EVpedia provide top 100+ EV markers, selected according to their identification number.
Based on EV proteomes, we defined the identification number of protein A as the number of datasets which contain protein A.
Therefore, proteins with higher identification numbers were more conserved.

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Protein name Gene symbol UniProt accession Identification number
Beta-caseinCSN2 CASBP058143
Beta-crystallin B1 (Beta-B1 crystallin)CRYBB1P536743
Beta-crystallin B2 (Beta-B2 crystallin) (Beta-crystallin Bp)CRYBB2 CRYB2 CRYB2AP433203
Beta-defensin 1 (BD-1) (hBD-1) (Defensin, beta 1)DEFB1 BD1 HBD1P600223
Beta-defensin 129 (Beta-defensin 29) (DEFB-29) (Defensin, beta 129)DEFB129 C20orf87 DEFB29 UNQ5794/PRO19599Q9H1M33
Beta-glucuronidaseGUSBF8WBK63
Beta-hexosaminidase subunit betaHEXBD6REQ83
Beta-hexosaminidase subunit beta (Fragment)HEXBH0Y9B63
Beta-ureidopropionase (EC 3.5.1.6) (BUP-1) (Beta-alanine synthase) (N-carbamoyl-beta-alanine amidohydrolase)UPB1 BUP1Q9UBR13
Bifunctional purine biosynthesis protein PURH (Fragment)ATICH7C1S23
Bone morphogenetic protein 8B (BMP-8) (BMP-8B) (Osteogenic protein 2) (OP-2)BMP8B BMP8P348203
BRCA1-associated protein (EC 2.3.2.27) (BRAP2) (Impedes mitogenic signal propagation) (IMP) (RING finger protein 52) (RING-type E3 ubiquitin transferase BRAP2) (Renal carcinoma antigen NY-REN-63)BRAP RNF52Q7Z5693
Bromodomain and WD repeat-containing protein 1 (WD repeat-containing protein 9)BRWD1 C21orf107 WDR9Q9NSI63
Bromodomain-containing protein 4 (Fragment)BRD4M0QZD93
BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 3 (hBACURD3) (BTB/POZ domain-containing protein KCTD10) (Potassium channel tetramerization domain-containing protein 10)KCTD10 ULR061 MSTP028Q9H3F63
BTB/POZ domain-containing protein 7BTBD7 KIAA1525Q9P2033
BTB/POZ domain-containing protein KCTD9KCTD9Q7L2733
C-Jun-amino-terminal kinase-interacting protein 1 (JIP-1) (JNK-interacting protein 1) (Islet-brain 1) (IB-1) (JNK MAP kinase scaffold protein 1) (Mitogen-activated protein kinase 8-interacting protein 1)MAPK8IP1 IB1 JIP1 PRKM8IPQ9UQF23
C-terminal binding protein 1CTBP1Q4KMQ83
C-terminal binding protein 2 (Fragment)0Q1WIS03
C-type lectin domain family 12 member A (C-type lectin-like molecule 1) (CLL-1) (Dendritic cell-associated lectin 2) (DCAL-2) (Myeloid inhibitory C-type lectin-like receptor) (MICL)CLEC12A CLL1 DCAL2 MICLQ5QGZ93
C1QTNF3-AMACR readthrough (NMD candidate)C1QTNF3-AMACRE9PGA63
Cadherin-1CDH1H3BNC63
Cadherin-1CDH1H3BVI73
Cadherin-1 (CAM 120/80) (Epithelial cadherin) (E-cadherin) (Uvomorulin) (CD antigen CD324) [Cleaved into: E-Cad/CTF1; E-Cad/CTF2; E-Cad/CTF3]CDH1 CDHE UVOA8K1U73
Cadherin-20CDH20 CDH7L3Q9HBT63
Calcium and integrin-binding family member 2 (Kinase-interacting protein 2) (KIP 2)CIB2 KIP2O758383
Calcium load-activated calcium channel (Transmembrane and coiled-coil domains 1, isoform CRA_c)TMCO1 hCG_1766418J3QQY23
Calcium permeable stress-gated cation channel 1 (Transmembrane protein 63C)TMEM63C C14orf171 CSC1Q9P1W33
Calcium-activated chloride channel regulator 2 (EC 3.4.-.-) (Calcium-activated chloride channel family member 2) (hCLCA2) (Calcium-activated chloride channel protein 3) (CaCC-3) (hCaCC-3) [Cleaved into: Calcium-activated chloride channel regulator 2, 109 kDa form; Calcium-activated chloride channel regulator 2, 35 kDa form]CLCA2 CACC3Q9UQC93
Calcium-activated potassium channel subunit beta-2 (BK channel subunit beta-2) (BKbeta2) (Hbeta2) (Calcium-activated potassium channel, subfamily M subunit beta-2) (Charybdotoxin receptor subunit beta-2) (Hbeta3) (K(VCA)beta-2) (Maxi K channel subunit beta-2) (Slo-beta-2)KCNMB2Q9Y6913
