EVpedia provide top 100+ EV markers, selected according to their identification number.
Based on EV proteomes, we defined the identification number of protein A as the number of datasets which contain protein A.
Therefore, proteins with higher identification numbers were more conserved.

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Protein name Gene symbol UniProt accession Identification number
MICOS complex subunit MIC25 (Coiled-coil-helix cristae morphology protein 1) (Coiled-coil-helix-coiled-coil-helix domain-containing protein 6)CHCHD6 CHCM1 MIC25Q9BRQ63
Microfibril-associated glycoprotein 3MFAP3P550823
Microsomal glutathione S-transferase 1 (Fragment)MGST1F5H7F63
Microsomal glutathione S-transferase 2 (Microsomal GST-2) (EC 2.5.1.18) (Microsomal GST-II)MGST2 GST2Q997353
Microtubule-associated protein 1 light chain 3 beta, isoform CRA_f (Microtubule-associated proteins 1A/1B light chain 3B)MAP1LC3B hCG_32374H3BTL13
Microtubule-associated serine/threonine-protein kinase 4 (EC 2.7.11.1)MAST4 KIAA0303O150213
Minichromosome maintenance protein 4 (EC 3.6.1.15) (Fragment)MCM4A4FS093
Mis18-binding protein 1 (Kinetochore-associated protein KNL-2 homolog) (HsKNL-2) (P243)MIS18BP1 C14orf106 KIAA1903 KNL2 M18BP1Q6P0N03
Mitochondrial 2-oxoglutarate/malate carrier protein (Fragment)SLC25A11I3L1P83
Mitochondrial amidoxime-reducing component 1 (mARC1) (EC 1.-.-.-) (Molybdenum cofactor sulfurase C-terminal domain-containing protein 1) (MOSC domain-containing protein 1) (Moco sulfurase C-terminal domain-containing protein 1)MARC1 MOSC1Q5VT663
Mitochondrial fission regulator 1-likeMTFR1L FAM54B HYST1888 MSTP116Q9H0193
Mitochondrial folate transporter/carrier (Solute carrier family 25 member 32)SLC25A32 MFT MFTCQ9H2D13
Mitochondrial import receptor subunit TOM5 homologTOMM5 C9orf105 TOM5Q8N4H53
Mitochondrial import receptor subunit TOM7 homolog (Translocase of outer membrane 7 kDa subunit homolog)TOMM7 TOM7 TOMM07 AD-014Q9P0U13
Mitochondrial ribosome-associated GTPase 1 (GTP-binding protein 7) (Mitochondrial GTPase 1)MTG1 GTPBP7Q9BT173
Mitochondrial tRNA-specific 2-thiouridylase 1 (EC 2.8.1.14) (MTO2 homolog)TRMU MTU1 TRMT1O756483
Mitofusin-1 (EC 3.6.5.-) (Fzo homolog) (Transmembrane GTPase MFN1)MFN1Q8IWA43
Mitogen-activated protein kinase kinase 1, isoform CRA_d (cDNA FLJ58770, highly similar to Dual specificity mitogen-activated protein kinase kinase 1 (EC 2.7.12.2))MAP2K1 hCG_24510B4DFY53
Mitotic-spindle organizing protein 1 (Mitotic-spindle organizing protein associated with a ring of gamma-tubulin 1)MZT1 C13orf37 MOZART1Q08AG73
MLF2 protein (Myeloid leukemia factor 2) (Myeloid leukemia factor 2, isoform CRA_a) (cDNA, FLJ94652, Homo sapiens myeloid leukemia factor 2 (MLF2), mRNA)MLF2 hCG_25928Q5U0N13
Modulator of apoptosis 1 (MAP-1) (MAP1) (Paraneoplastic antigen Ma4)MOAP1 PNMA4Q96BY23
MON2 proteinMON2B7ZM733
Mov10, Moloney leukemia virus 10, homolog (Mouse), isoform CRA_a (Putative helicase MOV-10)MOV10 hCG_38463Q5JR043
