EVpedia provide top 100+ EV markers, selected according to their identification number.
Based on EV proteomes, we defined the identification number of protein A as the number of datasets which contain protein A.
Therefore, proteins with higher identification numbers were more conserved.

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Protein name Gene symbol UniProt accession Identification number
Ninein-like proteinNINL KIAA0980 NLPQ9Y2I63
Nitric oxide synthase, brain (EC 1.14.13.39) (Constitutive NOS) (NC-NOS) (NOS type I) (Neuronal NOS) (N-NOS) (nNOS) (Peptidyl-cysteine S-nitrosylase NOS1) (bNOS)NOS1P294753
Nitric oxide synthase, endothelial (EC 1.14.13.39) (Constitutive NOS) (cNOS) (EC-NOS) (Endothelial NOS) (eNOS) (NOS type III) (NOSIII)NOS3P294743
NKG2D ligand 1 (N2DL-1) (NKG2DL1) (ALCAN-beta) (Retinoic acid early transcript 1I) (UL16-binding protein 1)ULBP1 N2DL1 RAET1IQ9BZM63
NMDA receptor regulated 1-like (NMDA receptor regulated 1-like, isoform CRA_c) (cDNA FLJ77538, highly similar to Homo sapiens NMDA receptor regulated 1-like (NARG1L), transcript variant 1, mRNA)NARG1L hCG_2020106A4FU513
NNMT protein (Nicotinamide N-methyltransferase) (Nicotinamide N-methyltransferase, isoform CRA_a)NNMT hCG_39357Q6FH493
Non-homologous end-joining factor 1 (Protein cernunnos) (XRCC4-like factor)NHEJ1 XLFQ9H9Q43
Non-SMC condensin I complex, subunit GNCAPGQ6NUR13
Normal mucosa of esophagus-specific gene 1 protein (Protein FOAP-11)NMES1 C15orf48Q9C0023
NUCB1 protein0Q96BA43
Nuclear pore complex protein Nup155NUP155E9PF103
Nuclear respiratory factor 1 (NRF-1) (Alpha palindromic-binding protein) (Alpha-pal)NRF1Q166563
Nuclear speckle splicing regulatory protein 1 (Coiled-coil domain-containing protein 55) (Nuclear speckle-related protein 70) (NSrp70)NSRP1 CCDC55 NSRP70Q9H0G53
Nuclear transport factor 2 (Fragment)NUTF2H3BRV93
Nucleolar protein of 40 kDa (pNO40) (Pnn-interacting nucleolar protein) (Putative S1 RNA-binding domain protein) (PS1D protein) (Zinc finger CCHC domain-containing protein 17)ZCCHC17 PS1D HSPC243 HSPC251 LDC4Q9NP643
Nucleophosmin (Fragment)NPM1E5RGW43
Nucleoside diphosphate-linked moiety X motif 19 (Nudix motif 19) (EC 3.6.1.-)NUDT19A8MXV43
Nucleosome assembly protein 1-like 1 (Fragment)NAP1L1H0YHC33
Nucleosome assembly protein 1-like 4 (Fragment)NAP1L4E9PKT83
Obg-like ATPase 1 (DNA damage-regulated overexpressed in cancer 45) (DOC45) (GTP-binding protein 9)OLA1 GTPBP9 PRO2455 PTD004D7EHM23
ObscurinOBSCNA6NGQ33
Olfactory receptor 2G2 (Olfactory receptor OR1-32)OR2G2Q8NGZ53
Olfactory receptor 51E2 (HPRAJ) (Olfactory receptor OR11-16) (Prostate-specific G-protein coupled receptor)OR51E2 PSGRQ9H2553
One cut domain family member 3 (One cut homeobox 3) (Transcription factor ONECUT-3) (OC-3)ONECUT3O604223