Calcium-binding and coiled-coil domain-containing protein 1 (Calphoglin) (Coiled-coil coactivator protein) (Sarcoma antigen NY-SAR-3)CALCOCO1 KIAA1536 PP13275 UNQ2436/PRO4996Q9P1Z23
Calcium-independent phospholipase A2-gamma (EC 3.1.1.5) (Intracellular membrane-associated calcium-independent phospholipase A2 gamma) (iPLA2-gamma) (PNPLA-gamma) (Patatin-like phospholipase domain-containing protein 8) (iPLA2-2)PNPLA8 IPLA22 IPLA2G BM-043Q9NP803
Calcium/calmodulin-dependent protein kinase type II subunit delta (Fragment)CAMK2DH0Y9C23
Calcyclin-binding protein (CacyBP) (hCacyBP) (S100A6-binding protein) (Siah-interacting protein)CACYBP S100A6BP SIP PNAS-107B3KSF13
CalmodulinCALM2E7EMB33
Calmodulin-3CALM3 CALML2 CAM3 CAMC CAMIIIP0DP253
Calmodulin-like protein 4 (Serologically defined breast cancer antigen NY-BR-20)CALML4Q96GE63
Calpain-1 catalytic subunit (Fragment)CAPN1E9PIA93
Calpain-15 (EC 3.4.22.-) (Small optic lobes homolog)CAPN15 SOLHO758083
Calsyntenin-1 (Fragment)CLSTN1Q5SR543
cAMP-responsive element modulator (Inducible cAMP early repressor) (ICER)CREMQ030603
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (EC 3.1.4.53) (DPDE4) (PDE32)PDE4B DPDE4Q073433
Cancer/testis antigen 1 (Autoimmunogenic cancer/testis antigen NY-ESO-1) (Cancer/testis antigen 6.1) (CT6.1) (L antigen family member 2) (LAGE-2)CTAG1A CTAG CTAG1 ESO1 LAGE2 LAGE2A; CTAG1B LAGE2BP783583
Cannabinoid receptor 2 (CB-2) (CB2) (hCB2) (CX5)CNR2 CB2A CB2BP349723
Carbohydrate sulfotransferase 13 (EC 2.8.2.5) (Chondroitin 4-O-sulfotransferase 3) (Chondroitin 4-sulfotransferase 3) (C4ST-3) (C4ST3)CHST13Q8NET63
Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 (Fragment)CTDSP1H7C2703
Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein (C-terminal PDZ ligand of neuronal nitric oxide synthase protein) (Nitric oxide synthase 1 adaptor protein)NOS1AP CAPON KIAA0464O750523
Carboxylic ester hydrolase (EC 3.1.1.-)ACHEF8WAR73
Carboxypeptidase A6 (EC 3.4.17.-)CPA6 CPAHQ8N4T03
Carboxypeptidase B2CPB2A0A087WSY53
Carboxypeptidase E (Fragment)CPEH0YAM03
Cardiotrophin-like cytokine factor 1 (B-cell-stimulating factor 3) (BSF-3) (Novel neurotrophin-1) (NNT-1)CLCF1 BSF3 CLC NNT1Q9UBD93
Carnosine synthase 1 (EC 6.3.2.11) (ATP-grasp domain-containing protein 1)CARNS1 ATPGD1 KIAA1394A5YM723
Cas scaffolding protein family member 4 (HEF-like protein) (HEF1-EFS-p130Cas-like protein) (HEPL)CASS4 C20orf32 HEFLQ9NQ753
Casein kinase II subunit beta (CK II beta) (Phosvitin) (Protein G5a)CSNK2B CK2N G5AB0UXA93
Caskin-1 (CASK-interacting protein 1)CASKIN1 KIAA1306Q8WXD93
CASP8 and FADD-like apoptosis regulator (Caspase homolog) (CASH) (Caspase-eight-related protein) (Casper) (Caspase-like apoptosis regulatory protein) (CLARP) (Cellular FLICE-like inhibitory protein) (c-FLIP) (FADD-like antiapoptotic molecule 1) (FLAME-1) (Inhibitor of FLICE) (I-FLICE) (MACH-related inducer of toxicity) (MRIT) (Usurpin) [Cleaved into: CASP8 and FADD-like apoptosis regulator subunit p43; CASP8 and FADD-like apoptosis regulator subunit p12]CFLAR CASH CASP8AP1 CLARP MRITO155193
Caspase recruitment domain-containing protein 14 (CARD-containing MAGUK protein 2) (Carma 2)CARD14 CARMA2Q9BXL63
Caspase recruitment domain-containing protein 16 (Caspase recruitment domain-only protein 1) (CARD-only protein 1) (Caspase-1 inhibitor COP) (Pseudo interleukin-1 beta converting enzyme) (Pseudo-ICE) (Pseudo-IL1B-converting enzyme)CARD16 COP COP1Q5EG053
Caspase recruitment domain-containing protein 19 (Bcl10-interacting CARD protein) (BinCARD)CARD19 C9orf89Q96LW73
Cathelicidin antimicrobial peptideCAMP hCG_18336J3KNB43
Cation-dependent mannose-6-phosphate receptor (Fragment)M6PRH0YGE93
