EVpedia provide top 100+ EV markers, selected according to their identification number.
Based on EV proteomes, we defined the identification number of protein A as the number of datasets which contain protein A.
Therefore, proteins with higher identification numbers were more conserved.

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Protein name Gene symbol UniProt accession Identification number
Amyloid-beta A4 precursor protein-binding family B member 1 (Protein Fe65)APBB1 FE65 RIRO002132
AN1-type zinc finger protein 1ZFAND1Q8TCF12
AN1-type zinc finger protein 5 (Zinc finger A20 domain-containing protein 2) (Zinc finger protein 216)ZFAND5 ZA20D2 ZNF216O760802
Anamorsin (Fragment)CIAPIN1H3BQ232
Anaphase-promoting complex subunit 13 (APC13) (Cyclosome subunit 13)ANAPC13Q9BS182
Anaphase-promoting complex subunit 4 (Fragment)ANAPC4D6RAP62
Anaphase-promoting complex subunit 5ANAPC5F5H0F92
Anaphase-promoting complex subunit CDC26 (Anaphase-promoting complex subunit 12) (APC12) (Cell division cycle protein 26 homolog)CDC26 ANAPC12 C9orf17Q8NHZ82
Anchor proteinRESDA1Q5Y1902
Androglobin (Calpain-7-like protein)ADGB C6orf103 CAPN7LQ8N7X02
Angio-associated migratory cell protein (Fragment)AAMPC9JTS32
Angiomotin-like protein 2 (Leman coiled-coil protein) (LCCP)AMOTL2 KIAA0989Q9Y2J42
Angiopoietin-2 (ANG-2)ANGPT2O151232
Angiopoietin-related protein 5 (Angiopoietin-like protein 5)ANGPTL5 UNQ5795/PRO19600Q86XS52
Angiotensin-converting enzymeACEA0A0A0MSN42
Angiotensinogen (Serpin peptidase inhibitor, clade A, member 8) (Angiotensinogen (Serpin peptidase inhibitor, clade A, member 8), isoform CRA_a)AGT hCG_14741B0ZBE22
Anion exchange protein 1 (Fragment)SLC4A1E2J8242
ANKRD26 proteinANKRD26A1L4972
Ankyrin and armadillo repeat-containing proteinANKARQ7Z5J82
Ankyrin repeat and BTB/POZ domain-containing protein 2ABTB2Q8N9612
Ankyrin repeat and MYND domain-containing protein 2ANKMY2Q8IV382
Ankyrin repeat and protein kinase domain-containing protein 1 (EC 2.7.11.1) (Protein kinase PKK2) (Sugen kinase 288) (SgK288) (X-kinase)ANKK1 PKK2 SGK288Q8NFD22
Ankyrin repeat domain-containing protein 20A1ANKRD20A1 ANKRD20AQ5TYW22
Ankyrin repeat domain-containing protein 20A4ANKRD20A4Q4UJ752
Ankyrin repeat domain-containing protein 24ANKRD24 KIAA1981Q8TF212
Ankyrin repeat domain-containing protein 26ANKRD26 KIAA1074Q9UPS82
Ankyrin repeat domain-containing protein 30AANKRD30AR4GNA22
Ankyrin repeat domain-containing protein 30B (Serologically defined breast cancer antigen NY-BR-1.1)ANKRD30BQ9BXX22
Ankyrin repeat domain-containing protein 36CANKRD36CE9PJI02
Ankyrin repeat domain-containing protein 40ANKRD40Q6AI122
Ankyrin repeat domain-containing protein 46 (Ankyrin repeat small protein) (ANK-S)ANKRD46Q86W742
Ankyrin repeat domain-containing protein 50ANKRD50 KIAA1223Q9ULJ72
Ankyrin repeat domain-containing protein 53ANKRD53Q8N9V62
Ankyrin repeat domain-containing protein 65ANKRD65E5RJM62
Annexin0B4DL192
Annexin0B4DNH82
Annexin0A8K2L62
Annexin (Fragment)ANXA6E5RJF52
Annexin A11 (56 kDa autoantigen) (Annexin XI) (Annexin-11) (Calcyclin-associated annexin 50) (CAP-50)ANXA11 ANX11B4DVE72
Annexin A4 (35-beta calcimedin) (Annexin IV) (Annexin-4) (Carbohydrate-binding protein p33/p41) (Chromobindin-4) (Endonexin I) (Lipocortin IV) (P32.5) (PP4-X) (Placental anticoagulant protein II) (PAP-II) (Protein II)ANXA4 ANX4Q96F332
Annexin A5 (Anchorin CII) (Annexin V) (Annexin-5) (Calphobindin I) (CBP-I) (Endonexin II) (Lipocortin V) (Placental anticoagulant protein 4) (PP4) (Placental anticoagulant protein I) (PAP-I) (Thromboplastin inhibitor) (Vascular anticoagulant-alpha) (VAC-alpha)ANXA5 ANX5 ENX2 PP4Q6FI162
