EVpedia provide top 100+ EV markers, selected according to their identification number.
Based on EV proteomes, we defined the identification number of protein A as the number of datasets which contain protein A.
Therefore, proteins with higher identification numbers were more conserved.

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Protein name Gene symbol UniProt accession Identification number
Potassium voltage-gated channel subfamily H member 8 (ELK1) (hElk1) (Ether-a-go-go-like potassium channel 3) (ELK channel 3) (ELK3) (Voltage-gated potassium channel subunit Kv12.1)KCNH8Q96L424
PRA1 family protein0B3KQB44
PRA1 family protein (Fragment)RABAC1M0QXH14
Pre-mRNA cleavage complex 2 protein Pcf11 (Pre-mRNA cleavage complex II protein Pcf11)PCF11 KIAA0824O949134
Pre-mRNA-splicing factor 18 (PRP18 homolog) (hPRP18)PRPF18 HPRP18Q996334
Pre-mRNA-splicing factor SLU7 (hSlu7)SLU7O953914
Pregnancy-specific beta-1-glycoprotein 9 (PS-beta-G-9) (PSBG-9) (Pregnancy-specific glycoprotein 9) (PS34) (Pregnancy-specific beta-1 glycoprotein B) (PS-beta-B) (Pregnancy-specific beta-1-glycoprotein 11) (PS-beta-G-11) (PSBG-11) (Pregnancy-specific glycoprotein 11) (Pregnancy-specific glycoprotein 7) (PSG7)PSG9 PSG11Q008874
Presenilin (EC 3.4.23.-) (Fragment)0Q53FV84
Probable ATP-dependent RNA helicase DDX17 (EC 3.6.4.13) (DEAD box protein 17) (DEAD box protein p72) (DEAD box protein p82) (RNA-dependent helicase p72)DDX17H3BLZ84
Probable ATP-dependent RNA helicase DDX52 (EC 3.6.4.13) (ATP-dependent RNA helicase ROK1-like) (DEAD box protein 52)DDX52 ROK1 HUSSY-19Q9Y2R44
Probable ATP-dependent RNA helicase DHX34 (EC 3.6.4.13) (DEAH box protein 34)DHX34 DDX34 KIAA0134Q141474
Probable ATP-dependent RNA helicase DHX37 (EC 3.6.4.13) (DEAH box protein 37)DHX37 DDX37 KIAA1517Q8IY374
Probable E3 ubiquitin-protein ligase DTX2 (EC 2.3.2.27) (Protein deltex-2) (Deltex2) (hDTX2) (RING finger protein 58) (RING-type E3 ubiquitin transferase DTX2)DTX2 KIAA1528 RNF58Q86UW94
Probable G-protein coupled receptor 179 (Probable G-protein coupled receptor 158-like 1) (GPR158-like)GPR179 GPR158L GPR158L1Q6PRD14
Probable ribosome biogenesis protein RLP24 (Ribosomal L24 domain-containing protein 1) (Ribosomal protein L24-like)RSL24D1 C15orf15 RPL24L My024Q9UHA34
Probable tRNA pseudouridine synthase 1 (EC 5.4.99.-)TRUB1 PUS4Q8WWH54
Procollagen-lysine,2-oxoglutarate 5-dioxygenase 3 (Fragment)PLOD3H7C2V14
Profilin (Fragment)PFN2 hCG_21343D3DNI34
Programmed cell death protein 4 (Neoplastic transformation inhibitor protein) (Nuclear antigen H731-like) (Protein 197/15a)PDCD4 H731B5ME914
Proline-rich protein PRCC (Papillary renal cell carcinoma translocation-associated gene protein)PRCC TPRCQ927334
Prolyl 3-hydroxylase 2 (EC 1.14.11.7) (Leprecan-like protein 1) (Myxoid liposarcoma-associated protein 4)P3H2 LEPREL1 MLAT4Q8IVL54
Prosaposin receptor GPR37 (Endothelin B receptor-like protein 1) (ETBR-LP-1) (G-protein coupled receptor 37) (Parkin-associated endothelin receptor-like receptor) (PAELR)GPR37O153544
Prostate-associated microseminoprotein (PC3-secreted microprotein)MSMP PSMPQ1L6U94
Proteasome endopeptidase complex (EC 3.4.25.1)PSMA2C9JCK54
Proteasome inhibitor PI31 subunit (Fragment)PSMF1Q5QPM94
Proteasome subunit alpha type (EC 3.4.25.1)0B4E0X64
Proteasome subunit alpha type (EC 3.4.25.1) (Fragment)0Q53GF54
Proteasome subunit alpha type (EC 3.4.25.1) (Fragment)PSMA4H0YL694
Proteasome subunit alpha type-4PSMA4H0YMV34
Proteasome subunit beta type (EC 3.4.25.1)PSMB10Q6IB224