mRNA for apolipoprotein E (apo E) (Fragment)0Q6LBZ13
MUC1 isoform J26 (Mucin-1)MUC1B6ECB53
MUC1 isoform M2MUC1A6ZID53
MUC1 isoform M8MUC1A6ZIE23
MUC1 isoform M9 (Mucin-1)MUC1A6ZIE33
MUC1 isoform T11MUC1A5YRV23
Mucin (Fragment)0Q9UMI83
Mucin short variant SV1MUC1Q7Z5453
Mucin short variant SV8MUC1Q7Z5413
Mucin-1 (MUC-1) (Breast carcinoma-associated antigen DF3) (Cancer antigen 15-3) (CA 15-3) (Carcinoma-associated mucin) (Episialin) (H23AG) (Krebs von den Lungen-6) (KL-6) (PEMT) (Peanut-reactive urinary mucin) (PUM) (Polymorphic epithelial mucin) (PEM) (Tumor-associated epithelial membrane antigen) (EMA) (Tumor-associated mucin) (CD antigen CD227) [Cleaved into: Mucin-1 subunit alpha (MUC1-NT) (MUC1-alpha); Mucin-1 subunit beta (MUC1-beta) (MUC1-CT)]MUC1 PUMQ7Z5473
Mucin-1 (MUC-1) (Breast carcinoma-associated antigen DF3) (Cancer antigen 15-3) (CA 15-3) (Carcinoma-associated mucin) (Episialin) (H23AG) (Krebs von den Lungen-6) (KL-6) (PEMT) (Peanut-reactive urinary mucin) (PUM) (Polymorphic epithelial mucin) (PEM) (Tumor-associated epithelial membrane antigen) (EMA) (Tumor-associated mucin) (CD antigen CD227) [Cleaved into: Mucin-1 subunit alpha (MUC1-NT) (MUC1-alpha); Mucin-1 subunit beta (MUC1-beta) (MUC1-CT)]MUC1 PUMB6ECA13
Mucin-16 (Fragment)MUC16M0QZZ93
Mucin-16 (Fragment)MUC16M0R2Y53
Mucin-7 (MUC-7) (Apo-MG2) (Salivary mucin-7)MUC7 MG2Q8TAX73
Mucin-like protein 1MUCL1F8VV133
Multidrug resistance protein 1 (EC 3.6.3.44) (ATP-binding cassette sub-family B member 1) (P-glycoprotein 1) (CD antigen CD243)ABCB1 MDR1 PGY1B5AK603
Multidrug resistance-associated protein 6 (ATP-binding cassette sub-family C member 6) (Anthracycline resistance-associated protein) (Multi-specific organic anion transporter E) (MOAT-E)ABCC6 ARA MRP6O952553
Multiple C2 and transmembrane domain-containing protein 2MCTP2Q6DN123
Multiple epidermal growth factor-like domains protein 6 (Multiple EGF-like domains protein 6) (Epidermal growth factor-like protein 3) (EGF-like protein 3)MEGF6 EGFL3 KIAA0815O750953
Multivesicular body subunit 12A (Fragment)MVB12AE9PLL03
Multivesicular body subunit 12A (Fragment)MVB12AE9PLZ83
Muscular LMNA-interacting protein (Muscular-enriched A-type laminin-interacting protein)MLIP C6orf142Q5VWP33
Myelin basic proteinMBPJ3QL643
MYH9 protein (Myosin-9)MYH9Q5BKV13
MYO1D protein (Fragment)MYO1DQ8N6183
MyoD family inhibitor domain-containing protein (I-mfa domain-containing protein) (hIC)MDFICQ9P1T73
Myosin-10 (Cellular myosin heavy chain, type B) (Myosin heavy chain 10) (Myosin heavy chain, non-muscle IIb) (Non-muscle myosin heavy chain B) (NMMHC-B) (Non-muscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB)MYH10Q9BWG03
Myosin-11 (Myosin heavy chain 11) (Myosin heavy chain, smooth muscle isoform) (SMMHC)MYH11 KIAA0866D2JYH73
Myosin-binding protein C, cardiac-type (Cardiac MyBP-C) (C-protein, cardiac muscle isoform)MYBPC3Q148963
