 14) (Splicing factor, arginine/serine-rich 14)Sugp2 Sfrs14 Srsf14Q8CH091
Sushi repeat-containing protein SRPX2Srpx2Q8R0541
Sushi, nidogen and EGF-like domain-containing protein 1 (Secreted protein SST-3) (Stromal nidogen extracellular matrix protein)Sned1 SnepQ70E201
SWI/SNF complex subunit SMARCC2 (BRG1-associated factor 170) (BAF170) (SWI/SNF complex 170 kDa subunit) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 2)Smarcc2 Baf170Q6PDG51
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1 (EC 3.6.4.12) (ATP-dependent helicase SMARCAD1) (Enhancer trap locus homolog 1) (Etl-1)Smarcad1 Etl1 Kiaa1122Q046921
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 3 (60 kDa BRG-1/Brm-associated factor subunit C) (BRG1-associated factor 60C) (BAF60C) (mBAF60c)Smarcd3 Baf60cQ6P9Z11
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1-related (SMARCE1-related protein) (BRCA2-associated factor 35) (HMG box-containing protein 20B) (Structural DNA-binding protein BRAF35)Hmg20b Braf35 Hmgx2 Smarce1rQ9Z1041
SymplekinSympkF8WJD41
Synapsin-1 (Synapsin I)Syn1 Syn-1O889351
Synaptogyrin-1Syngr1O551001
Synaptogyrin-2 (Cellugyrin)Syngr2O551011
Synaptojanin-1Synj1D3Z6561
Synaptotagmin-11 (Synaptotagmin XI) (SytXI)Syt11Q9R0N31
Synaptotagmin-4 (Synaptotagmin IV) (SytIV)Syt4 Syt3P407491
Synaptotagmin-like protein 4 (Exophilin-2) (Granuphilin)Sytl4 Slp4Q9R0Q11
Synemin (Desmuslin)Synm Dmn Kiaa0353Q70IV51
Syntaxin 2 (Syntaxin-2)Stx2 EpimQ80W451
Syntaxin-12Stx12Q9ER001
Syntaxin-16Stx16Q8BVI51
Syntaxin-3Stx3 Stx3aQ647041
Syntaxin-6Stx6Q9JKK11
Syntaxin-binding protein 1 (Protein unc-18 homolog 1) (Unc18-1) (Protein unc-18 homolog A) (Unc-18A)Stxbp1O085991
Syntaxin-binding protein 4 (Syntaxin 4-interacting protein) (STX4-interacting protein) (Synip)Stxbp4Q9WV891
Syntaxin-binding protein 5-like (Lethal(2) giant larvae protein homolog 4) (Tomosyn-2)Stxbp5l Llgl4Q5DQR41
Syntenin-1 (Scaffold protein Pbp1) (Syndecan-binding protein 1)SdcbpO089921
Syntenin-2 (Syndecan-binding protein 2)Sdcbp2Q99JZ01
T-box brain protein 1 (T-brain-1) (TBR-1) (TES-56)Tbr1Q643361
T-cell ecto-ADP-ribosyltransferase 1 (EC 2.4.2.31) (ADP-ribosyltransferase 2a pseudogene) (ADP-ribosyltransferase C2 and C3 toxin-like 2) (ARTC2) (Mono(ADP-ribosyl)transferase 2A) (T-cell NAD(P)(+)--arginine ADP-ribosyltransferase 1) (T-cell differentiation marker Rt6 homolog 1) (T-cell mono(ADP-ribosyl)transferase 1)Art2a Art2a-ps Rt6-1 Rt6.1P179811
T-cell leukemia translocation-altered gene protein homologTctaQ8VEA71
T-cell surface glycoprotein CD8 beta chain (Lymphocyte antigen 3) (T-cell membrane glycoprotein Ly-3) (T-cell surface glycoprotein Lyt-3) (CD antigen CD8b)Cd8b Cd8b1 Ly-3 Lyt-3 Lyt3P103001
T-cell surface protein tactile (Cell surface antigen CD96) (T cell-activated increased late expression protein) (CD antigen CD96)Cd96Q3U0X81
T-complex protein 1 subunit alpha (TCP-1-alpha) (CCT-alpha) (Tailless complex polypeptide 1A) (TCP-1-A) (Tailless complex polypeptide 1B) (TCP-1-B)Tcp1 Cct1 CctaP119831
T-complex protein 11-like protein 2Tcp11l2Q8K1H71
T-lymphocyte activation antigen CD80 (Activation B7-1 antigen) (B7) (CD antigen CD80)Cd80 B7Q006091
T-lymphoma invasion and metastasis-inducing protein 2 (TIAM-2) (SIF and TIAM1-like exchange factor)Tiam2 Kiaa2016 StefQ6ZPF31
