EVpedia provide top 100+ EV markers, selected according to their identification number.
Based on EV proteomes, we defined the identification number of protein A as the number of datasets which contain protein A.
Therefore, proteins with higher identification numbers were more conserved.

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Protein name Gene symbol UniProt accession Identification number
Activating molecule in BECN1-regulated autophagy protein 1AMBRA1 KIAA1736Q9C0C72
Activator of 90 kDa heat shock protein ATPase homolog 1 (AHA1) (p38)AHSA1 C14orf3 HSPC322Q96IL62
Activin receptor type-2A (EC 2.7.11.30) (Activin receptor type IIA) (ACTR-IIA) (ACTRIIA)ACVR2A ACVR2P270372
Acyl-CoA thioesterase 1ACOT1A1L1722
Acyl-Coenzyme A dehydrogenase family, member 9 variant (Fragment)0Q59FN32
Acyl-Coenzyme A dehydrogenase, C-4 to C-12 straight chain, isoform CRA_a (Medium-chain-specific acyl-CoA dehydrogenase, mitochondrial)ACADM hCG_22915Q5T4U52
Acyl-Coenzyme A dehydrogenase, very long chain variant (Fragment)0Q53HR22
Acyl-coenzyme A synthetase ACSM1, mitochondrial (EC 6.2.1.2) (Acyl-CoA synthetase medium-chain family member 1) (Butyrate--CoA ligase 1) (Butyryl-coenzyme A synthetase 1) (Lipoate-activating enzyme) (Middle-chain acyl-CoA synthetase 1)ACSM1 BUCS1 LAE MACS1Q08AH12
Acyl-coenzyme A thioesterase 13 (Acyl-CoA thioesterase 13) (EC 3.1.2.-) (Thioesterase superfamily member 2) [Cleaved into: Acyl-coenzyme A thioesterase 13, N-terminally processed]ACOT13 THEM2 HT012 PNAS-27F5H2L42
Acyl-coenzyme A thioesterase 8 (Acyl-CoA thioesterase 8) (EC 3.1.2.27) (Choloyl-coenzyme A thioesterase) (HIV-Nef-associated acyl-CoA thioesterase) (PTE-2) (Peroxisomal acyl-coenzyme A thioester hydrolase 1) (PTE-1) (Peroxisomal long-chain acyl-CoA thioesterase 1) (Thioesterase II) (hACTE-III) (hACTEIII) (hTE)ACOT8 ACTEIII PTE1 PTE2O147342
Acyl-protein thioesterase 2 (Fragment)LYPLA2Q5QPN52
Acylamino-acid-releasing enzyme (AARE) (EC 3.4.19.1) (Acyl-peptide hydrolase) (APH) (Acylaminoacyl-peptidase) (Oxidized protein hydrolase) (OPH)APEH D3F15S2 D3S48E DNF15S2Q9P0Y22
ADAMTS-like protein 5 (ADAMTSL-5) (Thrombospondin type-1 domain-containing protein 6)ADAMTSL5 THSD6Q6ZMM22
Adaptin ear-binding coat-associated protein 2NECAP2D6RB242
Adaptor-related protein complex 2, alpha 2 subunit variant (Fragment)0Q59FN82
Adducin 3 isoform a variant (Fragment)0Q59EK12
Adenine phosphoribosyltransferaseAPRTH3BSW32
Adenine phosphoribosyltransferase (APRT) (EC 2.4.2.7)APRTQ3KP552
Adenine phosphoribosyltransferase (Fragment)APRTH3BQF12
Adenosine deaminase, RNA-specific isoform ADAR-a variant (Fragment)0Q59EC02
Adenosine kinase (AK) (EC 2.7.1.20) (Adenosine 5'-phosphotransferase)ADKQ9BTN22
Adenosine kinase (AK) (EC 2.7.1.20) (Adenosine 5'-phosphotransferase)ADKB7Z8002
Adenosine receptor A1ADORA1P305422
