EVpedia provide top 100+ EV markers, selected according to their identification number.
Based on EV proteomes, we defined the identification number of protein A as the number of datasets which contain protein A.
Therefore, proteins with higher identification numbers were more conserved.

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Protein name Gene symbol UniProt accession Identification number
Coiled-coil domain-containing protein 125 (Protein kenae)CCDC125 KENAEQ86Z203
Coiled-coil domain-containing protein 138CCDC138Q96M893
Coiled-coil domain-containing protein 150CCDC150Q8NCX03
Coiled-coil domain-containing protein 175CCDC175 C14orf38P0C2213
Coiled-coil domain-containing protein 180CCDC180 C9orf174 KIAA1529Q9P1Z93
Coiled-coil domain-containing protein 191CCDC191 KIAA1407Q8NCU43
Coiled-coil domain-containing protein 65 (Testis development protein NYD-SP28)CCDC65Q8IXS23
Coiled-coil domain-containing protein 66CCDC66A2RUB63
Coiled-coil domain-containing protein 68 (Cutaneous T-cell lymphoma-associated antigen se57-1) (CTCL-associated antigen se57-1)CCDC68Q9H2F93
Coiled-coil domain-containing protein 69CCDC69A6NI793
Coiled-coil domain-containing protein 7 (Protein BIOT2)CCDC7 BIOT2 C10orf68Q96M833
Collagen alpha-1(XVIII) chain (Fragment)COL18A1H7C4573
Collagen alpha-2(IX) chainCOL9A2Q140553
Complement C1q-like protein 4 (C1q and tumor necrosis factor-related protein 11) (C1q/TNF-related protein 11)C1QL4 CTRP11Q86Z233
Complement C1r subcomponentC1RF5H1V03
Complement C1s subcomponentC1SF8WCZ63
Complement C1s subcomponent (Fragment)C1SB5MCV43
Complement C2 (cDNA FLJ54376, highly similar to Complement C2 (EC 3.4.21.43))C2B4DQI13
Complement C4-A (Acidic complement C4) (C3 and PZP-like alpha-2-macroglobulin domain-containing protein 2) [Cleaved into: Complement C4 beta chain; Complement C4-A alpha chain; C4a anaphylatoxin; C4b-A; C4d-A; Complement C4 gamma chain]C4A CO4 CPAMD2B2RUT63
Complement C4-B (Basic complement C4) (C3 and PZP-like alpha-2-macroglobulin domain-containing protein 3) [Cleaved into: Complement C4 beta chain; Complement C4-B alpha chain; C4a anaphylatoxin; C4b-B; C4d-B; Complement C4 gamma chain]C4B CO4 CPAMD3; C4B_2A2BHY43
Complement C4-B (Basic complement C4) (C3 and PZP-like alpha-2-macroglobulin domain-containing protein 3) [Cleaved into: Complement C4 beta chain; Complement C4-B alpha chain; C4a anaphylatoxin; C4b-B; C4d-B; Complement C4 gamma chain]C4B CO4 CPAMD3; C4B_2Q6U2G13
Complement component C1q receptor (C1q/MBL/SPA receptor) (C1qR) (C1qR(p)) (C1qRp) (CDw93) (Complement component 1 q subcomponent receptor 1) (Matrix-remodeling-associated protein 4) (CD antigen CD93)CD93 C1QR1 MXRA4Q9NPY33
Complement component C8 gamma chain (Fragment)C8GQ5SQ083
Complement factor DCFDK7ERG93
Complex I assembly factor TIMMDC1, mitochondrial (Protein M5-14) (Translocase of inner mitochondrial membrane domain-containing protein 1) (TIMM domain containing-protein 1)TIMMDC1 C3orf1 UNQ247/PRO284Q9NPL83
Complexin-2 (Complexin II) (CPX II) (Synaphin-1)CPLX2Q6PUV43
Condensin complex subunit 10B3KY033
Conserved oligomeric Golgi complex subunit 4COG4H3BMV93
ConsortinCNST C1orf71Q6PJW83
Contactin-4 (Brain-derived immunoglobulin superfamily protein 2) (BIG-2)CNTN4Q8IWV23
Contactin-6 (Neural recognition molecule NB-3) (hNB-3)CNTN6Q9UQ523
COP9 signalosome complex subunit 3 (Fragment)COPS3C9JLV53