TAF5-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 5L (PCAF-associated factor 65 beta) (PAF65-beta)Taf5l Paf65bQ91WQ51
Tail-anchored protein insertion receptor WRB (Tryptophan-rich basic protein) (WRB)WrbQ8K0D71
Target of EGR1 protein 1Toe1Q9D2E21
Tartrate-resistant acid phosphatase type 5 (TR-AP) (EC 3.1.3.2) (Tartrate-resistant acid ATPase) (TrATPase) (Type 5 acid phosphatase)Acp5 T5ap TrapQ051171
Taste receptor type 2Vmn1r100 Vmn1r148Q9EPS51
TATA box-binding protein-like protein 1 (TBP-like protein 1) (21 kDa TBP-like protein) (TATA box-binding protein-related factor 2) (TBP-related factor 2) (TBP-like factor) (TBP-related protein)Tbpl1 Tlf Tlp Tlp21 Trf2 TrpP623401
TBC1 domain family member 10A (EBP50-PDX interactor of 64 kDa) (EPI64 protein)Tbc1d10a Epi64 Tbc1d10P588021
TBC1 domain family member 17Tbc1d17Q8BYH71
TBC1 domain family member 24Tbc1d24 Kiaa1171Q3UUG61
TBC1 domain family member 2ATbc1d2 Tbc1d2aB1AVH71
TBCC domain-containing protein 1Tbccd1Q640P71
Tectonic-2Tctn2 Tect2Q2MV571
Tectonin beta-propeller repeat-containing protein 1Tecpr1 Kiaa1358Q80VP01
Telomere-associated protein RIF1 (Rap1-interacting factor 1 homolog) (mRif1)Rif1Q6PR541
Tensin-3 (Tensin-like SH2 domain-containing protein 1)Tns3 Tens1Q5SSZ51
TERF1-interacting nuclear factor 2 (Terf1 (TRF1)-interacting nuclear factor 2) (Terf1 (TRF1)-interacting nuclear factor 2, isoform CRA_b)Tinf2 mCG_22054Q8K1K31
Terminal uridylyltransferase 4 (TUTase 4) (EC 2.7.7.52) (Zinc finger CCHC domain-containing protein 11)Zcchc11 Kiaa0191 Tut4B2RX141
Testican-2 (SPARC/osteonectin, CWCV, and Kazal-like domains proteoglycan 2)Spock2 Ticn2Q9ER581
Testican-3 (SPARC/osteonectin, CWCV, and Kazal-like domains proteoglycan 3)Spock3Q8BKV01
Testin-2 [Cleaved into: Testin-1]0Q80UB01
Testis-expressed sequence 10 proteinTex10Q3URQ01
Testis-expressed sequence 33 proteinTex33 Ean57Q9D9J21
Tetraspanin-12 (Tspan-12) (Transmembrane 4 superfamily member 12)Tspan12 Tm4sf12Q8BKT61
Tetraspanin-14 (Tspan-14) (Transmembrane 4 superfamily member 14)Tspan14 D14Ertd226e Tm4sf14Q8QZY61
Tetraspanin-5 (Tspan-5) (Tetraspan NET-4) (Transmembrane 4 superfamily member 9)Tspan5 Tm4sf9P620801
Tetratricopeptide repeat protein 1 (TPR repeat protein 1)Ttc1Q91Z381
Tetratricopeptide repeat protein 23 (TPR repeat protein 23)Ttc23Q8CHY71
Tetratricopeptide repeat protein 32 (TPR repeat protein 32)Ttc32Q9DAC71
Tetratricopeptide repeat protein 34 (TPR repeat protein 34)Ttc34Q8C0Q31
Tetratricopeptide repeat protein 39C (TPR repeat protein 39C)Ttc39cQ8VE091
Tetratricopeptide repeat protein 5 (TPR repeat protein 5) (Stress-responsive activator of p300)Ttc5 StrapQ99LG41
Tetratricopeptide repeat protein 7A (TPR repeat protein 7A)Ttc7a Ttc7Q8BGB21
Tetratricopeptide repeat protein 9C (TPR repeat protein 9C)Ttc9cQ810A31
Tex21 proteinTex21Q497Q31
TGF-beta-activated kinase 1 and MAP3K7-binding protein 3 (Mitogen-activated protein kinase kinase kinase 7-interacting protein 3) (TAK1-binding protein 3) (TAB-3) (TGF-beta-activated kinase 1-binding protein 3)Tab3 Kiaa4135 Map3k7ip3Q571K41
THAP domain-containing protein 11 (Ronin)Thap11 MNCb-2032Q9JJD01
THAP domain-containing protein 2Thap2Q9D3051
THAP domain-containing protein 3Thap3Q8BJ251
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