Adenosine receptor A2aADORA2A ADORA2P292742
Adenosine receptor A2bADORA2BP292752
Adenosylhomocysteinase (AdoHcyase) (EC 3.3.1.1) (S-adenosyl-L-homocysteine hydrolase)AHCY SAHHF5H7372
Adenosylhomocysteinase (AdoHcyase) (EC 3.3.1.1) (S-adenosyl-L-homocysteine hydrolase)AHCY SAHHA8K3072
Adenosylhomocysteinase (EC 3.3.1.1) (Fragment)AHCYL1Q2NKW82
Adenylate cyclase type 2 (EC 4.6.1.1) (ATP pyrophosphate-lyase 2) (Adenylate cyclase type II) (Adenylyl cyclase 2)ADCY2 KIAA1060Q084622
Adenylate kinase isoenzyme 1 (Fragment)AK1H0Y4J62
Adenylosuccinate synthetase isozyme 2 (AMPSase 2) (AdSS 2) (EC 6.3.4.4) (Adenylosuccinate synthetase, acidic isozyme) (Adenylosuccinate synthetase, liver isozyme) (L-type adenylosuccinate synthetase) (IMP--aspartate ligase 2)ADSS ADSS2Q96EG72
Adenylyl cyclase-associated protein0B2RDY92
Adenylyl cyclase-associated protein 1 (CAP 1)CAP1 CAPQ5T0S12
Adenylyl cyclase-associated protein 1 (Fragment)CAP1Q5T0R32
Adhesion G protein-coupled receptor A1 (G-protein coupled receptor 123)ADGRA1 GPR123 KIAA1828Q86SQ62
Adhesion G protein-coupled receptor L3 (Calcium-independent alpha-latrotoxin receptor 3) (CIRL-3) (Latrophilin-3) (Lectomedin-3)ADGRL3 KIAA0768 LEC3 LPHN3Q9HAR22
Adipocyte plasma membrane-associated protein (Protein BSCv)APMAP C20orf3 UNQ1869/PRO4305Q9NUB22
ADM [Cleaved into: Adrenomedullin (AM); Proadrenomedullin N-20 terminal peptide (ProAM N-terminal 20 peptide) (PAMP) (ProAM-N20)]ADM AMP353182
ADP-ribosylation factor 1ARF1P328892
ADP-ribosylation factor 3 (Fragment)ARF3F5H1V12
ADP-ribosylation factor 4ARF4 ARF2B2R7J72
ADP-ribosylation factor 5ARF5P264372
ADP-ribosylation factor 6ARF6P264382
ADP-ribosylation factor-like protein 15ARL15A0A087WUW92
ADP-ribosylation factor-like protein 4AARL4A ARL4P406172
ADP-ribosylation factor-like protein 4D (ADP-ribosylation factor-like protein 4L)ARL4D ARF4LP497032
ADP-ribosylation factor-like protein 6-interacting protein 1 (Fragment)ARL6IP1H3BPJ22
ADP-sugar pyrophosphataseNUDT5A6NCQ02
ADP/ATP translocase 1SLC25A4V9GYG02
AF4/FMR2 family member 1 (ALL1-fused gene from chromosome 4 protein) (Protein AF-4) (Protein FEL) (Proto-oncogene AF4)AFF1 AF4 FEL MLLT2 PBM1P518252
AF4/FMR2 family member 3 (Lymphoid nuclear protein related to AF4) (Protein LAF-4)AFF3 LAF4P518262
AfadinAFDNQ5TIG52
Aflatoxin B1 aldehyde reductase member 2 (EC 1.1.1.n11) (AFB1 aldehyde reductase 1) (AFB1-AR 1) (Aldoketoreductase 7) (Succinic semialdehyde reductase) (SSA reductase)AKR7A2 AFAR AFAR1 AKR7Q5TG632
Age-related maculopathy susceptibility protein 2ARMS2P0C7Q22
Aging-associated protein 14a0Q1XBU72
Aging-associated protein 14b0Q1XBU62
Agrin [Cleaved into: Agrin N-terminal 110 kDa subunit; Agrin C-terminal 110 kDa subunit; Agrin C-terminal 90 kDa fragment (C90); Agrin C-terminal 22 kDa fragment (C22)]AGRN AGRINQ8N4J52