Myosin-IIIb (EC 2.7.11.1)MYO3BQ8WXR43
Myosin-reactive immunoglobulin heavy chain variable region (Fragment)0Q9UL743
Myosin-reactive immunoglobulin heavy chain variable region (Fragment)0Q9UL923
Myosin-reactive immunoglobulin light chain variable region (Fragment)0Q9UL763
MyotrophinMTPNC9JL853
Myotubularin-related protein 14 (EC 3.1.3.-) (HCV NS5A-transactivated protein 4 splice variant A-binding protein 1) (NS5ATP4ABP1) (hJumpy)MTMR14 C3orf29Q8NCE23
Myotubularin-related protein 3 (EC 3.1.3.48) (FYVE domain-containing dual specificity protein phosphatase 1) (FYVE-DSP1) (Phosphatidylinositol-3,5-bisphosphate 3-phosphatase) (EC 3.1.3.95) (Phosphatidylinositol-3-phosphate phosphatase) (EC 3.1.3.64) (Zinc finger FYVE domain-containing protein 10)MTMR3 KIAA0371 ZFYVE10Q136153
N-acetylglucosamine-6-sulfatase (EC 3.1.6.14) (Glucosamine-6-sulfatase)0A8K6V63
N-acetyltransferase 14 (EC 2.3.1.-) (K562 cell-derived leucine-zipper-like protein 1)NAT14 KLP1Q8WUY83
N-acyl-phosphatidylethanolamine-hydrolyzing phospholipase D (N-acyl phosphatidylethanolamine phospholipase D) (NAPE-PLD) (NAPE-hydrolyzing phospholipase D) (EC 3.1.4.54)NAPEPLD C7orf18Q6IQ203
N-alpha-acetyltransferase 35, NatC auxiliary subunit (Embryonic growth-associated protein homolog) (Protein MAK10 homolog)NAA35 EGAP MAK10Q5VZE53
N-chimaerin (A-chimaerin) (Alpha-chimerin) (N-chimerin) (NC) (Rho GTPase-activating protein 2)CHN1 ARHGAP2 CHNP158823
NACHT domain- and WD repeat-containing protein 1NWD1Q149M93
NACHT, LRR and PYD domains-containing protein 13 (Nucleotide-binding oligomerization domain protein 14)NLRP13 NALP13 NOD14Q86W253
NACHT, LRR and PYD domains-containing protein 4 (Cancer/testis antigen 58) (CT58) (PAAD and NACHT-containing protein 2) (PAN2) (PYRIN and NACHT-containing protein 2) (PYRIN-containing APAF1-like protein 4) (PYPAF4) (Ribonuclease inhibitor 2)NLRP4 NALP4 PAN2 PYPAF4 RNH2Q96MN23
NACHT, LRR and PYD domains-containing protein 9 (Nucleotide-binding oligomerization domain protein 6) (PYRIN and NACHT-containing protein 12)NLRP9 NALP9 NOD6 PAN12Q7RTR03
NAD-dependent protein deacetylase sirtuin-1 (hSIRT1) (EC 3.5.1.-) (Regulatory protein SIR2 homolog 1) (SIR2-like protein 1) (hSIR2) [Cleaved into: SirtT1 75 kDa fragment (75SirT1)]SIRT1 SIR2L1Q96EB63
NAD-dependent protein deacetylase sirtuin-3, mitochondrial (hSIRT3) (EC 3.5.1.-) (Regulatory protein SIR2 homolog 3) (SIR2-like protein 3)SIRT3 SIR2L3Q9NTG73
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10NDUFB10H3BPJ93
NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial (Complex I-KFYI) (CI-KFYI) (NADH-ubiquinone oxidoreductase KFYI subunit)NDUFC1O436773
NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial (cDNA FLJ60586, highly similar to NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial (EC 1.6.5.3))NDUFS1B4DJ813
NADP-dependent malic enzyme, mitochondrial (NADP-ME) (EC 1.1.1.40) (Malic enzyme 3)ME3Q167983