Annexin A7 (Annexin VII) (Annexin-7) (Synexin)ANXA7 ANX7 SNX OK/SW-cl.95Q5T0M62
Anoctamin-1 (Discovered on gastrointestinal stromal tumors protein 1) (Oral cancer overexpressed protein 2) (Transmembrane protein 16A) (Tumor-amplified and overexpressed sequence 2)ANO1 DOG1 ORAOV2 TAOS2 TMEM16AA8KAM32
Anoctamin-6 (Small-conductance calcium-activated nonselective cation channel) (SCAN channel) (Transmembrane protein 16F)ANO6 TMEM16FQ8N3Q22
Anoctamin-9 (Transmembrane protein 16J) (Tumor protein p53-inducible protein 5) (p53-induced gene 5 protein)ANO9 PIG5 TMEM16J TP53I5A1A5B42
Anti-(ED-B) scFV (Fragment)0A2KBC22
Anti-streptococcal/anti-myosin immunoglobulin lambda light chain variable region (Fragment)0Q96SB02
Anti-thyroglobulin light chain variable region (Fragment)0Q8IZD82
AP-1 complex subunit beta-1 (Fragment)AP1B1C9J1E72
AP-1 complex subunit gamma-1 (Adaptor protein complex AP-1 subunit gamma-1) (Adaptor-related protein complex 1 subunit gamma-1) (Clathrin assembly protein complex 1 gamma-1 large chain) (Gamma1-adaptin) (Golgi adaptor HA1/AP1 adaptin subunit gamma-1)AP1G1 ADTG CLAPG1Q9UG092
AP-1 complex subunit mu-1 (AP-mu chain family member mu1A) (Adaptor protein complex AP-1 subunit mu-1) (Adaptor-related protein complex 1 subunit mu-1) (Clathrin assembly protein complex 1 mu-1 medium chain 1) (Clathrin coat assembly protein AP47) (Clathrin coat-associated protein AP47) (Golgi adaptor HA1/AP1 adaptin mu-1 subunit) (Mu-adaptin 1) (Mu1A-adaptin)AP1M1 CLTNMQ4TTY52
AP-1 complex subunit mu-2 (Fragment)AP1M2K7EPR42
AP-1 complex-associated regulatory protein (2c18) (Adaptor-related protein complex 1-associated regulatory protein) (Gamma-1-adaptin brefeldin A resistance protein) (GBAR) (Gamma-BAR) (Gamma-A1-adaptin and kinesin interactor) (Gadkin)AP1AR C4orf16 PRO0971Q63HQ02
AP-2 complex subunit alpha-1 (100 kDa coated vesicle protein A) (Adaptor protein complex AP-2 subunit alpha-1) (Adaptor-related protein complex 2 subunit alpha-1) (Alpha-adaptin A) (Alpha1-adaptin) (Clathrin assembly protein complex 2 alpha-A large chain) (Plasma membrane adaptor HA2/AP2 adaptin alpha A subunit)AP2A1 ADTAA CLAPA1Q96CI72
AP-2 complex subunit beta (Fragment)AP2B1K7EJ012
AP-2 complex subunit muAP2M1A0A087WY712
AP-2 complex subunit mu (AP-2 mu chain) (Adaptin-mu2) (Adaptor protein complex AP-2 subunit mu) (Adaptor-related protein complex 2 subunit mu) (Clathrin assembly protein complex 2 mu medium chain) (Clathrin coat assembly protein AP50) (Clathrin coat-associated protein AP50) (HA2 50 kDa subunit) (Plasma membrane adaptor AP-2 50 kDa protein)AP2M1 CLAPM1 KIAA0109A6NE122
AP-2 complex subunit sigmaAP2S1X6R3902
AP-3 complex subunit beta-1 (Adaptor protein complex AP-3 subunit beta-1) (Adaptor-related protein complex 3 subunit beta-1) (Beta-3A-adaptin) (Clathrin assembly protein complex 3 beta-1 large chain)AP3B1 ADTB3AQ7Z3932
AP-3 complex subunit beta-1 (Adaptor protein complex AP-3 subunit beta-1) (Adaptor-related protein complex 3 subunit beta-1) (Beta-3A-adaptin) (Clathrin assembly protein complex 3 beta-1 large chain)AP3B1 ADTB3AE5RJ682
AP-3 complex subunit mu-2 (Adaptor-related protein complex 3 subunit mu-2) (Clathrin assembly protein assembly protein complex 3 mu-2 medium chain) (Clathrin coat assembly protein AP47 homolog 2) (Clathrin coat-associated protein AP47 homolog 2) (Golgi adaptor AP-1 47 kDa protein homolog 2) (HA1 47 kDa subunit homolog 2) (Mu3B-adaptin) (P47B)AP3M2P536772
