EVpedia provide top 100+ EV markers, selected according to their identification number.
Based on EV proteomes, we defined the identification number of protein A as the number of datasets which contain protein A.
Therefore, proteins with higher identification numbers were more conserved.

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Protein name Gene symbol UniProt accession Identification number
Tyrosine-protein kinase SgK223 (EC 2.7.10.2) (Sugen kinase 223)SGK223Q86YV54
Tyrosine-protein kinase STYK1 (EC 2.7.10.2) (Novel oncogene with kinase domain) (Protein PK-unique) (Serine/threonine/tyrosine kinase 1)STYK1 NOKQ6J9G04
Tyrosine-protein kinase Tec (EC 2.7.10.2)TEC PSCTK4P426804
Tyrosine-protein phosphatase non-receptor type 3 (EC 3.1.3.48) (Protein-tyrosine phosphatase H1) (PTP-H1)PTPN3 PTPH1P260454
U4/U6 small nuclear ribonucleoprotein Prp31 (Fragment)PRPF31E7EN724
U5 snRNP-specific protein variant (Fragment)0Q53GM64
Ubiquitin carboxyl-terminal hydrolase 1 (EC 3.4.19.12) (Deubiquitinating enzyme 1) (hUBP) (Ubiquitin thioesterase 1) (Ubiquitin-specific-processing protease 1)USP1O947824
Ubiquitin carboxyl-terminal hydrolase 31 (EC 3.4.19.12) (Deubiquitinating enzyme 31) (Ubiquitin thioesterase 31) (Ubiquitin-specific-processing protease 31)USP31 KIAA1203Q70CQ44
Ubiquitin thioesterase (EC 3.4.19.12)OTUB1F5H6Q14
Ubiquitin thioesterase (EC 3.4.19.12)0B4DPD54
Ubiquitin-conjugating enzyme E2 A (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme A) (RAD6 homolog A) (HR6A) (hHR6A) (Ubiquitin carrier protein A) (Ubiquitin-protein ligase A)UBE2A RAD6AP494594
Ubiquitin-conjugating enzyme E2 E1 (EC 2.3.2.23) ((E3-independent) E2 ubiquitin-conjugating enzyme E1) (EC 2.3.2.24) (E2 ubiquitin-conjugating enzyme E1) (UbcH6) (Ubiquitin carrier protein E1) (Ubiquitin-protein ligase E1)UBE2E1 UBCH6P519654
Ubiquitin-conjugating enzyme E2 E2 (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme E2) (UbcH8) (Ubiquitin carrier protein E2) (Ubiquitin-protein ligase E2)UBE2E2 UBCH8Q96LR54
Ubiquitin-conjugating enzyme E2 R1 (EC 2.3.2.23) ((E3-independent) E2 ubiquitin-conjugating enzyme R1) (EC 2.3.2.24) (E2 ubiquitin-conjugating enzyme R1) (Ubiquitin-conjugating enzyme E2-32 kDa complementing) (Ubiquitin-conjugating enzyme E2-CDC34) (Ubiquitin-protein ligase R1)CDC34 UBCH3 UBE2R1P494274
UBX domain-containing protein 6 (Fragment)UBXN6K7EP324
UDP-Gal:betaGlcNAc beta 1,4-galactosyltransferase, polypeptide 4 (UDP-Gal:betaGlcNAc beta 1,4-galactosyltransferase, polypeptide 4, isoform CRA_a) (cDNA, FLJ95212, Homo sapiens UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase,polypeptide 4 (B4GALT4), mRNA)B4GALT4 hCG_22565B2RAZ54
UMP-CMP kinaseCMPK1Q5T0D24
Uncharacterized aarF domain-containing protein kinase 1 (EC 2.7.11.-)ADCK1Q86TW24
Uncharacterized protein0Q144734
Uncharacterized proteinDKFZp686K03196Q6N0954
Uncharacterized protein0Q6P5S34
Uncharacterized protein0G3V5994
Uncharacterized protein0K7ERI84
Uncharacterized protein0E7ETN34
Uncharacterized protein (Fragment)0Q9UMH54
Uncharacterized protein (Fragment)0E5RI564
Uncharacterized protein (Fragment)0K7EIP64
Uncharacterized protein C17orf47C17orf47Q8NEP44
Uncharacterized protein C9orf152C9orf152Q5JTZ54
Uncharacterized protein CXorf38CXorf38Q8TB034
Uncharacterized protein KIAA0408KIAA0408Q6ZU524
Uncharacterized protein KIAA1211KIAA1211Q6ZU354