Proteasome subunit beta type-5 (Fragment)PSMB5H0YJM84
Protein ABHD14B (cDNA FLJ52723, highly similar to Abhydrolase domain-containing protein 14B)ABHD14BB4DQI44
Protein AF1qMLLT11 AF1QQ130154
Protein arginine N-methyltransferase 5 (EC 2.1.1.-)0B4DV004
Protein argonaute-3 (Argonaute3) (hAgo3) (Argonaute RISC catalytic component 3) (Eukaryotic translation initiation factor 2C 3) (eIF-2C 3) (eIF2C 3)AGO3 EIF2C3Q9H9G74
Protein ARPC4-TTLL3ARPC4-TTLL3A0A0A6YYG94
Protein BHLHb9 (bHLHb9) (Transcription regulator of 60 kDa) (p60TRP)BHLHB9 KIAA1701Q6PI774
Protein CASC3 (Cancer susceptibility candidate gene 3 protein) (Metastatic lymph node gene 51 protein) (MLN 51) (Protein barentsz) (Btz)CASC3 MLN51O152344
Protein CLEC16A (C-type lectin domain family 16 member A)CLEC16A KIAA0350Q2KHT34
Protein ECT2 (Epithelial cell-transforming sequence 2 oncogene)ECT2Q9H8V34
Protein eyes shut homolog (Epidermal growth factor-like protein 10) (EGF-like protein 10) (Epidermal growth factor-like protein 11) (EGF-like protein 11) (Protein spacemaker homolog)EYS C6orf178 C6orf179 C6orf180 EGFL10 EGFL11 SPAM UNQ9424/PRO34591Q5T1H14
Protein FAM111AFAM111A KIAA1895Q96PZ24
Protein FAM111B (Cancer-associated nucleoprotein)FAM111B CANPQ6SJ934
Protein FAM160A1FAM160A1Q05DH44
Protein FAM200AFAM200A C7orf38Q8TCP94
Protein FAM3B (Cytokine-like protein 2-21) (Pancreatic-derived factor) (PANDER)FAM3B C21orf11 C21orf76 PRED44 UNQ320/PRO365P584994
Protein FAM65BFAM65B C6orf32 DIFF48 KIAA0386 PL48Q9Y4F94
Protein kinase C (EC 2.7.11.13) (Fragment)PRKCIB5BUK74
Protein kinase C and casein kinase substrate in neurons protein 3 (Fragment)PACSIN3A0A0C4DGG14
Protein kinase C theta type (EC 2.7.11.13) (nPKC-theta)PRKCQ PRKCTQ047594
Protein MRVI1 (Inositol 1,4,5-trisphosphate receptor-associated cGMP kinase substrate) (JAW1-related protein MRVI1)MRVI1 IRAG JAW1LQ9Y6F64
Protein odr-4 homolog (hODR-4) (LAG1-interacting protein) (Transactivated by transforming growth factor beta protein 1)ODR4 C1orf27 TTG1 TTG1AQ5SWX84
Protein patched homolog 1 (PTC) (PTC1)PTCH1 PTCHQ136354
Protein phosphatase 1 regulatory subunit 11 (Hemochromatosis candidate gene V protein) (HCG V) (Protein phosphatase inhibitor 3)PPP1R11 HCGV TCTE5O609274
Protein phosphatase 1 regulatory subunit 12B (Myosin phosphatase-targeting subunit 2) (Myosin phosphatase target subunit 2)PPP1R12B MYPT2O602374
Protein phosphatase 1 regulatory subunit 14A (17 kDa PKC-potentiated inhibitory protein of PP1) (Protein kinase C-potentiated inhibitor protein of 17 kDa) (CPI-17)PPP1R14A CPI17 PPP1INLQ96A004
Protein phosphatase 1 regulatory subunit 37 (Leucine-rich repeat-containing protein 68)PPP1R37 KIAA1986 LRRC68O758644
Protein phosphatase Slingshot homolog 2 (EC 3.1.3.16) (EC 3.1.3.48) (SSH-like protein 2) (SSH-2L) (hSSH-2L)SSH2 KIAA1725 SSH2LQ76I764
Protein PRRC2B (HLA-B-associated transcript 2-like 1) (Proline-rich coiled-coil protein 2B)PRRC2B BAT2L BAT2L1 KIAA0515Q5JSZ54
Protein RTF2 homolog (Replication termination factor 2 domain-containing protein 1)RTFDC1 C20orf43 AD-007 CDA05 HSPC164 HSPC169Q9BY424
Protein S (Alpha), isoform CRA_b (Vitamin K-dependent protein S)PROS1 hCG_1790803G5E9F84
Protein S100 (S100 calcium-binding protein)0B2R5774
Protein SCAF8 (CDC5L complex-associated protein 7) (RNA-binding motif protein 16) (SR-related and CTD-associated factor 8)SCAF8 CCAP7 KIAA1116 RBM16Q9UPN64
Protein SETSIP (SET pseudogene protein 18) (SET similar protein) (Similar to SET translocation protein)SETSIP SETP18P0DME04
Protein sprouty homolog 1 (Spry-1)SPRY1O436094
