EVpedia provide top 100+ EV markers, selected according to their identification number.
Based on EV proteomes, we defined the identification number of protein A as the number of datasets which contain protein A.
Therefore, proteins with higher identification numbers were more conserved.

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Protein name Gene symbol UniProt accession Identification number
Zinc finger protein 649ZNF649Q9BS313
Zinc finger protein 671ZNF671Q8TAW33
Zinc finger protein 768ZNF768Q9H5H43
Zinc finger protein 792ZNF792Q3KQV33
Zinc finger protein 804AZNF804A C2orf10Q7Z5703
Zinc finger protein basonuclin-1BNC1F5GY043
Zinc finger protein-like 1 (Zinc finger protein MCG4)ZFPL1O951593
Zinc transporter ZIP6 (Fragment)SLC39A6K7EQ913
Zona pellucida sperm-binding protein 2 (Zona pellucida glycoprotein 2) (Zp-2) (Zona pellucida protein A) [Cleaved into: Processed zona pellucida sperm-binding protein 2]ZP2 ZPAQ059963
Zymogen granule protein 16 homolog BZG16BA0A0C4DGN43
[F-actin]-methionine sulfoxide oxidase MICAL3 (Fragment)MICAL3J3KSK63
(clone XP6G6B) mRNA, partial EST (Fragment)0Q158992
1,4-alpha-glucan-branching enzyme (EC 2.4.1.18) (Brancher enzyme) (Glycogen-branching enzyme)GBE1B3KWV32
1,5-anhydro-D-fructose reductase (Aldo-keto reductase family 1, member C-like 2, isoform CRA_c)AKR1E2 AKR1CL2 hCG_22604G3V1C12
1-acylglycerol-3-phosphate O-acyltransferase ABHD5 (EC 2.3.1.51) (Abhydrolase domain-containing protein 5) (Lipid droplet-binding protein CGI-58)ABHD5 NCIE2 CGI-58Q8WTS12
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 (EC 3.1.4.11) (Phosphoinositide phospholipase C-beta-4) (Phospholipase C-beta-4) (PLC-beta-4)PLCB4Q9BQW82
116 kDa U5 small nuclear ribonucleoprotein component (Elongation factor Tu GTP-binding domain-containing protein 2) (SNU114 homolog) (hSNU114) (U5 snRNP-specific protein, 116 kDa) (U5-116 kDa)EFTUD2 KIAA0031 SNRP116Q9BUR02
116 kDa U5 small nuclear ribonucleoprotein component (Fragment)EFTUD2K7EJ742
14-3-3 protein beta/alpha (Fragment)YWHABQ4VY192
14-3-3 protein epsilon (14-3-3E)YWHAEP293602
14-3-3 protein gamma (Protein kinase C inhibitor protein 1) (KCIP-1) [Cleaved into: 14-3-3 protein gamma, N-terminally processed]YWHAGO704572
14-3-3 protein protein ( cytosolic phospholipase A2protein ) (Fragment)14-3-3 protein cytosolic phospholipase A2Q6LD622
14-3-3 protein zeta/delta (Fragment)YWHAZE7EVZ22
2'-5'-oligoadenylate synthase 1OAS1F8VXY32
2,4-dienoyl-CoA reductase, mitochondrial (EC 1.3.1.34) (2,4-dienoyl-CoA reductase [NADPH]) (4-enoyl-CoA reductase [NADPH]) (Short chain dehydrogenase/reductase family 18C member 1)DECR1 DECR SDR18C1B7Z6B82
2-(3-amino-3-carboxypropyl)histidine synthase subunit 2 (EC 2.5.1.108) (Diphthamide biosynthesis protein 2) (Diphtheria toxin resistance protein 2) (S-adenosyl-L-methionine:L-histidine 3-amino-3-carboxypropyltransferase 2)DPH2 DPH2L2Q9BQC32
2-deoxyribose-5-phosphate aldolase homolog (C. elegans), isoform CRA_a (Deoxyribose-phosphate aldolase)DERA hCG_25164G3V1582
2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial (Fragment)COQ5F8VVD52
2-oxoglutarate dehydrogenase-like, mitochondrial (EC 1.2.4.-) (2-oxoglutarate dehydrogenase complex component E1-like) (OGDC-E1-like) (Alpha-ketoglutarate dehydrogenase-like)OGDHL KIAA1290Q9ULD02
2-oxoglutarate receptor 1 (Alpha-ketoglutarate receptor 1) (G-protein coupled receptor 80) (G-protein coupled receptor 99) (P2Y purinoceptor 15) (P2Y15) (P2Y-like GPCR) (P2Y-like nucleotide receptor)OXGR1 GPR80 GPR99 P2RY15 P2Y15Q96P682