COP9 signalosome complex subunit 9 (CSN acidic protein) (CSNAP) (Myeloma-overexpressed gene 2 protein)COPS9 MYEOV2Q8WXC63
Copper-transporting ATPase 2 (EC 3.6.3.54) (Copper pump 2) (Wilson disease-associated protein) [Cleaved into: WND/140 kDa]ATP7B PWD WC1 WNDP356703
CorneodesmosinCDSNG8JLG23
CornifelinCNFNQ9BYD53
CoroninCORO7-PAM16 PAM16A0A0A6YYL43
Coronin-1C (Coronin-3) (hCRNN4)CORO1C CRN2 CRNN4A7MAP13
Coronin-1C (Fragment)CORO1CH0YHL73
Cortactin isoform a variant (Fragment)0Q53HG73
Corticoliberin (Corticotropin-releasing factor) (CRF) (Corticotropin-releasing hormone)CRHP068503
COUP transcription factor 2 (COUP-TF2) (Apolipoprotein A-I regulatory protein 1) (ARP-1) (COUP transcription factor II) (COUP-TF II) (Nuclear receptor subfamily 2 group F member 2)NR2F2 ARP1 TFCOUP2P244683
CROP protein (Fragment)CROPQ6PKC23
Cryocrystalglobulin CC1 heavy chain variable region (Fragment)0B1N7B63
CUB and sushi domain-containing protein 2 (CUB and sushi multiple domains protein 2)CSMD2 KIAA1884Q7Z4083
Cullin-1CUL1A0A0C4DGX43
Cullin-7 (CUL-7)CUL7 KIAA0076Q149993
CXXC-type zinc finger protein 1 (CpG-binding protein) (PHD finger and CXXC domain-containing protein 1)CXXC1 CFP1 CGBP PCCX1 PHF18Q9P0U43
Cyclic AMP-dependent transcription factor ATF-2 (cAMP-dependent transcription factor ATF-2) (EC 2.3.1.48) (Activating transcription factor 2) (Cyclic AMP-responsive element-binding protein 2) (CREB-2) (cAMP-responsive element-binding protein 2) (HB16) (Histone acetyltransferase ATF2) (cAMP response element-binding protein CRE-BP1)ATF2 CREB2 CREBP1P153363
Cyclic AMP-dependent transcription factor ATF-6 alpha (cAMP-dependent transcription factor ATF-6 alpha) (Activating transcription factor 6 alpha) (ATF6-alpha) [Cleaved into: Processed cyclic AMP-dependent transcription factor ATF-6 alpha]ATF6P188503
Cyclic AMP-responsive element-binding protein 5 (CREB-5) (cAMP-responsive element-binding protein 5) (CRE-BPa)CREB5 CREBPAQ029303
Cyclic nucleotide-gated cation channel beta-1 (Cyclic nucleotide-gated cation channel 4) (CNG channel 4) (CNG-4) (CNG4) (Cyclic nucleotide-gated cation channel gamma) (Cyclic nucleotide-gated cation channel modulatory subunit) (Cyclic nucleotide-gated channel beta-1) (CNG channel beta-1) (Glutamic acid-rich protein) (GARP)CNGB1 CNCG2 CNCG3L CNCG4 RCNC2Q140283
Cyclin-C (SRB11 homolog) (hSRB11)CCNCP248633
Cyclin-dependent kinase 9CDK9B5BU533
Cyclin-H (MO15-associated protein) (p34) (p37)CCNHP519463
Cyclin-ICCNIQ140943
Cystatin-SA (Cystatin-2) (Cystatin-S5)CST2P092283
Cysteine protease ATG4C (EC 3.4.22.-) (AUT-like 3 cysteine endopeptidase) (Autophagin-3) (Autophagy-related cysteine endopeptidase 3) (Autophagy-related protein 4 homolog C)ATG4C APG4C AUTL1 AUTL3Q96DT63
Cysteine-rich C-terminal protein 1 (Protein NICE-1)CRCT1 C1orf42 NICE1Q9UGL93
Cysteinyl-tRNA synthetase, isoform CRA_b (cDNA FLJ38994 fis, clone NT2RI2009259, highly similar to Cysteinyl-tRNA synthetase (EC 6.1.1.16))CARS hCG_16441A8MVQ33
Cystic fibrosis transmembrane conductance regulator (CFTR) (ATP-binding cassette sub-family C member 7) (Channel conductance-controlling ATPase) (EC 3.6.3.49) (cAMP-dependent chloride channel)CFTR ABCC7P135693
CystinosinCTNSO609313
Cytochrome b-c1 complex subunit 2, mitochondrialUQCRC2H3BRG43
Cytochrome b-c1 complex subunit 7UQCRBE5RHG93
Cytochrome b561 domain-containing protein 2 (Putative tumor suppressor protein 101F6)CYB561D2 101F6 LUCA12.2O145693
