EVpedia provide top 100+ EV markers, selected according to their identification number.
Based on EV proteomes, we defined the identification number of protein A as the number of datasets which contain protein A.
Therefore, proteins with higher identification numbers were more conserved.

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Protein name Gene symbol UniProt accession Identification number
Epididymis secretory protein Li 297 (Putative uncharacterized protein)HEL-S-297Q86Z223
ER lumen protein-retaining receptor 3 (KDEL endoplasmic reticulum protein retention receptor 3) (KDEL receptor 3)KDELR3O437313
Ermin (Juxtanodin) (JN)ERMN KIAA1189Q8TAM63
Erythrocyte band 7 integral membrane protein (Protein 7.2b) (Stomatin)STOM BND7 EPB72B1AM773
Espin-like proteinESPNLQ6ZVH73
Estradiol 17-beta-dehydrogenase 11HSD17B11D6RCD03
Ethanolamine-phosphate phospho-lyase (EC 4.2.3.2) (Alanine--glyoxylate aminotransferase 2-like 1)ETNPPL AGXT2L1Q8TBG43
ETS-related transcription factor Elf-2 (E74-like factor 2) (New ETS-related factor)ELF2 NERFQ157233
Eukaryotic initiation factor 4A-I (Fragment)EIF4A1J3QKZ93
Eukaryotic initiation factor 4A-I (Fragment)EIF4A1J3QR643
Eukaryotic initiation factor 4AI (Fragment)EIF4A1Q9NZR93
Eukaryotic translation elongation factor 1 alpha 2 variant (Fragment)0Q59GP53
Eukaryotic translation elongation factor 1 epsilon-1 (Aminoacyl tRNA synthetase complex-interacting multifunctional protein 3) (Elongation factor p18) (Multisynthase complex auxiliary component p18)EEF1E1 AIMP3 P18C9JLK53
Eukaryotic translation initiation factor 1A, Y-chromosomalEIF1AYA6NJH93
Eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa (Eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa, isoform CRA_b) (cDNA, FLJ93495, highly similar to Homo sapiens eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa (EIF2S2), mRNA) (eIF2S2 protein)EIF2S2 hCG_2018881Q6IBR83
Eukaryotic translation initiation factor 2-alpha kinase 1 (EC 2.7.11.1) (Heme-controlled repressor) (HCR) (Heme-regulated eukaryotic initiation factor eIF-2-alpha kinase) (Heme-regulated inhibitor) (Hemin-sensitive initiation factor 2-alpha kinase)EIF2AK1 HRI KIAA1369 PRO1362Q9BQI33
Eukaryotic translation initiation factor 2A (eIF-2A) (65 kDa eukaryotic translation initiation factor 2A) [Cleaved into: Eukaryotic translation initiation factor 2A, N-terminally processed]EIF2A CDA02 MSTP004 MSTP089B4DF963
Eukaryotic translation initiation factor 3 subunit E (eIF3e) (Eukaryotic translation initiation factor 3 subunit 6) (eIF-3 p48)EIF3E EIF3S6 INT6E5RGA23
Eukaryotic translation initiation factor 3 subunit E (Fragment)EIF3EE5RIT43
Eukaryotic translation initiation factor 3 subunit E (Fragment)EIF3EH0YAW43
Eukaryotic translation initiation factor 3 subunit KEIF3KK7ES313
Eukaryotic translation initiation factor 3 subunit M (Fragment)EIF3MJ3KNJ23
Eukaryotic translation initiation factor 4EEIF4ED6RBW13
Eukaryotic translation initiation factor 5A (eIF-5A)EIF5A2F8WCJ13
Eukaryotic translation initiation factor 5BEIF5BA0A087WUT63
Excitatory amino acid transporter 4 (Sodium-dependent glutamate/aspartate transporter) (Solute carrier family 1 member 6)SLC1A6 EAAT4P486643
