EVpedia provide top 100+ EV markers, selected according to their identification number.
Based on EV proteomes, we defined the identification number of protein A as the number of datasets which contain protein A.
Therefore, proteins with higher identification numbers were more conserved.

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Protein name Gene symbol UniProt accession Identification number
Sphingosine 1-phosphate receptor 1 (S1P receptor 1) (S1P1) (Endothelial differentiation G-protein coupled receptor 1) (Sphingosine 1-phosphate receptor Edg-1) (S1P receptor Edg-1) (CD antigen CD363)S1PR1 CHEDG1 EDG1P214533
Sphingosine 1-phosphate receptor 4 (S1P receptor 4) (S1P4) (Endothelial differentiation G-protein coupled receptor 6) (Sphingosine 1-phosphate receptor Edg-6) (S1P receptor Edg-6)S1PR4 EDG6O959773
Spindle assembly abnormal protein 6 homolog (HsSAS-6)SASS6 SAS6Q6UVJ03
SPINT2 protein (Fragment)SPINT2Q6LEU83
Spliceosome RNA helicase DDX39BDDX39BQ5STU33
Splicing factor 3B subunit 6 (Pre-mRNA branch site protein p14) (SF3b 14 kDa subunit) (SF3B14a) (Spliceosome-associated protein, 14-kDa) (Splicing factor 3b, subunit 6, 14kDa)SF3B6 SAP14 SF3B14 SF3B14A CGI-110 HSPC175 HT006Q53TM13
Splicing factor, arginine/serine-rich 4 variant (Fragment)0Q59EF53
Squalene monooxygenase (EC 1.14.14.17) (Squalene epoxidase) (SE)SQLE ERG1Q145343
Src kinase-associated phosphoprotein 1 (Src family-associated phosphoprotein 1) (Src kinase-associated phosphoprotein of 55 kDa) (SKAP-55) (pp55)SKAP1 SCAP1 SKAP55Q86WV13
Src-like-adapter 2 (Modulator of antigen receptor signaling) (MARS) (Src-like adapter protein 2) (SLAP-2)SLA2 C20orf156 SLAP2Q9H6Q33
SRSF protein kinase 1 (EC 2.7.11.1) (SFRS protein kinase 1) (Serine/arginine-rich protein-specific kinase 1) (SR-protein-specific kinase 1)SRPK1B4DS613
SRSF protein kinase 1 (Fragment)SRPK1H3BLV93
StAR-related lipid transfer protein 8 (Deleted in liver cancer 3 protein) (DLC-3) (START domain-containing protein 8) (StARD8) (START-GAP3)STARD8 DLC3 KIAA0189Q925023
Stathmin (Fragment)STMN1A2A2D03
Sterol regulatory element-binding protein 1 (SREBP-1) (Class D basic helix-loop-helix protein 1) (bHLHd1) (Sterol regulatory element-binding transcription factor 1) [Cleaved into: Processed sterol regulatory element-binding protein 1]SREBF1 BHLHD1 SREBP1P369563
Stomatin-like protein 2, mitochondrial (SLP-2) (EPB72-like protein 2) (Paraprotein target 7) (Paratarg-7)STOML2 SLP2 HSPC108B4E1K73
Stress-induced-phosphoprotein 1 (STI1) (Hsc70/Hsp90-organizing protein) (Hop) (Renal carcinoma antigen NY-REN-11) (Transformation-sensitive protein IEF SSP 3521)STIP1Q3ZCU93
Structural maintenance of chromosomes protein0A8K9843
Structural maintenance of chromosomes protein0B0AZQ43
Structural maintenance of chromosomes proteinSMC3Q86VX43
Structural maintenance of chromosomes protein0B3KMB13
Structure-specific endonuclease subunit SLX4 (BTB/POZ domain-containing protein 12)SLX4 BTBD12 KIAA1784 KIAA1987Q8IY923
Sugar phosphate exchanger 3 (Solute carrier family 37 member 3)SLC37A3 SPX3Q8NCC53
Sulfotransferase (EC 2.8.2.-)0B3KT143
Sulfotransferase 1A2 (ST1A2) (EC 2.8.2.1) (Aryl sulfotransferase 2) (Phenol sulfotransferase 2) (Phenol-sulfating phenol sulfotransferase 2) (P-PST 2)SULT1A2 STP2P502263