Cytochrome c oxidase assembly factor 4 homolog, mitochondrial (Coiled-coil-helix-coiled-coil-helix domain-containing protein 8) (E2-induced gene 2 protein)COA4 CHCHD8 E2IG2Q9NYJ13
Cytochrome c oxidase subunit 2COX2C8YBL13
Cytochrome P450 20A1CYP20A1E9PHG53
Cytochrome P450 2U1 (EC 1.14.14.1)CYP2U1Q7Z4493
Cytochrome P450 4B1 (EC 1.14.14.1) (CYPIVB1) (Cytochrome P450-HP)CYP4B1P135843
Cytohesin-1 (PH, SEC7 and coiled-coil domain-containing protein 1) (SEC7 homolog B2-1)CYTH1 D17S811E PSCD1Q154383
Cytohesin-4 (PH, SEC7 and coiled-coil domain-containing protein 4)CYTH4 CYT4 PSCD4Q9UIA03
Cytokine receptor-like factor 1 (Cytokine-like factor 1) (CLF-1) (ZcytoR5)CRLF1 UNQ288/PRO327O754623
Cytoplasmic dynein 1 intermediate chain 2 (Fragment)DYNC1I2E7EQL53
Cytoplasmic dynein 1 light intermediate chain 1DYNC1LI1E9PHI63
Cytoplasmic linker protein CLIP-170 (Fragment)CLIP-170O436673
Cytoplasmic phosphatidylinositol transfer protein 1 (Mammalian rdgB homolog beta) (M-rdgB beta) (MrdgBbeta) (Retinal degeneration B homolog beta) (RdgBbeta)PITPNC1J3QR203
Cytoskeleton-associated protein 2-like (Radial fiber and mitotic spindle protein) (Radmis)CKAP2LQ8IYA63
Cytosolic arginine sensor for mTORC1 subunit 2 (Cellular arginine sensor for mTORC1 protein 2) (GATS-like protein 2)CASTOR2 GATSL1 GATSL2A6NHX03
Cytosolic carboxypeptidase 1 (EC 3.4.17.-) (ATP/GTP-binding protein 1) (Nervous system nuclear protein induced by axotomy protein 1 homolog)AGTPBP1 CCP1 KIAA1035 NNA1Q9UPW53
Cytosolic carboxypeptidase 4 (EC 3.4.17.-) (ATP/GTP-binding protein-like 1)AGBL1 CCP4Q96MI93
Cytosolic Fe-S cluster assembly factor NARFL (Iron-only hydrogenase-like protein 1) (IOP1) (Nuclear prelamin A recognition factor-like protein) (Protein related to Narf)NARFL PRNQ9H6Q43
D-dopachrome tautomerase (D-dopachrome tautomerase 1) (D-dopachrome tautomerase, isoform CRA_b) (cDNA FLJ76419, highly similar to Homo sapiens D-dopachrome tautomerase (DDT), mRNA)DDT DDT1 hCG_41098Q53Y513
DEAD (Asp-Glu-Ala-As) box polypeptide 19 variant (Fragment)0Q53G163
DEAD (Asp-Glu-Ala-Asp) box polypeptide 24 variant (Fragment)0Q59FS73
Decapping and exoribonuclease protein (DXO) (EC 3.1.13.-) (EC 3.6.1.-) (Dom-3 homolog Z)DXO DOM3L DOM3Z NG6O779323
Dedicator of cytokinesis protein 4DOCK4 KIAA0716Q8N1I03
Defensin-5 (Defensin, alpha 5) (HD5(20-94)) [Cleaved into: HD5(23-94); HD5(29-94); HD5(56-94); HD5(63-94)]DEFA5 DEF5Q015233
Delta-type opioid receptor (D-OR-1) (DOR-1)OPRD1 OPRDP411433
DENN domain-containing protein 2ADENND2A KIAA1277Q9ULE33
DENN domain-containing protein 5B (Rab6IP1-like protein)DENND5BQ6ZUT93
Deoxyribonuclease0Q5TZW23
DEP domain-containing protein 1B (HBV X-transactivated gene 8 protein) (HBV XAg-transactivated protein 8)DEPDC1B XTP8Q8WUY93
Desmocollin 1, isoform CRA_b (Desmocollin 1b)DSC1 hCG_25474Q9HB003
Desmoglein-4 (Cadherin family member 13)DSG4 CDHF13Q86SJ63
Desumoylating isopeptidase 1 (DeSI-1) (EC 3.4.-.-) (PPPDE peptidase domain-containing protein 2) (Protein FAM152B)DESI1 FAM152B PPPDE2Q6ICB03
Diacylglycerol O-acyltransferase 1 (EC 2.3.1.20) (ACAT-related gene product 1) (Acyl-CoA retinol O-fatty-acyltransferase) (ARAT) (Retinol O-fatty-acyltransferase) (EC 2.3.1.76) (Diglyceride acyltransferase)DGAT1 AGRP1 DGATO759073
Diazepam binding inhibitor, splice form 1D(2)DBIB8ZWD93
Diffuse panbronchiolitis critical region protein 1DPCR1 C6orf37 PBLTQ3MIW93
Dihydrolipoyl dehydrogenase (EC 1.8.1.4)0B4DFL13
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