26S protease regulatory subunit 10B (26S proteasome AAA-ATPase subunit RPT4) (Proteasome 26S subunit ATPase 6) (Proteasome subunit p42)PSMC6 SUG2P497192
26S protease regulatory subunit 4 (P26s4) (26S proteasome AAA-ATPase subunit RPT2) (Proteasome 26S subunit ATPase 1)PSMC1Q6IAW02
26S protease regulatory subunit 6A (26S proteasome AAA-ATPase subunit RPT5) (Proteasome 26S subunit ATPase 3) (Proteasome subunit P50) (Tat-binding protein 1) (TBP-1)PSMC3 TBP1Q3B7572
26S protease regulatory subunit 8 (26S proteasome AAA-ATPase subunit RPT6) (Proteasome 26S subunit ATPase 5) (Proteasome subunit p45) (Thyroid hormone receptor-interacting protein 1) (TRIP1) (p45/SUG)PSMC5 SUG1P472102
26S proteasome non-ATPase regulatory subunit 1PSMD1A0A087WW662
26S proteasome non-ATPase regulatory subunit 1 (26S proteasome regulatory subunit RPN2) (26S proteasome regulatory subunit S1) (26S proteasome subunit p112)PSMD1Q6GMU52
26S proteasome non-ATPase regulatory subunit 11 (Fragment)PSMD11J3QRY42
26S proteasome non-ATPase regulatory subunit 12 (26S proteasome regulatory subunit RPN5) (26S proteasome regulatory subunit p55)PSMD12A6NP152
26S proteasome non-ATPase regulatory subunit 13 (26S proteasome regulatory subunit RPN9) (26S proteasome regulatory subunit S11) (26S proteasome regulatory subunit p40.5)PSMD13Q53XU22
26S proteasome non-ATPase regulatory subunit 2 (Fragment)PSMD2H7C1H22
26S proteasome non-ATPase regulatory subunit 3PSMD3F5H8K42
26S proteasome non-ATPase regulatory subunit 5PSMD5F2Z3J22
26S proteasome non-ATPase regulatory subunit 5 (26S protease subunit S5 basic) (26S proteasome subunit S5B)PSMD5 KIAA0072B4DZM82
26S proteasome non-ATPase regulatory subunit 6 (26S proteasome regulatory subunit RPN7) (26S proteasome regulatory subunit S10) (Breast cancer-associated protein SGA-113M) (Phosphonoformate immuno-associated protein 4) (Proteasome regulatory particle subunit p44S10) (p42A)PSMD6 KIAA0107 PFAAP4Q6UV222
26S proteasome non-ATPase regulatory subunit 7 (26S proteasome regulatory subunit RPN8) (26S proteasome regulatory subunit S12) (Mov34 protein homolog) (Proteasome subunit p40)PSMD7 MOV34LQ6PKI22
26S proteasome non-ATPase regulatory subunit 8 (Fragment)PSMD8K7EJR32
26S proteasome non-ATPase regulatory subunit 9PSMD9J3KN292
26S proteasome non-ATPase regulatory subunit 9PSMD9F5H7X12
26S proteasome non-ATPase regulatory subunit 9 (26S proteasome regulatory subunit p27)PSMD9B2RD352
26S proteasome regulatory subunit 10BPSMC6H0YJE92
26S proteasome regulatory subunit 10B (Fragment)PSMC6H0YJS82
26S proteasome regulatory subunit 4 (Fragment)PSMC1G3V4X12
28S ribosomal protein S24, mitochondrial (MRP-S24) (S24mt) (Mitochondrial small ribosomal subunit protein uS3m) (bMRP-47) (bMRP47)MRPS24 HSPC335Q96EL22
3-ketoacyl-CoA thiolase, mitochondrialACAA2A0A0B4J2A42
3-phosphoglycerate dehydrogenase (Fragment)0Q96RV52
39S ribosomal protein L37, mitochondrial (Fragment)MRPL37H0Y4J22
39S ribosomal protein L51, mitochondrial (L51mt) (MRP-L51) (Mitochondrial large ribosomal subunit protein mL51) (bMRP-64) (bMRP64)MRPL51 MRP64 CDA09 HSPC241Q4U2R62
39S ribosomal protein L54, mitochondrial (L54mt) (MRP-L54) (Mitochondrial large ribosomal subunit protein mL54)MRPL54Q6P1612
4-trimethylaminobutyraldehyde dehydrogenase (TMABADH) (EC 1.2.1.47) (Aldehyde dehydrogenase E3 isozyme) (Aldehyde dehydrogenase family 9 member A1) (EC 1.2.1.3) (Gamma-aminobutyraldehyde dehydrogenase) (EC 1.2.1.19) (R-aminobutyraldehyde dehydrogenase) [Cleaved into: 4-trimethylaminobutyraldehyde dehydrogenase, N-terminally processed]ALDH9A1 ALDH4 ALDH7 ALDH9Q5VV902