Opioid growth factor receptor-like protein 1OGFRL1Q5TC843
Ornithine decarboxylase (ODC) (EC 4.1.1.17)ODC1P119263
Ovarian/Breast septin epsilon (Fragment)Ov/Br septinQ96QF23
OX-2 membrane glycoprotein (Fragment)CD200U3KQG53
Oxysterol-binding protein 2 (Oxysterol-binding protein-related protein 4) (ORP-4) (OSBP-related protein 4)OSBP2 KIAA1664 ORP4 OSBPL4Q969R23
P2X purinoceptor 1 (P2X1) (ATP receptor) (Purinergic receptor)P2RX1 P2X1P515753
P2X purinoceptor 5 (P2X5) (ATP receptor) (Purinergic receptor)P2RX5 P2X5Q930863
p400O003773
PAB-dependent poly(A)-specific ribonuclease subunit PAN2 (hPan2) (EC 3.1.13.4) (Inactive ubiquitin carboxyl-terminal hydrolase 52) (PAB1P-dependent poly(A)-nuclease) (PAN deadenylation complex catalytic subunit 2)PAN2 KIAA0710 USP52Q504Q33
Palladin (Fragment)PALLDH0YA053
Palmitoyltransferase ZDHHC13 (EC 2.3.1.225) (Huntingtin-interacting protein 14-related protein) (HIP14-related protein) (Huntingtin-interacting protein HIP3RP) (Putative MAPK-activating protein PM03) (Putative NF-kappa-B-activating protein 209) (Zinc finger DHHC domain-containing protein 13) (DHHC-13)ZDHHC13 HIP14L HIP3RPQ8IUH43
Palmitoyltransferase ZDHHC2 (EC 2.3.1.225) (Reduced expression associated with metastasis protein) (Ream) (Reduced expression in cancer protein) (Rec) (Zinc finger DHHC domain-containing protein 2) (DHHC-2) (Zinc finger protein 372)ZDHHC2 REAM REC ZNF372Q9UIJ53
Palmitoyltransferase ZDHHC9 (EC 2.3.1.225) (Zinc finger DHHC domain-containing protein 9) (DHHC-9) (DHHC9) (Zinc finger protein 379) (Zinc finger protein 380)ZDHHC9 CXorf11 ZDHHC10 ZNF379 ZNF380 CGI-89 UNQ261/PRO298Q9Y3973
Pantothenate kinase 1 (hPanK) (hPanK1) (EC 2.7.1.33) (Pantothenic acid kinase 1)PANK1 PANKQ8TE043
PAPSS1 protein (Fragment)PAPSS1Q05BW93
Paraplegin (EC 3.4.24.-) (Spastic paraplegia 7 protein)SPG7 CAR PGNQ9UQ903
Part of human delta-globin (amino acids 105 to 122) (Fragment)0Q9UE583
PAX3- and PAX7-binding protein 1 (GC-rich sequence DNA-binding factor 1)PAXBP1 C21orf66 GCFC GCFC1Q9Y5B63
PDZ domain-containing protein 7PDZD7 PDZK7Q9H5P43
Pecanex-like protein 4 (Hepatitis C virus F protein-binding protein 2) (HCV F protein-binding protein 2) (Pecanex homolog protein 4)PCNX4 C14orf135 FBP2 PCNXL4Q63HM23
Pepsin A-5 (EC 3.4.23.1) (Pepsinogen-5)PGA5P0DJD93
Peptidyl-prolyl cis-trans isomerase (PPIase) (EC 5.2.1.8)PPIAC9J5S73
Peptidyl-prolyl cis-trans isomerase A (PPIase A) (EC 5.2.1.8) (Cyclophilin A) (Cyclosporin A-binding protein) (Rotamase A) [Cleaved into: Peptidyl-prolyl cis-trans isomerase A, N-terminally processed]PPIA CYPAQ567Q03
Peptidyl-prolyl cis-trans isomerase A-like 4G (PPIase A-like 4G) (EC 5.2.1.8) (Peptidylprolyl cis-trans isomerase A-like 4)PPIAL4GA2BFH13