AP-3 complex subunit sigma-2 (Adaptor-related protein complex 3, sigma 2 subunit, isoform CRA_d)AP3S2 hCG_27218H0YLI72
AP-5 complex subunit sigma-1 (Adaptor-related protein complex 5 sigma subunit) (Sigma5)AP5S1 C20orf29Q9NUS52
APC membrane recruitment protein 1 (Amer1) (Protein FAM123B) (Wilms tumor gene on the X chromosome protein)AMER1 FAM123B WTXQ5JTC62
APOC2 protein (Apolipoprotein C-II)APOC2Q6P1632
Apolipoprotein A-IIAPOA2V9GYM32
Apolipoprotein E (Fragment)APOEH0Y7L52
Apolipoprotein MAPOMQ5SRP52
Apoptosis inhibitor 5API5G3V1C32
Apoptosis inhibitor 5 (API-5) (Antiapoptosis clone 11 protein) (AAC-11) (Cell migration-inducing gene 8 protein) (Fibroblast growth factor 2-interacting factor) (FIF) (Protein XAGL)API5 MIG8O154412
Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B)PPP1R13B ASPP1 KIAA0771Q96KQ42
Apoptotic chromatin condensation inducer in the nucleusACIN1S4R3H42
Aprataxin (EC 3.-.-.-) (Forkhead-associated domain histidine triad-like protein) (FHA-HIT)APTX AXA1Q7Z2E32
Aquaporin-9 (AQP-9) (Aquaglyceroporin-9) (Small solute channel 1)AQP9 SSC1O433152
Archaemetzincin-2 (EC 3.4.-.-) (Archeobacterial metalloproteinase-like protein 2)AMZ2 BM-014Q86W342
Arf-GAP domain and FG repeat-containing protein 2 (HIV-1 Rev-binding protein-like protein) (Rev/Rex activation domain-binding protein related) (RAB-R)AGFG2 HRBL RABRO950812
Arf-GAP with dual PH domain-containing protein 2 (Centaurin-alpha-2) (Cnt-a2)ADAP2 CENTA2Q9NPF82
Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 6 (AGAP-6) (Centaurin-gamma-like family member 3)AGAP6 CTGLF3Q5VW222
Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 (Fragment)ASAP1H0YBF72
Arginine--tRNA ligase, cytoplasmic (EC 6.1.1.19) (Arginyl-tRNA synthetase) (ArgRS)RARSQ53GY42
Arginine-glutamic acid dipeptide repeats protein (Fragment)REREK7EJQ12
Armadillo repeat protein deleted in velo-cardio-facial syndromeARVCFC9JJX62
Armadillo repeat-containing X-linked protein 4ARMCX4F8W8Y72
ARP2 actin-related protein 2 homolog (Yeast), isoform CRA_d (Actin-related protein 2)ACTR2 hCG_21224F5H6T12
ARPC4-TTLL3 readthroughARPC4-TTLL3F8WE392
Arrestin-C (Cone arrestin) (C-arrestin) (cArr) (Retinal cone arrestin-3) (X-arrestin)ARR3 ARRX CARP365752
Aryl hydrocarbon receptor (Ah receptor) (AhR) (Class E basic helix-loop-helix protein 76) (bHLHe76)AHR BHLHE76P358692
Aryl hydrocarbon receptor nuclear translocator 2 (ARNT protein 2) (Class E basic helix-loop-helix protein 1) (bHLHe1)ARNT2 BHLHE1 KIAA0307Q9HBZ22
Arylacetamide deacetylase-like 1 (Neutral cholesterol ester hydrolase 1)NCEH1 AADACL1 hCG_20251A0A0R4J2G32
Arylamine N-acetyltransferase 1NAT1F5H5R82
Arylsulfatase K (ASK) (EC 3.1.6.-) (Telethon sulfatase)ARSK TSULF UNQ630/PRO1246Q6UWY02
Asialoglycoprotein receptor 2 (ASGP-R 2) (ASGPR 2) (C-type lectin domain family 4 member H2) (Hepatic lectin H2) (HL-2)ASGR2 CLEC4H2P073072
Asparagine synthetase [glutamine-hydrolyzing] (EC 6.3.5.4) (Cell cycle control protein TS11) (Glutamine-dependent asparagine synthetase)ASNS TS11E9PCI32
Aspartate aminotransferase (EC 2.6.1.1)0A8K4822
Aspartate--tRNA ligase, cytoplasmic (Fragment)DARSH7C2782
Aspartate--tRNA ligase, cytoplasmic (Fragment)DARSC9J7S32
Aspartate--tRNA ligase, cytoplasmic (Fragment)DARSC9JQM92
Aspartyl aminopeptidase (EC 3.4.11.21)DNPEP ASPEP DAPQ9NV552
Aspartyl aminopeptidase (Fragment)DNPEPB9ZVU22
Astrotactin-1ASTN1B1AJS12
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