Protein SZT2 (Seizure threshold 2 protein homolog)SZT2 C1orf84 KIAA0467Q5T0114
Protein unc-119 homolog A (Retinal protein 4) (hRG4)UNC119 RG4Q134324
Protein unc-13 homolog A (Munc13-1)UNC13A KIAA1032Q9UPW84
Protein unc-13 homolog C (Munc13-3)UNC13CQ8NB664
Protein unc-45 homolog B (Unc-45B) (SMUNC45)UNC45B CMYA4 UNC45Q8IWX74
Protein-glutamine gamma-glutamyltransferase 2 (Fragment)TGM2A2A2994
Protein-tyrosine sulfotransferase 1 (EC 2.8.2.20) (Tyrosylprotein sulfotransferase 1) (TPST-1)TPST1O605074
Proteinase-activated receptor 2 (PAR-2) (Coagulation factor II receptor-like 1) (G-protein coupled receptor 11) (Thrombin receptor-like 1) [Cleaved into: Proteinase-activated receptor 2, alternate cleaved 1; Proteinase-activated receptor 2, alternate cleaved 2]F2RL1 GPR11 PAR2P550854
Prothymosin alphaPTMAB8ZZQ64
Protocadherin alpha-3 (PCDH-alpha-3)PCDHA3Q9Y5H84
Protocadherin alpha-6 (PCDH-alpha-6)PCDHA6 CNRS2Q9UN734
Protocadherin beta-5 (PCDH-beta-5)PCDHB5Q9Y5E44
Protocadherin beta-8 (PCDH-beta-8) (Protocadherin-3I)PCDHB8 PCDH3IQ9UN664
Protocadherin gamma-B7 (PCDH-gamma-B7)PCDHGB7Q9Y5F84
Protocadherin-17 (Protocadherin-68)PCDH17 PCDH68 PCH68O149174
Protocadherin-23 (Cadherin-27) (Cadherin-like protein CDHJ) (Cadherin-like protein VR8) (Protein dachsous homolog 2) (Protocadherin PCDHJ)DCHS2 CDH27 CDHJ PCDH23 PCDHJQ6V1P94
Protogenin (Protein Shen-Dan)PRTGQ2VWP74
Proton myo-inositol cotransporter (H(+)-myo-inositol cotransporter) (Hmit) (H(+)-myo-inositol symporter) (Solute carrier family 2 member 13)SLC2A13Q96QE24
PRSS1 proteinPRSS1Q3SY194
Purine nucleoside phosphorylase (EC 2.4.2.1) (Inosine-guanosine phosphorylase)0Q8N7G14
Putative ATP-dependent RNA helicase DHX33 (EC 3.6.4.13) (DEAH box protein 33)DHX33 DDX33Q9H6R04
Putative gamma-glutamyltransferase light chain 3GGTLC3B5MD394
Putative high mobility group protein B1-like 1 (High mobility group protein B1 pseudogene 1) (Putative high mobility group protein 1-like 1) (HMG-1L1)HMGB1P1 HMG1L1 HMGB1L1B2RPK04
Putative N-acetylated-alpha-linked acidic dipeptidase (NAALADase) (EC 3.4.-.-) (Cell growth-inhibiting gene 26 protein) (Prostate-specific membrane antigen-like protein) (Putative folate hydrolase 1B)FOLH1B PSMAL GIG26Q9HBA94
Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX32 (EC 3.6.4.13) (DEAD/H box 32) (DEAD/H helicase-like protein 1) (DHLP1) (DEAH box protein 32) (HuDDX32)DHX32 DDX32Q7L7V14
Putative protein arginine N-methyltransferase 9 (Putative protein arginine N-methyltransferase 10) (EC 2.1.1.-)PRMT9 PRMT10Q6P2P24
Putative protein FAM45BFAM45BP FAM45 HT011Q6NSW54
Putative transferase CAF17, mitochondrial (EC 2.1.-.-) (Iron-sulfur cluster assembly factor homolog)IBA57 C1orf69Q5T4404
Putative tRNA (cytidine(32)/guanosine(34)-2'-O)-methyltransferase (EC 2.1.1.205) (2'-O-ribose RNA methyltransferase TRM7 homolog) (Protein ftsJ homolog 1)FTSJ1 JM23Q9UET64
Putative tRNA pseudouridine synthase Pus10 (EC 5.4.99.25) (Coiled-coil domain-containing protein 139) (tRNA pseudouridine 55 synthase) (Psi55 synthase) (tRNA pseudouridylate synthase) (tRNA-uridine isomerase)PUS10 CCDC139 DOBIQ3MIT24
Putative uncharacterized protein CUL3 (Fragment)CUL3Q53S544
Putative uncharacterized protein DKFZp434N1827 (Fragment)DKFZp434N1827Q9UFA54
Putative uncharacterized protein DKFZp666B131 (Fragment)DKFZp666B131Q658Z14
Putative uncharacterized protein DKFZp686B04128DKFZp686B04128Q68D084
Putative uncharacterized protein DKFZp686C02218 (Fragment)DKFZp686C02218Q7Z3744
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