Surfeit 4 (Surfeit locus protein 4)SURF4 RP11-244N20.4-004Q5T8U53
Synapse-associated protein 102 variant (Fragment)0Q59FY13
Synaptogyrin-1 (cDNA FLJ52856, highly similar to Synaptogyrin-1)SYNGR1B5MCD73
Synaptogyrin-2SYNGR2K7ELD93
Synaptonemal complex protein 2 (Fragment)SYCP2A2A3413
Synaptophysin-like protein 1 (Pantophysin)SYPL1 SYPLA4D0R23
Synaptosomal-associated protein 23SNAP23H3BNG63
Syncoilin (Syncoilin intermediate filament 1) (Syncoilin-1)SYNC SYNC1Q9H7C43
SyntaphilinSNPH KIAA0374O150793
Syntaxin-3 (Fragment)STX3A0A0C4DGE43
T-cell antigen CD7 (GP40) (T-cell leukemia antigen) (T-cell surface antigen Leu-9) (TP41) (CD antigen CD7)CD7P095643
T-cell receptor-associated transmembrane adapter 1 (T-cell receptor-interacting molecule) (TRIM) (pp29/30)TRAT1 TCRIM HSPC062Q6PIZ93
T-cell surface glycoprotein CD3 gamma chain (T-cell receptor T3 gamma chain) (CD antigen CD3g)CD3G T3GP096933
T-cell surface glycoprotein CD8 alpha chain (T-lymphocyte differentiation antigen T8/Leu-2) (CD antigen CD8a)CD8A MALP017323
T-cell-specific surface glycoprotein CD28 (TP44) (CD antigen CD28)CD28P107473
T-cluster binding protein (TIA1 cytotoxic granule-associated RNA binding protein-like 1, isoform CRA_a)TIAL1 hCG_40603O151873
T-complex protein 1 subunit alphaTCP1E7ERF23
T-complex protein 1 subunit alpha (Fragment)TCP1F5H7Y13
T-complex protein 1 subunit zeta-2 (TCP-1-zeta-2) (CCT-zeta-2) (CCT-zeta-like) (TCP-1-zeta-like) (Testis-specific Tcp20) (Testis-specific protein TSA303)CCT6BB4DX203
T-complex protein 11-like protein 1TCP11L1Q9NUJ33
Target of Myb protein 1 (Fragment)TOM1B0QY013
Tau-tubulin kinase 2 (EC 2.7.11.1)TTBK2 KIAA0847Q6IQ553
TBC1 domain family member 25TBC1D25 OATL1Q3MII63
TBL3 protein (Fragment)TBL3A0JLS53
Tektin-5TEKT5Q96M293
Telomerase protein component 1TEP1G3V4703
Telomerase-binding protein EST1A (EC 3.1.-.-) (EST1-like protein A) (Ever shorter telomeres 1A) (Smg-6 homolog) (Telomerase subunit EST1A) (hSmg5/7a)SMG6 C17orf31 EST1A KIAA0732Q86US83
Tenascin-R (TN-R) (Janusin) (Restrictin)TNRQ927523
Testicular haploid expressed gene protein (Cancer/testis antigen 56) (CT56)THEGQ9P2T03
Testis-expressed protein 101 (Cell surface receptor NYD-SP8) (Scleroderma-associated autoantigen) (Spermatogenesis-related gene protein)TEX101 SGRG UNQ867/PRO1884Q9BY143
Testis-expressed protein 15 (Cancer/testis antigen 42) (CT42)TEX15Q9BXT53
Testis-expressed protein 2 (Transmembrane protein 96)TEX2 KIAA1738 TMEM96Q8IWB93
Testis-specific serine kinase substrate (Testis-specific kinase substrate) (STK22 substrate 1)TSKS STK22S1 TSKS1Q9UJT23
Testis-specific Y-encoded-like protein 2 (TSPY-like protein 2) (Cell division autoantigen 1) (Cutaneous T-cell lymphoma-associated antigen se20-4) (CTCL-associated antigen se20-4) (Differentially-expressed nucleolar TGF-beta1 target protein) (Nuclear protein of 79 kDa) (NP79)TSPYL2 CDA1 DENTT TSPX HRIHFB2216Q9H2G43
Testis-specific Y-encoded-like protein 5 (TSPY-like protein 5)TSPYL5 KIAA1750Q86VY43
TetraspaninBTCC-1Q56CY13
TetraspaninTSPAN14H7BXY63
Tetraspanin (Fragment)TM4SF9Q6FHC53
Tetraspanin (Fragment)CD151E9PRJ33
Tetraspanin-15 (Fragment)TSPAN15H7C2853