40S ribosomal protein S10RPS10F6U2112
40S ribosomal protein S12 (Small ribosomal subunit protein eS12)RPS12Q76M582
40S ribosomal protein S13 (Small ribosomal subunit protein uS15)RPS13Q498Y02
40S ribosomal protein S14 (Fragment)RPS14H0YB222
40S ribosomal protein S14 (Small ribosomal subunit protein uS11)RPS14 PRO2640B2R5G52
40S ribosomal protein S15 (RIG protein) (Small ribosomal subunit protein uS19)RPS15 RIGA5D8V92
40S ribosomal protein S15aRPS15AH3BV272
40S ribosomal protein S15aRPS15AI3L3P72
40S ribosomal protein S18 (Ke-3) (Ke3) (Small ribosomal subunit protein uS13)RPS18 D6S218EQ5SUJ32
40S ribosomal protein S2RPS2E9PM362
40S ribosomal protein S23 (Small ribosomal subunit protein uS12)RPS23Q6IB082
40S ribosomal protein S24 (Small ribosomal subunit protein eS24)RPS24Q7Z3D12
40S ribosomal protein S24 (Small ribosomal subunit protein eS24)RPS24E7EPK62
40S ribosomal protein S25 (Small ribosomal subunit protein eS25)RPS25P251112
40S ribosomal protein S26 (Small ribosomal subunit protein eS26)RPS26Q3MHD82
40S ribosomal protein S27RPS27Q5T4L42
40S ribosomal protein S27RPS27LH0YMV82
40S ribosomal protein S3 (EC 4.2.99.18) (Small ribosomal subunit protein uS3)RPS3 OK/SW-cl.26B2R7N52
40S ribosomal protein S3 (Fragment)RPS3H0YCJ72
40S ribosomal protein S3a (Fragment)RPS3AH0Y9Y42
40S ribosomal protein S3a (Fragment)RPS3AD6RB092
40S ribosomal protein S3a (Small ribosomal subunit protein eS1) (v-fos transformation effector protein) (Fte-1)RPS3A FTE1 MFTLP492412
40S ribosomal protein S4, X isoform (SCR10) (Single copy abundant mRNA protein) (Small ribosomal subunit protein eS4)RPS4X CCG2 RPS4 SCARP558312
40S ribosomal protein S5RPS5M0QZN22
40S ribosomal protein S5 (Small ribosomal subunit protein uS7) [Cleaved into: 40S ribosomal protein S5, N-terminally processed]RPS5B2R4T22
40S ribosomal protein S6RPS6 hCG_1741512A2A3R62
40S ribosomal protein S6 (Phosphoprotein NP33) (Small ribosomal subunit protein eS6)RPS6 OK/SW-cl.2Q8N6Z72
40S ribosomal protein S7 (Small ribosomal subunit protein eS7)RPS7Q6IPH12
40S ribosomal protein S9 (Small ribosomal subunit protein uS4)RPS9Q4QRK72
45 kDa calcium-binding protein (Cab45) (Stromal cell-derived factor 4) (SDF-4)SDF4 CAB45 PSEC0034Q9NZP72
45 kDa calcium-binding protein (Fragment)SDF4H0Y3T62
4F2 cell-surface antigen heavy chain (4F2hc) (4F2 heavy chain antigen) (Lymphocyte activation antigen 4F2 large subunit) (Solute carrier family 3 member 2) (CD antigen CD98)SLC3A2 MDU1Q135432
5'(3')-deoxyribonucleotidase, cytosolic typeNT5CJ3KRC42
5'-AMP-activated protein kinase subunit gamma-1 (Fragment)PRKAG1H0YIC92
5'-nucleotidase (5'-NT) (EC 3.1.3.5) (Ecto-5'-nucleotidase) (CD antigen CD73)NT5E NT5 NTEQ5W1162
5'-nucleotidase, ecto (CD73)NT5EQ6NZX32
5-demethoxyubiquinone hydroxylase, mitochondrial (DMQ hydroxylase) (EC 1.14.13.-) (Timing protein clk-1 homolog) (Ubiquinone biosynthesis monooxygenase COQ7)COQ7Q998072
5-hydroxytryptamine receptor 2A (5-HT-2) (5-HT-2A) (Serotonin receptor 2A)HTR2A HTR2P282232
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 (6PF-2-K/Fru-2,6-P2ase 4) (PFK/FBPase 4) (6PF-2-K/Fru-2,6-P2ase testis-type isozyme) [Includes: 6-phosphofructo-2-kinase (EC 2.7.1.105); Fructose-2,6-bisphosphatase (EC 3.1.3.46)]PFKFB4Q168772
6-phosphogluconate dehydrogenase, decarboxylating (EC 1.1.1.44)PGD PGDHA8K2Y92
6-phosphogluconate dehydrogenase, decarboxylating (Fragment)PGDK7EM492
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