EVpedia provide top 100+ EV markers, selected according to their identification number.
Based on EV proteomes, we defined the identification number of protein A as the number of datasets which contain protein A.
Therefore, proteins with higher identification numbers were more conserved.

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Protein name Gene symbol UniProt accession Identification number
Glutamate receptor 3 (GluR-3) (AMPA-selective glutamate receptor 3) (GluR-C) (GluR-K3) (Glutamate receptor ionotropic, AMPA 3) (GluA3)GRIA3 GLUR3 GLURCP422633
Glutamate receptor 4 (GluR-4) (GluR4) (AMPA-selective glutamate receptor 4) (GluR-D) (Glutamate receptor ionotropic, AMPA 4) (GluA4)GRIA4 GLUR4P480583
Glutamate receptor ionotropic, kainate 3 (GluK3) (Excitatory amino acid receptor 5) (EAA5) (Glutamate receptor 7) (GluR-7) (GluR7)GRIK3 GLUR7A9Z1Z83
Glutamate-rich protein 4ERICH4 C19orf69A6NGS23
Glutamyl-tRNA(Gln) amidotransferase subunit B, mitochondrial (Glu-AdT subunit B) (EC 6.3.5.-) (Cytochrome c oxidase assembly factor PET112 homolog)GATB PET112 PET112L HSPC199O758793
Glutathione S-transferase (EC 2.5.1.18)GSTM2E9PHN63
Glutathione S-transferase (EC 2.5.1.18)GSTM3A0A0A0MTN33
Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) (EC 1.2.1.12) (Peptidyl-cysteine S-nitrosylase GAPDH) (EC 2.6.99.-)GAPDH GAPD CDABP0047 OK/SW-cl.12E7EUT43
Glycerol kinase 3 (GK 3) (Glycerokinase 3) (EC 2.7.1.30) (ATP:glycerol 3-phosphotransferase 3) (Glycerol kinase 3 pseudogene) (Glycerol kinase, testis specific 1)GK3P GKP3 GKTBQ144093
Glycogen synthase kinase-3 alphaGSK3AA8MT373
Glycogen [starch] synthase (EC 2.4.1.11)0A8K6K73
Glycogen [starch] synthase, liver (EC 2.4.1.11)GYS2P548403
Glycolipid transfer proteinGLTPF5H0U53
Glycophorin-A (MN sialoglycoprotein) (PAS-2) (Sialoglycoprotein alpha) (CD antigen CD235a)GYPA GPAB8Q1853
Glycosaminoglycan xylosylkinase (EC 2.7.1.-) (Xylose kinase)FAM20B KIAA0475O750633
Glyoxalase domain-containing protein 4 (Fragment)GLOD4I3L3Q43
Glypican-1 (Fragment)GPC1H7BZL43
GNAS complex locusGNASQ5FWY23
Golgi transport 1 homolog B (S. cerevisiae), isoform CRA_c (Vesicle transport protein GOT1B)GOLT1B hCG_25051G3V1U53
Golgin subfamily A member 1 (Golgin-97)GOLGA1Q928053
Golgin subfamily A member 8JGOLGA8JA6NMD23
Golgin subfamily B member 1 (372 kDa Golgi complex-associated protein) (GCP372) (Giantin) (Macrogolgin)GOLGB1F1T0J23
GON-4-like protein (GON-4 homolog)GON4L GON4 KIAA1606Q3T8J93
Granulins (Fragment)GRNK7EMR13
Granulins (Proepithelin) (PEPI) [Cleaved into: Acrogranin (Glycoprotein of 88 Kda) (GP88) (Glycoprotein 88) (Progranulin); Paragranulin; Granulin-1 (Granulin G); Granulin-2 (Granulin F); Granulin-3 (Granulin B); Granulin-4 (Granulin A); Granulin-5 (Granulin C); Granulin-6 (Granulin D); Granulin-7 (Granulin E)]GRNQ53HQ83