Tetraspanin-3TSPAN3H0YKJ93
Tetratricopeptide repeat domain 7A, isoform CRA_a (Tetratricopeptide repeat protein 7A)TTC7A hCG_17034G5E9G43
Tetratricopeptide repeat protein 13 (TPR repeat protein 13)TTC13 PSEC0076Q8NBP03
Tetratricopeptide repeat protein 17 (TPR repeat protein 17)TTC17Q96AE73
Tetratricopeptide repeat protein 30A (TPR repeat protein 30A)TTC30AQ86WT13
Tetratricopeptide repeat protein 39B (TPR repeat protein 39B)TTC39B C9orf52Q5VTQ03
Tetratricopeptide repeat protein 9A (TPR repeat protein 9A)TTC9 KIAA0227 TTC9AQ926233
TF protein (Fragment)TFA0PJA63
THBS1 protein (Fragment)THBS1A0PJG03
Thimet oligopeptidaseTHOP1K7EP463
Thioredoxin reductase 1, cytoplasmic (Fragment)TXNRD1E9PQI33
Thioredoxin reductase 1, cytoplasmic (Fragment)TXNRD1E9PKD33
Thioredoxin-dependent peroxide reductase, mitochondrial (EC 1.11.1.15) (Antioxidant protein 1) (AOP-1) (HBC189) (Peroxiredoxin III) (Prx-III) (Peroxiredoxin-3) (Protein MER5 homolog)PRDX3 AOP1E9PH293
Thioredoxin-like protein 4B (Dim1-like protein)TXNL4B DIM2 DLPQ9NX013
Three prime repair exonuclease 2 (EC 3.1.11.2) (3'-5' exonuclease TREX2)TREX2Q9BQ503
Thy-1 membrane glycoprotein (Fragment)THY1E9PIM63
Thyroid receptor-interacting protein 11 (TR-interacting protein 11) (TRIP-11) (Clonal evolution-related gene on chromosome 14 protein) (Golgi-associated microtubule-binding protein 210) (GMAP-210) (Trip230)TRIP11 CEV14B2RUT23
Thyrotropin receptor (Thyroid-stimulating hormone receptor) (TSH-R)TSHR LGR3P164733
Tight junction-associated protein 1 (Protein incorporated later into tight junctions) (Tight junction protein 4)TJAP1 PILT TJP4Q5JTD03
Tissue factor (TF)0B2R6M53
Tissue-type plasminogen activator (cDNA FLJ59358, highly similar to Tissue-type plasminogen activator (EC 3.4.21.68))PLATB4DNJ13
Tissue-type plasminogen activator (EC 3.4.21.68)0B4DRD33
Tissue-type plasminogen activator (Fragment)PLATE5RGA13
TitinTTNA0A0A0MRA33
Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS-40.14)TTNK7ENY13
TLR4 interactor with leucine rich repeats (Leucine-rich repeat-containing protein KIAA0644)TRIL KIAA0644Q7L0X03
TNF receptor-associated factor 6 (EC 2.3.2.27) (E3 ubiquitin-protein ligase TRAF6) (Interleukin-1 signal transducer) (RING finger protein 85) (RING-type E3 ubiquitin transferase TRAF6)TRAF6 RNF85Q9Y4K33
TNF receptor-associated factor 7, isoform CRA_cTRAF7 hCG_41031D3DU863
TNF receptor-associated protein 1 variant (Fragment)0Q59EK63
TNFRSF10B protein (Tumor necrosis factor receptor superfamily, member 10b) (Tumor necrosis factor receptor superfamily, member 10b, isoform CRA_a) (cDNA FLJ76289, highly similar to Homo sapiens tumor necrosis factor receptor superfamily, member 10b (TNFRSF10B), transcript variant 1, mRNA)TNFRSF10B hCG_1645072Q6FH583
Toll-interacting proteinTOLLIPF2Z2Y83
TOLLIP protein (Toll interacting protein) (Toll interacting protein, isoform CRA_a) (cDNA, FLJ96670, Homo sapiens toll interacting protein (TOLLIP), mRNA)TOLLIP hCG_40380Q6FIE93
Tomoregulin-1 (TR-1) (H7365) (Transmembrane protein with EGF-like and one follistatin-like domain)TMEFF1 C9orf2Q8IYR63
TOP1 protein (Fragment)TOP1Q6NWZ53
TPT1-like protein0Q56UQ53
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