Cationic amino acid transporter 3 (CAT-3) (CAT3) (Cationic amino acid transporter y+) (Solute carrier family 7 member 3)SLC7A3 ATRC3 CAT3Q8WY073
Caveolin (Fragment)0A9XTE53
CCR4-NOT transcription complex subunit 4 (EC 2.3.2.27) (CCR4-associated factor 4) (E3 ubiquitin-protein ligase CNOT4) (Potential transcriptional repressor NOT4Hp) (RING-type E3 ubiquitin transferase CNOT4)CNOT4 NOT4O956283
CCR4-NOT transcription complex subunit 6-like (EC 3.1.13.4) (Carbon catabolite repressor protein 4 homolog B)CNOT6L CCR4BQ96LI53
Cdc42 effector protein 5 (Binder of Rho GTPases 3)CDC42EP5 BORG3 CEP5Q6NZY73
CDC42 small effector protein 2CDC42SE2D6REL03
CDC42BPA proteinCDC42BPAB9EGA73
CDC42BPB protein (Fragment)CDC42BPBQ86XZ83
CDK-activating kinase assembly factor MAT1 (CDK7/cyclin-H assembly factor) (Cyclin-G1-interacting protein) (Menage a trois) (RING finger protein 66) (RING finger protein MAT1) (p35) (p36)MNAT1 CAP35 MAT1 RNF66P519483
CDK5 and ABL1 enzyme substrate 2 (Interactor with CDK3 2) (Ik3-2)CABLES2 C20orf150Q9BTV73
cDNA FLJ10305 fis, clone NT2RM20002390Q9NW563
cDNA FLJ10506 fis, clone NT2RP20005100Q9NVU33
cDNA FLJ10524 fis, clone NT2RP2000880, highly similar to Eukaryotic translation initiation factor 5B0B3KM863
cDNA FLJ11229 fis, clone PLACE1008356, highly similar to Homo sapiens meningioma expressed antigen 5 ((MGEA5), mRNA)0B3KMK23
cDNA FLJ11308 fis, clone PLACE1010074, highly similar to Sorting nexin-20B3KML13
cDNA FLJ12487 fis, clone NT2RM2000609, highly similar to Choline transporter-like protein 10B3KMS73
cDNA FLJ12832 fis, clone NT2RP2003137, highly similar to Ubiquitin domain-containing protein 20B3KMW83
cDNA FLJ13606 fis, clone PLACE1010579, highly similar to Homo sapiens GULP, engulfment adaptor PTB domain containing 1 (GULP1), mRNA0B3KN523
cDNA FLJ14196 fis, clone NT2RP3002330, highly similar to HBS1-like protein0B3KNB93
cDNA FLJ14631 fis, clone NT2RP2000660, highly similar to Homo sapiens fidgetin-like 1 (FIGNL1), mRNA0B3KNH63
cDNA FLJ16042 fis, clone BRAMY2021498, highly similar to ADAMTS-19 (EC 3.4.24.-)0B3KV143
cDNA FLJ16452 fis, clone BRAWH3002467, highly similar to RAB GDP DISSOCIATION INHIBITOR BETA0B3KVE33
cDNA FLJ16726 fis, clone UTERU30147910Q6ZMS33
cDNA FLJ26488 fis, clone KDN05770, highly similar to Bumetanide-sensitive sodium-(potassium)-chloride cotransporter 20Q6ZP543
cDNA FLJ27421 fis, clone WMC079810Q6ZNN73
cDNA FLJ32002 fis, clone NT2RP7009394, highly similar to Exocyst complex component 20B3KPN73
cDNA FLJ32482 fis, clone SKNMC2001324, highly similar to Importin-40B3KPY93
cDNA FLJ32715 fis, clone TESTI2000784, highly similar to Importin-40B3KQ333
cDNA FLJ33721 fis, clone BRAWH2016792, highly similar to Angiomotin-like protein 20B3KR563
cDNA FLJ34106 fis, clone FCBBF3008073, highly similar to SPLICING FACTOR, ARGININE/SERINE-RICH 70Q8NB803
cDNA FLJ34625 fis, clone KIDNE2015244, highly similar to Serine protease HTRA1 (EC 3.4.21.-)0B3KRN43
cDNA FLJ35058 fis, clone OCBBF2018707, highly similar to DIHYDROPYRIMIDINASE RELATED PROTEIN-20Q8NAN93
cDNA FLJ35376 fis, clone SKMUS2004044, highly similar to Homo sapiens ribosomal protein L3 (RPL3), transcript variant 2, mRNA0B3KS363
cDNA FLJ36526 fis, clone TRACH2003347, highly similar to NSFL1 cofactor p47 (p47 protein isoform a variant) (Fragment)0Q53FE83
cDNA FLJ36740 fis, clone UTERU2013322, highly similar to Biglycan0A6NLG93
cDNA FLJ37546 fis, clone BRCAN2027364, highly similar to Homo sapiens formin-like 2 (FMNL2), transcript variant 2, mRNA0B3KT323
cDNA FLJ38724 fis, clone KIDNE2010151, highly similar to UROMODULIN0B3KTU03
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