Uncharacterized protein KIAA1614KIAA1614Q5VZ464
Unconventional myosin-VIMYO6A0A0A0MRM84
Unconventional myosin-VIMYO6E7EW204
UPF0449 protein C19orf25C19orf25Q9UFG54
Upstream-binding protein 1 (Transcription factor LBP-1)UBP1 LBP1Q9NZI74
UQCRH protein (Ubiquinol-cytochrome c reductase hinge protein, isoform CRA_c)UQCRH hCG_22091Q567R04
Uridine monophosphate synthetase isoform IUMPSB5LY714
Uroplakin 2 (Fragment)0Q9UEE84
USP9X protein (Fragment)USP9XQ6P4684
UTP--glucose-1-phosphate uridylyltransferaseUGP2A0A087WYS14
V-type proton ATPase subunit aATP6V0A1B7Z6414
V-type proton ATPase subunit d 1 (Fragment)ATP6V0D1J3QL144
V5-4 protein (Fragment)V5-4Q5NV794
Vacuolar fusion protein MON1 homolog B (HSV-1 stimulation-related gene 1 protein) (HSV-I stimulating-related protein)MON1B HSRG1 KIAA0872 SAND2Q7L1V24
Vacuolar protein sorting 35 variant (Fragment)0Q53FR44
Vacuolar protein sorting-associated protein 13B (Cohen syndrome protein 1)VPS13B CHS1 COH1 KIAA0532Q7Z7G84
Vacuolar protein sorting-associated protein 13DVPS13D KIAA0453Q5THJ44
Vacuolar protein sorting-associated protein 37B (Fragment)VPS37BF5H4M04
Valine--tRNA ligase, mitochondrial (EC 6.1.1.9) (Valyl-tRNA synthetase) (ValRS) (Valyl-tRNA synthetase-like)VARS2 KIAA1885 VARS2L VARSLQ5ST304
Ventral anterior homeobox 1VAX1Q5SQQ94
Ventricular zone-expressed PH domain-containing protein homolog 1 (Protein melted)VEPH1 KIAA1692 VEPHQ14D044
Very long-chain acyl-CoA synthetase (VLACS) (VLCS) (EC 6.2.1.-) (Fatty acid transport protein 2) (FATP-2) (Fatty-acid-coenzyme A ligase, very long-chain 1) (Long-chain-fatty-acid--CoA ligase) (EC 6.2.1.3) (Solute carrier family 27 member 2) (THCA-CoA ligase) (Very long-chain-fatty-acid-CoA ligase)SLC27A2 ACSVL1 FACVL1 FATP2 VLACSO149754
Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase (EC 4.2.1.134)HACD3H3BPZ14
Vesicle-associated membrane protein 1 (VAMP-1) (Synaptobrevin-1)VAMP1 SYB1P237634
Vesicle-trafficking protein SEC22a (SEC22 vesicle-trafficking protein homolog A) (SEC22 vesicle-trafficking protein-like 2)SEC22A SEC22L2Q96IW74
Vesicular integral-membrane protein VIP36LMAN2D6RBV24
Volume-regulated anion channel subunit LRRC8B (Leucine-rich repeat-containing protein 8B) (T-cell activation leucine repeat-rich protein) (TA-LRRP)LRRC8B KIAA0231 UNQ6413/PRO21207Q6P9F74
von Willebrand factor A domain-containing protein 7 (Protein G7c)VWA7 C6orf27 G7C NG37Q9Y3344
WAP four-disulfide core domain protein 1 (Prostate stromal protein ps20) (ps20 growth inhibitor)WFDC1 PS20Q9HC574
WD repeat domain 1, isoform CRA_a (WD repeat-containing protein 1 isoform 1 variant) (Fragment)WDR1 hCG_19377Q53GN44
WD repeat domain phosphoinositide-interacting protein 3 (WIPI-3) (WD repeat-containing protein 45-like) (WDR45-like protein) (WD repeat-containing protein 45B) (WIPI49-like protein)WDR45B WDR45L WIPI3Q5MNZ64
WD repeat-containing protein 47 (Neuronal enriched MAP-interacting protein) (Nemitin)WDR47 KIAA0893O949674
WD repeat-containing protein 55WDR55Q9H6Y24
WD repeat-containing protein 62WDR62 C19orf14O433794
WD repeat-containing protein 70WDR70Q9NW824
WD repeat-containing protein 72WDR72Q3MJ134
WW domain-containing adapter protein with coiled-coilWAC KIAA1844Q9BTA94
Xylosyltransferase 1 (EC 2.4.2.26) (Peptide O-xylosyltransferase 1) (Xylosyltransferase I) (XT-I) (XylT-I)XYLT1 XT1Q86Y384