EXOC4 proteinEXOC4Q8TAR23
Exocyst complex component 3EXOC3D6RB593
Exonuclease 3'-5' domain-containing protein 2 (EC 3.1.11.1) (Exonuclease 3'-5' domain-like-containing protein 2)EXD2 C14orf114 EXDL2Q9NVH03
Exonuclease mut-7 homolog (EC 3.1.-.-) (Exonuclease 3'-5' domain-containing protein 3)EXD3 HBE269Q8N9H83
Exostosin-like 3 (EC 2.4.1.223) (EXT-related protein 1) (Glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase) (Hereditary multiple exostoses gene isolog) (Multiple exostosis-like protein 3) (Putative tumor suppressor protein EXTL3)EXTL3 EXTL1L EXTR1 KIAA0519O439093
Exportin-1XPO1F8WF713
Exportin-1 (Fragment)XPO1C9JF493
F-box only protein 5 (Early mitotic inhibitor 1)FBXO5 EMI1 FBX5Q9UKT43
FABP1 protein (Fragment)FABP1Q05CP73
FAD-dependent oxidoreductase domain-containing protein 1 (EC 1.-.-.-)FOXRED1 FP634Q96CU93
FAD-linked sulfhydryl oxidase ALR (EC 1.8.3.2) (Augmenter of liver regeneration) (hERV1) (Hepatopoietin)GFER ALR HERV1 HPOP557893
FAM171B protein (Fragment)FAM171BB3LEU93
Fanconi anemia group D2 protein (Protein FACD2)FANCD2 FACDQ9BXW93
Fanconi anemia group M protein (Protein FACM) (EC 3.6.4.13) (ATP-dependent RNA helicase FANCM) (Fanconi anemia-associated polypeptide of 250 kDa) (FAAP250) (Protein Hef ortholog)FANCM KIAA1596Q8IYD83
Fascin (55 kDa actin-bundling protein) (Singed-like protein) (p55)FSCN1 FAN1 HSN SNLQ96IH13
FAST kinase domain-containing protein 2, mitochondrialFASTKD2 KIAA0971Q9NYY83
FAST kinase domain-containing protein 5, mitochondrialFASTKD5 KIAA1792Q7L8L63
Fatty acid-binding protein, heart (Fragment)FABP3S4R3713
FBRNPD10S102Q65ZQ33
Fer-1-like protein 4FER1L4 C20orf124A9Z1Z33
FERM domain-containing protein 1FRMD1Q8N8783
FERM domain-containing protein 3 (Band 4.1-like protein 4O) (Ovary type protein 4.1) (4.1O)FRMD3 EPB41L4OA2A2Y43
Ferredoxin-2, mitochondrial (Adrenodoxin-like protein) (Ferredoxin-1-like protein)FDX2 FDX1LQ6P4F23
FerritinFTLQ6S4P33
Fibrinogen gamma chain (Fragment)FGGC9JPQ93
Fibroblast growth factor 18 (FGF-18) (zFGF5)FGF18 UNQ420/PRO856O760933
Fibrosin-1-like protein (AUTS2-like protein) (HBV X-transactivated gene 9 protein) (HBV XAg-transactivated protein 9)FBRSL1 AUTS2L KIAA1545 XTP9Q9HCM73
Filamin AFLNAA6NDY93
Filamin-A (Fragment)FLNAF8WE983
Filamin-binding LIM protein 1 (FBLP-1) (Migfilin) (Mitogen-inducible 2-interacting protein) (MIG2-interacting protein)FBLIM1 FBLP1Q8WUP23
FLJ00064 protein (Fragment)FLJ00064Q9H7K83
FLJ00279 protein (Fragment)FLJ00279Q6ZNL43
Flotillin-1 (Fragment)FLOT1A2AB093
Folate receptor alpha isoform (Fragment)0Q96QD13
Folate receptor beta (FR-beta) (Folate receptor 2) (Folate receptor, fetal/placental) (Placental folate-binding protein) (FBP)FOLR2P142073
Four and a half LIM domains protein 1 (Fragment)FHL1Q5JXI83
Fructose 1,6-bisphosphatase (Fragment)0A8QID03
Fructose-bisphosphate aldolase (EC 4.1.2.13)0A8K4303
FSD1-like protein (Coiled-coil domain-containing protein 10) (FSD1 N-terminal-like protein)FSD1L CCDC10 CSDUFD1 FSD1CL FSD1NLQ9BXM93
Fukutin (EC 2.-.-.-) (Fukuyama-type congenital muscular dystrophy protein)FKTN FCMDO750723