NADPH oxidase 1 (NOX-1) (EC 1.-.-.-) (Mitogenic oxidase 1) (MOX-1) (NADH/NADPH mitogenic oxidase subunit P65-MOX) (NOH-1)NOX1 MOX1 NOH1Q9Y5S83
NDRG family member 3, isoform CRA_c (Protein NDRG3)NDRG3 hCG_1785125Q5TH303
NebulinNEBF8WCL53
Neprilysin (Fragment)MMEC9J9X73
Netrin receptor UNC5A (Protein unc-5 homolog 1) (Protein unc-5 homolog A)UNC5A KIAA1976 UNC5H1Q6ZN443
Neuralized-like protein 4NEURL4 KIAA1787Q96JN83
Neurexin-3-beta (Neurexin III-beta) [Cleaved into: Neurexin-3-beta, soluble form; Neurexin-3-beta, C-terminal fragment (NRXN3-CTF)]NRXN3 KIAA0743Q9HDB53
Neurobeachin-like protein 2 (Fragment)NBEAL2H0Y7643
Neuroendocrine protein 7B2 (Pituitary polypeptide) (Secretogranin V) (Secretogranin-5) (Secretory granule endocrine protein I) [Cleaved into: N-terminal peptide; C-terminal peptide]SCG5 SGNE1P054083
Neurofilament medium polypeptideNEFME7ESP93
Neurogenic differentiation factor 1 (NeuroD) (NeuroD1) (Class A basic helix-loop-helix protein 3) (bHLHa3)NEUROD1 BHLHA3 NEURODQ135623
Neurogenic locus notch homolog protein 4 (Notch 4) (hNotch4) [Cleaved into: Notch 4 extracellular truncation; Notch 4 intracellular domain]NOTCH4 INT3Q994663
Neuroligin-1NLGN1 KIAA1070Q8N2Q73
Neuron navigator 3 (Pore membrane and/or filament-interacting-like protein 1) (Steerin-3) (Unc-53 homolog 3) (unc53H3)NAV3 KIAA0938 POMFIL1 STEERIN3Q8IVL03
Neuronal PAS domain-containing protein 3 (Fragment)NPAS3F8VS423
Neuronal vesicle trafficking-associated protein 2 (Neuron-specific protein family member 2) (Protein p19) (Hmp19)NSG2 CALY3Q9Y3283
Neuropeptide Y receptor type 1 (NPY1-R)NPY1R NPYR NPYY1P259293
Neurotrophin receptor-interacting factor homolog (Zinc finger protein 274) (Zinc finger protein HFB101) (Zinc finger protein with KRAB and SCAN domains 19) (Zinc finger protein zfp2) (Zf2)ZNF274 ZKSCAN19 SP2114Q96GC63
Neutral alpha-glucosidase AB (Fragment)GANABE9PNH13
Neutral amino acid transporter B(0) (ATB(0)) (Baboon M7 virus receptor) (RD114/simian type D retrovirus receptor) (Sodium-dependent neutral amino acid transporter type 2) (Solute carrier family 1 member 5)SLC1A5 ASCT2 M7V1 RDR RDRCB4DWS43
Next to BRCA1 gene 1 protein (cDNA FLJ55359, highly similar to Next to BRCA1 gene 1 protein)NBR1B7Z5R63
NF-kappa-B inhibitor-interacting Ras-like protein 1 (I-kappa-B-interacting Ras-like protein 1) (Kappa B-Ras protein 1) (KappaB-Ras1)NKIRAS1 KBRAS1Q9NYS03
NF90b0F4ZW653
NHP2 non-histone chromosome protein 2-like 1 (S. cerevisiae) (NHP2 non-histone chromosome protein 2-like 1 (S. cerevisiae), isoform CRA_a) (NHP2L1 protein) (cDNA, FLJ92061, Homo sapiens NHP2 non-histone chromosome protein 2-like 1 (S.cerevisiae) (NHP2L1), mRNA)NHP2L1 hCG_41538Q6FHM63
Nibrin (Cell cycle regulatory protein p95) (Nijmegen breakage syndrome protein 1)NBN NBS NBS1 P95O609343
Nicotinate phosphoribosyltransferase (Nicotinate phosphoribosyltransferase domain containing 1, isoform CRA_e)NAPRT NAPRT1 hCG_32062C9J8U23
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