Granzyme M (EC 3.4.21.-) (Met-1 serine protease) (Hu-Met-1) (Met-ase) (Natural killer cell granular protease)GZMM MET1P511243
Gremlin-2 (Cysteine knot superfamily 1, BMP antagonist 2) (DAN domain family member 3) (Protein related to DAN and cerberus)GREM2 CKTSF1B2 DAND3 PRDCQ9H7723
GRIP and coiled-coil domain containing 2, isoform CRA_aGCC2 hCG_26654D3DX703
Group IID secretory phospholipase A2 (GIID sPLA2) (sPLA2-IID) (EC 3.1.1.4) (PLA2IID) (Phosphatidylcholine 2-acylhydrolase 2D) (Secretory-type PLA, stroma-associated homolog)PLA2G2D SPLASHQ9UNK43
Growth factor receptor-bound protein 10 (GRB10 adapter protein) (Insulin receptor-binding protein Grb-IR)GRB10 GRBIR KIAA0207Q133223
Growth/differentiation factor 8 (GDF-8) (Myostatin)MSTN GDF8O147933
GSK3B protein (GSK3beta isoform) (Glycogen synthase kinase 3 beta, isoform CRA_b) (cDNA FLJ75266, highly similar to Homo sapiens glycogen synthase kinase 3 beta, mRNA)GSK3B hCG_1818062Q6FI273
GTP-binding nuclear protein Ran (Fragment)RANF5H0183
GTP-binding protein Di-Ras3 (Distinct subgroup of the Ras family member 3) (Rho-related GTP-binding protein RhoI)DIRAS3 ARHI NOEY2 RHOIO956613
GTP-binding protein Rit1 (Fragment)RIT1V9GYC33
GTPase IMAP family member 5 (Immunity-associated nucleotide 4-like 1 protein) (Immunity-associated nucleotide 5 protein) (IAN-5) (hIAN5) (Immunity-associated protein 3)GIMAP5 IAN4L1 IAN5 IMAP3Q96F153
GTPase IMAP family member 7 (Immunity-associated nucleotide 7 protein) (IAN-7)GIMAP7 IAN7Q8NHV13
Guanine deaminaseGDAQ5SZC63
Guanine nucleotide exchange factor for Rab-3A (Rab-3A-interacting-like protein 1) (Rab3A-interacting-like protein 1) (Rabin3-like 1)RAB3IL1Q8TBN03
Guanine nucleotide-binding protein G(i) subunit alpha-2 (Adenylate cyclase-inhibiting G alpha protein)GNAI2 GNAI2BB3KTZ03
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2GNB2E7EP323
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 (Fragment)GNB2C9JIS13
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 (G protein subunit beta-2) (Transducin beta chain 2)GNB2B3KPU13
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 (Transducin beta chain 3)GNB3Q96B713
Guanine nucleotide-binding protein G(s) subunit alpha isoforms short (Fragment)GNASQ5JWE93
Guanylate cyclase activator 2B [Cleaved into: Guanylate cyclase C-activating peptide 2 (Guanylate cyclase C-activating peptide II) (GCAP-II); Uroguanylin (UGN)]GUCA2BQ166613
Guanylate-binding protein 4 (EC 3.6.5.-) (GTP-binding protein 4) (GBP-4) (Guanine nucleotide-binding protein 4)GBP4Q96PP93
Harmonin (Antigen NY-CO-38/NY-CO-37) (Autoimmune enteropathy-related antigen AIE-75) (Protein PDZ-73) (Renal carcinoma antigen NY-REN-3) (Usher syndrome type-1C protein)USH1C AIE75Q9Y6N93
HAUS augmin-like complex subunit 4HAUS4 C14orf94Q9H6D73
HCG2022736, isoform CRA_ahCG_2022736D3DN773