Peptidyl-prolyl cis-trans isomerase-like 2 (PPIase) (EC 2.3.2.27) (EC 5.2.1.8) (CYC4) (Cyclophilin-60) (Cyclophilin-like protein Cyp-60) (Cyp60) (hCyP-60) (RING-type E3 ubiquitin transferase isomerase-like 2) (Rotamase PPIL2)PPIL2Q133563
PeriostinPOSTNB1ALD93
Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIMS-binding protein 1) (RIM-BP1) (TSPO-associated protein 1)TSPOAP1 BZRAP1 KIAA0612 RBP1 RIMBP1O951533
Periphilin-1 (CDC7 expression repressor) (CR) (Gastric cancer antigen Ga50)PPHLN1 HSPC206 HSPC232Q8NEY83
Perlecan proteoglycan 2 (Fragment)HSPG2B6EU513
Peroxiredoxin 3 isoform a variant (Fragment)0Q53HC23
Peroxiredoxin-5, mitochondrial (EC 1.11.1.15) (Alu corepressor 1) (Antioxidant enzyme B166) (AOEB166) (Liver tissue 2D-page spot 71B) (PLP) (Peroxiredoxin V) (Prx-V) (Peroxisomal antioxidant enzyme) (TPx type VI) (Thioredoxin peroxidase PMP20) (Thioredoxin reductase)PRDX5 ACR1 SBBI10A6NG063
Peroxisomal carnitine O-octanoyltransferase (COT) (EC 2.3.1.137)CROT COTQ9UKG93
Peroxisomal membrane protein PEX16 (Peroxin-16) (Peroxisomal biogenesis factor 16)PEX16Q9Y5Y53
Peroxisomal membrane protein PMP34 (34 kDa peroxisomal membrane protein) (Solute carrier family 25 member 17)SLC25A17 PMP34O438083
Peroxisomal multifunctional enzyme type 2HSD17B4E7ER273
Peroxisome proliferator-activated receptor gamma coactivator-related protein 1 (PGC-1-related coactivator) (PRC)PPRC1 KIAA0595Q5VV673
PH domain leucine-rich repeat-containing protein phosphatase 1 (EC 3.1.3.16) (Pleckstrin homology domain-containing family E member 1) (PH domain-containing family E member 1) (Suprachiasmatic nucleus circadian oscillatory protein) (hSCOP)PHLPP1 KIAA0606 PHLPP PLEKHE1 SCOPO603463
Phenylalanine--tRNA ligase alpha subunitFARSAK7ER003
Phenylalanine--tRNA ligase alpha subunit (Fragment)FARSAK7EPH23
Phosphate-regulating neutral endopeptidase (EC 3.4.24.-) (Metalloendopeptidase homolog PEX) (Vitamin D-resistant hypophosphatemic rickets protein) (X-linked hypophosphatemia protein) (HYP)PHEX PEXP785623
Phosphatidate phosphatase LPIN1 (EC 3.1.3.4) (Lipin-1)LPIN1 KIAA0188Q146933
Phosphatidate phosphatase LPIN3 (EC 3.1.3.4) (Lipin-3) (Lipin-3-like)LPIN3 LIPN3LQ9BQK83
Phosphatidylinositol transfer protein beta isoformPITPNBA0A0A0MSW43
Phosphoacetylglucosamine mutase (PAGM) (EC 5.4.2.3) (Acetylglucosamine phosphomutase) (N-acetylglucosamine-phosphate mutase) (Phosphoglucomutase-3) (PGM 3)PGM3 AGM1E9PF863
Phosphoethanolamine/phosphocholine phosphatase (EC 3.1.3.75)PHOSPHO1Q8TCT13
Phosphoinositide phospholipase C (EC 3.1.4.11)0B3KXR53
Phosphoinositide phospholipase C (EC 3.1.4.11)PLCD3 hCG_28072D3DX633
