EVpedia provide top 100+ EV markers, selected according to their identification number.
Based on EV proteomes, we defined the identification number of protein A as the number of datasets which contain protein A.
Therefore, proteins with higher identification numbers were more conserved.

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Protein name Gene symbol UniProt accession Identification number
KH domain-containing, RNA-binding, signal transduction-associated protein 3 (RNA-binding protein T-Star) (Sam68-like mammalian protein 2) (SLM-2) (Sam68-like phosphotyrosine protein)KHDRBS3 SALP SLM2O755254
KIAA1033 proteinKIAA1033B7ZKT94
Kinesin-like proteinKIF5B hCG_37538D3DRX64
Kinesin-like protein (Fragment)KIF5BQ6P1644
Kinesin-like protein KIF21BKIF21B KIAA0449O750374
KRT8 protein (Fragment)KRT8Q969I04
L-plastin variant (Fragment)0Q53FI14
La-related protein 6 (Acheron) (Achn) (La ribonucleoprotein domain family member 6)LARP6Q9BRS84
Lactadherin (Fragment)MFGE8H0YKS84
Lactoperoxidase (LPO) (EC 1.11.1.7) (Salivary peroxidase) (SPO)LPO SAPXP220794
Lactosylceramide 4-alpha-galactosyltransferase (EC 2.4.1.228) (Alpha-1,4-N-acetylglucosaminyltransferase) (Alpha-1,4-galactosyltransferase) (Alpha4Gal-T1) (CD77 synthase) (Globotriaosylceramide synthase) (Gb3 synthase) (P1/Pk synthase) (UDP-galactose:beta-D-galactosyl-beta1-R 4-alpha-D-galactosyltransferase)A4GALT A14GALT A4GALT1Q9NPC44
Laminin alpha 5 chain (Fragment)0O750794
Laminin alpha-3 chain variant 1LAMA3B0YJ324
Laminin subunit alpha-5 (Laminin-10 subunit alpha) (Laminin-11 subunit alpha) (Laminin-15 subunit alpha)LAMA5 KIAA0533 KIAA1907Q5U4N94
LAMP1 protein variant (Fragment)0Q59FZ04
Large neutral amino acids transporter 1 (Fragment)SLC7A5Q2MCL64
Lebercilin-like protein (Leber congenital amaurosis 5-like protein)LCA5L C21orf13O954474
Leucine zipper putative tumor suppressor 3 (ProSAP-interacting protein 1) (ProSAPiP1)LZTS3 KIAA0552 PROSAPIP1O602994
Leucine-rich melanocyte differentiation-associated proteinLRMDA C10orf11 CDA017Q9H2I84
Leucine-rich repeat and guanylate kinase domain-containing proteinLRGUKQ96M694
Leucine-rich repeat-containing protein 20LRRC20 UNQ2429/PRO4989Q8TCA04
Leucine-rich repeat-containing protein 25 (Monocyte and plasmacytoid-activated protein)LRRC25 MAPA UNQ6169/PRO20174Q8N3864
Leucine-rich repeat-containing protein 26 (BK channel auxiliary gamma subunit LRRC26) (Cytokeratin-associated protein in cancer)LRRC26 CAPCQ2I0M44
Leucine-rich repeat-containing protein 32 (Garpin) (Glycoprotein A repetitions predominant) (GARP)LRRC32 D11S833E GARPQ143924
Leucine-rich repeat-containing protein 37A3LRRC37A3 KIAA0563O603094
Leucine-rich repeat-containing protein 75A (Leucine-rich repeat-containing protein FAM211A)LRRC75A C17orf76 FAM211AQ8NAA54
Leukocyte immunoglobulin-like receptor subfamily B member 2 (LIR-2) (Leukocyte immunoglobulin-like receptor 2) (CD85 antigen-like family member D) (Immunoglobulin-like transcript 4) (ILT-4) (Monocyte/macrophage immunoglobulin-like receptor 10) (MIR-10) (CD antigen CD85d)LILRB2 ILT4 LIR2 MIR10Q8N4234
Leukocyte receptor cluster member 8LENG8 KIAA1932Q96PV64
Leukocyte-associated immunoglobulin-like receptor 2 (LAIR-2) (CD antigen CD306)LAIR2 CD306Q6ISS44
Leukosialin (Galactoglycoprotein) (GALGP) (Leukocyte sialoglycoprotein) (Sialophorin) (CD antigen CD43)SPN CD43A8K9B14
LIM and calponin homology domains-containing protein 1 (Fragment)LIMCH1H0Y8P34
LIM domain and actin-binding protein 1LIMA1F8VQE14
Limbin (Ellis-van Creveld syndrome protein 2) (EVC2)EVC2 LBNQ86UK54
Lipoprotein, Lp(A)LPAQ1HP674