Fukutin-related protein (EC 2.-.-.-)FKRPQ9H9S53
FYVE, RhoGEF and PH domain-containing protein 2 (Zinc finger FYVE domain-containing protein 4)FGD2 ZFYVE4Q7Z6J43
G protein-coupled receptor kinase interactor 1 variant (Fragment)0Q59FC33
G-gamma globin Paulinia variantHBG2D3GKD93
G-protein coupled receptor 161 (G-protein coupled receptor RE2)GPR161Q8N6U83
G-protein coupled receptor 183 (Epstein-Barr virus-induced G-protein coupled receptor 2) (EBI2) (EBV-induced G-protein coupled receptor 2) (hEBI2)GPR183 EBI2P322493
G-protein coupled receptor 39GPR39O431943
G2/mitotic-specific cyclin-B2CCNB2O950673
G2/mitotic-specific cyclin-B3CCNB3 CYCB3Q8WWL73
Galactoside-binding soluble lectin 13 (Galectin-13) (Gal-13) (Placental tissue protein 13) (PP13) (Placental protein 13)LGALS13 PLAC8Q9UHV83
GametogenetinGGNQ86UU53
Gamma-aminobutyric acid receptor subunit beta-2 (GABA(A) receptor subunit beta-2)GABRB2P478703
Gamma-aminobutyric acid receptor-associated protein-like 2GABARAPL2H3BSM53
Gamma-crystallin D (Gamma-D-crystallin) (Gamma-crystallin 4)CRYGD CRYG4P073203
Gamma-enolase (EC 4.2.1.11) (2-phospho-D-glycerate hydro-lyase) (Enolase 2) (Neural enolase) (Neuron-specific enolase) (NSE)ENO2B7Z2X93
Gamma-enolase (Fragment)ENO2F5H1C33
Gamma-G globin (Fragment)0Q144033
Gamma-glutamyltransferase light chain 2 (Gamma-glutamyltransferase-like protein 4)GGTLC2 GGTL4Q143903
Gamma-glutamyltranspeptidase 1 (Fragment)GGT1E7ETR73
Gamma-tubulin complex component 2 (GCP-2) (hGCP2) (Gamma-ring complex protein 103 kDa) (h103p) (hGrip103) (Spindle pole body protein Spc97 homolog) (hSpc97)TUBGCP2 GCP2B4DM183
Ganglioside-induced differentiation-associated protein 2GDAP2Q9NXN43
Gap junction alpha-10 protein (Connexin-62) (Cx62)GJA10 CX62Q969M23
Gastric cancer hepatocellular carcinoma suppressor 1 variantHCCS1B1AA173
Gastrotropin (GT) (Fatty acid-binding protein 6) (Ileal lipid-binding protein) (ILBP) (Intestinal 15 kDa protein) (I-15P) (Intestinal bile acid-binding protein) (I-BABP)FABP6 ILBP ILLBPP511613
Gelsolin (Fragment)GSNQ5T0I13
General transcription factor IIH subunit 2-like protein (General transcription factor IIH polypeptide 2-like protein)GTF2H2C; GTF2H2C_2 GTF2H2DQ6P1K83
General transcription factor IIH subunit 3 (Basic transcription factor 2 34 kDa subunit) (BTF2 p34) (General transcription factor IIH polypeptide 3) (TFIIH basal transcription factor complex p34 subunit)GTF2H3Q138893
Genetic suppressor element 1GSE1 KIAA0182Q146873
Globin B3 (Hemoglobin, epsilon 1)HBE1 GLNB3D9YZU73
Glucocorticoid receptor (GR) (Nuclear receptor subfamily 3 group C member 1)NR3C1 GRLP041503
Glucose phosphate isomerase variant (Fragment)0Q59F853
Glucose-6-phosphate exchanger SLC37A4 (Glucose-5-phosphate transporter) (Glucose-6-phosphate translocase) (Solute carrier family 37 member 4) (Transformation-related gene 19 protein) (TRG-19)SLC37A4 G6PT G6PT1 PRO0685 TRG19O438263
Glucose-fructose oxidoreductase domain-containing protein 1 (EC 1.-.-.-)GFOD1 C6orf114Q9NXC23
Glucosylceramidase (EC 3.2.1.45)0B7Z6S93
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