Phospholipase B1, membrane-associated (Phospholipase B) (hPLB) (Phospholipase B/lipase) (PLB/LIP) [Includes: Phospholipase A2 (EC 3.1.1.4); Lysophospholipase (EC 3.1.1.5)]PLB1 PLBQ6P1J63
Phospholipid phosphatase 3 (EC 3.1.3.4) (Lipid phosphate phosphohydrolase 3) (PAP2-beta) (Phosphatidate phosphohydrolase type 2b) (Phosphatidic acid phosphatase 2b) (PAP-2b) (PAP2b) (Vascular endothelial growth factor and type I collagen-inducible protein) (VCIP)PLPP3 LPP3 PPAP2BQ5U0F73
Phospholipid scramblase0B3KP673
Phospholipid scramblaseTMEM256-PLSCR3I3L3X53
Phospholipid scramblase (Fragment)PLSCR3I3L4F53
Phospholipid transfer protein C2CD2L (C2 domain-containing protein 2-like) (Transmembrane protein 24)C2CD2L KIAA0285 TMEM24 DLNB23O145233
Phospholipid-transporting ATPase IK (EC 3.6.3.1) (ATPase class I type 8B member 3)ATP8B3 ATP1K FOS37502_2O604233
Phosphopantothenate--cysteine ligasePPCSQ5VVM33
Phosphopantothenoylcysteine decarboxylase (PPC-DC) (EC 4.1.1.36) (CoaC)PPCDC COAC MDS018 UNQ9365/PRO34154Q96CD23
Phosphoribosyl pyrophosphate amidotransferase proprotein variant (Fragment)0Q53H223
Phosphorylated adapter RNA export protein (RNA U small nuclear RNA export adapter protein)PHAX RNUXAQ9H8143
Phosphotyrosine independent ligand p62B for the Lck SH2 domain B-cell isoform (Fragment)0Q135023
PHP14 proteinPHP14Q6FIE53
PI-PLC X domain-containing protein 2PLCXD2Q0VAA53
Pigment epithelium-derived factor (PEDF) (Cell proliferation-inducing gene 35 protein) (EPC-1) (Serpin F1)SERPINF1 PEDF PIG35F1T0923
PIK3R2 proteinPIK3R2Q05BV63
PILR alpha-associated neural protein (PILR-associating neural protein) (Paired immunoglobin-like type 2 receptor-associating neural protein)PIANP C12orf53 PANP UNQ828/PRO1755Q8IYJ03
PIN2/TERF1-interacting telomerase inhibitor 1 (Liver-related putative tumor suppressor) (Pin2-interacting protein X1) (Protein 67-11-3) (TRF1-interacting protein 1)PINX1 LPTL LPTSQ96BK53
Piwi-like protein 2 (EC 3.1.26.-) (Cancer/testis antigen 80) (CT80)PIWIL2 HILIQ8TC593
Piwi-like protein 4PIWIL4 HIWI2 PIWIQ7Z3Z43
Plakophilin-2PKP2B8QGS63
Plastin-3 (T-plastin)PLS3A8K5793
Platelet endothelial cell adhesion moleculePECAM1A0A075B7383
Platelet-activating factor acetylhydrolase IB subunit gamma (Fragment)PAFAH1B3M0R3893
Pleckstrin homology domain-containing family A member 3 (PH domain-containing family A member 3) (Phosphatidylinositol-four-phosphate adapter protein 1) (FAPP-1) (Phosphoinositol 4-phosphate adapter protein 1)PLEKHA3 FAPP1Q9HB203
Pleckstrin homology domain-containing family N member 1 (PH domain-containing family N member 1)PLEKHN1Q494U13
Plexin domain-containing protein 1 (Tumor endothelial marker 3) (Tumor endothelial marker 7)PLXDC1 TEM3 TEM7Q8IUK53
PNMA-like protein 1PNMAL1Q86V593
Pol protein0Q86UH83
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