LON peptidase N-terminal domain and RING finger protein 1 (RING finger protein 191)LONRF1 RNF191Q17RB84
Lon protease homolog, mitochondrial (EC 3.4.21.-) (Lon protease-like protein) (LONP) (Mitochondrial ATP-dependent protease Lon) (Serine protease 15)LONP1B3KU284
Low-density lipoprotein receptor (Fragment)LDLRJ3KMZ94
Low-density lipoprotein receptor-related protein 12 (LRP-12) (Suppressor of tumorigenicity 7 protein)LRP12 ST7Q9Y5614
LRP protein (Fragment)LRPQ6LAF44
LRRN4 C-terminal-like proteinLRRN4CL UNQ728/PRO1410Q8ND944
Lymphocyte antigen 6 complex locus protein G6fLY6G6F C6orf21 G6F LY6G6D NG32Q5SQ644
Lysine-specific demethylase 6B (EC 1.14.11.-) (JmjC domain-containing protein 3) (Jumonji domain-containing protein 3) (Lysine demethylase 6B)KDM6B JMJD3 KIAA0346O150544
Lysophosphatidic acid receptor 3 (LPA receptor 3) (LPA-3) (Lysophosphatidic acid receptor Edg-7)LPAR3 EDG7 LPA3Q9UBY54
Lysosome membrane protein 2SCARB2D6RDG04
M6PR proteinM6PRQ6I9U34
Macrophage colony-stimulating factor 1 receptor (CSF-1 receptor) (CSF-1-R) (CSF-1R) (M-CSF-R) (EC 2.7.10.1) (Proto-oncogene c-Fms) (CD antigen CD115)CSF1R FMSP073334
Major prion protein (Fragment)PRNPD4P3Q74
MAP7 domain-containing protein 2MAP7D2Q96T174
MARVEL domain-containing protein 1MARVELD1 MRVLDC1Q9BSK04
Matrilin-4MATN4O954604
Matrin-3MATR3D6REM64
Matrix metalloproteinase-25 (MMP-25) (EC 3.4.24.-) (Leukolysin) (Membrane-type matrix metalloproteinase 6) (MT-MMP 6) (MTMMP6) (Membrane-type-6 matrix metalloproteinase) (MT6-MMP) (MT6MMP)MMP25 MMP20 MMPL1 MT6MMPQ9NPA24
Mediator of RNA polymerase II transcription subunit 15 (Activator-recruited cofactor 105 kDa component) (ARC105) (CTG repeat protein 7a) (Mediator complex subunit 15) (Positive cofactor 2 glutamine/Q-rich-associated protein) (PC2 glutamine/Q-rich-associated protein) (TPA-inducible gene 1 protein) (TIG-1) (Trinucleotide repeat-containing gene 7 protein)MED15 ARC105 CTG7A PCQAP TIG1 TNRC7Q96RN54
Mediator of RNA polymerase II transcription subunit 16 (Mediator complex subunit 16) (Thyroid hormone receptor-associated protein 5) (Thyroid hormone receptor-associated protein complex 95 kDa component) (Trap95) (Vitamin D3 receptor-interacting protein complex 92 kDa component) (DRIP92)MED16 DRIP92 THRAP5Q9Y2X04
Mediator of RNA polymerase II transcription subunit 17 (Activator-recruited cofactor 77 kDa component) (ARC77) (Cofactor required for Sp1 transcriptional activation subunit 6) (CRSP complex subunit 6) (Mediator complex subunit 17) (Thyroid hormone receptor-associated protein complex 80 kDa component) (Trap80) (Transcriptional coactivator CRSP77) (Vitamin D3 receptor-interacting protein complex 80 kDa component) (DRIP80)MED17 ARC77 CRSP6 DRIP77 DRIP80 TRAP80Q9NVC64
Mediator of RNA polymerase II transcription subunit 6 (Activator-recruited cofactor 33 kDa component) (ARC33) (Mediator complex subunit 6) (hMed6) (Renal carcinoma antigen NY-REN-28)MED6 ARC33O755864
Melanoma-associated antigen C1 (Cancer/testis antigen 7.1) (CT7.1) (MAGE-C1 antigen)MAGEC1O607324
Melanoma-associated antigen D2MAGED2Q5H9094
Membrane cofactor protein (Fragment)CD46R4GN184
Membrane-associated transporter protein (Melanoma antigen AIM1) (Protein AIM-1) (Solute carrier family 45 member 2)SLC45A2 AIM1 MATPQ9UMX94
Membrane-spanning 4-domains subfamily A member 10 (CD20 antigen-like 7)MS4A10 CD20L7 MS4A9Q96PG24
MeninMEN1 SCG2O002554
Metalloendopeptidase (EC 3.4.24.-) (Fragment)0Q59F714
Metaxin-2 (Fragment)MTX2C9JAZ14
Methylmalonic aciduria type A protein, mitochondrial (EC 3.6.-.-)MMAAQ8IVH44