HCG2043239 (Immunoglobulin lambda variable 3-9 (gene/pseudogene)) (Fragment)IGLV3-9 hCG_2043239A0A075B6K53
HCG27698, isoform CRA_e (MSTP162)MST162 hCG_27698Q7Z4B13
Heat shock protein 75 kDa, mitochondrial (HSP 75) (TNFR-associated protein 1) (Tumor necrosis factor type 1 receptor-associated protein) (TRAP-1)TRAP1 HSP75F5H8973
Heat shock protein beta-6HSPB6K7EP043
Heat shock protein beta-8 (HspB8) (Alpha-crystallin C chain) (E2-induced gene 1 protein) (Protein kinase H11) (Small stress protein-like protein HSP22)HSPB8 CRYAC E2IG1 HSP22 PP1629Q9UJY13
Heat-stable enterotoxin receptor (STA receptor) (hSTAR) (EC 4.6.1.2) (Guanylyl cyclase C) (GC-C) (Intestinal guanylate cyclase)GUCY2C GUC2C STARP250923
HEBP2 protein (Fragment)HEBP2Q05DB43
HemK methyltransferase family member 2 (EC 2.1.1.-) (M.HsaHemK2P) (N(6)-adenine-specific DNA methyltransferase 1)N6AMT1 C21orf127 HEMK2 PRED28Q9Y5N53
Hemoglobin alpha-1 globin chain (Fragment)HBA1E9M4D43
Heparan-sulfate 6-O-sulfotransferase 1 (HS6ST-1) (EC 2.8.2.-)HS6ST1 HS6STO602433
Heparan-sulfate 6-O-sulfotransferase 3 (HS6ST-3) (EC 2.8.2.-)HS6ST3Q8IZP73
Heparin-binding protein HBp150Q7Z4W83
Hepatic triacylglycerol lipase (HL) (Hepatic lipase) (EC 3.1.1.3) (Lipase member C)LIPC HTGLP111503
Hepatitis B virus receptor binding protein (Fragment)0Q6PYX13
Hepatocyte cell adhesion molecule (Protein hepaCAM)HEPACAMQ14CZ83
Hermansky-Pudlak syndrome 4 protein (Light-ear protein homolog)HPS4 KIAA1667Q9NQG73
Heterochromatin protein 1-binding protein 3 (Fragment)HP1BP3B0QZK43
Heterochromatin protein 1-binding protein 3 (Fragment)HP1BP3Q5SWC83
Heterogeneous nuclear ribonucleoprotein A/BHNRNPABD6RBZ03
Heterogeneous nuclear ribonucleoprotein A/BHNRNPABD6RD183
Heterogeneous nuclear ribonucleoprotein D0 (Fragment)HNRNPDD6RF443
Heterogeneous nuclear ribonucleoprotein K (Fragment)HNRNPKQ5T6W23
Heterogeneous nuclear ribonucleoprotein MHNRNPMA0A087X0X33
Hexokinase-2HK2E9PB903
High mobility group nucleosome-binding domain-containing protein 3 (Thyroid receptor-interacting protein 7) (TR-interacting protein 7) (TRIP-7)HMGN3 TRIP7 PNAS-24Q156513
High mobility group nucleosome-binding domain-containing protein 5 (Nucleosome-binding protein 1)HMGN5 NSBP1P829703
HIP1 protein (Fragment)HIP1A4VCI63
Hippocalcin-like protein 4 (HLP4)HPCAL4Q9UM193
Histo-blood group ABO system transferase (Fucosylglycoprotein 3-alpha-galactosyltransferase) (Fucosylglycoprotein alpha-N-acetylgalactosaminyltransferase) (Glycoprotein-fucosylgalactoside alpha-N-acetylgalactosaminyltransferase) (EC 2.4.1.40) (Glycoprotein-fucosylgalactoside alpha-galactosyltransferase) (EC 2.4.1.37) (Histo-blood group A transferase) (A transferase) (Histo-blood group B transferase) (B transferase) (NAGAT) [Cleaved into: Fucosylglycoprotein alpha-N-acetylgalactosaminyltransferase soluble form]ABOP164423
Histone deacetylase (EC 3.5.1.98)0B3KUJ53