AHNAK nucleoproteinAHNAKQ96EC42
Alanyl-tRNA-editing protein Aarsd1AARSD1K7N7992
Aldehyde dehydrogenase family 16 member A1 (Fragment)ALDH16A1M0QY062
Aldehyde dehydrogenase, mitochondrial (EC 1.2.1.3) (ALDH class 2) (ALDH-E2) (ALDHI)ALDH2 ALDME7EUE52
ALDH3A1 protein (Fragment)ALDH3A1Q6PKA62
Aldo-keto reductase family 1 member C2 (cDNA FLJ52680, highly similar to Aldo-keto reductase family 1 member C2 (EC 1.-.-.-))AKR1C2B4DK692
ALK and LTK ligand 2 (Augmentor alpha) (AUG-alpha) (Protein FAM150B)ALKAL2 FAM150B UNQ542/PRO1097Q6UX462
Alkaline phosphatase, placental type (EC 3.1.3.1) (Alkaline phosphatase Regan isozyme) (Placental alkaline phosphatase 1) (PLAP-1)ALPP PLAPP051882
Alpha subunit of GsGTP binding protein (Fragment)GSAQ144552
Alpha-(1,6)-fucosyltransferase (Alpha1-6FucT) (EC 2.4.1.68) (Fucosyltransferase 8) (GDP-L-Fuc:N-acetyl-beta-D-glucosaminide alpha1,6-fucosyltransferase) (GDP-fucose--glycoprotein fucosyltransferase) (Glycoprotein 6-alpha-L-fucosyltransferase)FUT8Q8IUA52
Alpha-1 antitrypsin (Fragment)0Q137472
Alpha-1,2-mannosyltransferase ALG9 (EC 2.4.1.259) (EC 2.4.1.261) (Asparagine-linked glycosylation protein 9 homolog) (Disrupted in bipolar disorder protein 1) (Dol-P-Man:Man(6)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase) (Dol-P-Man:Man(8)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase)ALG9 DIBD1Q9H6U82
Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase A (EC 2.4.1.145) (N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase IVa) (GlcNAc-T IVa) (GnT-IVa) (N-acetylglucosaminyltransferase IVa) (UDP-N-acetylglucosamine: alpha-1,3-D-mannoside beta-1,4-N-acetylglucosaminyltransferase IVa) [Cleaved into: Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase A soluble form]MGAT4AQ9UM212
Alpha-1-antichymotrypsin (Fragment)SERPINA3G3V5I32
Alpha-1-syntrophin (59 kDa dystrophin-associated protein A1 acidic component 1) (Pro-TGF-alpha cytoplasmic domain-interacting protein 1) (TACIP1) (Syntrophin-1)SNTA1 SNT1Q134242
Alpha-1B adrenergic receptor (Alpha-1B adrenoreceptor) (Alpha-1B adrenoceptor)ADRA1BP353682
Alpha-1D adrenergic receptor (Alpha-1A adrenergic receptor) (Alpha-1D adrenoreceptor) (Alpha-1D adrenoceptor) (Alpha-adrenergic receptor 1a)ADRA1D ADRA1AP251002
Alpha-2-HS-glycoprotein (Alpha-2-Z-globulin) (Ba-alpha-2-glycoprotein) (Fetuin-A) [Cleaved into: Alpha-2-HS-glycoprotein chain A; Alpha-2-HS-glycoprotein chain B]AHSG FETUA PRO2743B2R7G12
Alpha-actinin-1 (Alpha-actinin cytoskeletal isoform) (F-actin cross-linking protein) (Non-muscle alpha-actinin-1)ACTN1B7TY162
Alpha-actinin-4 (Non-muscle alpha-actinin 4)ACTN4O760482
Alpha-aminoadipic semialdehyde dehydrogenase (Alpha-AASA dehydrogenase) (EC 1.2.1.31) (Aldehyde dehydrogenase family 7 member A1) (EC 1.2.1.3) (Antiquitin-1) (Betaine aldehyde dehydrogenase) (EC 1.2.1.8) (Delta1-piperideine-6-carboxylate dehydrogenase) (P6c dehydrogenase)ALDH7A1 ATQ1Q9BUL42