Y+L amino acid transporter 1 (Monocyte amino acid permease 2) (MOP-2) (Solute carrier family 7 member 7) (y(+)L-type amino acid transporter 1) (Y+LAT1) (y+LAT-1)SLC7A7Q9UM014
Zinc finger and BTB domain-containing protein 10 (Zinc finger protein RIN ZF)ZBTB10 RINZF RINZFCQ96DT74
Zinc finger and BTB domain-containing protein 26 (Zinc finger protein 481) (Zinc finger protein Bioref)ZBTB26 KIAA1572 ZNF481Q9HCK04
Zinc finger and BTB domain-containing protein 41ZBTB41 FRBZ1Q5SVQ84
Zinc finger C2HC domain-containing protein 1AZC2HC1A C8orf70 FAM164A CGI-62Q96GY04
Zinc finger CCCH-type antiviral protein 1ZC3HAV1C9J6P44
Zinc finger FYVE domain-containing protein 21 (ZF21)ZFYVE21Q9BQ244
Zinc finger matrin-type protein 2ZMAT2Q96NC04
Zinc finger MYM-type protein 4 (Zinc finger protein 262)ZMYM4 KIAA0425 ZNF262Q5VZL54
Zinc finger protein 230 (Zinc finger protein FDZF2)ZNF230 FDZF2Q9UIE04
Zinc finger protein 24 (Retinoic acid suppression protein A) (RSG-A) (Zinc finger and SCAN domain-containing protein 3) (Zinc finger protein 191) (Zinc finger protein KOX17)ZNF24 KOX17 ZNF191 ZSCAN3P170284
Zinc finger protein 268 (Zinc finger protein HZF3)ZNF268Q145874
Zinc finger protein 292ZNF292 KIAA0530O602814
Zinc finger protein 419ZNF419 ZNF419AQ96HQ04
Zinc finger protein 510ZNF510 KIAA0972Q9Y2H84
Zinc finger protein 559ZNF559Q9BR844
Zinc finger protein 607ZNF607Q96SK34
Zinc transporter 7 (Fragment)SLC30A7H0Y3624
Zinc transporter 9 (ZnT-9) (Human embryonic lung protein) (HuEL) (Solute carrier family 30 member 9)SLC30A9 C4orf1 HUELQ6PML94
Zinc transporter ZIP2 (6A1) (Eti-1) (Solute carrier family 39 member 2) (Zrt- and Irt-like protein 2) (ZIP-2) (hZIP2)SLC39A2 ZIP2Q9NP944
Zinc transporter ZIP4SLC39A4A6NDY54
Zinc transporter ZIP8 (BCG-induced integral membrane protein in monocyte clone 103 protein) (LIV-1 subfamily of ZIP zinc transporter 6) (LZT-Hs6) (Solute carrier family 39 member 8) (Zrt- and Irt-like protein 8) (ZIP-8)SLC39A8 BIGM103 ZIP8 PP3105Q9C0K14
1-acyl-sn-glycerol-3-phosphate acyltransferase beta (EC 2.3.1.51) (1-acylglycerol-3-phosphate O-acyltransferase 2) (1-AGP acyltransferase 2) (1-AGPAT 2) (Lysophosphatidic acid acyltransferase beta) (LPAAT-beta)AGPAT2O151203
1-acyl-sn-glycerol-3-phosphate acyltransferase epsilon (EC 2.3.1.51) (1-acylglycerol-3-phosphate O-acyltransferase 5) (1-AGP acyltransferase 5) (1-AGPAT 5) (Lysophosphatidic acid acyltransferase epsilon) (LPAAT-epsilon)AGPAT5Q9NUQ23
10 kDa heat shock protein, mitochondrial (Heat shock 10kDa protein 1 (Chaperonin 10), isoform CRA_b)HSPE1 hCG_21429B8ZZL83
14-3-3 protein epsilon (cDNA FLJ51975, moderately similar to 14-3-3 protein epsilon (14-3-3E))YWHAEB4DJF23
14-3-3 protein theta (Fragment)YWHAQE9PG153
2-(3-amino-3-carboxypropyl)histidine synthase subunit 1 (EC 2.5.1.108) (Diphthamide biosynthesis protein 1) (Diphtheria toxin resistance protein 1) (Ovarian cancer-associated gene 1 protein) (S-adenosyl-L-methionine:L-histidine 3-amino-3-carboxypropyltransferase 1)DPH1 DPH2L DPH2L1 OVCA1Q9BZG83
2-hydroxyacyl-CoA lyase 1 (EC 4.1.-.-) (2-hydroxyphytanoyl-CoA lyase) (2-HPCL) (Phytanoyl-CoA 2-hydroxylase 2)HACL1 HPCL HPCL2 PHYH2 HSPC279Q9UJ833
26S protease regulatory subunit 4 (P26s4) (26S proteasome AAA-ATPase subunit RPT2) (Proteasome 26S subunit ATPase 1)PSMC1B4DR633
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