Methyltransferase-like protein 16 (EC 2.1.1.-) (Methyltransferase 10 domain-containing protein)METTL16 METT10DQ86W504
Methyltransferase-like protein 7B (EC 2.1.1.-)METTL7B UNQ594/PRO1180Q6UX534
MHC class I antigenHLA-BC0KXH24
MHC class I antigen (Fragment)HLA-AD9UAY24
Microtubule-associated protein 1AMAP1AE9PGC84
Microtubule-associated serine/threonine-protein kinase 2 (EC 2.7.11.1)MAST2 KIAA0807 MAST205Q6P0Q84
MIF4G domain-containing protein (SLBP-interacting protein 1) (hSLIP1)MIF4GD SLIP1A9UHW64
Mirror-image polydactyly gene 1 proteinMIPOL1Q8TD104
MIT domain-containing protein 1 (Fragment)MITD1B8ZZL54
Mitochondrial chaperone BCS1 (h-BCS1) (BCS1-like protein)BCS1L BCS1Q9Y2764
Mitochondrial heat shock 60kD protein 1 variant 1HSPD1B3GQS74
Mitochondrial import inner membrane translocase subunit Tim10TIMM10 TIM10P620724
Mitochondrial ornithine transporter 1 (Solute carrier family 25 member 15)SLC25A15 ORNT1 SP1855Q9Y6194
Mitochondrial Rho GTPase 1 (MIRO-1) (hMiro-1) (EC 3.6.5.-) (Rac-GTP-binding protein-like protein) (Ras homolog gene family member T1)RHOT1 ARHT1Q8IXI24
Mitogen-activated protein kinase (EC 2.7.11.24)MAPK1Q499G74
Mitogen-activated protein kinase 7 (MAP kinase 7) (MAPK 7) (EC 2.7.11.24) (Big MAP kinase 1) (BMK-1) (Extracellular signal-regulated kinase 5) (ERK-5)MAPK7 BMK1 ERK5 PRKM7Q131644
Mitogen-activated protein kinase kinase kinase kinase 2 (EC 2.7.11.1) (B lymphocyte serine/threonine-protein kinase) (Germinal center kinase) (GC kinase) (MAPK/ERK kinase kinase kinase 2) (MEK kinase kinase 2) (MEKKK 2) (Rab8-interacting protein)MAP4K2 GCK RAB8IPQ128514
Mitogen-activated protein kinase kinase kinase kinase 4MAP4K4E7EN194
Mitogen-activated protein kinase-binding protein 1 (JNK-binding protein 1) (JNKBP-1)MAPKBP1 JNKBP1 KIAA0596O603364
Mitotic checkpoint serine/threonine-protein kinase BUB1 beta (EC 2.7.11.1) (MAD3/BUB1-related protein kinase) (hBUBR1) (Mitotic checkpoint kinase MAD3L) (Protein SSK1)BUB1B BUBR1 MAD3L SSK1O605664
Mitotic-spindle organizing protein 2A (Mitotic-spindle organizing protein associated with a ring of gamma-tubulin 2A)MZT2A FAM128A MOZART2AQ6P5824
MLN64 N-terminal domain homolog (Fragment)STARD3NLC9JPX54
Molybdenum cofactor sulfurase (MCS) (MOS) (MoCo sulfurase) (hMCS) (EC 2.8.1.9) (Molybdenum cofactor sulfurtransferase)MOCOSQ96EN84
MORC family CW-type zinc finger protein 3 (Nuclear matrix protein 2) (Zinc finger CW-type coiled-coil domain protein 3)MORC3 KIAA0136 NXP2 ZCWCC3Q141494
MORF4 family-associated protein 1 (Protein PGR1) (Protein associated with MRG of 14 kDa)MRFAP1 PAM14 PGR1Q9Y6054
Motile sperm domain-containing protein 2MOSPD2Q8NHP64
Mucin-1 (MUC-1) (Breast carcinoma-associated antigen DF3) (Cancer antigen 15-3) (CA 15-3) (Carcinoma-associated mucin) (Episialin) (H23AG) (Krebs von den Lungen-6) (KL-6) (PEMT) (Peanut-reactive urinary mucin) (PUM) (Polymorphic epithelial mucin) (PEM) (Tumor-associated epithelial membrane antigen) (EMA) (Tumor-associated mucin) (CD antigen CD227) [Cleaved into: Mucin-1 subunit alpha (MUC1-NT) (MUC1-alpha); Mucin-1 subunit beta (MUC1-beta) (MUC1-CT)]MUC1 PUMQ7Z5504
Mucin-15 (MUC-15)MUC15 UNQ750/PRO1481Q8N3874
Mucin-19 (MUC-19)MUC19Q7Z5P94
Mucosal addressin cell adhesion molecule 1 (MAdCAM-1) (hMAdCAM-1)MADCAM1Q134774
Muscarinic acetylcholine receptor M2CHRM2P081724
MuskelinMKLN1Q9UL634
Myb-related protein A (A-Myb) (Myb-like protein 1)MYBL1 AMYBP102434
MYCBP-associated protein (AMAM-1) (AMY-1-binding protein 1) (AMAP-1)MYCBPAP AMAP1Q8TBZ24
Myelin protein P0 (Myelin peripheral protein) (MPP) (Myelin protein zero)MPZP251894
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