Alpha-hemoglobin-stabilizing protein (Erythroid differentiation-related factor) (Erythroid-associated factor)AHSP EDRF ERAFQ9NZD42
Alpha-mannosidase (EC 3.2.1.-)MAN2A1A5PKX52
Alpha-mannosidase (EC 3.2.1.-) (Fragment)0Q59E902
Alpha-mannosidase (EC 3.2.1.-) (Fragment)MAN2A2H0YLB92
Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6 (EC 2.4.99.-) (GalNAc alpha-2,6-sialyltransferase VI) (ST6GalNAc VI) (ST6GalNAcVI) (hST6GalNAc VI) (Sialyltransferase 7F) (SIAT7-F)ST6GALNAC6 SIAT7F UNQ708/PRO1359Q969X22
Alpha-N-acetylglucosaminidase (Fragment)NAGLUK7EQH92
Alpha-soluble NSF attachment proteinNAPAM0QZM92
Alpha-soluble NSF attachment protein (SNAP-alpha) (N-ethylmaleimide-sensitive factor attachment protein alpha)NAPA SNAPAQ9BVJ32
Alpha-tocopherol transfer protein-likeTTPAL C20orf121Q9BTX72
Amine oxidase (EC 1.4.3.-) (Fragment)AOC1C9J0G82
Amino acid transporterSLC1A3Q8N1692
Amino-terminal enhancer of split (Amino enhancer of split) (Gp130-associated protein GAM) (Grg-5) (Groucho-related protein 5) (Protein ESP1) (Protein GRG)AES GRG GRG5Q081172
Aminoacyl tRNA synthase complex-interacting multifunctional protein 2AIMP2F8W9502
Aminoacylase-1ACY1F8WC592
Aminopeptidase (EC 3.4.11.-)0A8K6H12
Aminopeptidase N (AP-N) (hAPN) (EC 3.4.11.2) (Alanyl aminopeptidase) (Aminopeptidase M) (AP-M) (Microsomal aminopeptidase) (Myeloid plasma membrane glycoprotein CD13) (gp150) (CD antigen CD13)ANPEP APN CD13 PEPNQ167282
Aminopeptidase N (Fragment)ANPEPH0YMC12
Aminopeptidase RNPEPL1 (Fragment)RNPEPL1C9JSI22
Amyloid beta A4 precursor protein-binding family A member 2 (Adapter protein X11beta) (Neuron-specific X11L protein) (Neuronal Munc18-1-interacting protein 2) (Mint-2)APBA2 MINT2 X11LQ997672
Amyloid beta A4 precursor protein-binding family B member 2 (Protein Fe65-like 1)APBB2 FE65L FE65L1Q928702
Amyloid beta A4 protein (ABPP) (APPI) (APP) (Alzheimer disease amyloid protein) (Amyloid precursor protein) (Beta-amyloid precursor protein) (Cerebral vascular amyloid peptide) (CVAP) (PreA4) (Protease nexin-II) (PN-II) [Cleaved into: N-APP; Soluble APP-alpha (S-APP-alpha); Soluble APP-beta (S-APP-beta); C99; Beta-amyloid protein 42 (Beta-APP42); Beta-amyloid protein 40 (Beta-APP40); C83; P3(42); P3(40); C80; Gamma-secretase C-terminal fragment 59 (Amyloid intracellular domain 59) (AICD-59) (AID(59)) (Gamma-CTF(59)); Gamma-secretase C-terminal fragment 57 (Amyloid intracellular domain 57) (AICD-57) (AID(57)) (Gamma-CTF(57)); Gamma-secretase C-terminal fragment 50 (Amyloid intracellular domain 50) (AICD-50) (AID(50)) (Gamma-CTF(50)); C31]APP A4 AD1Q9UCD12
Amyloid lambda 6 light chain variable region SAR (Fragment)0Q96JD02
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