Histone deacetylase 1 (Fragment)HDAC1Q5TEE23
Histone H2BHIST1H2BI HIST1H2BC HIST1H2BE HIST1H2BF HIST1H2BG hCG_1640484 hCG_1640985 hCG_1641780 hCG_1787353 hCG_1787365B2R4S93
Histone-lysine N-methyltransferase EHMT2EHMT2A2ABF83
Histone-lysine N-methyltransferase EHMT2 (EC 2.1.1.-) (EC 2.1.1.43) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Lysine N-methyltransferase 1C) (Protein G9a)EHMT2 BAT8 C6orf30 G9A KMT1C NG36Q96KQ73
Histone-lysine N-methyltransferase PRDM9 (EC 2.1.1.43) (PR domain zinc finger protein 9) (PR domain-containing protein 9)PRDM9 PFM6Q9NQV73
Histone-lysine N-methyltransferase SETD1A (EC 2.1.1.43) (Lysine N-methyltransferase 2F) (SET domain-containing protein 1A) (hSET1A) (Set1/Ash2 histone methyltransferase complex subunit SET1)SETD1A KIAA0339 KMT2F SET1 SET1AO150473
Histone-lysine N-methyltransferase SETD2 (EC 2.1.1.43) (HIF-1) (Huntingtin yeast partner B) (Huntingtin-interacting protein 1) (HIP-1) (Huntingtin-interacting protein B) (Lysine N-methyltransferase 3A) (SET domain-containing protein 2) (hSET2) (p231HBP)SETD2 HIF1 HYPB KIAA1732 KMT3A SET2 HSPC069Q9BYW23
Histone-lysine N-methyltransferase SETDB1 (EC 2.1.1.43) (ERG-associated protein with SET domain) (ESET) (Histone H3-K9 methyltransferase 4) (H3-K9-HMTase 4) (Lysine N-methyltransferase 1E) (SET domain bifurcated 1)SETDB1 KIAA0067 KMT1EQ150473
Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (Androgen receptor coactivator 267 kDa protein) (Androgen receptor-associated protein of 267 kDa) (H3-K36-HMTase) (H4-K20-HMTase) (Lysine N-methyltransferase 3B) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein)NSD1 ARA267 KMT3BQ96L733
HLA class I histocompatibility antigen, A-3 alpha chainHLA-AQ5SRN53
HLA class I histocompatibility antigen, A-3 alpha chain (Fragment)HLA-AA0A140T9I03
HLA class II histocompatibility antigen, DR alpha chain (MHC cell surface glycoprotein)HLA-DRAQ301183
HMG domain-containing protein 4 (HMG box-containing protein 4) (High mobility group protein 2-like 1) (Protein HMGBCG)HMGXB4 HMG2L1 HMGBCGQ9UGU53
Homeobox protein cut-like 2 (Homeobox protein cux-2)CUX2 CUTL2 KIAA0293O145293
Homeobox protein Hox-A7 (Homeobox protein Hox 1.1) (Homeobox protein Hox-1A)HOXA7 HOX1AP312683
Homeobox protein Hox-C10 (Homeobox protein Hox-3I)HOXC10 HOX3IQ9NYD63
Homeobox protein Hox-C6 (Homeobox protein CP25) (Homeobox protein HHO.C8) (Homeobox protein Hox-3C)HOXC6 HOX3CP096303
Homeobox protein Nkx-3.1 (Homeobox protein NK-3 homolog A)NKX3-1 NKX3.1 NKX3AQ998013
Homologous-pairing protein 2 homolog (Nuclear receptor coactivator GT198) (PSMC3-interacting protein) (Proteasome 26S ATPase subunit 3-interacting protein) (Tat-binding protein 1-interacting protein) (TBP-1-interacting protein)PSMC3IP HOP2 TBPIPQ9P2W13
Host cell factor 1HCFC1A6NEM23
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